DK0533840T3 - Behandling af kronisk nyresvigt med imidazol-angiotensin-II-receptor-antagonister - Google Patents

Behandling af kronisk nyresvigt med imidazol-angiotensin-II-receptor-antagonister

Info

Publication number
DK0533840T3
DK0533840T3 DK91912884.3T DK91912884T DK0533840T3 DK 0533840 T3 DK0533840 T3 DK 0533840T3 DK 91912884 T DK91912884 T DK 91912884T DK 0533840 T3 DK0533840 T3 DK 0533840T3
Authority
DK
Denmark
Prior art keywords
imidazole
angiotensin
renal failure
chronic renal
treatment
Prior art date
Application number
DK91912884.3T
Other languages
English (en)
Inventor
David John Carini
John Jonas Vytautas Duncia
Pancras Chor-Bun Wong
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Application granted granted Critical
Publication of DK0533840T3 publication Critical patent/DK0533840T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DK91912884.3T 1990-06-22 1991-06-07 Behandling af kronisk nyresvigt med imidazol-angiotensin-II-receptor-antagonister DK0533840T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54235190A 1990-06-22 1990-06-22

Publications (1)

Publication Number Publication Date
DK0533840T3 true DK0533840T3 (da) 1996-12-30

Family

ID=24163446

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91912884.3T DK0533840T3 (da) 1990-06-22 1991-06-07 Behandling af kronisk nyresvigt med imidazol-angiotensin-II-receptor-antagonister

Country Status (8)

Country Link
EP (1) EP0533840B1 (da)
JP (2) JPH05509086A (da)
AT (1) ATE146076T1 (da)
CA (1) CA2085584C (da)
DE (1) DE69123582T2 (da)
DK (1) DK0533840T3 (da)
GR (1) GR3022035T3 (da)
WO (1) WO1992000067A2 (da)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2058198A1 (en) * 1991-01-04 1992-07-05 Adalbert Wagner Azole derivatives, process for their preparation, and their use
JP3810020B2 (ja) * 1993-04-22 2006-08-16 武田薬品工業株式会社 腎疾患の予防または治療剤
FR2719598B1 (fr) * 1994-05-03 1996-07-26 Rhone Poulenc Chimie Composition élastomère silicone et ses applications, notamment pour l'enduction de sac gonflable, destiné à la protection d'un occupant de véhicule.
AU677702B2 (en) * 1994-10-13 1997-05-01 Takeda Pharmaceutical Company Limited A prophylactic or therapeutic drug for renal diseases
US6498142B1 (en) * 1996-05-06 2002-12-24 Curis, Inc. Morphogen treatment for chronic renal failure
ES2226125T3 (es) 1997-05-05 2005-03-16 Curis, Inc. Terapias para insuficiencia renal aguda.
SE9903028D0 (sv) 1999-08-27 1999-08-27 Astra Ab New use
WO2002064136A2 (en) 2001-01-26 2002-08-22 Chugai Seiyaku Kabushiki Kaisha Malonyl-coa decarboxylase inhibitors useful as metabolic modulators
ATE359773T1 (de) 2001-01-26 2007-05-15 Chugai Pharmaceutical Co Ltd Verfahren zur behandlung von erkrankungen mit malonyl coa-decarboxylase-inhibitoren
CN101596191B (zh) 2001-01-26 2011-06-15 中外制药株式会社 用作代谢调节剂的丙二酰基辅酶a脱羧酶抑制剂
US7709510B2 (en) 2001-02-20 2010-05-04 Chugai Seiyaku Kabushiki Kaisha Azoles as malonyl-CoA decarboxylase inhibitors useful as metabolic modulators
EP1379243B1 (en) 2001-02-20 2009-09-09 Chugai Seiyaku Kabushiki Kaisha Methods for treating metabolic diseases using malonyl-coa decarboxylase inhibitors
CA2533747C (en) 2003-08-01 2012-11-13 Chugai Seiyaku Kabushiki Kaisha Heterocyclic compounds useful as malonyl-coa decarboxylase inhibitors
ATE407673T1 (de) 2003-08-01 2008-09-15 Chugai Pharmaceutical Co Ltd Azol-verbindungen auf cyanoguanidin-basis als malonyl-coa decarboxylase-hemmer
CA2533749C (en) 2003-08-01 2012-07-10 Chugai Seiyaku Kabushiki Kaisha Piperidine compounds useful as malonyl-coa decarboxylase inhibitors
US7285562B2 (en) 2003-08-01 2007-10-23 Chugai Seiyaku Kabushiki Kaisha Cyanoamide compounds useful as malonyl-CoA decarboxylase inhibitors
US8257797B2 (en) 2003-11-03 2012-09-04 Bluestar Silicones France Silicone composition and process that is useful for improving the tear strength and the combing strength of an inflatable bag for protecting an occupant of a vehicle
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2688161C (en) 2007-06-04 2020-10-20 Kunwar Shailubhai Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
EP2297113A1 (en) * 2008-04-29 2011-03-23 Theravance, Inc. Dual-acting antihypertensive agents
CA2726917C (en) 2008-06-04 2018-06-26 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
JPWO2011077712A1 (ja) * 2009-12-22 2013-05-02 興和株式会社 新規な１−（ビフェニル−４−イル−メチル）−１ｈ−イミダゾール誘導体及びこれを含有する医薬
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CN105764916B (zh) 2013-06-05 2021-05-18 博士医疗爱尔兰有限公司 鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
KR102538999B1 (ko) 2016-06-29 2023-05-31 유니버시떼 드 몬트리얼 비아릴메틸 헤테로사이클

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015651A (en) * 1988-01-07 1991-05-14 E. I. Du Pont De Nemours And Company Treatment of hypertension with 1,2,4-angiotensin II antagonists
DK0403159T3 (da) * 1989-06-14 2000-08-14 Smithkline Beecham Corp Imidazolylalkensyrer
CA2060656A1 (en) * 1989-06-30 1990-12-31 Robert John Ardecky Substituted imidazoles
CA2032289A1 (en) * 1989-12-29 1991-06-30 Joseph A. Finkelstein Substituted 5-(alkyl) carboxamide imidazoles

Also Published As

Publication number Publication date
JPH11228410A (ja) 1999-08-24
DE69123582T2 (de) 1997-05-15
CA2085584A1 (en) 1991-12-23
ATE146076T1 (de) 1996-12-15
WO1992000067A2 (en) 1992-01-09
DE69123582D1 (de) 1997-01-23
CA2085584C (en) 2003-02-11
GR3022035T3 (en) 1997-03-31
JPH05509086A (ja) 1993-12-16
WO1992000067A3 (en) 1993-05-27
EP0533840A1 (en) 1993-03-31
EP0533840B1 (en) 1996-12-11

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