DE69801682T2 - Versteifte trimethin-cyaninfarbstoffe - Google Patents
Versteifte trimethin-cyaninfarbstoffeInfo
- Publication number
- DE69801682T2 DE69801682T2 DE69801682T DE69801682T DE69801682T2 DE 69801682 T2 DE69801682 T2 DE 69801682T2 DE 69801682 T DE69801682 T DE 69801682T DE 69801682 T DE69801682 T DE 69801682T DE 69801682 T2 DE69801682 T2 DE 69801682T2
- Authority
- DE
- Germany
- Prior art keywords
- atoms
- groups
- optionally
- cyanine dyes
- radical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed systems contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/0075—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain being part of an heterocyclic ring
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B23/00—Methine or polymethine dyes, e.g. cyanine dyes
- C09B23/02—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups
- C09B23/06—Methine or polymethine dyes, e.g. cyanine dyes the polymethine chain containing an odd number of >CH- or >C[alkyl]- groups three >CH- groups, e.g. carbocyanines
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Indole Compounds (AREA)
- Macromonomer-Based Addition Polymer (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Vehicle Interior And Exterior Ornaments, Soundproofing, And Insulation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US99221297A | 1997-12-17 | 1997-12-17 | |
PCT/US1998/026665 WO1999031181A1 (en) | 1997-12-17 | 1998-12-16 | Rigidized trimethine cyanine dyes |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69801682D1 DE69801682D1 (en) | 2001-10-18 |
DE69801682T2 true DE69801682T2 (de) | 2002-06-20 |
Family
ID=25538049
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69801682T Expired - Lifetime DE69801682T2 (de) | 1997-12-17 | 1998-12-16 | Versteifte trimethin-cyaninfarbstoffe |
Country Status (10)
Country | Link |
---|---|
US (1) | US6686145B1 (de) |
EP (1) | EP1042407B1 (de) |
JP (1) | JP4927253B2 (de) |
AT (1) | ATE205515T1 (de) |
AU (1) | AU760598B2 (de) |
CA (1) | CA2314188C (de) |
DE (1) | DE69801682T2 (de) |
DK (1) | DK1042407T3 (de) |
ES (1) | ES2165711T3 (de) |
WO (1) | WO1999031181A1 (de) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6133445A (en) | 1997-12-17 | 2000-10-17 | Carnegie Mellon University | Rigidized trimethine cyanine dyes |
AU6206800A (en) * | 1999-07-06 | 2001-01-22 | Surromed, Inc. | Bridged fluorescent dyes, their preparation and their use in assays |
DE19937024A1 (de) * | 1999-08-05 | 2001-02-08 | Bayer Ag | Verwendung von Acylsulfonamido substituierten Polymethin-Farbstoffen als Fluoreszenz-Farbstoffe und/oder Marker |
EP1223197B1 (de) | 2001-01-03 | 2012-08-08 | Visen Medical, Inc. | Symmetrische, monofunktionalisierte Polymethinfarbstoffe als Markierungsreagenzien |
EP1221465A1 (de) | 2001-01-03 | 2002-07-10 | Innosense S.r.l. | Symmetrische, monofunktionalisierte Polymethinfarbstoffe als Markierungsreagenzien |
ATE517152T1 (de) * | 2002-05-10 | 2011-08-15 | Univ Carnegie Mellon | Chirale indole als zwischenprodukte und daraus hergestellte cyaninfluoreszenzfarbstoffe mit funktionellen gruppen |
ES2461858T3 (es) | 2004-08-13 | 2014-05-21 | Epoch Biosciences, Inc. | Colorantes fluorescentes de fosfonato y conjugados |
FR2875131B1 (fr) * | 2004-09-13 | 2007-09-28 | Oreal | Composition comprenant au moins un derive substitue de carbocyanine, procede de traitement des fibres keratiniques la mettant en oeuvre, dispositif et utilisation |
US7419511B2 (en) | 2004-09-13 | 2008-09-02 | L'oreal, S.A. | Compositions comprising at least one substituted carbocyanin derivative, processes for treating keratin fibers using them, device therefor and uses thereof |
US7425221B2 (en) | 2004-09-13 | 2008-09-16 | L'oreal S.A. | Composition comprising at least one substituted derivative of carbocyanine, method for treating keratin fibers using it, device and use |
US7427301B2 (en) | 2004-09-13 | 2008-09-23 | L'ORéAL S.A. | Composition comprising at least one substituted carbocyanin derivative, process for treating keratin fibers using it, device therefor and use thereof |
EP1794237A2 (de) | 2004-09-30 | 2007-06-13 | GE Healthcare UK Limited | Fluoreszierende nukleotidanaloga |
US7282373B2 (en) | 2004-12-23 | 2007-10-16 | Rutgers, The State University Of New Jersey | Ultra-high specificity fluorescent labeling |
US7381572B2 (en) | 2004-12-23 | 2008-06-03 | Rutgers, The State University Of New Jersey | Reagents and procedures for multi-label high-specificity labeling |
WO2006083846A2 (en) * | 2005-02-01 | 2006-08-10 | Sigma-Aldrich Co. | Detection of polyamino acids using trimethincyanine dyes |
US7737281B2 (en) * | 2005-05-24 | 2010-06-15 | Enzo Life Sciences, Inc. C/O Enzo Biochem, Inc. | Purine based fluorescent dyes |
US8357801B2 (en) | 2005-05-24 | 2013-01-22 | Enzo Life Sciences, Inc. | Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits |
US7569695B2 (en) * | 2005-05-24 | 2009-08-04 | Enzo Life Sciences, Inc. | Dyes for the detection or quantification of desirable target molecules |
ES2612738T3 (es) | 2005-09-02 | 2017-05-18 | Visen Medical, Inc. | Agentes de formación de imágenes fluorescentes biocompatibles |
ES2618361T3 (es) | 2005-09-02 | 2017-06-21 | Visen Medical, Inc. | Marcadores colorantes fluorescentes que contienen sulfonamida N,N-disustituida biocompatible |
JP5416970B2 (ja) | 2005-09-02 | 2014-02-12 | ビセン メディカル, インコーポレイテッド | ニコチン酸及びピコリン酸誘導近赤外線蛍光団 |
EP1954763B1 (de) * | 2005-11-28 | 2016-11-16 | Dako Denmark A/S | Cyaninfarbstoffe und verfahren zur aufspürung eines angriffsziels und verwendung der genannten farbstoffe |
US9250249B2 (en) | 2008-09-08 | 2016-02-02 | Enzo Biochem, Inc. | Autophagy and phospholipidosis pathway assays |
US9334281B2 (en) * | 2008-09-08 | 2016-05-10 | Enzo Life Sciences, Inc. | Fluorochromes for organelle tracing and multi-color imaging |
EP2376481B1 (de) | 2009-01-13 | 2013-08-07 | Glaxo Group Limited | Pyrimidinecarboxamidderivate als syk-kinasehemmer |
GB201007203D0 (en) | 2010-04-29 | 2010-06-16 | Glaxo Group Ltd | Novel compounds |
WO2013148498A1 (en) | 2012-03-27 | 2013-10-03 | Ventana Medical Systems, Inc. | Signaling conjugates and methods of use |
US10473666B2 (en) * | 2015-07-16 | 2019-11-12 | Sfc Co., Ltd. | Dye compounds |
WO2019040825A1 (en) | 2017-08-24 | 2019-02-28 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | CONFORMATIONAL RESTRICTION OF CYANINE FLUOROPHORES IN A FAR RED RANGE AND CLOSE INFRARED |
KR102593166B1 (ko) * | 2017-11-23 | 2023-10-25 | 에스에프씨 주식회사 | 표지용 염료 및 이를 포함하는 표지용 키트 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3753721A (en) | 1970-08-13 | 1973-08-21 | Eastman Kodak Co | Photographic materials |
US3915715A (en) | 1970-08-13 | 1975-10-28 | Eastman Kodak Co | Silver halide photographic materials containing a high weight ratio of gold to sulfur sensitizers and a sensitizing methine dye |
US3854956A (en) | 1970-10-30 | 1974-12-17 | Eastman Kodak Co | Dyestuffs and spectral sensitizers for silver halide |
US3821233A (en) | 1970-10-30 | 1974-06-28 | Eastman Kodak Co | Rigidized carbocyanine dyes containing a pyrida-dipyridinium nucleus |
US3679427A (en) | 1970-10-30 | 1972-07-25 | Eastman Kodak Co | Rigidized carbocyanine dyes and photographic emulsions |
US3864644A (en) * | 1971-03-22 | 1975-02-04 | Eastman Kodak Co | Dye lasers including rigidized carbocyanine dyes |
CA985493A (en) | 1971-03-22 | 1976-03-16 | Eastman Kodak Company | Dye lasers including rigidized carbocyanine dyes |
US3904637A (en) | 1972-04-19 | 1975-09-09 | Eastman Kodak Co | 7'a'h,8'a'h-bisbenzothiazolo(3,2-a;-3',2'-a)pyrano (3,2-c;5,6-c'+9 dipyridinium compounds and related derivatives thereof |
EP0747448B1 (de) * | 1995-06-07 | 2002-11-06 | Carnegie-Mellon University | Versteifte Monomethin-Cyaninfarbstoffe |
US5658735A (en) | 1995-11-09 | 1997-08-19 | Biometric Imaging, Inc. | Cyclized fluorescent nucleic acid intercalating cyanine dyes and nucleic acid detection methods |
US6133445A (en) | 1997-12-17 | 2000-10-17 | Carnegie Mellon University | Rigidized trimethine cyanine dyes |
-
1998
- 1998-12-16 CA CA002314188A patent/CA2314188C/en not_active Expired - Lifetime
- 1998-12-16 AU AU18288/99A patent/AU760598B2/en not_active Expired
- 1998-12-16 JP JP2000539092A patent/JP4927253B2/ja not_active Expired - Lifetime
- 1998-12-16 DK DK98963218T patent/DK1042407T3/da active
- 1998-12-16 DE DE69801682T patent/DE69801682T2/de not_active Expired - Lifetime
- 1998-12-16 ES ES98963218T patent/ES2165711T3/es not_active Expired - Lifetime
- 1998-12-16 EP EP98963218A patent/EP1042407B1/de not_active Expired - Lifetime
- 1998-12-16 US US09/581,679 patent/US6686145B1/en not_active Expired - Lifetime
- 1998-12-16 AT AT98963218T patent/ATE205515T1/de active
- 1998-12-16 WO PCT/US1998/026665 patent/WO1999031181A1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
WO1999031181A1 (en) | 1999-06-24 |
ES2165711T3 (es) | 2002-03-16 |
US6686145B1 (en) | 2004-02-03 |
JP4927253B2 (ja) | 2012-05-09 |
EP1042407B1 (de) | 2001-09-12 |
EP1042407A1 (de) | 2000-10-11 |
DE69801682D1 (en) | 2001-10-18 |
CA2314188A1 (en) | 1999-06-24 |
AU1828899A (en) | 1999-07-05 |
AU760598B2 (en) | 2003-05-15 |
JP2002508428A (ja) | 2002-03-19 |
DK1042407T3 (da) | 2001-12-27 |
CA2314188C (en) | 2009-11-17 |
ATE205515T1 (de) | 2001-09-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |