DE69806003D1 - Dna polymerasen, die verbesserte fähigkeiten zum einbau markierter nukleotide besitzen - Google Patents

Dna polymerasen, die verbesserte fähigkeiten zum einbau markierter nukleotide besitzen

Info

Publication number
DE69806003D1
DE69806003D1 DE69806003T DE69806003T DE69806003D1 DE 69806003 D1 DE69806003 D1 DE 69806003D1 DE 69806003 T DE69806003 T DE 69806003T DE 69806003 T DE69806003 T DE 69806003T DE 69806003 D1 DE69806003 D1 DE 69806003D1
Authority
DE
Germany
Prior art keywords
install
dna polymerases
improved ability
marked nucleotides
nucleotides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69806003T
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English (en)
Other versions
DE69806003T2 (de
Inventor
John Brandis
Curtis Bloom
Jack Richards
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Applied Biosystems LLC
Original Assignee
PE Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21906408&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69806003(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by PE Corp filed Critical PE Corp
Publication of DE69806003D1 publication Critical patent/DE69806003D1/de
Application granted granted Critical
Publication of DE69806003T2 publication Critical patent/DE69806003T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C12N9/1252—DNA-directed DNA polymerase (2.7.7.7), i.e. DNA replicase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Saccharide Compounds (AREA)
DE69806003T 1997-03-12 1998-03-12 Dna polymerasen, die verbesserte fähigkeiten zum einbau markierter nukleotide besitzen Expired - Lifetime DE69806003T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3961097P 1997-03-12 1997-03-12
PCT/US1998/005095 WO1998040496A1 (en) 1997-03-12 1998-03-12 Dna polymerases having improved labeled nucleotide incorporation properties

Publications (2)

Publication Number Publication Date
DE69806003D1 true DE69806003D1 (de) 2002-07-18
DE69806003T2 DE69806003T2 (de) 2003-01-30

Family

ID=21906408

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69806003T Expired - Lifetime DE69806003T2 (de) 1997-03-12 1998-03-12 Dna polymerasen, die verbesserte fähigkeiten zum einbau markierter nukleotide besitzen
DE69841023T Expired - Lifetime DE69841023D1 (de) 1997-03-12 1998-03-12 DNA Polymerasen mit verbesserten Fähigkeiten zum Einbau von markierten Nukleotiden

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69841023T Expired - Lifetime DE69841023D1 (de) 1997-03-12 1998-03-12 DNA Polymerasen mit verbesserten Fähigkeiten zum Einbau von markierten Nukleotiden

Country Status (7)

Country Link
US (7) US6265193B1 (de)
EP (3) EP0983364B1 (de)
JP (2) JP3435416B2 (de)
AU (1) AU743025B2 (de)
CA (1) CA2283789C (de)
DE (2) DE69806003T2 (de)
WO (1) WO1998040496A1 (de)

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US20100311959A1 (en) 2010-12-09
US6265193B1 (en) 2001-07-24
US20060088879A1 (en) 2006-04-27
AU743025B2 (en) 2002-01-17
EP0983364A1 (de) 2000-03-08
US20110244548A1 (en) 2011-10-06
AU6466998A (en) 1998-09-29
EP0983364B1 (de) 2002-06-12
US20130273526A1 (en) 2013-10-17
EP2208789B1 (de) 2015-07-22
EP2202312A3 (de) 2010-07-07
EP2208789A1 (de) 2010-07-21
EP2202312A2 (de) 2010-06-30
CA2283789C (en) 2005-07-05
CA2283789A1 (en) 1998-09-17
US7897738B2 (en) 2011-03-01
JP3435416B2 (ja) 2003-08-11
DE69806003T2 (de) 2003-01-30
JP2003144143A (ja) 2003-05-20
US20020164591A1 (en) 2002-11-07
EP2202312B1 (de) 2016-01-06

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