DE69818091D1 - Verfahren zur herstellung von derivaten von brommethyl-biphenyl verbindungen - Google Patents

Verfahren zur herstellung von derivaten von brommethyl-biphenyl verbindungen

Info

Publication number: DE69818091D1
Authority: DE; Germany
Prior art keywords: preparation; derivatives; brommethyl; biphenyl compounds; formula
Prior art date: 1997-11-17
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69818091T

Other languages

English (en)

Other versions

DE69818091T2 (de

Inventor

Michel Biard

Bertrand Castro

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Sanofi Aventis France

Original Assignee

Sanofi Synthelabo SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-11-17

Filing date

1998-11-09

Publication date

2003-10-16

1998-11-09 Application filed by Sanofi Synthelabo SA filed Critical Sanofi Synthelabo SA

2003-10-16 Publication of DE69818091D1 publication Critical patent/DE69818091D1/de

2004-07-01 Application granted granted Critical

2004-07-01 Publication of DE69818091T2 publication Critical patent/DE69818091T2/de

2018-11-10 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DE69818091T 1997-11-17 1998-11-09 Verfahren zur herstellung von derivaten von brommethyl-biphenyl verbindungen Expired - Lifetime DE69818091T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR9714376A FR2771090B1 (fr)	1997-11-17	1997-11-17	Procede de preparation de derives de bromomethyl-biphenyle
FR9714376		1997-11-17
PCT/FR1998/002383 WO1999025681A1 (fr)	1997-11-17	1998-11-09	Procede de preparation de derives de bromomethyl-biphenyle

Publications (2)

Publication Number	Publication Date
DE69818091D1 true DE69818091D1 (de)	2003-10-16
DE69818091T2 DE69818091T2 (de)	2004-07-01

Family

ID=9513439

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69818091T Expired - Lifetime DE69818091T2 (de)	1997-11-17	1998-11-09	Verfahren zur herstellung von derivaten von brommethyl-biphenyl verbindungen

Country Status (15)

Country	Link
US (1)	US6214999B1 (de)
EP (1)	EP1032557B1 (de)
JP (1)	JP4546642B2 (de)
AT (1)	ATE249424T1 (de)
AU (1)	AU1160899A (de)
BR (1)	BR9814651B1 (de)
CA (1)	CA2310324C (de)
DE (1)	DE69818091T2 (de)
DK (1)	DK1032557T5 (de)
ES (1)	ES2207004T3 (de)
FR (1)	FR2771090B1 (de)
HU (1)	HU228640B1 (de)
NO (1)	NO327836B1 (de)
PT (1)	PT1032557E (de)
WO (1)	WO1999025681A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2002354446A1 (en) *	2002-06-12	2003-12-31	Sumitomo Chemical Company, Limited	Process for producing 4'-bromomethyl-2-cyanobiphenyl
US7641181B2 (en) *	2003-01-24	2010-01-05	Liquid Spring Technologies, Inc.	Distributed power suspension system
AU2003234832A1 (en) *	2003-05-20	2004-12-13	Sumitomo Chemical Company, Limited	Process for producing bromomethyl-substituted aromatic carboxylic ester compound
KR100953878B1 (ko) *	2004-09-02	2010-04-22	테바 파마슈티컬 인더스트리즈 리미티드	올메살탄 메독소밀의 정제
CN1976926A (zh) *	2004-09-02	2007-06-06	特瓦制药工业有限公司	奥美沙坦酯的制备
US20070054948A1 (en) *	2004-09-02	2007-03-08	Lilach Hedvati	Purification of olmesartan medoxomil
CA2581723A1 (en) *	2004-10-15	2006-04-27	Teva Pharmaceutical Industries Ltd.	Process for preparing telmisartan
EP1716138A1 (de) *	2004-12-30	2006-11-02	Teva Pharmaceutical Industries Ltd	Verfahren zur herstellung von olmesartan-medoxomil bei einem ph-wert von über 2,5
US20060258727A1 (en) *	2005-01-03	2006-11-16	Lilach Hedvati	Olmesartan medoxomil with reduced levels of impurities
CN101094850A (zh) *	2005-01-03	2007-12-26	特瓦制药工业有限公司	具有较低水平杂质的奥美沙坦酯
WO2008078340A1 (en) *	2006-12-27	2008-07-03	Calyx Chemicals And Pharmaceuticals Ltd.	Process for the separation of 4-bromomethyl-2'-substituted biphenyls from 4,4,-dibromomethyl-2'-substituted biphenyls
HUP0900788A2 (en) *	2009-12-16	2011-11-28	Sanofi Aventis	Process for producing 4-bromomethyl-biphenyl derivatives
CN105399627A (zh) *	2015-10-22	2016-03-16	威特(湖南)药业有限公司	4’-溴甲基联苯-2-羧酸酯的合成方法
AU2017239816B9 (en) *	2016-03-31	2020-09-24	Fujifilm Corporation	Method for producing 5-(bromomethyl)-1-benzothiophene
CN108164434A (zh) *	2017-12-27	2018-06-15	安徽太主科技发展有限公司	一种低成本4′-溴甲基-2-氰基联苯的制备方法
CN113816874B (zh) *	2021-10-30	2024-01-26	大连双硼医药化工有限公司	一种合成4-氰基-2-氟苄醇的工艺方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8806584D0 (en) *	1988-03-19	1988-04-20	Interox Chemicals Ltd	Bromination
JPH06298683A (ja) *	1993-04-15	1994-10-25	Sankyo Co Ltd	光反応による４−（２−置換）フェニルベンジルブロミド類の製造法
JPH0859515A (ja) *	1994-08-12	1996-03-05	Sanko Kagaku Kogyo Kk	モノブロモメチル化芳香族化合物の製造方法
JP2928982B2 (ja) *	1994-10-27	1999-08-03	住化ファインケム株式会社	４’−ブロモメチル−２−シアノビフェニルの製造法
IT1291551B1 (it) *	1997-04-11	1999-01-11	Luso Farmaco Inst	Processo per la preparazione di composti 4-bromometil bifenilici

1997
- 1997-11-17 FR FR9714376A patent/FR2771090B1/fr not_active Expired - Lifetime
1998
- 1998-11-09 CA CA2310324A patent/CA2310324C/en not_active Expired - Lifetime
- 1998-11-09 DE DE69818091T patent/DE69818091T2/de not_active Expired - Lifetime
- 1998-11-09 EP EP98954537A patent/EP1032557B1/de not_active Expired - Lifetime
- 1998-11-09 HU HU0004251A patent/HU228640B1/hu unknown
- 1998-11-09 BR BRPI9814651-3A patent/BR9814651B1/pt not_active IP Right Cessation
- 1998-11-09 ES ES98954537T patent/ES2207004T3/es not_active Expired - Lifetime
- 1998-11-09 US US09/554,566 patent/US6214999B1/en not_active Expired - Lifetime
- 1998-11-09 WO PCT/FR1998/002383 patent/WO1999025681A1/fr active IP Right Grant
- 1998-11-09 AT AT98954537T patent/ATE249424T1/de active
- 1998-11-09 PT PT98954537T patent/PT1032557E/pt unknown
- 1998-11-09 DK DK98954537T patent/DK1032557T5/da active
- 1998-11-09 JP JP2000521065A patent/JP4546642B2/ja not_active Expired - Lifetime
- 1998-11-09 AU AU11608/99A patent/AU1160899A/en not_active Abandoned
2000
- 2000-05-16 NO NO20002530A patent/NO327836B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
JP4546642B2 (ja)	2010-09-15
EP1032557B1 (de)	2003-09-10
WO1999025681A1 (fr)	1999-05-27
ES2207004T3 (es)	2004-05-16
NO20002530L (no)	2000-07-17
AU1160899A (en)	1999-06-07
FR2771090B1 (fr)	2000-02-04
BR9814651A (pt)	2000-10-03
EP1032557A1 (de)	2000-09-06
BR9814651B1 (pt)	2010-12-14
US6214999B1 (en)	2001-04-10
ATE249424T1 (de)	2003-09-15
HUP0004251A3 (en)	2003-05-28
FR2771090A1 (fr)	1999-05-21
DK1032557T3 (da)	2004-01-19
CA2310324A1 (en)	1999-05-27
HU228640B1 (en)	2013-04-29
CA2310324C (en)	2010-01-26
PT1032557E (pt)	2004-02-27
JP2001523658A (ja)	2001-11-27
NO20002530D0 (no)	2000-05-16
NO327836B1 (no)	2009-10-05
DE69818091T2 (de)	2004-07-01
HUP0004251A2 (hu)	2001-04-28
DK1032557T5 (da)	2004-03-08

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Legal Events

Date

Code

Title

Description

2004-10-07

8364

No opposition during term of opposition

2005-04-21

8327

Change in the person/name/address of the patent owner

Owner name: SANOFI-AVENTIS, PARIS, FR

2013-02-05

R082

Change of representative

Ref document number: 1032557

Country of ref document: EP

Representative=s name: TER MEER STEINMEISTER & PARTNER GBR PATENTANWA, DE