DE69925824D1 - Glutathionderivate und dazugehörige dosisformen - Google Patents

Glutathionderivate und dazugehörige dosisformen

Info

Publication number
DE69925824D1
DE69925824D1 DE69925824T DE69925824T DE69925824D1 DE 69925824 D1 DE69925824 D1 DE 69925824D1 DE 69925824 T DE69925824 T DE 69925824T DE 69925824 T DE69925824 T DE 69925824T DE 69925824 D1 DE69925824 D1 DE 69925824D1
Authority
DE
Germany
Prior art keywords
alkyl group
group
dosage forms
alkenyl group
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69925824T
Other languages
English (en)
Inventor
Kiyoyuki Sakon
Yoshimitsu Naniwa
Mitsuru Kobayashi
Daishiro Miura
Hiroshi Imai
Atsushi Imaizumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Application granted granted Critical
Publication of DE69925824D1 publication Critical patent/DE69925824D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
DE69925824T 1998-04-16 1999-04-16 Glutathionderivate und dazugehörige dosisformen Expired - Lifetime DE69925824D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10635998 1998-04-16
PCT/JP1999/002044 WO1999054346A1 (fr) 1998-04-16 1999-04-16 Derives du glutathione et leur forme posologique

Publications (1)

Publication Number Publication Date
DE69925824D1 true DE69925824D1 (de) 2005-07-21

Family

ID=14431564

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69925824T Expired - Lifetime DE69925824D1 (de) 1998-04-16 1999-04-16 Glutathionderivate und dazugehörige dosisformen

Country Status (10)

Country Link
US (2) US6627732B1 (de)
EP (1) EP1072608B1 (de)
JP (1) JP4059627B2 (de)
KR (1) KR20010042752A (de)
AT (1) ATE297945T1 (de)
AU (1) AU766515B2 (de)
CA (1) CA2328731A1 (de)
DE (1) DE69925824D1 (de)
TW (1) TW576838B (de)
WO (1) WO1999054346A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7029695B2 (en) 2001-07-10 2006-04-18 Telik, Inc. Therapeutic compositions containing glutathione analogs
US6747009B2 (en) * 2002-09-19 2004-06-08 Universiteit Leiden Peptidomimetic glutathione analogs
US8198247B2 (en) * 2004-12-21 2012-06-12 Telik, Inc. Process for and intermediates in the preparation of canfosfamide and its salts
TWI317738B (en) 2005-01-06 2009-12-01 Telik Inc Tripeptide and tetrapeptide thioethers
US7446096B2 (en) 2005-12-19 2008-11-04 Industrial Technology Research Institute Glutathione based delivery system
US8067380B2 (en) 2005-12-19 2011-11-29 Industrial Technology Research Institute Glutathione-based delivery system
TW200843786A (en) * 2007-03-20 2008-11-16 Univ Osaka Prophylactic and/or therapeutic agent for cardiac infarction
ES2322121B1 (es) * 2007-12-10 2010-04-19 Consejo Superior De Investigaciones Cientificas Nuevos derivados de aminoacidos dicarboxilicos y su aplicacion en el tratamiento de enfermedades neurodegenerativas.
US20110160144A1 (en) * 2009-12-28 2011-06-30 Perricone Nicholas V Topical Acyl Glutathione Formulations
US8580742B2 (en) * 2010-03-05 2013-11-12 N.V. Perricone Llc Topical glutathione formulations for menopausal skin
US8609604B2 (en) 2009-12-28 2013-12-17 N.V. Perricone Llc Methods of improving the appearance of aging skin
JP2013528213A (ja) * 2010-06-07 2013-07-08 テリック，インコーポレイテッド エザチオスタットの錠剤製剤
JP2013528214A (ja) 2010-06-07 2013-07-08 テリック，インコーポレイテッド 結晶性エザチオスタット塩酸塩非溶媒和物ｄ型の調製
BR112013033072B1 (pt) 2011-06-21 2021-04-13 Nitto Denko Corporation Uso de um agente
US20140120157A1 (en) 2012-09-19 2014-05-01 Georgetown University Targeted liposomes
JP6340162B2 (ja) 2012-12-20 2018-06-06 日東電工株式会社 アポトーシス誘導剤
CN106573062B (zh) 2014-06-17 2020-08-25 日东电工株式会社 细胞凋亡诱导剂
US10264976B2 (en) 2014-12-26 2019-04-23 The University Of Akron Biocompatible flavonoid compounds for organelle and cell imaging
RU2692065C1 (ru) * 2018-04-05 2019-06-20 федеральное государственное автономное образовательное учреждение высшего образования "Казанский (Приволжский) федеральный университет" (ФГАОУ ВО КФУ) Глутатионаммониевые соли o,o-диорганилдитиофосфорных кислот, обладающие антиоксидантной и противоопухолевой активностью
JP2022512077A (ja) 2018-11-16 2022-02-02 日東電工株式会社 Ｒｎａ干渉送達製剤及び悪性腫瘍のための方法
US11419849B1 (en) 2019-02-06 2022-08-23 Kitt Bio, Inc. Methods and products for adverse effects of air travel, jet lag, or a change to a sleep wake timing cycle
US20220347125A1 (en) 2019-05-14 2022-11-03 Keio University Antitumor agent and compounding agent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995005863A1 (en) * 1993-08-27 1995-03-02 St. Paul Medical, Inc. Needleless iv medical delivery system
AU715524B2 (en) 1995-06-07 2000-02-03 Telik, Inc. Metabolic effects of certain glutathione analogs
WO1999037802A1 (en) * 1998-01-21 1999-07-29 Telik, Inc. Methods to identify myelostimulants
JP2002535359A (ja) 1999-01-27 2002-10-22 テリック，インコーポレイテッド グルタチオン類縁体を含有する治療用組成物

Also Published As

Publication number Publication date
EP1072608A1 (de) 2001-01-31
US20040018985A1 (en) 2004-01-29
AU3344599A (en) 1999-11-08
US6627732B1 (en) 2003-09-30
ATE297945T1 (de) 2005-07-15
EP1072608A4 (de) 2001-09-19
WO1999054346A1 (fr) 1999-10-28
CA2328731A1 (en) 1999-10-28
KR20010042752A (ko) 2001-05-25
AU766515B2 (en) 2003-10-16
JP4059627B2 (ja) 2008-03-12
EP1072608B1 (de) 2005-06-15
TW576838B (en) 2004-02-21

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Legal Events

Date Code Title Description
8332 No legal effect for de