DE69831421D1 - Zusammensetzungen zur nasalen verabreichung - Google Patents

Zusammensetzungen zur nasalen verabreichung

Info

Publication number
DE69831421D1
DE69831421D1 DE69831421T DE69831421T DE69831421D1 DE 69831421 D1 DE69831421 D1 DE 69831421D1 DE 69831421 T DE69831421 T DE 69831421T DE 69831421 T DE69831421 T DE 69831421T DE 69831421 D1 DE69831421 D1 DE 69831421D1
Authority
DE
Germany
Prior art keywords
compositions
nasal administration
nasal
administration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69831421T
Other languages
English (en)
Other versions
DE69831421T2 (de
Inventor
Lisbeth Illum
James Watts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyowa Kirin Services Ltd
Original Assignee
Archimedes Development Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9725519.4A external-priority patent/GB9725519D0/en
Priority claimed from GBGB9805253.3A external-priority patent/GB9805253D0/en
Application filed by Archimedes Development Ltd filed Critical Archimedes Development Ltd
Application granted granted Critical
Publication of DE69831421D1 publication Critical patent/DE69831421D1/de
Publication of DE69831421T2 publication Critical patent/DE69831421T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0043Nose
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Otolaryngology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Psychology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69831421T 1997-12-02 1998-11-27 Zusammensetzungen zur nasalen verabreichung Expired - Lifetime DE69831421T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9725519 1997-12-02
GBGB9725519.4A GB9725519D0 (en) 1997-12-02 1997-12-02 Nasal formulation
GB9805253 1998-03-13
GBGB9805253.3A GB9805253D0 (en) 1998-03-13 1998-03-13 Nasal formulation
PCT/GB1998/003572 WO1999027905A1 (en) 1997-12-02 1998-11-27 Compositions for nasal administration

Publications (2)

Publication Number Publication Date
DE69831421D1 true DE69831421D1 (de) 2005-10-06
DE69831421T2 DE69831421T2 (de) 2006-06-22

Family

ID=26312701

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69831421T Expired - Lifetime DE69831421T2 (de) 1997-12-02 1998-11-27 Zusammensetzungen zur nasalen verabreichung

Country Status (13)

Country Link
US (2) US6342251B1 (de)
EP (1) EP1035833B1 (de)
JP (2) JP4754067B2 (de)
AR (1) AR017694A1 (de)
AT (1) ATE303131T1 (de)
AU (1) AU751182B2 (de)
CA (1) CA2312839C (de)
DE (1) DE69831421T2 (de)
DK (1) DK1035833T3 (de)
ES (1) ES2249846T3 (de)
NO (1) NO329381B1 (de)
NZ (1) NZ504786A (de)
WO (1) WO1999027905A1 (de)

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US6200591B1 (en) 1998-06-25 2001-03-13 Anwar A. Hussain Method of administration of sildenafil to produce instantaneous response for the treatment of erectile dysfunction
DE19834507A1 (de) * 1998-07-31 2000-02-03 Hexal Ag Pharmazeutische, wasserlösliche Tablettenformulierung zur Anwendung von Sildenafil
DE19834506A1 (de) * 1998-07-31 2000-02-03 Hexal Ag Transmucosales therapeutisches System zur Anwendung von Sildenafil
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US7258850B2 (en) * 1999-05-04 2007-08-21 Aradigm Corporation Methods and compositions for treating erectile dysfunction
BR0005797A (pt) * 2000-03-20 2001-10-16 Abbott Lab Métodos para o tratamento de disfunção sexual com apomorfina em nìveis de concentração plasmática especificados
CN1471395A (zh) 2000-04-07 2004-01-28 ����ҽҩƷ���޹�˾ 阿扑***衍生物及其使用方法
JP2003534286A (ja) * 2000-05-26 2003-11-18 ホーファー リサーチ リミテッド ***障害症状改善のために、刺激物質の活性成分としてプロアントシアニジン、一酸化窒素源としてlアルギニン又はその塩の使用
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WO2004098647A2 (en) * 2003-04-30 2004-11-18 Nastech Pharmaceutical Company Inc. Claudins’ underexpression as markers of tumor metastasis
US20050090518A1 (en) * 2003-10-24 2005-04-28 Nastech Pharmaceutical Company Inc. Method for treating parkinson's disease using apomorphine and apomorphine prodrugs
US20050129679A1 (en) * 2003-12-15 2005-06-16 Nastech Pharmaceutical Company Inc. Method for opening tight junctions
US7297786B2 (en) * 2004-07-09 2007-11-20 University Of Iowa Research Foundation RNA interference in respiratory epitheial cells
US20070110788A1 (en) * 2005-11-14 2007-05-17 Hissong James B Injectable formulation capable of forming a drug-releasing device
US8846102B2 (en) * 2006-03-30 2014-09-30 Engene, Inc. Non-viral compositions and methods for transfecting gut cells in vivo
DK2014305T3 (en) 2006-04-21 2017-10-16 Toko Yakuhin Kogyo Kk SPRAYABLE GEL-SHAPED SKIN / MOSPHONE ADHESIVE AND ADMINISTRATIVE SYSTEM FOR USING THE PREPARATION
GB2437488A (en) * 2006-04-25 2007-10-31 Optinose As Pharmaceutical oily formulation for nasal or buccal administration
US20070264296A1 (en) * 2006-05-10 2007-11-15 Myntti Matthew F Biofilm extracellular polysachharide solvating system
US7993675B2 (en) * 2006-05-10 2011-08-09 Medtronic Xomed, Inc. Solvating system and sealant for medical use in the sinuses and nasal passages
US7976873B2 (en) * 2006-05-10 2011-07-12 Medtronic Xomed, Inc. Extracellular polysaccharide solvating system for treatment of bacterial ear conditions
US7959943B2 (en) * 2006-05-10 2011-06-14 Medtronics Xomed, Inc. Solvating system and sealant for medical use in the middle or inner ear
US8088095B2 (en) * 2007-02-08 2012-01-03 Medtronic Xomed, Inc. Polymeric sealant for medical use
GB0715285D0 (en) * 2007-08-06 2007-09-12 Britannia Pharmaceuticals Ltd Improvements in or relating to powdered medicaments for nasal delivery
WO2009040595A1 (en) * 2007-09-28 2009-04-02 Wockhardt Research Centre Multi-dose pharmaceutical composition of analgesic for nasal administration
GB0721394D0 (en) * 2007-10-31 2007-12-12 Vectura Group Plc Compositions for trating parkinson's disease
EP2057982A1 (de) 2007-11-09 2009-05-13 Archimedes Development Limited Intranasale Zusammensetzungen
CN106046396B (zh) 2008-04-24 2019-02-22 麦德托尼克公司 可再水化的多糖颗粒和海绵体
EP2291524A2 (de) 2008-04-24 2011-03-09 Medtronic, Inc Rehydratisierbare thiolierte polysaccharidpartikel und schwamm
WO2009132228A1 (en) 2008-04-24 2009-10-29 Medtronic, Inc. Chitosan-containing protective composition
EP2310002B1 (de) * 2008-04-24 2016-11-02 Medtronic, Inc Schutzgel auf basis von chitosan und oxidiertem polysaccharid
ES2759373T3 (es) 2008-06-12 2020-05-08 Medtronic Xomed Inc Producto para el tratamiento de heridas crónicas con un sistema extracelular de solvatación de sustancias poliméricas
WO2010042427A2 (en) 2008-10-06 2010-04-15 Microbial Defense Systems, Llc Antimicrobial composition and methods of making and using same
CZ302789B6 (cs) 2009-11-25 2011-11-09 Zentiva, K. S. Zpusob zvýšení rozpustnosti farmaceuticky aktivních látek a cílený (kontrolovaný) transport do streva
BR112013028673B1 (pt) 2011-05-10 2020-06-16 Next Science IP Holdings Pty Ltd Sólido antimicrobiano e métodos de fazer e usar o mesmo
CA2919198A1 (en) 2013-07-23 2015-01-29 Allergan, Inc. Methods and compositions comprising desmopressin in combination with a beta-3-adrenergic receptor agonist
US10598672B2 (en) 2014-02-18 2020-03-24 Cyrano Therapeutics, Inc. Methods and compositions for diagnosing and treating loss and/or distortion of taste or smell
KR20240010751A (ko) * 2014-11-20 2024-01-24 세레니티 파마슈티컬즈 엘엘씨 알파-아드레날린성 수용체 길항제와 조합된 데스모프레신을 포함하는 방법 및 조성물
FR3032618A1 (fr) * 2015-02-12 2016-08-19 Laboratoires Chemineau Composition a base de plantes de la famille des malvaceae pour une administration dans la cavite nasale
EP3056219B1 (de) * 2015-02-12 2018-08-22 Laboratoires Chemineau Zusammensetzung auf pflanzenbasis der familie der malvengewächse (malvaceae) zur verabreichung auf schleimhäuten
WO2017168174A1 (en) 2016-04-02 2017-10-05 N4 Pharma Uk Limited New pharmaceutical forms of sildenafil
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Also Published As

Publication number Publication date
US20010046519A1 (en) 2001-11-29
ES2249846T3 (es) 2006-04-01
US6342251B1 (en) 2002-01-29
EP1035833B1 (de) 2005-08-31
ATE303131T1 (de) 2005-09-15
DE69831421T2 (de) 2006-06-22
AR017694A1 (es) 2001-09-12
NO20002851D0 (no) 2000-06-02
WO1999027905A1 (en) 1999-06-10
JP2011026341A (ja) 2011-02-10
CA2312839A1 (en) 1999-06-10
JP2001524509A (ja) 2001-12-04
NZ504786A (en) 2005-07-29
AU751182B2 (en) 2002-08-08
NO20002851L (no) 2000-06-02
DK1035833T3 (da) 2006-01-09
EP1035833A1 (de) 2000-09-20
AU1253599A (en) 1999-06-16
CA2312839C (en) 2008-01-15
JP4754067B2 (ja) 2011-08-24
NO329381B1 (no) 2010-10-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: STROHSCHAENK UND KOLLEGEN, 85521 OTTOBRUNN