DE69832624D1 - Hefestämme zur herstellung von milchsäure - Google Patents

Hefestämme zur herstellung von milchsäure

Info

Publication number
DE69832624D1
DE69832624D1 DE69832624T DE69832624T DE69832624D1 DE 69832624 D1 DE69832624 D1 DE 69832624D1 DE 69832624 T DE69832624 T DE 69832624T DE 69832624 T DE69832624 T DE 69832624T DE 69832624 D1 DE69832624 D1 DE 69832624D1
Authority
DE
Germany
Prior art keywords
hefestamms
preparation
milky acid
acid
milky
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69832624T
Other languages
English (en)
Other versions
DE69832624T2 (de
Inventor
Danilo Porro
Michele Bianchi
Maria Ranzi
Laura Frontali
Marina Vai
Adrian Winkler
Lilia Alberghina
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Primary Products Ingredients Americas LLC
Original Assignee
Tate and Lyle Ingredients Americas LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tate and Lyle Ingredients Americas LLC filed Critical Tate and Lyle Ingredients Americas LLC
Publication of DE69832624D1 publication Critical patent/DE69832624D1/de
Application granted granted Critical
Publication of DE69832624T2 publication Critical patent/DE69832624T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004Oxidoreductases (1.)
    • C12N9/0006Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56Lactic acid
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Alcoholic Beverages (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69832624T 1997-09-12 1998-09-11 Hefestämme zur herstellung von milchsäure Expired - Fee Related DE69832624T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT97MI002080A IT1294728B1 (it) 1997-09-12 1997-09-12 Ceppi di lievito per la riproduzione di acido lattico
ITMI972080 1997-09-12
PCT/EP1998/005758 WO1999014335A1 (en) 1997-09-12 1998-09-11 Yeast strains for the production of lactic acid

Publications (2)

Publication Number Publication Date
DE69832624D1 true DE69832624D1 (de) 2006-01-05
DE69832624T2 DE69832624T2 (de) 2006-06-08

Family

ID=11377865

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69832624T Expired - Fee Related DE69832624T2 (de) 1997-09-12 1998-09-11 Hefestämme zur herstellung von milchsäure

Country Status (13)

Country Link
US (3) US6429006B1 (de)
EP (1) EP1012298B1 (de)
JP (1) JP2001516584A (de)
AT (1) ATE311460T1 (de)
AU (1) AU748462B2 (de)
BR (1) BR9812434A (de)
CA (1) CA2302434A1 (de)
DE (1) DE69832624T2 (de)
DK (1) DK1012298T3 (de)
ES (1) ES2252863T3 (de)
IT (1) IT1294728B1 (de)
SI (1) SI1012298T1 (de)
WO (1) WO1999014335A1 (de)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US20070031950A1 (en) * 1998-09-11 2007-02-08 Winkler Aaron A Production of D-lactic acid with yeast
KR20020048910A (ko) 1999-05-21 2002-06-24 카길 다우 엘엘씨 유기 생성물의 합성방법 및 재료
AUPQ137699A0 (en) * 1999-07-02 1999-07-22 University Of New England, The Control of acidosis
US6268189B1 (en) 2000-03-24 2001-07-31 The United States Of America As Represented By The Secretary Of Agriculture Fungal lactate dehydrogenase gene and constructs for the expression thereof
JP2002136293A (ja) * 2000-08-23 2002-05-14 Toray Ind Inc 微生物およびd−乳酸の製造方法
US7141410B2 (en) * 2000-11-22 2006-11-28 Natureworks Llc Methods and materials for the production of organic products in cells of Candida species
WO2003027280A1 (fr) * 2001-09-20 2003-04-03 Toyota Jidosha Kabushiki Kaisha Systeme de surexpression genique
JP2003093060A (ja) * 2001-09-20 2003-04-02 Toyota Motor Corp 耐酸性微生物を用いた有機酸及びアルコールの製造方法
JP2003259878A (ja) * 2002-03-11 2003-09-16 Toyota Central Res & Dev Lab Inc 乳酸脱水素酵素をコードするdnaおよびその利用
EP1484407B1 (de) * 2002-03-11 2011-10-26 Toyota Jidosha Kabushiki Kaisha Verfahren zur steuerung der ethanolproduktion und massenproduktion von milchsäure und transformant dafür
DE60315028T2 (de) * 2002-05-30 2008-04-10 NatureWorks LLC, Minnetonka Verfahren und materialien zur produktion von d-milchsäure in hefe
GB0222185D0 (en) * 2002-09-24 2002-10-30 Forinnova As Use
US20050014692A1 (en) * 2003-01-21 2005-01-20 Newgard Christopher B. Lactate dehydrogenase as a novel target and reagent for diabetes therapy
WO2004065552A2 (en) * 2003-01-21 2004-08-05 Duke University Cell-based therapies for diabetes mellitus and other glucose intolerant states
ES2426966T3 (es) 2003-05-02 2013-10-28 Cargill, Incorporated Especies de levadura genéticamente modificadas, y procesos de fermentación que emplean levaduras genéticamente modificadas
AU2004241394B2 (en) 2003-05-22 2008-05-22 Teijin Limited DNA coding for protein having D-lactic acid dehydrogenase activity and use thereof
JP4460876B2 (ja) * 2003-11-07 2010-05-12 株式会社豊田中央研究所 有機酸存在下におけるプロモーター及びその利用
US20050112737A1 (en) * 2003-11-20 2005-05-26 A. E. Staley Manufacturing Co. Lactic acid producing yeast
EP1756292B8 (de) 2004-03-31 2014-09-24 Cargill, Incorporated Verfahren zur vergärung von oligomere saccharide enthaltenden zuckern
JP2006006271A (ja) * 2004-06-29 2006-01-12 Toyota Central Res & Dev Lab Inc 乳酸生産酵母および乳酸生産方法
JP4806904B2 (ja) * 2004-07-09 2011-11-02 トヨタ自動車株式会社 乳酸生産方法
US20060234360A1 (en) * 2005-04-13 2006-10-19 Paola Branduardi Ascorbic acid production from D-glucose in yeast
MX2007015170A (es) 2005-06-02 2008-02-20 Cargill Inc Levadura modificada geneticamente de la especie issatchenkia orientalis y de especies muy relacionadas, y procesos de fermentacion que la utilizan.
DK2305826T3 (en) 2005-08-10 2016-06-27 Univ Florida Materials and methods for the efficient production of lactic acid
WO2007038130A2 (en) * 2005-09-22 2007-04-05 Tate & Lyle Ingredients Americas, Inc. Improved strains for the production of organic acids
AU2006300688B2 (en) * 2005-10-14 2012-07-19 Toray Industries, Inc. Yeast and method of producing L-lactic acid
WO2007117282A2 (en) 2005-11-23 2007-10-18 Natureworks Llc Lactic acid-producing yeast cells having nonfunctional l-or d-lactate: ferricytochrome c oxidoreductase gene
CN101442910A (zh) 2006-03-13 2009-05-27 卡吉尔公司 具有从磷酸二羟丙酮到甘油的途径被破坏的酵母细胞
JP5320692B2 (ja) * 2006-06-28 2013-10-23 東レ株式会社 酵母及びl−乳酸の製造方法
WO2008133665A2 (en) 2006-12-07 2008-11-06 Massachusetts Institute Of Technology Global transcription machinery engineering
WO2008080124A2 (en) * 2006-12-21 2008-07-03 Gevo, Inc. Butanol production by metabolically engineered yeast
JP2010115112A (ja) * 2007-02-28 2010-05-27 Neo-Morgan Laboratory Inc 酵母の製造方法,酵母,及び乳酸の製造方法
JP2008283917A (ja) * 2007-05-18 2008-11-27 Toray Ind Inc 乳酸の製造方法
EP2158323A4 (de) * 2007-05-18 2011-06-22 Microbia Prec Engineering Inc Produktion organischer säure durch pilzzellen
US8859260B2 (en) 2007-12-07 2014-10-14 Toray Industries, Inc. Expression cassette for lactase dehydrogenase, transformed yeast and method of producing lactic acid
MX2010006679A (es) 2007-12-17 2010-11-30 Univ Amsterdam Reduccion de co2 inducida con luz para compuestos orgánicos que sirven como combustibles o como semiproductos industriales por un autotrofo que contiene un casete genico fermentador.
US8455239B2 (en) 2007-12-23 2013-06-04 Gevo, Inc. Yeast organism producing isobutanol at a high yield
ES2563040T3 (es) 2007-12-23 2016-03-10 Gevo, Inc. Organismo de levadura que produce isobutanol a un alto rendimiento
JP2011514140A (ja) 2007-12-27 2011-05-06 ジーヴォ,インコーポレイテッド 低濃度水溶液からの高級アルコールの回収
KR101483470B1 (ko) * 2008-02-04 2015-01-16 도레이 카부시키가이샤 연속 발효에 의한 유산의 제조방법
WO2009111513A1 (en) * 2008-03-03 2009-09-11 Joule Biotechnologies, Inc. Engineered co2 fixing microorganisms producing carbon-based products of interest
US8048654B2 (en) * 2010-06-09 2011-11-01 Joule Unlimited Technologies, Inc. Methods and compositions for the recombinant biosynthesis of fatty acids and esters
JP4963488B2 (ja) * 2008-04-23 2012-06-27 トヨタ自動車株式会社 変異体酵母及びこれを用いた物質生産方法
EP2128262A1 (de) * 2008-05-28 2009-12-02 Università Degli Studi Di Milano - Bicocca Verbesserte Hefestämme zur Herstellung organischer Säure
BRPI0913906A2 (pt) * 2008-06-30 2016-11-01 Toyota Motor Co Ltd processo para produzir ácido orgânico
EP2998402A1 (de) 2008-10-17 2016-03-23 Joule Unlimited Technologies, Inc. Ethanolherstellung durch mikroorganismen
EP2239333A1 (de) 2009-04-07 2010-10-13 Sanovations B.V. Verfahren zur Gewinnung von organischen Säuren aus wässrigen Lösungen, die aus bioorganischen Materialien erhalten werden
JP5876822B2 (ja) * 2009-04-30 2016-03-02 ゲノマチカ, インク. 1,3−ブタンジオールの産生のための生物
WO2011011464A2 (en) * 2009-07-20 2011-01-27 Joule Unlimited, Inc. Constructs and methods for efficient transformation of micro-organisms for production of carbon-based products of interest
WO2011021629A1 (ja) * 2009-08-21 2011-02-24 旭硝子株式会社 形質転換体およびその製造方法、ならびに乳酸の製造方法
US20120220007A1 (en) 2009-09-04 2012-08-30 President And Fellows Of Harvard College Production of secreted bioproducts from photosynthetic microbes
CN107828671B (zh) 2010-11-22 2022-03-08 卡吉尔公司 用于生产3-羟基丙酸的组合物和方法
DK2643466T5 (da) 2010-11-22 2017-11-27 Cargill Inc Gærceller og fremgangsmåde til at omdanne acetaldehyd til ethanol
EP2668281A4 (de) 2011-01-25 2015-08-26 Cargill Inc Zusammensetzungen und verfahren zur succinatherstellung
CA2832587A1 (en) 2011-04-11 2012-10-18 Cargill, Incorporated Compositions and methods for increased ethanol production from biomass
WO2012147903A1 (ja) * 2011-04-28 2012-11-01 東レ株式会社 乳酸生産酵母変異株および乳酸の製造方法
CN102816706B (zh) * 2011-05-12 2013-08-21 江南大学 中国酱香型白酒生产中高产乙醇低产杂醇油的酵母cgmcc 4745的筛选与应用
FR2988733B1 (fr) * 2012-03-27 2016-02-05 Carbios Microorganisme recombinant
BR112015001601A2 (pt) 2012-07-25 2017-11-07 Bioamber Sas células de levedura tendo curso de tca redutor de piruvato em succinato e superexpressão de uma enzima transidrogenase nad(p)+ exógena
JP2015528312A (ja) * 2012-09-14 2015-09-28 ミリアント・コーポレイションMyriant Corporation 低pH条件下での発酵による有機酸の生産
EP2925873B1 (de) 2012-11-30 2017-07-12 Novozymes, Inc. Herstellung von 3-hydroxypropionsäure mittels rekombinanter hefen
US20150315615A1 (en) 2012-12-10 2015-11-05 Cargill, Incorporated Batch feed process for fermenting sugars
US9222110B2 (en) 2012-12-17 2015-12-29 South Dakota Board Of Regents Microorganism and method for lactic acid production
JP2014150800A (ja) * 2013-02-05 2014-08-25 Samsung Electronics Co Ltd 乳酸トランスポーターを高レベルに発現させる乳酸生産微生物、及びそれを利用した乳酸生産方法
EP3027733B1 (de) 2013-07-31 2018-09-12 Novozymes A/S Herstellung von 3-hydroxypropionsäure durch rekombinante hefen, in denen eine insekten aspartat 1-decarboxylase exprimiert wird
KR20150034867A (ko) * 2013-09-25 2015-04-06 삼성전자주식회사 세포질 내 피루베이트 풀이 강화된 효모 및 이를 이용한 피루베이트 기반 대사산물을 생산하는 방법
US9593350B2 (en) 2014-02-14 2017-03-14 Samsung Electronics Co., Ltd. Lactate dehydrogenase mutant, polynucleotide coding for the mutant, yeast cell including the polynucleotide, method of preparing the mutant, and method of producing the lactate using the same
KR101577134B1 (ko) * 2014-05-09 2015-12-14 씨제이제일제당 (주) 젖산 생산이 향상된 미생물 및 이를 이용하여 젖산을 생산하는 방법
LT3143075T (lt) 2014-05-16 2022-09-12 Carbios Mišrių pet plastiko gaminių perdirbimo būdas
KR102227975B1 (ko) * 2014-07-24 2021-03-15 삼성전자주식회사 방사선 감수성 보완 키나아제의 활성이 증가되도록 유전적으로 조작된, 내산성을 갖는 효모 세포 및 그를 이용하여 락테이트를 생산하는 방법
KR102245298B1 (ko) * 2014-09-05 2021-04-27 삼성전자주식회사 증가된 edc 활성을 갖고 락테이트 생산능을 갖는 유전적으로 조작된 효모 세포, 그를 제조하는 방법, 그를 제조하는 방법, 및 그를 사용하여 락테이트를 생산하는 방법
WO2016062695A1 (en) 2014-10-21 2016-04-28 Carbios Polypeptide having a polyester degrading activity and uses thereof
EP3233995B1 (de) 2014-12-19 2023-08-09 Carbios Kunststoffzusammensetzung und herstellungsverfahren
CN107532153A (zh) 2015-03-13 2018-01-02 卡比奥斯公司 具有聚酯降解活性的新多肽及其用途
EP3274461A1 (de) 2015-03-27 2018-01-31 Cargill, Incorporated Glucoamylase-modifizierte hefestämme und verfahren zur bioproduktherstellung
US20180179499A1 (en) 2015-06-04 2018-06-28 Bioamber Inc. Biobased production of functionalized alpha-substituted acrylates and c4-dicarboxylates
CA2987705A1 (en) 2015-06-12 2016-12-15 Carbios Masterbatch composition comprising a high concentration of biological entities
WO2016199966A1 (ko) 2015-06-12 2016-12-15 씨제이제일제당 주식회사 젖산 생산이 향상된 미생물 및 이를 이용하여 젖산을 생산하는 방법
AU2016301365A1 (en) 2015-08-05 2018-03-08 Cargill, Incorporated Xylose isomerase-modified yeast strains and methods for bioproduct production
AU2016361425B2 (en) 2015-11-24 2021-04-01 Cargill Incorporated Genetically modified yeasts and fermentation processes using genetically modified yeasts
EP3394264A1 (de) 2015-12-21 2018-10-31 Carbios Polymilchsäure produzierende rekombinante hefezellen und verwendungen davon
US10947571B2 (en) * 2016-04-18 2021-03-16 Syconium Lactic Acid Gmbh Method for producing lactic acid in recombinant yeast cell culture
CN116199935A (zh) 2016-05-19 2023-06-02 卡比奥斯公司 一种降解塑料产品的方法
CN109661403A (zh) 2016-08-05 2019-04-19 嘉吉公司 前导序列修饰的葡糖淀粉酶多肽和具有增强的生物产物产生的工程化的酵母菌株
US11718820B2 (en) 2017-08-17 2023-08-08 Cargill, Incorporated Genetically modified haploid Issatchenkia orientalis
EP3752627A4 (de) * 2018-02-16 2021-12-22 PTT Global Chemical Public Company Limited Mikroorganismen und verfahren zur herstellung von milchsäure
KR102140596B1 (ko) 2018-04-17 2020-08-04 에스케이이노베이션 주식회사 유기산 내성 효모 유래 신규 프로모터 및 이를 이용한 목적유전자의 발현방법
KR102140597B1 (ko) 2018-04-17 2020-08-03 에스케이이노베이션 주식회사 에탄올 생산 경로가 억제된 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20200040017A (ko) * 2018-10-08 2020-04-17 에스케이이노베이션 주식회사 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20210041903A (ko) 2019-10-08 2021-04-16 에스케이이노베이션 주식회사 락테이트 대사 및 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법
KR20210158676A (ko) 2020-06-24 2021-12-31 에스케이이노베이션 주식회사 젖산 생산능이 증가된 재조합 내산성 효모

Family Cites Families (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2024565A (en) 1931-10-29 1935-12-17 Standard Brands Inc Process for the production of lactic acid
JPH0740945B2 (ja) * 1987-04-15 1995-05-10 東レ株式会社 発酵法によるピルビン酸の製造法
US4885247A (en) 1988-04-19 1989-12-05 Michigan Biotechnology Institute Recovery and purification of lactate salts from whole fermentation broth by electrodialysis
US5068418A (en) 1989-05-08 1991-11-26 Uop Separation of lactic acid from fermentation broth with an anionic polymeric absorbent
US5464760A (en) 1990-04-04 1995-11-07 University Of Chicago Fermentation and recovery process for lactic acid production
TW211560B (de) 1991-03-14 1993-08-21 Peilly Ind Inc
FR2692591B1 (fr) 1992-06-23 1995-06-09 Agronomique Inst Nat Rech Souches de levure exprimant le gene de la ldh lactique, et vecteurs utilisables pour l'obtention desdites souches.
FR2693463B1 (fr) * 1992-07-08 1994-09-02 Rhone Poulenc Rorer Sa Promoteur de levure et son utilisation.
AT398982B (de) 1993-02-18 1995-02-27 Vogelbusch Gmbh Verfahren zur abtrennung und reinigung von milchsäure
US6187951B1 (en) 1993-06-29 2001-02-13 Cargill, Incorporated Lactic acid production, separation and/or recovery process
US5510526A (en) 1993-06-29 1996-04-23 Cargill, Incorporated Lactic acid production, separation and/or recovery process
US6001255A (en) 1993-07-12 1999-12-14 Eyal; Aharon Process for the production of water-soluble salts of carboxylic and amino acids
US5503750A (en) 1993-10-04 1996-04-02 Russo, Jr.; Lawrence J. Membrane-based process for the recovery of lactic acid by fermentation of carbohydrate substrates containing sugars
US5573180A (en) * 1995-08-03 1996-11-12 Carrier Corporation Protective thermostat
DE19544233A1 (de) * 1995-11-28 1997-06-05 Hoechst Ag Verfahren zur Nutzung des Hefe-ADH II-Promotorsystems zur biotechnologischen Produktion heterologer Proteine in hohen Ausbeuten
IL119389A (en) 1996-10-09 2001-10-31 Cargill Inc Process for the recovery of lactic acid by liquid-liquid extraction using a cation exchanger
US6160173A (en) 1996-10-09 2000-12-12 Cargill Incorporated Process for the recovery of lactic acid esters and amides from aqueous solutions of lactic acid and/or salts thereof
NZ336852A (en) 1996-12-23 2000-06-23 Lactascan Aps Production of lactic acid from whey proteins where electrodialysis causes less biofouling of the electrodialysis membrane
BE1011197A3 (fr) 1997-06-06 1999-06-01 Brussels Biotech En Abrege Bb Procede de purification d'acide lactique.
IL121207A (en) 1997-06-30 2000-10-31 Staley Mfg Co A E Liquid-liquid extraction for the recovery of lactic acid with an amine solution in the presence of carbon dioxide
IT1294728B1 (it) 1997-09-12 1999-04-12 Biopolo S C A R L Ceppi di lievito per la riproduzione di acido lattico
US6229046B1 (en) 1997-10-14 2001-05-08 Cargill, Incorported Lactic acid processing methods arrangements and products
US6475759B1 (en) * 1997-10-14 2002-11-05 Cargill, Inc. Low PH lactic acid fermentation
US6043072A (en) * 1998-11-05 2000-03-28 Washington State University Research Foundation Nucleic acids encoding Taxus geranylgeranyl diphosphate synthase, and methods of use
KR20020048910A (ko) 1999-05-21 2002-06-24 카길 다우 엘엘씨 유기 생성물의 합성방법 및 재료
US20020102672A1 (en) 1999-10-04 2002-08-01 Joseph Mizrahi Process for producing a purified lactic acid solution
FR2799754A1 (fr) 1999-10-18 2001-04-20 Roquette Freres Procede de separation et de purification d'acide lactique a partir d'un milieu de fermentation
US6268189B1 (en) 2000-03-24 2001-07-31 The United States Of America As Represented By The Secretary Of Agriculture Fungal lactate dehydrogenase gene and constructs for the expression thereof
US7141410B2 (en) * 2000-11-22 2006-11-28 Natureworks Llc Methods and materials for the production of organic products in cells of Candida species
EP1339852A2 (de) 2000-11-22 2003-09-03 Cargill Dow LLC Methode und materiale für das synthese von organische produkte
EP1419108B1 (de) 2001-08-24 2005-12-21 Purac Biochem B.V. Verfahren zur herstellung von milchsäure und calciumsulfatdihydrat
AU2002311989A1 (en) 2001-11-23 2003-06-23 Cargill Dow Polymers Llc Methods and materials for the production of organic products in cells of $i(candida) species
EP1484407B1 (de) 2002-03-11 2011-10-26 Toyota Jidosha Kabushiki Kaisha Verfahren zur steuerung der ethanolproduktion und massenproduktion von milchsäure und transformant dafür
JP2003259878A (ja) 2002-03-11 2003-09-16 Toyota Central Res & Dev Lab Inc 乳酸脱水素酵素をコードするdnaおよびその利用
EP1504109B2 (de) 2002-05-14 2011-05-18 PURAC Biochem BV Verfahren zur herstellung von milchsäure oder deren salz durch gleichzeitige verzuckerung und fermentation von stärke
DE60315028T2 (de) 2002-05-30 2008-04-10 NatureWorks LLC, Minnetonka Verfahren und materialien zur produktion von d-milchsäure in hefe
BE1015060A3 (fr) 2002-08-06 2004-09-07 Brussels Biotech Nv Sa Procede de production de polylactide au depart d'une solution d'acide lactique ou d'un de ses derives.
EP1437415A1 (de) 2003-01-13 2004-07-14 PURAC Biochem BV Herstellung von Milchsäure aus einem pentose-enthaltenden Substrat
ES2426966T3 (es) 2003-05-02 2013-10-28 Cargill, Incorporated Especies de levadura genéticamente modificadas, y procesos de fermentación que emplean levaduras genéticamente modificadas
US7405068B2 (en) * 2003-05-02 2008-07-29 Tate & Lyle Ingredients Americas, Inc. Pyruvate producing yeast strain
AU2004241394B2 (en) 2003-05-22 2008-05-22 Teijin Limited DNA coding for protein having D-lactic acid dehydrogenase activity and use thereof
BRPI0414673B1 (pt) 2003-09-30 2019-12-17 Mitsui Chemicals Inc escherichia coli recombinante, bem como método para a produção de ácido d-láctico
US20050112737A1 (en) * 2003-11-20 2005-05-26 A. E. Staley Manufacturing Co. Lactic acid producing yeast
KR100517065B1 (ko) 2003-12-11 2005-09-26 씨제이 주식회사 고농도 고수율의 젖산을 생산하는 젖산균과 이를 이용한 젖산 생산방법
JP4494399B2 (ja) 2004-03-31 2010-06-30 三菱化学フーズ株式会社 L‐乳酸の製造方法
JP4954873B2 (ja) 2004-06-17 2012-06-20 ピュラック・バイオケム・ベスローテン・ベンノートシャップ 乳酸マグネシウム含有媒質からの乳酸または乳酸塩の調製方法

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US6429006B1 (en) 2002-08-06
US7049108B2 (en) 2006-05-23
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ATE311460T1 (de) 2005-12-15
EP1012298A1 (de) 2000-06-28
ITMI972080A1 (it) 1999-03-12
AU748462B2 (en) 2002-06-06
BR9812434A (pt) 2000-09-26
DK1012298T3 (da) 2006-04-10
US7326550B2 (en) 2008-02-05
IT1294728B1 (it) 1999-04-12
AU9539298A (en) 1999-04-05
CA2302434A1 (en) 1999-03-25
ES2252863T3 (es) 2006-05-16

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