DK0415296T4 - Nye højalkaliske proteaser - Google Patents

Nye højalkaliske proteaser

Info

Publication number: DK0415296T4
Authority: DK; Denmark
Prior art keywords: dna sequences; amino acids; alkaline proteases; alkaline; point mutation
Prior art date: 1989-08-31

Application number

DK90116322T

Other languages

English (en)

Other versions

DK0415296T3 (da

Inventor

Roman Vetter

Detlef Wilke

Andre Clippe

Wolfgang Aehle

Dietmar Schomburg

Antoine Amory

Original Assignee

Biotechnolog Forschung Gmbh

Genencor Internat Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-31

Filing date

1990-08-25

Publication date

2001-11-12

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25884604&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0415296(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-08-25 Application filed by Biotechnolog Forschung Gmbh, Genencor Internat Gmbh filed Critical Biotechnolog Forschung Gmbh

1996-11-18 Application granted granted Critical

1996-11-18 Publication of DK0415296T3 publication Critical patent/DK0415296T3/da

2001-11-12 Publication of DK0415296T4 publication Critical patent/DK0415296T4/da

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
- C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Chemical & Material Sciences (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Organic Chemistry (AREA)
General Engineering & Computer Science (AREA)
Biotechnology (AREA)
Molecular Biology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Plant Pathology (AREA)
Enzymes And Modification Thereof (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Detergent Compositions (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

DK90116322T 1989-08-31 1990-08-25 Nye højalkaliske proteaser DK0415296T4 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3928804		1989-08-31
DE4023458A DE4023458A1 (de)	1989-08-31	1990-07-24	Neue hochalkalische proteasen

Publications (2)

Publication Number	Publication Date
DK0415296T3 DK0415296T3 (da)	1996-11-18
DK0415296T4 true DK0415296T4 (da)	2001-11-12

Family

ID=25884604

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90116322T DK0415296T4 (da)	1989-08-31	1990-08-25	Nye højalkaliske proteaser

Country Status (7)

Country	Link
EP (1)	EP0415296B2 (da)
JP (1)	JPH03139277A (da)
KR (1)	KR100196785B1 (da)
AT (1)	ATE143689T1 (da)
DE (2)	DE4023458A1 (da)
DK (1)	DK0415296T4 (da)
ES (1)	ES2093624T5 (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5482849A (en) *	1990-12-21	1996-01-09	Novo Nordisk A/S	Subtilisin mutants
BR9107258A (pt) *	1990-12-21	1994-02-22	Novo Nordisk As	Protease mutante e processo compreendendo o tratamento de uma protease
DE4106525A1 (de) *	1991-03-01	1992-09-10	Solvay Enzymes Gmbh & Co Kg	Verfahren zur verbesserung der stabilitaet von hochalkalischen proteasen
DK58391D0 (da) *	1991-04-03	1991-04-03	Novo Nordisk As	Hidtil ukendte proteaser
EP0525610A3 (en) *	1991-07-27	1993-03-24	Solvay Enzymes Gmbh & Co. Kg	Process for increasing the stability of enzymes and stabilized enzymes
DE69223562T2 (de) *	1991-08-27	1998-06-04	Hoffmann La Roche	Verfahren und Reagenzien zum Nachweis von Hepatitis C
US5371198A (en) *	1991-12-16	1994-12-06	Novo Nordisk A/S	Method for protection of proteolysis-susceptible protein during protein production in a fluid medium
US5256557A (en) *	1991-12-27	1993-10-26	Solvay Enzymes, Inc.	Purified alkaline protease concentrate and method of preparation
US5623059A (en) *	1992-03-09	1997-04-22	Novo Nordisk A/S	Method for protection of proteolysis-susceptible protein during protein production in a fluid medium
DE69333463D1 (de) *	1992-05-18	2004-05-06	Genencor Int	Alkalische Proteasen produzierende Bakterien, und Verfahren zur Herstellung dieser alkalischen Proteasen
PT717778E (pt) *	1992-07-17	2008-01-16	Genencor Int	Serina proteases resistentes a alcalinidade elevada
DE4304161A1 (de) *	1993-02-12	1994-08-25	Solvay Enzymes Gmbh & Co Kg	Verbesserte hochalkalische Proteasen
DE4411223A1 (de) *	1994-03-31	1995-10-05	Solvay Enzymes Gmbh & Co Kg	Verwendung alkalischer Proteasen in gewerblichen Textilwaschverfahren
EP1791966B1 (en)	2004-09-10	2014-06-04	Novozymes North America, Inc.	Methods for preventing, removing, reducing, or disrupting biofilm
ES2625751T3 (es) *	2010-05-06	2017-07-20	The Procter & Gamble Company	Productos de consumo con variantes de proteasa
CN103080415B (zh)	2010-07-01	2016-08-10	诺维信公司	纸浆的漂白
US9856466B2 (en)	2011-05-05	2018-01-02	Danisco Us Inc.	Compositions and methods comprising serine protease variants
CN103764905A (zh)	2011-09-09	2014-04-30	诺维信公司	改进纸张材料的特性
CN104822830B (zh)	2012-10-03	2021-07-09	谷万达公司	内含肽修饰的蛋白酶、其制备方法和工业用途
EP2740840A1 (en)	2012-12-07	2014-06-11	Novozymes A/S	Improving drainage of paper pulp
WO2016007309A1 (en)	2014-07-07	2016-01-14	Novozymes A/S	Use of prehydrolysate liquor in engineered wood
EP4004279A1 (en)	2019-07-26	2022-06-01	Novozymes A/S	Enzymatic treatment of paper pulp
WO2021239950A1 (en)	2020-05-29	2021-12-02	Novozymes A/S	Method for controlling slime in a pulp or paper making process
EP4355868A1 (en)	2021-06-16	2024-04-24	Novozymes A/S	Method for controlling slime in a pulp or paper making process
WO2023225459A2 (en)	2022-05-14	2023-11-23	Novozymes A/S	Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3770587A (en) *	1971-02-09	1973-11-06	Pfizer	Chemically modified proteolytic enzymes
NZ208612A (en) *	1983-06-24	1991-09-25	Genentech Inc	Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations
FR2598430B1 (fr) *	1986-05-06	1990-02-02	Roussel Uclaf	Nouveaux vecteurs d'expression, leur procede d'obtention et leur application pour exprimer une proteine quelconque dans escherichia coli
DK6488D0 (da) *	1988-01-07	1988-01-07	Novo Industri As	Enzymer
CN1056187C (zh) *	1988-02-11	2000-09-06	金克克国际有限公司	新的蛋白水解酶及其在洗涤剂中的应用
DK316989D0 (da) *	1989-06-26	1989-06-26	Novo Nordisk As	Enzymer

1990
- 1990-07-24 DE DE4023458A patent/DE4023458A1/de not_active Withdrawn
- 1990-08-25 DK DK90116322T patent/DK0415296T4/da active
- 1990-08-25 EP EP90116322A patent/EP0415296B2/de not_active Expired - Lifetime
- 1990-08-25 AT AT90116322T patent/ATE143689T1/de active
- 1990-08-25 DE DE59010522T patent/DE59010522D1/de not_active Expired - Lifetime
- 1990-08-25 ES ES90116322T patent/ES2093624T5/es not_active Expired - Lifetime
- 1990-08-29 KR KR1019900013379A patent/KR100196785B1/ko not_active IP Right Cessation
- 1990-08-31 JP JP2228503A patent/JPH03139277A/ja active Pending

Also Published As

Publication number	Publication date
ES2093624T3 (es)	1997-01-01
EP0415296A3 (en)	1991-10-02
DE4023458A1 (de)	1991-03-07
EP0415296B2 (de)	2001-04-25
EP0415296B1 (de)	1996-10-02
ATE143689T1 (de)	1996-10-15
KR100196785B1 (ko)	1999-06-15
EP0415296A2 (de)	1991-03-06
DK0415296T3 (da)	1996-11-18
KR910004806A (ko)	1991-03-29
DE59010522D1 (de)	1996-11-07
ES2093624T5 (es)	2001-08-16
JPH03139277A (ja)	1991-06-13

Publication	Publication Date	Title
DK0415296T3 (da)	1996-11-18	Nye højalkaliske proteaser
JP4086207B2 (ja)	2008-05-14	ズブチリシン変異体
BG89942A (bg)	1993-12-24	Метод за получаване на протеолитични ензими
DE69635444D1 (de)	2005-12-22	Gereinigte coprinus laccasen und nukleinsäuren welche dafür kodieren
NO20050998D0 (no)	2005-02-24	DNA som koder for et biologisk aktivt fragment av baktericid/premeabilitetsokende protein fremgangsmate for fremstilling av dette, samt farmasoytisk preparat inneholdende dette
BR9007477A (pt)	1992-06-02	Protease de subtilisina mutante e processo para a determinacao ou selecao da(s)posicao(oes)e do(s)aminoacido(s)a remover,substituir ou inserir no lugar do(s)aminoacido(s)da enzima mae
ES2125224T3 (es)	1999-03-01	Mutantes de subtilisina.
ID27693A (id)	2001-04-26	RANGKAIAN-RANGKAIAN NUKLEOTIDA YANG MENGKODE GEN pck
EA200100419A1 (ru)	2001-10-22	Трансформационная система в области грибов гифомицетов-хозяев
KR930703438A (ko)	1993-11-30	pH의 범위에 걸쳐 낮은 분자전위의 변이도를 갖는 효소돌연변이체
ATE360696T1 (de)	2007-05-15	Interferon-ähnliches protein zcyto21
IL85020A0 (en)	1988-06-30	Pancreatic secretory trypsin inhibitor and variants thereof,process expression vector and recombinant host therefor and pharmaceutical compositions containing it
BR9104613A (pt)	1992-06-09	Protease,sequencia de dna,vetor de expressao,transformante,metodo de producao de protease
DK0870833T3 (da)	2002-01-07	Gener for ultrathermostabile proteaser
DK0574347T3 (da)	2004-01-26	Hidtil ukendt svampeprotease
ES2196019T3 (es)	2003-12-16	Proteasa fungica.
BG92653A (bg)	1993-12-24	Метод за получаване на мутантни протеази
AU665935B2 (en)	1996-01-25	Thrombolytic peptide, production thereof and thrombolytic agent
MX9401068A (es)	1994-08-31	Mejoras en proteasa muy alcalinas que presentan una secuencia de aminoacidos.
Vetter et al.	1995	Highly alkaline proteases
EP0945512A3 (en)	2002-01-16	Novel serine proteases
AU3524593A (en)	1993-05-27	Mutation of the rhinovirus system