DK0531212T3 - Fremgangsmåde til fremstilling af hydrocortison og mellemprodukter til brug ved fremgangsmåden - Google Patents

Fremgangsmåde til fremstilling af hydrocortison og mellemprodukter til brug ved fremgangsmåden

Info

Publication number: DK0531212T3
Authority: DK; Denmark
Prior art keywords: intermediates; hydrocortisone; preparing; preparing hydrocortisone; image
Prior art date: 1991-09-06

Application number

DK92402406.0T

Other languages

English (en)

Inventor

Francis Brion

Christian Diolez

Jean Buendia

Michel Vivat

Original Assignee

Roussel Uclaf

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-09-06

Filing date

1992-09-03

Publication date

1997-03-03

1992-09-03 Application filed by Roussel Uclaf filed Critical Roussel Uclaf

1997-03-03 Application granted granted Critical

1997-03-03 Publication of DK0531212T3 publication Critical patent/DK0531212T3/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/007—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 17 (20)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/005—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton spiro-condensed
- C07J33/007—Cyclic thioketals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Steroid Compounds (AREA)
Enzymes And Modification Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

DK92402406.0T 1991-09-06 1992-09-03 Fremgangsmåde til fremstilling af hydrocortison og mellemprodukter til brug ved fremgangsmåden DK0531212T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9111052A FR2681069B1 (fr)	1991-09-06	1991-09-06	Nouveau procede de preparation de l'hydrocortisone et nouveaux intermediaires.

Publications (1)

Publication Number	Publication Date
DK0531212T3 true DK0531212T3 (da)	1997-03-03

Family

ID=9416716

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK92402406.0T DK0531212T3 (da)	1991-09-06	1992-09-03	Fremgangsmåde til fremstilling af hydrocortison og mellemprodukter til brug ved fremgangsmåden

Country Status (20)

Country	Link
US (4)	US5260463A (da)
EP (1)	EP0531212B1 (da)
JP (1)	JP3466645B2 (da)
KR (1)	KR100220542B1 (da)
CN (1)	CN1035947C (da)
AT (1)	ATE131488T1 (da)
AU (1)	AU653841B2 (da)
CA (1)	CA2077625C (da)
DE (1)	DE69206721T2 (da)
DK (1)	DK0531212T3 (da)
ES (1)	ES2089449T3 (da)
FR (1)	FR2681069B1 (da)
GR (1)	GR3018402T3 (da)
HU (1)	HU212666B (da)
MX (1)	MX9205063A (da)
PL (5)	PL173589B1 (da)
RU (1)	RU2060257C1 (da)
TW (1)	TW269693B (da)
UA (1)	UA35556C2 (da)
ZA (1)	ZA925516B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2683530B1 (fr) *	1991-11-08	1994-01-21	Roussel Uclaf	Nouveau procede de preparation de derives 20-oxo 17 alpha, 21-dihydroxyles du pregnane et nouveaux intermediaires.
FR2691968B1 (fr) *	1992-06-04	1994-07-29	Roussel Uclaf	Nouveau procede de preparation d'un derive sterouide 11-ceto.
FR2719588B1 (fr) *	1994-05-03	1996-06-07	Roussel Uclaf	Nouveau procédé de préparation de la substance "S" et nouveaux intermédiaires.
FR2721927B1 (fr) *	1994-07-01	1996-08-09	Roussel Uclaf	Nouveau procede de preparation de derives steroides 20-oxo 17 alpha, 21-dihydroxyles et nouveaux intermediaires
US5929262A (en) *	1995-03-30	1999-07-27	The United States Of America As Represented By The Department Of Health And Human Services	Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates
US6528652B1 (en) *	1999-01-21	2003-03-04	Chronimed	Composition and device for detecting leukocytes in urine
US6348324B1 (en)	1999-01-21	2002-02-19	Hypoguard America Limited	Composition and device for detecting leukocytes in urine
US8990064B2 (en) *	2009-07-28	2015-03-24	Language Weaver, Inc.	Translating documents based on content

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2744110A (en) *	1954-04-22	1956-05-01	Searle & Co	3-ethylene mercaptole derivatives of progesterone
GB1089788A (en) *	1965-07-07	1967-11-08	Parke Davis & Co	Process for the production of steroidal lactone compounds and intermediates thereof
NL7607283A (nl) *	1975-07-23	1977-01-25	Merck & Co Inc	Werkwijze voor het bereiden van nieuwe pregnaansteroiden.
FR2344286A1 (fr) *	1976-03-16	1977-10-14	Roussel Uclaf	Nouveaux derives 17-spirosultines, les g-hydroxy acides correspondants, leur procede de preparation et leur application comme medicament
US5182381A (en) *	1982-03-01	1993-01-26	Roussel Ulcaf	Intermediates for 3-keto-19-nor-Δ4,9 -steroids
EP0123734A1 (en) *	1983-04-29	1984-11-07	Gist-Brocades N.V.	17-(Isocyano-sulfonylmethylene)-steroids, 17-(formamido-sulfonylmethylene)-steroids and their preparation
GB8721384D0 (en) *	1987-09-11	1987-10-21	Erba Farmitalia	17-substituted andro-sta-1 4-dien-3-one derivatives
JP2812397B2 (ja) *	1988-04-08	1998-10-22	ヘキストマリオンルーセル	９α−ヒドロキシ−１７−メチレンステロイド，その製造方法及びコルチコステロイドの製造方法

1991
- 1991-09-06 FR FR9111052A patent/FR2681069B1/fr not_active Expired - Fee Related
1992
- 1992-07-22 ZA ZA925516A patent/ZA925516B/xx unknown
- 1992-07-23 TW TW081105829A patent/TW269693B/zh not_active IP Right Cessation
- 1992-07-27 AU AU20570/92A patent/AU653841B2/en not_active Expired
- 1992-08-21 RU SU925052452A patent/RU2060257C1/ru active
- 1992-08-25 US US07/935,535 patent/US5260463A/en not_active Expired - Lifetime
- 1992-08-25 JP JP24713992A patent/JP3466645B2/ja not_active Expired - Lifetime
- 1992-09-03 ES ES92402406T patent/ES2089449T3/es not_active Expired - Lifetime
- 1992-09-03 DK DK92402406.0T patent/DK0531212T3/da active
- 1992-09-03 AT AT92402406T patent/ATE131488T1/de active
- 1992-09-03 DE DE69206721T patent/DE69206721T2/de not_active Expired - Lifetime
- 1992-09-03 MX MX9205063A patent/MX9205063A/es unknown
- 1992-09-03 EP EP92402406A patent/EP0531212B1/fr not_active Expired - Lifetime
- 1992-09-04 PL PL92315567A patent/PL173589B1/pl unknown
- 1992-09-04 CA CA002077625A patent/CA2077625C/fr not_active Expired - Lifetime
- 1992-09-04 HU HU9202851A patent/HU212666B/hu unknown
- 1992-09-04 PL PL92295836A patent/PL172040B1/pl unknown
- 1992-09-04 PL PL92315568A patent/PL172809B1/pl unknown
- 1992-09-04 PL PL92319638A patent/PL173272B1/pl unknown
- 1992-09-04 PL PL92315569A patent/PL172822B1/pl unknown
- 1992-09-05 KR KR1019920016242A patent/KR100220542B1/ko not_active IP Right Cessation
- 1992-09-05 CN CN92110286A patent/CN1035947C/zh not_active Expired - Lifetime
1993
- 1993-06-18 UA UA93002997A patent/UA35556C2/uk unknown
- 1993-08-12 US US08/105,742 patent/US5401840A/en not_active Expired - Lifetime
1994
- 1994-12-22 US US08/362,120 patent/US5502182A/en not_active Expired - Lifetime
1995
- 1995-10-02 US US08/538,027 patent/US5556962A/en not_active Expired - Lifetime
- 1995-12-14 GR GR950401070T patent/GR3018402T3/el unknown

Also Published As

Publication number	Publication date
RU2060257C1 (ru)	1996-05-20
JP3466645B2 (ja)	2003-11-17
DE69206721D1 (de)	1996-01-25
PL172809B1 (pl)	1997-11-28
JPH05194581A (ja)	1993-08-03
PL173272B1 (pl)	1998-02-27
EP0531212B1 (fr)	1995-12-13
MX9205063A (es)	1993-05-01
PL295836A1 (en)	1993-05-17
CA2077625A1 (fr)	1993-03-07
FR2681069A1 (fr)	1993-03-12
UA35556C2 (uk)	2001-04-16
EP0531212A2 (fr)	1993-03-10
TW269693B (da)	1996-02-01
PL172822B1 (en)	1997-11-28
GR3018402T3 (en)	1996-03-31
EP0531212A3 (en)	1993-05-26
US5260463A (en)	1993-11-09
ATE131488T1 (de)	1995-12-15
HU212666B (en)	1996-09-30
AU2057092A (en)	1993-03-11
PL172040B1 (pl)	1997-07-31
AU653841B2 (en)	1994-10-13
US5502182A (en)	1996-03-26
CN1035947C (zh)	1997-09-24
FR2681069B1 (fr)	1995-04-28
KR100220542B1 (ko)	1999-10-01
PL173589B1 (pl)	1998-03-31
HU9202851D0 (en)	1992-11-30
ES2089449T3 (es)	1996-10-01
HUT62598A (en)	1993-05-28
ZA925516B (en)	1993-07-22
DE69206721T2 (de)	1996-05-23
CN1070196A (zh)	1993-03-24
US5556962A (en)	1996-09-17
CA2077625C (fr)	2003-10-28
US5401840A (en)	1995-03-28
KR930006048A (ko)	1993-04-20

Publication	Publication Date	Title
GR3033987T3 (en)	2000-11-30	Nematicide agents.
DK164703C (da)	1992-12-21	Analogifremgangsmaade til fremstilling af kvaternaere 6,11-dihydro-dibenzo-oeb,eaa-thiepin-11-n-alkyl-norscopinethere og mellemprodukt til anvendelse ved denne fremgangsmaade
DK568989D0 (da)	1989-11-14	Fremgangsmaade til fremstilling af 3,5-dimethyl-4-methoxypyridin-derivater og mellemprodukter til brug ved fremgangsmaaden
DK0531212T3 (da)	1997-03-03	Fremgangsmåde til fremstilling af hydrocortison og mellemprodukter til brug ved fremgangsmåden
YU96291A (sh)	1994-06-10	Postupak za dobijanje supstituisanih piperidina i supstituisani piperidini
DK0565558T3 (da)	1995-03-06	Fremgangsmåde og mellemprodukter til fremstilling af azabicyclo(2.2.2)octan-3-iminer
NO924967L (no)	1993-01-19	Fremgangsmaate og anordning for fremstilling av beta kasein
DK0805806T3 (da)	2000-05-01	Fremgangsmåde til fremstilling af 4,10-diacetoxy-2alpha-benzoyloxy-5beta,20-epoxy-1,7beta-dihydroxy-9-oxotax-11-en-13alpha-
NO952752D0 (no)	1995-07-11	Fremgangsmåte og innretning for fremstilling av 1,2-dikloretan ved direkte klorering
DK27584D0 (da)	1984-01-20	(-)-antipoden af (e)-1-cyclohexyl-4,4-dimethyl-3-hydroxy-2-(1,2,4-triazol-1-yl)-pent-1-en,dens fremstilling og anvendelse
DK0507234T3 (da)	2001-10-08	Fremgangsmåde til isolering af celler, isolerede celler (DSM 6314 og DSM 6418) samt anvendelse af isolerede celler til fremstilling af polysaccharider
BR9204331A (pt)	1993-05-18	Processo de preparacao de um composto e compostos
SE8601344L (sv)	1986-03-21	Derivat av 11-desoxi-17alfa-hydroxikortikosteron
DK0582977T3 (da)	1996-12-16	Fremgangsmåde til fremstilling af 1,3-dialkyl-5-hydroxyoxindoler og etherderivater deraf
DE3160639D1 (en)	1983-08-25	Fluor-containing azomethines, preparation thereof and use thereof as intermediates
DK556289A (da)	1990-05-11	Kemisk proces til fremstilling af imidazoquinoxaliner og mellemprodukter til brug i processen
DK0555283T3 (da)	1995-07-03	Mellemprodukter ved fremstillingen af 4,5-difluoranthranilinsyre
GR78608B (da)	1984-09-27
DK0609244T3 (da)	1999-08-23	Fremgangsmåde til fremstilling af halogenerede hydroxyphenyleddikesyrer