DK0387231T3 - Hidtil ukendte inhibitorer for retroviral protease - Google Patents
Hidtil ukendte inhibitorer for retroviral proteaseInfo
- Publication number
- DK0387231T3 DK0387231T3 DK90870034.7T DK90870034T DK0387231T3 DK 0387231 T3 DK0387231 T3 DK 0387231T3 DK 90870034 T DK90870034 T DK 90870034T DK 0387231 T3 DK0387231 T3 DK 0387231T3
- Authority
- DK
- Denmark
- Prior art keywords
- novel inhibitors
- retroviral protease
- protease
- retroviral
- peptides
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16211—Human Immunodeficiency Virus, HIV concerning HIV gagpol
- C12N2740/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/320,742 US5342922A (en) | 1989-03-08 | 1989-03-08 | Inhibitors of retroviral protease |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0387231T3 true DK0387231T3 (da) | 1995-07-03 |
Family
ID=23247697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90870034.7T DK0387231T3 (da) | 1989-03-08 | 1990-03-07 | Hidtil ukendte inhibitorer for retroviral protease |
Country Status (6)
Country | Link |
---|---|
US (2) | US5342922A (da) |
EP (1) | EP0387231B1 (da) |
AT (1) | ATE120468T1 (da) |
DE (1) | DE69018113T2 (da) |
DK (1) | DK0387231T3 (da) |
ES (1) | ES2070309T3 (da) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5086165A (en) * | 1989-03-08 | 1992-02-04 | Washington University | Inhibitors of retroviral protease with a ketomethylene isosteric replaced amide bond |
US5212157A (en) * | 1989-06-06 | 1993-05-18 | Bio-Mega, Inc. | Enzyme inhibitors |
US6313094B1 (en) | 1990-12-11 | 2001-11-06 | Japan Energy Corporation | β-amino-α-hydroxycarboxylic acid derivatives and HIV protease inhibitors |
US5554728A (en) * | 1991-07-23 | 1996-09-10 | Nexstar Pharmaceuticals, Inc. | Lipid conjugates of therapeutic peptides and protease inhibitors |
US5888992A (en) | 1992-03-11 | 1999-03-30 | Narhex Limited | Polar substituted hydrocarbons |
BR9306058A (pt) | 1992-03-11 | 1997-11-18 | Narhex Ltd | Derivados de amina de hidrocarbonetos oxo- e hidroxi- substituidos |
US6071895A (en) | 1992-03-11 | 2000-06-06 | Narhex Limited | Polar-substituted hydrocarbons |
US5559256A (en) * | 1992-07-20 | 1996-09-24 | E. R. Squibb & Sons, Inc. | Aminediol protease inhibitors |
DE69414279T2 (de) * | 1993-02-09 | 1999-04-08 | Bayer Corp., Pittsburgh, Pa. | Sulfonamidaminomethylenderivate als Immunsuppressiva |
EP0610745A3 (en) * | 1993-02-09 | 1994-09-28 | Miles Inc | Novel aminomethylene derivatives as immunosuppressants. |
US5686469A (en) * | 1993-02-09 | 1997-11-11 | Miles Inc. | Aminomethylene derivaties as immunosuppressants |
DE4332395A1 (de) * | 1993-09-23 | 1995-04-13 | Horst Dr Lindhofer | Inhibitoren zur Hemmung der zymogenähnlichen Freispaltung der HIV-1 Protease |
IL111991A (en) * | 1994-01-28 | 2000-07-26 | Abbott Lab | Liquid pharmaceutical composition of HIV protease inhibitors in organic solvent |
DE4412174A1 (de) * | 1994-04-08 | 1995-10-19 | Schramm Wolfgang Prof Dr | Peptide, Verfahren zu ihrer Herstellung und ihre Verwendung |
US6222043B1 (en) | 1995-06-30 | 2001-04-24 | Japan Energy Corporation | Methods of preparing novel dipeptide compounds or pharmaceutically acceptable salts thereof |
CA2179935C (en) * | 1995-06-30 | 2010-09-07 | Ryohei Kato | Novel dipeptide compound or pharmaceutically acceptable salt thereof and medical use thereof |
JP3098401B2 (ja) * | 1995-07-12 | 2000-10-16 | 株式会社エルティーティー研究所 | 経鼻投与用製剤 |
US5872210A (en) * | 1995-10-05 | 1999-02-16 | The United States Of America As Represented By The Department Of Health And Human Services | Transframe peptide inhibitor of viral protease |
US5747526A (en) * | 1996-01-25 | 1998-05-05 | Hollinshead; Ariel C. | Anti-HIV /Aids Chemo(C)-, immuno(I)-, or ci-therapy using tur (or related compounds) and/or NVA (or EPV) |
JP3020141B2 (ja) * | 1996-10-07 | 2000-03-15 | 株式会社富士薬品 | 経鼻投与用製剤 |
EP0900566A4 (en) | 1996-12-27 | 2001-04-25 | Japan Energy Corp | NEW TRIPEPTIDE COMPOUNDS AND MEDICINES AGAINST AIDS |
EP1068568A4 (en) * | 1998-04-03 | 2004-10-27 | Triangle Pharmaceuticals Inc | SYSTEMS, METHODS, AND COMPUTER PROGRAM PRODUCTS TO GUIDE THE SELECTION OF THERAPEUTIC SCHEMES $ i () |
US7141593B1 (en) * | 1999-06-04 | 2006-11-28 | Abbott Laboratories | Pharmaceutical formulations |
US7447643B1 (en) | 2000-09-21 | 2008-11-04 | Theradoc.Com, Inc. | Systems and methods for communicating between a decision-support system and one or more mobile information devices |
US20060198800A1 (en) * | 2003-08-14 | 2006-09-07 | Natalie Dilallo | Skin care compositions including hexapeptide complexes and methods of their manufacture |
WO2005016364A1 (en) * | 2003-08-14 | 2005-02-24 | Guthy-Renker Corporation | Skin care composition including hexapeptide complexes and methods of their manufacture |
US20090291884A1 (en) * | 2006-11-02 | 2009-11-26 | Michael Agadjanyan | Proteins for use in diagnosing and treating infection and disease |
FR2959992A1 (fr) * | 2010-05-11 | 2011-11-18 | Univ Claude Bernard Lyon | Peptides a activite antiproteasique |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4880779A (en) * | 1987-07-31 | 1989-11-14 | Research Corporation Technologies, Inc. | Method of prevention or treatment of AIDS by inhibition of human immunodeficiency virus |
IL90872A0 (en) * | 1988-07-08 | 1990-02-09 | Smithkline Beckman Corp | Retroviral protease binding peptides |
-
1989
- 1989-03-08 US US07/320,742 patent/US5342922A/en not_active Expired - Fee Related
-
1990
- 1990-03-07 ES ES90870034T patent/ES2070309T3/es not_active Expired - Lifetime
- 1990-03-07 DK DK90870034.7T patent/DK0387231T3/da active
- 1990-03-07 AT AT90870034T patent/ATE120468T1/de not_active IP Right Cessation
- 1990-03-07 EP EP90870034A patent/EP0387231B1/en not_active Expired - Lifetime
- 1990-03-07 DE DE69018113T patent/DE69018113T2/de not_active Expired - Fee Related
-
1994
- 1994-01-07 US US08/179,052 patent/US6121417A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE120468T1 (de) | 1995-04-15 |
DE69018113D1 (de) | 1995-05-04 |
US6121417A (en) | 2000-09-19 |
ES2070309T3 (es) | 1995-06-01 |
DE69018113T2 (de) | 1995-09-28 |
EP0387231B1 (en) | 1995-03-29 |
US5342922A (en) | 1994-08-30 |
EP0387231A2 (en) | 1990-09-12 |
EP0387231A3 (en) | 1991-05-02 |
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