DE69823889D1 - Trennungsmethode unter verwendung von flüssig-flüssig partition - Google Patents
Trennungsmethode unter verwendung von flüssig-flüssig partitionInfo
- Publication number
- DE69823889D1 DE69823889D1 DE69823889T DE69823889T DE69823889D1 DE 69823889 D1 DE69823889 D1 DE 69823889D1 DE 69823889 T DE69823889 T DE 69823889T DE 69823889 T DE69823889 T DE 69823889T DE 69823889 D1 DE69823889 D1 DE 69823889D1
- Authority
- DE
- Germany
- Prior art keywords
- phase
- liquid
- polymer
- compound
- separation method
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Extraction Or Liquid Replacement (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/SE1998/002469 WO2000040598A1 (en) | 1998-12-30 | 1998-12-30 | Separation method utilizing liquid-liquid partition |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69823889D1 true DE69823889D1 (de) | 2004-06-17 |
Family
ID=20412023
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69823889T Expired - Lifetime DE69823889D1 (de) | 1998-12-30 | 1998-12-30 | Trennungsmethode unter verwendung von flüssig-flüssig partition |
Country Status (8)
Country | Link |
---|---|
US (1) | US6454950B1 (de) |
EP (1) | EP1159290B1 (de) |
JP (1) | JP2002538942A (de) |
AT (1) | ATE266672T1 (de) |
AU (1) | AU777203B2 (de) |
CA (1) | CA2356704A1 (de) |
DE (1) | DE69823889D1 (de) |
WO (1) | WO2000040598A1 (de) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9904803D0 (sv) * | 1999-12-27 | 1999-12-27 | Amersham Pharm Biotech Ab | Method for the isolation of hydrophobic proteins |
DE602005009827D1 (de) * | 2004-06-29 | 2008-10-30 | Ares Trading Sa | Verfahren zur aufreinigung von il-18-bindendem protein |
KR101482791B1 (ko) * | 2005-03-11 | 2015-01-21 | 와이어쓰 엘엘씨 | 약한 분배성 크로마토그래피법 |
CA2632328A1 (en) * | 2005-12-22 | 2007-06-28 | Ge Healthcare Bio-Sciences Ab | Preparation of biomolecules |
US20080070230A1 (en) * | 2006-06-12 | 2008-03-20 | Wyeth | Methods for reducing or preventing liquid-liquid phase separation in high concentration protein solutions |
FR2902799B1 (fr) | 2006-06-27 | 2012-10-26 | Millipore Corp | Procede et unite de preparation d'un echantillon pour l'analyse microbiologique d'un liquide |
US8569464B2 (en) * | 2006-12-21 | 2013-10-29 | Emd Millipore Corporation | Purification of proteins |
US8163886B2 (en) * | 2006-12-21 | 2012-04-24 | Emd Millipore Corporation | Purification of proteins |
US8362217B2 (en) | 2006-12-21 | 2013-01-29 | Emd Millipore Corporation | Purification of proteins |
BRPI0812721A2 (pt) * | 2007-06-19 | 2014-12-30 | Ge Healthcare Bio Sciences Ab | Processo para isolar um ou mais compostos alvo de um líquido aquoso, processo de multietapas para isolar um ou mais compostos alvo, e, método para isolar pelo menos um anticorpo de um líquido |
DE102008013490A1 (de) * | 2008-03-10 | 2009-09-17 | Bayer Technology Services Gmbh | Verfahren zur Reinigung therapeutischer Proteine |
WO2009151514A1 (en) * | 2008-06-11 | 2009-12-17 | Millipore Corporation | Stirred tank bioreactor |
US20100190963A1 (en) * | 2008-12-16 | 2010-07-29 | Millipore Corporation | Stirred Tank Reactor And Method |
JP5785098B2 (ja) * | 2009-01-08 | 2015-09-24 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | 単一ポリマー相系を用いる分離方法 |
WO2011146394A1 (en) | 2010-05-17 | 2011-11-24 | Millipore Corporation | Stimulus responsive polymers for the purification of biomolecules |
US9176105B2 (en) | 2010-08-20 | 2015-11-03 | President And Fellows Of Harvard College | Density-based separation of biological analytes using multiphase systems |
EP2619580A4 (de) * | 2010-09-24 | 2014-05-07 | Univ Michigan | Lösungs-mikroarrays und verwendungen davon |
US20150316566A1 (en) | 2014-05-02 | 2015-11-05 | Cerenis Therapeutics Holding Sa | Hdl therapy markers |
US9678076B2 (en) * | 2014-06-24 | 2017-06-13 | Analiza, Inc. | Methods and devices for determining a disease state |
US10450345B2 (en) | 2017-06-09 | 2019-10-22 | General Electric Company | Method of isolation of polypeptide-aptamer-polymer conjugates |
CN110003323B (zh) * | 2019-04-02 | 2021-01-01 | 武汉大学 | 一种双水相体系分离纯化蛋白质的方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6048715A (en) * | 1988-07-08 | 2000-04-11 | Univ. Of British Columbia | Two-phase partition affinity separation system and affinity separated cell-containing composition |
US5078886A (en) * | 1989-10-18 | 1992-01-07 | Lehigh University | Separation of mixtures by two-phase systems |
WO1997005480A1 (en) * | 1995-07-27 | 1997-02-13 | Massachusetts Institute Of Technology | Separation and/or concentration of an analyte from a mixture using a two-phase aqueous micellar system |
CA2265929A1 (en) | 1996-09-11 | 1998-03-19 | Pharmacia & Upjohn Ab | A process for purifying apolipoproteins and a composition for use in the process |
-
1998
- 1998-12-30 AT AT98966937T patent/ATE266672T1/de not_active IP Right Cessation
- 1998-12-30 JP JP2000592306A patent/JP2002538942A/ja active Pending
- 1998-12-30 CA CA002356704A patent/CA2356704A1/en not_active Abandoned
- 1998-12-30 DE DE69823889T patent/DE69823889D1/de not_active Expired - Lifetime
- 1998-12-30 EP EP98966937A patent/EP1159290B1/de not_active Expired - Lifetime
- 1998-12-30 WO PCT/SE1998/002469 patent/WO2000040598A1/en active IP Right Grant
- 1998-12-30 US US09/869,657 patent/US6454950B1/en not_active Expired - Fee Related
- 1998-12-30 AU AU26462/99A patent/AU777203B2/en not_active Ceased
Also Published As
Publication number | Publication date |
---|---|
AU777203B2 (en) | 2004-10-07 |
ATE266672T1 (de) | 2004-05-15 |
AU2646299A (en) | 2000-07-24 |
EP1159290A1 (de) | 2001-12-05 |
JP2002538942A (ja) | 2002-11-19 |
EP1159290B1 (de) | 2004-05-12 |
WO2000040598A1 (en) | 2000-07-13 |
US6454950B1 (en) | 2002-09-24 |
CA2356704A1 (en) | 2000-07-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |