DE69923795D1 - Verfahren zur Herstellung biologisch-abbaubarer Polyester - Google Patents
Verfahren zur Herstellung biologisch-abbaubarer PolyesterInfo
- Publication number
- DE69923795D1 DE69923795D1 DE69923795T DE69923795T DE69923795D1 DE 69923795 D1 DE69923795 D1 DE 69923795D1 DE 69923795 T DE69923795 T DE 69923795T DE 69923795 T DE69923795 T DE 69923795T DE 69923795 D1 DE69923795 D1 DE 69923795D1
- Authority
- DE
- Germany
- Prior art keywords
- carboxyl
- polymer
- omega
- protected carboxyl
- acid derivative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
- A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
- C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
- C08G63/08—Lactones or lactides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Inorganic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Preparation (AREA)
- Polyesters Or Polycarbonates (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
- Biological Depolymerization Polymers (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP35649798 | 1998-12-15 | ||
JP35649798 | 1998-12-15 | ||
PCT/JP1999/007013 WO2000035990A1 (fr) | 1998-12-15 | 1999-12-14 | Procede de production d'un polymere |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69923795D1 true DE69923795D1 (de) | 2005-03-24 |
DE69923795T2 DE69923795T2 (de) | 2006-03-16 |
Family
ID=18449318
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69923795T Expired - Lifetime DE69923795T2 (de) | 1998-12-15 | 1999-12-14 | Verfahren zur Herstellung biologisch-abbaubarer Polyester |
Country Status (11)
Country | Link |
---|---|
US (1) | US6756472B1 (de) |
EP (1) | EP1158014B1 (de) |
KR (1) | KR100584634B1 (de) |
CN (1) | CN1134479C (de) |
AT (1) | ATE289205T1 (de) |
AU (1) | AU1797800A (de) |
CA (1) | CA2355186C (de) |
DE (1) | DE69923795T2 (de) |
ES (1) | ES2234325T3 (de) |
PT (1) | PT1158014E (de) |
WO (1) | WO2000035990A1 (de) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2378714A1 (en) | 1999-07-15 | 2001-01-25 | Takeda Chemical Industries, Ltd. | Sustained release compositions, methods for producing the same and uses thereof |
CA2407472A1 (en) * | 2000-06-14 | 2002-10-23 | Takeda Chemical Industries, Ltd. | Sustained release compositions |
PT1693054T (pt) * | 2000-08-07 | 2016-07-07 | Takeda Pharmaceuticals Co | Polímero de ácido láctico e processo para a sua produção |
FR2821360B1 (fr) | 2001-02-27 | 2003-05-30 | Sod Conseils Rech Applic | Procede de preparation de polyesters avec des fonctions acides libres intracatenaires |
TWI332407B (en) | 2001-06-29 | 2010-11-01 | Takeda Chemical Industries Ltd | Controlled release composition and method of producting the same |
TWI225416B (en) * | 2001-06-29 | 2004-12-21 | Takeda Chemical Industries Ltd | Sustained-release composition and process for producing the same |
DE60327737D1 (de) * | 2002-01-22 | 2009-07-09 | Biomatera Inc | Verfahren zur trocknung von biologisch abbaubaren polymeren |
EP1923075B1 (de) * | 2004-08-13 | 2015-11-11 | Rutgers, The State University | Röntgendichte Polymerstents |
ES2791698T3 (es) | 2006-12-18 | 2020-11-05 | Takeda Pharmaceuticals Co | Composición de liberación sostenida y método para producir la misma |
US8282990B2 (en) * | 2007-04-19 | 2012-10-09 | Dong-A Pharmaceutical, Co., Ltd. | Method for preparing a biodegradable polymer microsphere containing a glucose-regulating peptide |
EP2508504B1 (de) * | 2009-12-01 | 2016-04-13 | Sumitomo Chemical Co., Ltd | Verfahren zur herstellung von cycloalkandicarbonsäuremonoestern |
CN103275312B (zh) * | 2013-05-16 | 2015-01-21 | 湘潭大学 | 含侧羟基或侧羧基官能团的聚丙交酯及其制备方法 |
US20160106804A1 (en) | 2014-10-15 | 2016-04-21 | Yuhua Li | Pharmaceutical composition with improved stability |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW333456B (en) * | 1992-12-07 | 1998-06-11 | Takeda Pharm Ind Co Ltd | A pharmaceutical composition of sustained-release preparation the invention relates to a pharmaceutical composition of sustained-release preparation which comprises a physiologically active peptide. |
CA2167920A1 (en) | 1993-07-23 | 1995-02-02 | Abraham J. Domb | Nonoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers |
EP0668073B1 (de) * | 1994-02-21 | 1999-04-14 | Takeda Chemical Industries, Ltd. | Polyester Matrix für eine pharmazeutische Zusammensetzung mit verzögerter Freigabe |
PT839525E (pt) | 1996-10-31 | 2004-10-29 | Takeda Chemical Industries Ltd | Preparacao de libertacao prolongada |
AU758596B2 (en) * | 1998-01-16 | 2003-03-27 | Takeda Pharmaceutical Company Limited | Sustained release compositions, process for producing the same and utilization thereof |
CA2378714A1 (en) * | 1999-07-15 | 2001-01-25 | Takeda Chemical Industries, Ltd. | Sustained release compositions, methods for producing the same and uses thereof |
-
1999
- 1999-12-14 AT AT99961296T patent/ATE289205T1/de active
- 1999-12-14 CA CA002355186A patent/CA2355186C/en not_active Expired - Fee Related
- 1999-12-14 KR KR1020017007507A patent/KR100584634B1/ko active IP Right Grant
- 1999-12-14 PT PT99961296T patent/PT1158014E/pt unknown
- 1999-12-14 DE DE69923795T patent/DE69923795T2/de not_active Expired - Lifetime
- 1999-12-14 ES ES99961296T patent/ES2234325T3/es not_active Expired - Lifetime
- 1999-12-14 AU AU17978/00A patent/AU1797800A/en not_active Abandoned
- 1999-12-14 US US09/857,943 patent/US6756472B1/en not_active Expired - Lifetime
- 1999-12-14 EP EP99961296A patent/EP1158014B1/de not_active Expired - Lifetime
- 1999-12-14 WO PCT/JP1999/007013 patent/WO2000035990A1/ja active IP Right Grant
- 1999-12-14 CN CNB99815914XA patent/CN1134479C/zh not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CA2355186A1 (en) | 2000-06-22 |
EP1158014B1 (de) | 2005-02-16 |
WO2000035990A1 (fr) | 2000-06-22 |
US6756472B1 (en) | 2004-06-29 |
ATE289205T1 (de) | 2005-03-15 |
PT1158014E (pt) | 2005-04-29 |
CN1134479C (zh) | 2004-01-14 |
ES2234325T3 (es) | 2005-06-16 |
DE69923795T2 (de) | 2006-03-16 |
EP1158014A1 (de) | 2001-11-28 |
KR100584634B1 (ko) | 2006-05-30 |
AU1797800A (en) | 2000-07-03 |
EP1158014A4 (de) | 2003-01-22 |
CN1334834A (zh) | 2002-02-06 |
CA2355186C (en) | 2008-03-18 |
KR20010082348A (ko) | 2001-08-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |