DE69931958D1 - Enzymatisches verfahren zur herstellung von aminosäure-derivaten mit hoher enantiomerenreinheit - Google Patents

Enzymatisches verfahren zur herstellung von aminosäure-derivaten mit hoher enantiomerenreinheit

Info

Publication number
DE69931958D1
DE69931958D1 DE69931958T DE69931958T DE69931958D1 DE 69931958 D1 DE69931958 D1 DE 69931958D1 DE 69931958 T DE69931958 T DE 69931958T DE 69931958 T DE69931958 T DE 69931958T DE 69931958 D1 DE69931958 D1 DE 69931958D1
Authority
DE
Germany
Prior art keywords
preparation
alkyl
aryl group
chosen
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69931958T
Other languages
English (en)
Other versions
DE69931958T2 (de
Inventor
Jan Quaedflieg
Theodorus Sonke
Fritz Wagner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM IP Assets BV
Original Assignee
DSM IP Assets BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by DSM IP Assets BV filed Critical DSM IP Assets BV
Publication of DE69931958D1 publication Critical patent/DE69931958D1/de
Application granted granted Critical
Publication of DE69931958T2 publication Critical patent/DE69931958T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
    • C12P41/007—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures by reactions involving acyl derivatives of racemic amines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69931958T 1998-12-22 1999-12-17 Enzymatisches verfahren zur herstellung von aminosäure-derivaten mit hoher enantiomerenreinheit Expired - Fee Related DE69931958T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP98204371 1998-12-22
EP98204371A EP1013769A1 (de) 1998-12-22 1998-12-22 Enzymatisches Verfahren zur Herstellung von Aminosäure-Derivaten mit hoher enantiomerenreinheit
PCT/NL1999/000783 WO2000037657A1 (en) 1998-12-22 1999-12-17 Process for the enzymatic preparation of amino acid derivatives with enhanced optical purity

Publications (2)

Publication Number Publication Date
DE69931958D1 true DE69931958D1 (de) 2006-07-27
DE69931958T2 DE69931958T2 (de) 2006-12-21

Family

ID=8234516

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69931958T Expired - Fee Related DE69931958T2 (de) 1998-12-22 1999-12-17 Enzymatisches verfahren zur herstellung von aminosäure-derivaten mit hoher enantiomerenreinheit

Country Status (7)

Country Link
US (2) US7018817B1 (de)
EP (2) EP1013769A1 (de)
JP (1) JP2002533086A (de)
AT (1) ATE330016T1 (de)
AU (1) AU1898100A (de)
DE (1) DE69931958T2 (de)
WO (1) WO2000037657A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003010130A1 (en) * 2001-07-24 2003-02-06 Pharmacore, Inc. Amino acid derivatives
JP4126921B2 (ja) 2002-02-15 2008-07-30 味の素株式会社 光学活性なβ−フェニルアラニン誘導体の製造方法
NI200300043A (es) 2002-03-28 2003-11-05 Warner Lambert Co AMINOACIDOS CON AFINIDAD POR LA PROTEINA a2DELTA.
MXPA06003396A (es) 2003-09-25 2006-06-08 Warner Lambert Co Profarmacos de aminoacidos con afinidad por la proteina a 2d.
WO2017079656A2 (en) 2015-11-04 2017-05-11 The Trustees Of The University Of Pennsylvania Artificial proteins and compositions and methods thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4745067A (en) * 1985-05-02 1988-05-17 Microbial Chemistry Research Foundation L-aminoacylases
AU7359198A (en) * 1997-05-01 1998-11-27 G.D. Searle & Co. Method and apparatus for preparation of chiral beta amino acids
US6617127B2 (en) * 1998-12-22 2003-09-09 Holland Sweetener Company, V.O.F. Synthesis and recovery of aspartame involving enzymatic deformylation step

Also Published As

Publication number Publication date
US7018817B1 (en) 2006-03-28
US20060127997A1 (en) 2006-06-15
AU1898100A (en) 2000-07-12
US7129059B2 (en) 2006-10-31
DE69931958T2 (de) 2006-12-21
JP2002533086A (ja) 2002-10-08
ATE330016T1 (de) 2006-07-15
EP1141333A1 (de) 2001-10-10
WO2000037657A1 (en) 2000-06-29
EP1013769A1 (de) 2000-06-28
EP1141333B1 (de) 2006-06-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee