DE69823889D1 - Trennungsmethode unter verwendung von flüssig-flüssig partition - Google Patents

Trennungsmethode unter verwendung von flüssig-flüssig partition

Info

Publication number
DE69823889D1
DE69823889D1 DE69823889T DE69823889T DE69823889D1 DE 69823889 D1 DE69823889 D1 DE 69823889D1 DE 69823889 T DE69823889 T DE 69823889T DE 69823889 T DE69823889 T DE 69823889T DE 69823889 D1 DE69823889 D1 DE 69823889D1
Authority
DE
Germany
Prior art keywords
phase
liquid
polymer
compound
separation method
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69823889T
Other languages
English (en)
Inventor
Folke Tjerneld
Josefine Persson
Hans Olof Johansson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JOHANSSON HANS OLAF
Original Assignee
JOHANSSON HANS OLAF
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JOHANSSON HANS OLAF filed Critical JOHANSSON HANS OLAF
Application granted granted Critical
Publication of DE69823889D1 publication Critical patent/DE69823889D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/20Partition-, reverse-phase or hydrophobic interaction chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
DE69823889T 1998-12-30 1998-12-30 Trennungsmethode unter verwendung von flüssig-flüssig partition Expired - Lifetime DE69823889D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/SE1998/002469 WO2000040598A1 (en) 1998-12-30 1998-12-30 Separation method utilizing liquid-liquid partition

Publications (1)

Publication Number Publication Date
DE69823889D1 true DE69823889D1 (de) 2004-06-17

Family

ID=20412023

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69823889T Expired - Lifetime DE69823889D1 (de) 1998-12-30 1998-12-30 Trennungsmethode unter verwendung von flüssig-flüssig partition

Country Status (8)

Country Link
US (1) US6454950B1 (de)
EP (1) EP1159290B1 (de)
JP (1) JP2002538942A (de)
AT (1) ATE266672T1 (de)
AU (1) AU777203B2 (de)
CA (1) CA2356704A1 (de)
DE (1) DE69823889D1 (de)
WO (1) WO2000040598A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904803D0 (sv) * 1999-12-27 1999-12-27 Amersham Pharm Biotech Ab Method for the isolation of hydrophobic proteins
DE602005009827D1 (de) * 2004-06-29 2008-10-30 Ares Trading Sa Verfahren zur aufreinigung von il-18-bindendem protein
KR101482791B1 (ko) * 2005-03-11 2015-01-21 와이어쓰 엘엘씨 약한 분배성 크로마토그래피법
CA2632328A1 (en) * 2005-12-22 2007-06-28 Ge Healthcare Bio-Sciences Ab Preparation of biomolecules
US20080070230A1 (en) * 2006-06-12 2008-03-20 Wyeth Methods for reducing or preventing liquid-liquid phase separation in high concentration protein solutions
FR2902799B1 (fr) 2006-06-27 2012-10-26 Millipore Corp Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide
US8569464B2 (en) * 2006-12-21 2013-10-29 Emd Millipore Corporation Purification of proteins
US8163886B2 (en) * 2006-12-21 2012-04-24 Emd Millipore Corporation Purification of proteins
US8362217B2 (en) 2006-12-21 2013-01-29 Emd Millipore Corporation Purification of proteins
BRPI0812721A2 (pt) * 2007-06-19 2014-12-30 Ge Healthcare Bio Sciences Ab Processo para isolar um ou mais compostos alvo de um líquido aquoso, processo de multietapas para isolar um ou mais compostos alvo, e, método para isolar pelo menos um anticorpo de um líquido
DE102008013490A1 (de) * 2008-03-10 2009-09-17 Bayer Technology Services Gmbh Verfahren zur Reinigung therapeutischer Proteine
WO2009151514A1 (en) * 2008-06-11 2009-12-17 Millipore Corporation Stirred tank bioreactor
US20100190963A1 (en) * 2008-12-16 2010-07-29 Millipore Corporation Stirred Tank Reactor And Method
JP5785098B2 (ja) * 2009-01-08 2015-09-24 ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ 単一ポリマー相系を用いる分離方法
WO2011146394A1 (en) 2010-05-17 2011-11-24 Millipore Corporation Stimulus responsive polymers for the purification of biomolecules
US9176105B2 (en) 2010-08-20 2015-11-03 President And Fellows Of Harvard College Density-based separation of biological analytes using multiphase systems
EP2619580A4 (de) * 2010-09-24 2014-05-07 Univ Michigan Lösungs-mikroarrays und verwendungen davon
US20150316566A1 (en) 2014-05-02 2015-11-05 Cerenis Therapeutics Holding Sa Hdl therapy markers
US9678076B2 (en) * 2014-06-24 2017-06-13 Analiza, Inc. Methods and devices for determining a disease state
US10450345B2 (en) 2017-06-09 2019-10-22 General Electric Company Method of isolation of polypeptide-aptamer-polymer conjugates
CN110003323B (zh) * 2019-04-02 2021-01-01 武汉大学 一种双水相体系分离纯化蛋白质的方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6048715A (en) * 1988-07-08 2000-04-11 Univ. Of British Columbia Two-phase partition affinity separation system and affinity separated cell-containing composition
US5078886A (en) * 1989-10-18 1992-01-07 Lehigh University Separation of mixtures by two-phase systems
WO1997005480A1 (en) * 1995-07-27 1997-02-13 Massachusetts Institute Of Technology Separation and/or concentration of an analyte from a mixture using a two-phase aqueous micellar system
CA2265929A1 (en) 1996-09-11 1998-03-19 Pharmacia & Upjohn Ab A process for purifying apolipoproteins and a composition for use in the process

Also Published As

Publication number Publication date
AU777203B2 (en) 2004-10-07
ATE266672T1 (de) 2004-05-15
AU2646299A (en) 2000-07-24
EP1159290A1 (de) 2001-12-05
JP2002538942A (ja) 2002-11-19
EP1159290B1 (de) 2004-05-12
WO2000040598A1 (en) 2000-07-13
US6454950B1 (en) 2002-09-24
CA2356704A1 (en) 2000-07-13

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