DE69926704D1 - Ein verfahren zur herstellung von amlodipin benzolsulfonat - Google Patents

Ein verfahren zur herstellung von amlodipin benzolsulfonat

Info

Publication number
DE69926704D1
DE69926704D1 DE69926704T DE69926704T DE69926704D1 DE 69926704 D1 DE69926704 D1 DE 69926704D1 DE 69926704 T DE69926704 T DE 69926704T DE 69926704 T DE69926704 T DE 69926704T DE 69926704 D1 DE69926704 D1 DE 69926704D1
Authority
DE
Germany
Prior art keywords
benzenesulphonate
amlodipine
benzolsulfonate
amlodipin
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69926704T
Other languages
English (en)
Inventor
Marek Wlostowski
Maciej Wieczorek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Adamed Sp zoo
Original Assignee
Adamed Sp zoo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20071938&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69926704(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Adamed Sp zoo filed Critical Adamed Sp zoo
Application granted granted Critical
Publication of DE69926704D1 publication Critical patent/DE69926704D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE69926704T 1998-04-09 1999-04-08 Ein verfahren zur herstellung von amlodipin benzolsulfonat Expired - Lifetime DE69926704D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PL98325757A PL189666B1 (pl) 1998-04-09 1998-04-09 Sposób otrzymywania benzenosulfonianu amlodypiny
PCT/PL1999/000011 WO1999052873A1 (en) 1998-04-09 1999-04-08 A process for the preparation of amlodipine benzenesulphonate

Publications (1)

Publication Number Publication Date
DE69926704D1 true DE69926704D1 (de) 2005-09-22

Family

ID=20071938

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69926704T Expired - Lifetime DE69926704D1 (de) 1998-04-09 1999-04-08 Ein verfahren zur herstellung von amlodipin benzolsulfonat

Country Status (15)

Country Link
EP (1) EP0993447B1 (de)
KR (1) KR100323244B1 (de)
CN (1) CN1122023C (de)
AT (1) ATE302187T1 (de)
AU (1) AU3061399A (de)
CZ (1) CZ295311B6 (de)
DE (1) DE69926704D1 (de)
ES (1) ES2245823T3 (de)
HU (1) HUP0003300A3 (de)
PL (1) PL189666B1 (de)
PT (1) PT993447E (de)
RU (1) RU2177000C2 (de)
SK (1) SK282736B6 (de)
UA (1) UA57091C2 (de)
WO (1) WO1999052873A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03005885A (es) * 2000-12-29 2005-04-19 Pfizer Ltd Procedimiento para fabricar maleato de amlodipina.
EP1309556B1 (de) 2000-12-29 2004-11-24 Pfizer Limited Amlodipinfumarat
CA2433284A1 (en) 2000-12-29 2002-07-11 Pfizer Limited Reference standards and processes for determining the purity or stability of amlodipine maleate
MXPA03005882A (es) 2000-12-29 2005-04-19 Pfizer Ltd Derivado amida de amlodipina.
GEP20063946B (en) * 2000-12-29 2006-10-25 Pfizer Ltd Process for making amlodipine maleate
CA2433191A1 (en) 2000-12-29 2002-07-11 Pfizer Limited Aspartate derivative of amlodipine as calcium channel antagonist
US7335380B2 (en) 2000-12-29 2008-02-26 Synthon Ip Inc. Amlodipine free base
AT5874U1 (de) 2000-12-29 2003-01-27 Bioorg Bv Pharmazeutische zubereitungen enthaltend amlodipinmaleat
US6653481B2 (en) 2000-12-29 2003-11-25 Synthon Bv Process for making amlodipine
BR0116554A (pt) 2000-12-29 2004-02-03 Pfizer Ltd Composto, composição farmacêutica para o tratamento da angina ou hipertensão, processo, processo para o tratamento ou prevenção da angina ou hipertensão, composição do ingrediente farmaceuticamente ativo e composição farmacêutica para o tratamento ou prevenção da angina ou hipertensão
ATE315026T1 (de) 2000-12-29 2006-02-15 Pfizer Ltd Amlodipin-hemimaleat
EP1221438B1 (de) * 2001-01-09 2007-03-14 Siegfried Generics International AG Salze von Amlodipin-Mesylat
EP1435954B1 (de) 2001-07-06 2010-01-13 LEK Pharmaceuticals D.D. Verfahren zur herstellung hochreines amlodipinbenzolsulfonat
US6680334B2 (en) 2001-08-28 2004-01-20 Pfizer Inc Crystalline material
AR037565A1 (es) * 2001-11-21 2004-11-17 Synthon Bv Formas de sales de amlodipina y procedimientos para prepararlas.
KR100538641B1 (ko) 2002-07-30 2005-12-22 씨제이 주식회사 암로디핀의 유기산염
KR100496436B1 (ko) 2002-07-30 2005-06-20 씨제이 주식회사 암로디핀의 유기산염
KR100462304B1 (ko) 2002-07-30 2004-12-17 씨제이 주식회사 암로디핀의 유기산염
KR100467669B1 (ko) 2002-08-21 2005-01-24 씨제이 주식회사 암로디핀의 유기산염
US6784297B2 (en) 2002-09-04 2004-08-31 Kopran Limited Process for the preparation of anti-ischemic and anti-hypertensive drug amlodipine besylate
AU2003253460A1 (en) * 2002-09-19 2004-04-08 Cj Corporation Crystalline organic acid salt of amlodipine
US20060035940A1 (en) * 2004-03-16 2006-02-16 Sepracor Inc. (S)-Amlodipine malate
CN100391946C (zh) * 2006-05-26 2008-06-04 苏州东瑞制药有限公司 一种苯磺酸氨氯地平的制备方法
PL236001B1 (pl) 2012-12-21 2020-11-30 Adamed Spolka Z Ograniczona Odpowiedzialnoscia Złożona kompozycja farmaceutyczna zawierająca kandesartan cyleksetylu oraz amlodypinę, sposób jej wytwarzania oraz jednostkowa postać dawkowania zawierająca tę kompozycję
CN103044314A (zh) * 2013-01-06 2013-04-17 先声药业有限公司 马来酸氨氯地平的制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8608335D0 (en) * 1986-04-04 1986-05-08 Pfizer Ltd Pharmaceutically acceptable salts

Also Published As

Publication number Publication date
AU3061399A (en) 1999-11-01
WO1999052873A1 (en) 1999-10-21
EP0993447A1 (de) 2000-04-19
HUP0003300A3 (en) 2002-11-28
CN1263525A (zh) 2000-08-16
PL325757A1 (en) 1999-10-11
KR100323244B1 (ko) 2002-02-19
SK169899A3 (en) 2000-06-12
CZ466999A3 (cs) 2000-04-12
CZ295311B6 (cs) 2005-07-13
CN1122023C (zh) 2003-09-24
SK282736B6 (sk) 2002-11-06
HUP0003300A2 (en) 2001-03-28
ES2245823T3 (es) 2006-01-16
UA57091C2 (uk) 2003-06-16
PT993447E (pt) 2005-10-31
RU2177000C2 (ru) 2001-12-20
ATE302187T1 (de) 2005-09-15
EP0993447B1 (de) 2005-08-17
PL189666B1 (pl) 2005-09-30
KR20010013297A (ko) 2001-02-26

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Legal Events

Date Code Title Description
8332 No legal effect for de