DE69810724T2 - Verwendung von Protein C Inhibitor zur Behandlung disseminierter intravasaler Gerinnung (DIC) - Google Patents

Verwendung von Protein C Inhibitor zur Behandlung disseminierter intravasaler Gerinnung (DIC)

Info

Publication number
DE69810724T2
DE69810724T2 DE69810724T DE69810724T DE69810724T2 DE 69810724 T2 DE69810724 T2 DE 69810724T2 DE 69810724 T DE69810724 T DE 69810724T DE 69810724 T DE69810724 T DE 69810724T DE 69810724 T2 DE69810724 T2 DE 69810724T2
Authority
DE
Germany
Prior art keywords
inhibitor
protein
dic
treatment
intravascular coagulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69810724T
Other languages
English (en)
Other versions
DE69810724D1 (de
Inventor
Mitsugu Fujita
Yoshikazu Komurasaki
Keihide Koh
Hiromichi Ishikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
JCR Pharmaceuticals Co Ltd
Original Assignee
JCR Pharmaceuticals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JCR Pharmaceuticals Co Ltd filed Critical JCR Pharmaceuticals Co Ltd
Publication of DE69810724D1 publication Critical patent/DE69810724D1/de
Application granted granted Critical
Publication of DE69810724T2 publication Critical patent/DE69810724T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/57—Protease inhibitors from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
DE69810724T 1997-08-11 1998-08-11 Verwendung von Protein C Inhibitor zur Behandlung disseminierter intravasaler Gerinnung (DIC) Expired - Fee Related DE69810724T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP9230294A JPH1160500A (ja) 1997-08-11 1997-08-11 血液凝固異常亢進抑制剤

Publications (2)

Publication Number Publication Date
DE69810724D1 DE69810724D1 (de) 2003-02-20
DE69810724T2 true DE69810724T2 (de) 2003-05-08

Family

ID=16905575

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69810724T Expired - Fee Related DE69810724T2 (de) 1997-08-11 1998-08-11 Verwendung von Protein C Inhibitor zur Behandlung disseminierter intravasaler Gerinnung (DIC)

Country Status (6)

Country Link
US (1) US5948752A (de)
EP (1) EP0904785B1 (de)
JP (1) JPH1160500A (de)
AT (1) ATE231001T1 (de)
CA (1) CA2244801A1 (de)
DE (1) DE69810724T2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002010783A (ja) * 2000-06-29 2002-01-15 Jcr Pharmaceuticals Co Ltd 改変型ヒトプロテインｃインヒビター
TW200407335A (en) * 2002-07-22 2004-05-16 Chugai Pharmaceutical Co Ltd Non-neutralizing antibody to inhibit the inactivation of activated protein C
JPWO2004065418A1 (ja) * 2003-01-20 2006-06-29 中外製薬株式会社 抗ｐｃｉ中和抗体
FR2945126B1 (fr) * 2009-04-29 2019-11-01 Commissariat A L'energie Atomique Procede et appareil de comptage des thrombocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3705745A1 (de) * 1987-02-23 1988-09-01 Behringwerke Ag Protein c-inhibitor (pci) als pharmazeutikum und in vitro-diagnostikum, verfahren zur herstellung eines solchen pharmazeutikums oder diagnostikums sowie ein mittel enthaltend pci
AU2299592A (en) * 1991-07-02 1993-02-11 Children's Medical Center Corporation Treatment of periodontal disease with protease inhibitors

Also Published As

Publication number Publication date
ATE231001T1 (de) 2003-02-15
DE69810724D1 (de) 2003-02-20
EP0904785B1 (de) 2003-01-15
US5948752A (en) 1999-09-07
CA2244801A1 (en) 1999-02-11
JPH1160500A (ja) 1999-03-02
EP0904785A1 (de) 1999-03-31

Similar Documents

Publication Publication Date Title
ATE114113T1 (de) Verwendung von droloxifen bei der behandlung von knochenerkrankungen.
DK0797666T3 (da) Genetisk manipulerede humane Kunitz-domæner, der inhiberer human neutrofil elastase
BR9507758A (pt) Fração de copolímero-1 e composição para o tratamento de esclerose múltipla
PT842934E (pt) Agonistas de 5-ht1f
NO912630D0 (no) Fremgangsmaate for fremstilling av nye 2,6-dialkyl-4-silyl-fenoler.
DE69130614D1 (de) Herbizide, substituierte aryl-haloalkylpyrazole
MXPA02001911A (es) Anticuerpos ctla-4 humanos y sus usos.
DE69521620D1 (de) Verwendung von 9-deoxyprostaglandinderivaten zur behandlung von glaukom
DE60121808D1 (de) Verwendung eines polypeptids, welches die extrazelluläre domäne von il-20ra und il-20rb enthält, zur behandlung von entzündungen
ATE271390T1 (de) Verwendung von azithromycin zur topischen behandlung von augeninfektionen
ATE335499T1 (de) Zusammensetzungen zur behandlung von staphylococcus aureus infektionen
DE69405919D1 (de) Zusammensetzungen zur Behandlung von Keratinfasern
DE69810724T2 (de) Verwendung von Protein C Inhibitor zur Behandlung disseminierter intravasaler Gerinnung (DIC)
FI904852A0 (fi) Antikoagulantpeptider.
BR9612074A (pt) Novos 4-(1h-benzimidazol-2-il)(1,4) diazepanos substituidos úteis para o tratamento de doenças alérgicas
ES2073391T3 (es) Metodo y composiciones terapeuticas para el tratamiento de trastornos de perdidas de sangre.
SE9003374D0 (sv) A collagen binding protein as well as its preparation
ITMI920955A1 (it) Idrogeli di tipo polietereammidoamminico come materiali eparinizzabili
ATE113591T1 (de) 4-benzyl-5-phenyl-2,4-dihydro-3h-1,2,4-triazol- - one und ihre verwendung als antikonvulsiva.
ATE273711T1 (de) Verwendung von niedermolekularem heparin zur behandlung und/oder prophylaxe motoneuronaler krankheiten
DE69905489T2 (de) Protein c zur behandlung von sichelzellanämie und thalassämie
DE69930419D1 (de) Verwendung von menschliche protein c zur herstellung eines arzneimittels zur behandlung von heparininduzierter thrombozytopenie
ATE282609T1 (de) Neue substituierte n-methyl-n-(4-(4-(1h- benzimidazol-2-yl) (1,4)diazepan-1-yl)-2- (aryl)butyl)benzamide zur behandlung von allergischen krankheiten
ATE359088T1 (de) Verwendung von interleukin-18 zur behandlung von uv-assoziierten hautkrankheiten
ATE292970T1 (de) Topische zusammensetzung enthaltend brucin und ihre verwendung zur behandlung von hautschäden

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee