WO2001047944A3 - Nucleic acids containing single nucleotide polymorphisms and methods of use thereof - Google Patents

Nucleic acids containing single nucleotide polymorphisms and methods of use thereof Download PDF

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Publication number
WO2001047944A3
WO2001047944A3 PCT/US2000/035498 US0035498W WO0147944A3 WO 2001047944 A3 WO2001047944 A3 WO 2001047944A3 US 0035498 W US0035498 W US 0035498W WO 0147944 A3 WO0147944 A3 WO 0147944A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
methods
nucleotide polymorphisms
acids containing
containing single
Prior art date
Application number
PCT/US2000/035498
Other languages
French (fr)
Other versions
WO2001047944A2 (en
Inventor
Richard A Shimkets
Martin Leach
Original Assignee
Curagen Corp
Richard A Shimkets
Martin Leach
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Curagen Corp, Richard A Shimkets, Martin Leach filed Critical Curagen Corp
Priority to AU29145/01A priority Critical patent/AU2914501A/en
Priority to CA002395926A priority patent/CA2395926A1/en
Priority to EP00993615A priority patent/EP1244688A1/en
Publication of WO2001047944A2 publication Critical patent/WO2001047944A2/en
Publication of WO2001047944A3 publication Critical patent/WO2001047944A3/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

Abstract

The invention provides nucleic acids containing single-nucleotide polymorphisms identified for transcribed human sequences, as well as methods of using the nucleic acids.
PCT/US2000/035498 1999-12-28 2000-12-28 Nucleic acids containing single nucleotide polymorphisms and methods of use thereof WO2001047944A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU29145/01A AU2914501A (en) 1999-12-28 2000-12-28 Nucleic acids containing single nucleotide polymorphisms and methods of use thereof
CA002395926A CA2395926A1 (en) 1999-12-28 2000-12-28 Nucleic acids containing single nucleotide polymorphisms and methods of use thereof
EP00993615A EP1244688A1 (en) 1999-12-28 2000-12-28 Nucleic acids containing single nucleotide polymorphisms and methods of use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17341999P 1999-12-28 1999-12-28
US60/173,419 1999-12-28

Publications (2)

Publication Number Publication Date
WO2001047944A2 WO2001047944A2 (en) 2001-07-05
WO2001047944A3 true WO2001047944A3 (en) 2003-02-20

Family

ID=22631931

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/035498 WO2001047944A2 (en) 1999-12-28 2000-12-28 Nucleic acids containing single nucleotide polymorphisms and methods of use thereof

Country Status (3)

Country Link
AU (1) AU2914501A (en)
CA (1) CA2395926A1 (en)
WO (1) WO2001047944A2 (en)

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US7258860B2 (en) 1998-03-18 2007-08-21 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US6960570B2 (en) 1998-03-18 2005-11-01 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US6696247B2 (en) 1998-03-18 2004-02-24 Corixa Corporation Compounds and methods for therapy and diagnosis of lung cancer
US7579160B2 (en) 1998-03-18 2009-08-25 Corixa Corporation Methods for the detection of cervical cancer
US20030083284A1 (en) * 2001-08-01 2003-05-01 Isis Pharmaceuticals Inc. Antisense modulation of p70 S6 kinase expression
US20030232056A1 (en) 1999-09-10 2003-12-18 Corixa Corporation Compositions and methods for the therapy and diagnosis of ovarian cancer
US6710170B2 (en) 1999-09-10 2004-03-23 Corixa Corporation Compositions and methods for the therapy and diagnosis of ovarian cancer
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US7235358B2 (en) 2001-06-08 2007-06-26 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
EP1308522A1 (en) * 2001-11-05 2003-05-07 Haferlach, Torsten, PD Dr. Dr. Novel genetic markers for leukemias
FR2836484B1 (en) * 2002-02-25 2005-02-04 Assist Publ Hopitaux De Paris METHOD OF IN VITRO DETECTION OF CANCERS BY THE EVIDENCE OF ALLELIC IMBALANCES OF INSERT-DELETION MARKERS
WO2003085378A2 (en) * 2002-04-03 2003-10-16 Syngenta Participations Ag Detection of wheat and barley fungal pathogens which are resistant to certain fungicides using the polymerase chain reaction
US7301017B2 (en) * 2002-05-30 2007-11-27 Kolesnick Richard N Kinase suppressor of Ras inactivation for therapy of Ras mediated tumorigenesis
CN1244375C (en) * 2003-01-03 2006-03-08 中国科学院上海生命科学研究院 Human liver regeneration related protein and its application
EP1911853A3 (en) * 2003-06-10 2011-11-16 bioMerieux B.V. Nucleic acid sequences that can be used as primers and probes in the amplification and detection of SARS coronavirus
US7871610B2 (en) 2003-08-12 2011-01-18 Dyax Corp. Antibodies to Tie1 ectodomain
US7485297B2 (en) 2003-08-12 2009-02-03 Dyax Corp. Method of inhibition of vascular development using an antibody
US7294704B2 (en) 2003-08-15 2007-11-13 Diadexus, Inc. Pro108 antibody compositions and methods of use and use of Pro108 to assess cancer risk
CN101313063B (en) * 2005-08-09 2013-04-03 肿瘤疗法·科学股份有限公司 Cancer-rejection antigen peptide derived from glypican-3 (GPC3) for use in HLA-A2-positive patient and pharmaceutical comprising the antigen
EP2041338A4 (en) * 2006-06-09 2009-09-30 Univ British Columbia Interferon gamma polymorphisms as indicators of subject outcome in critically ill subjects
GB2453589A (en) 2007-10-12 2009-04-15 King S College London Protease inhibition
FR2937322B1 (en) * 2008-10-22 2013-02-22 Vect Horus PEPTIDE DERIVATIVES AND THEIR USE AS VECTORS OF MOLECULES IN THE FORM OF CONJUGATES
US9890202B2 (en) 2010-07-19 2018-02-13 Yeda Research And Development Co. Ltd. Peptides based on the transmembrane domain of a toll-like receptor (TLR) for treatment of TLR-mediated diseases
GB201511546D0 (en) 2015-07-01 2015-08-12 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
EP3919507A3 (en) 2015-07-01 2022-01-12 Immatics Biotechnologies GmbH Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
WO2018115879A1 (en) 2016-12-21 2018-06-28 Mereo Biopharma 3 Limited Use of anti-sclerostin antibodies in the treatment of osteogenesis imperfecta
CA3061905A1 (en) * 2017-05-24 2018-11-29 The Regents Of The University Of California Antisense therapies for treating cancer
GB201714330D0 (en) * 2017-09-06 2017-10-18 Järver Peter Oligonucleotides

Citations (5)

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WO1992013069A1 (en) * 1991-01-21 1992-08-06 Imperial College Of Science, Technology & Medicine Test and model for alzheimer's disease
US5656477A (en) * 1992-05-01 1997-08-12 American Cyanamid Company Amyloid precursor proteins and method of using same to assess agents which down-regulate formation of β-amyloid peptide
WO1998020165A2 (en) * 1996-11-06 1998-05-14 Whitehead Institute For Biomedical Research Biallelic markers
US5795963A (en) * 1992-06-04 1998-08-18 Alzheimer's Institute Of America Amyloid precursor protein in alzheimer's disease
WO1998038846A2 (en) * 1997-03-07 1998-09-11 Affymetrix, Inc. Genetic compositions and methods

Patent Citations (5)

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Publication number Priority date Publication date Assignee Title
WO1992013069A1 (en) * 1991-01-21 1992-08-06 Imperial College Of Science, Technology & Medicine Test and model for alzheimer's disease
US5656477A (en) * 1992-05-01 1997-08-12 American Cyanamid Company Amyloid precursor proteins and method of using same to assess agents which down-regulate formation of β-amyloid peptide
US5795963A (en) * 1992-06-04 1998-08-18 Alzheimer's Institute Of America Amyloid precursor protein in alzheimer's disease
WO1998020165A2 (en) * 1996-11-06 1998-05-14 Whitehead Institute For Biomedical Research Biallelic markers
WO1998038846A2 (en) * 1997-03-07 1998-09-11 Affymetrix, Inc. Genetic compositions and methods

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FAN J ET AL: "Genetic mapping: Finding and analyzing single-nucleotide polymorphisms with high-density DNA arrays", AMERICAN JOURNAL OF HUMAN GENETICS, UNIVERSITY OF CHICAGO PRESS, CHICAGO,, US, vol. 61, no. 4, SUPPL, 1 October 1997 (1997-10-01), pages 1601, XP002089397, ISSN: 0002-9297 *
WANG D G ET AL: "Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 280, 1998, pages 1077 - 1082, XP002089398, ISSN: 0036-8075 *

Also Published As

Publication number Publication date
WO2001047944A2 (en) 2001-07-05
AU2914501A (en) 2001-07-09
CA2395926A1 (en) 2001-07-05

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