DE69800169T2 - Stabile Wasser-in-Öl-in-Wasser Emulsion und ihre Verwendung als kosmetische und/oder dermatologische Zusammensetzung - Google Patents

Stabile Wasser-in-Öl-in-Wasser Emulsion und ihre Verwendung als kosmetische und/oder dermatologische Zusammensetzung

Info

Publication number: DE69800169T2
Authority: DE; Germany
Prior art keywords: acid; emulsion; oil; water; emulsion according
Prior art date: 1997-10-03
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69800169T

Other languages

German (de)

English (en)

Other versions

DE69800169D1 (de

Inventor

Isabelle Afriat

Florence Chanvin

Carole Guiramand

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

LOreal SA

Original Assignee

LOreal SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1997-10-03

Filing date

1998-09-11

Publication date

2000-09-28

1998-09-11 Application filed by LOreal SA filed Critical LOreal SA

2000-07-06 Publication of DE69800169D1 publication Critical patent/DE69800169D1/de

2000-09-28 Application granted granted Critical

2000-09-28 Publication of DE69800169T2 publication Critical patent/DE69800169T2/de

2018-09-12 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

239000000203 mixture Substances 0.000 title claims abstract description 49
239000002537 cosmetic Substances 0.000 title claims description 14
239000007764 o/w emulsion Substances 0.000 title description 3
239000000839 emulsion Substances 0.000 claims abstract description 97
-1 poly(acrylamidomethylpropanesulphonic acid) Polymers 0.000 claims abstract description 61
239000012071 phase Substances 0.000 claims abstract description 47
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 40
239000000178 monomer Substances 0.000 claims abstract description 38
239000008346 aqueous phase Substances 0.000 claims abstract description 15
235000013870 dimethyl polysiloxane Nutrition 0.000 claims abstract description 15
229920000435 poly(dimethylsiloxane) Polymers 0.000 claims abstract description 15
150000001768 cations Chemical class 0.000 claims abstract description 12
238000000034 method Methods 0.000 claims abstract description 11
239000004205 dimethyl polysiloxane Substances 0.000 claims abstract description 10
150000001732 carboxylic acid derivatives Chemical class 0.000 claims abstract description 9
229920001577 copolymer Polymers 0.000 claims abstract description 9
238000004132 cross linking Methods 0.000 claims abstract description 9
239000003995 emulsifying agent Substances 0.000 claims abstract description 9
229940008099 dimethicone Drugs 0.000 claims abstract description 8
150000008064 anhydrides Chemical class 0.000 claims abstract description 6
230000000699 topical effect Effects 0.000 claims abstract description 5
NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims abstract description 4
239000004480 active ingredient Substances 0.000 claims description 38
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 21
239000003921 oil Substances 0.000 claims description 20
229920000642 polymer Polymers 0.000 claims description 20
229920002545 silicone oil Polymers 0.000 claims description 15
239000007864 aqueous solution Substances 0.000 claims description 12
210000004400 mucous membrane Anatomy 0.000 claims description 12
FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 11
235000010323 ascorbic acid Nutrition 0.000 claims description 11
229960005070 ascorbic acid Drugs 0.000 claims description 11
239000011668 ascorbic acid Substances 0.000 claims description 11
229920001296 polysiloxane Polymers 0.000 claims description 11
102000011782 Keratins Human genes 0.000 claims description 10
108010076876 Keratins Proteins 0.000 claims description 10
125000000217 alkyl group Chemical group 0.000 claims description 10
239000003755 preservative agent Substances 0.000 claims description 10
230000001804 emulsifying effect Effects 0.000 claims description 9
238000002360 preparation method Methods 0.000 claims description 9
239000001257 hydrogen Substances 0.000 claims description 8
229910052739 hydrogen Inorganic materials 0.000 claims description 8
239000002904 solvent Substances 0.000 claims description 8
FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 7
230000002378 acidificating effect Effects 0.000 claims description 7
239000000835 fiber Substances 0.000 claims description 7
229920005862 polyol Polymers 0.000 claims description 7
150000003077 polyols Chemical class 0.000 claims description 7
AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims description 6
QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 claims description 6
KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 6
238000004140 cleaning Methods 0.000 claims description 6
150000002148 esters Chemical class 0.000 claims description 6
125000004435 hydrogen atom Chemical group [H]* 0.000 claims description 6
239000001301 oxygen Substances 0.000 claims description 6
229910052760 oxygen Inorganic materials 0.000 claims description 6
229960003471 retinol Drugs 0.000 claims description 6
235000020944 retinol Nutrition 0.000 claims description 6
239000011607 retinol Substances 0.000 claims description 6
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 5
MNRBGFKCVTVNBA-UHFFFAOYSA-N 2-Hydroxyundecanoate Chemical compound CCCCCCCCCC(O)C(O)=O MNRBGFKCVTVNBA-UHFFFAOYSA-N 0.000 claims description 4
CPLYLXYEVLGWFJ-UHFFFAOYSA-N 2-hydroxyarachidic acid Chemical compound CCCCCCCCCCCCCCCCCCC(O)C(O)=O CPLYLXYEVLGWFJ-UHFFFAOYSA-N 0.000 claims description 4
GHPVDCPCKSNJDR-UHFFFAOYSA-N 2-hydroxydecanoic acid Chemical compound CCCCCCCCC(O)C(O)=O GHPVDCPCKSNJDR-UHFFFAOYSA-N 0.000 claims description 4
JGHSBPIZNUXPLA-UHFFFAOYSA-N 2-hydroxyhexadecanoic acid Chemical compound CCCCCCCCCCCCCCC(O)C(O)=O JGHSBPIZNUXPLA-UHFFFAOYSA-N 0.000 claims description 4
JYZJYKOZGGEXSX-UHFFFAOYSA-N 2-hydroxymyristic acid Chemical compound CCCCCCCCCCCCC(O)C(O)=O JYZJYKOZGGEXSX-UHFFFAOYSA-N 0.000 claims description 4
KIHBGTRZFAVZRV-UHFFFAOYSA-N 2-hydroxyoctadecanoic acid Chemical compound CCCCCCCCCCCCCCCCC(O)C(O)=O KIHBGTRZFAVZRV-UHFFFAOYSA-N 0.000 claims description 4
RGHNJXZEOKUKBD-SQOUGZDYSA-N D-gluconic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 claims description 4
VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims description 4
IAJILQKETJEXLJ-UHFFFAOYSA-N Galacturonsaeure Natural products O=CC(O)C(O)C(O)C(O)C(O)=O IAJILQKETJEXLJ-UHFFFAOYSA-N 0.000 claims description 4
LCTONWCANYUPML-UHFFFAOYSA-N Pyruvic acid Chemical compound CC(=O)C(O)=O LCTONWCANYUPML-UHFFFAOYSA-N 0.000 claims description 4
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 claims description 4
239000000654 additive Substances 0.000 claims description 4
150000001875 compounds Chemical class 0.000 claims description 4
239000000284 extract Substances 0.000 claims description 4
ROBFUDYVXSDBQM-UHFFFAOYSA-N hydroxymalonic acid Chemical compound OC(=O)C(O)C(O)=O ROBFUDYVXSDBQM-UHFFFAOYSA-N 0.000 claims description 4
JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 4
YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 claims description 4
QAIPRVGONGVQAS-DUXPYHPUSA-N trans-caffeic acid Chemical compound OC(=O)\C=C\C1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-DUXPYHPUSA-N 0.000 claims description 4
239000007762 w/o emulsion Substances 0.000 claims description 4
239000001993 wax Substances 0.000 claims description 4
QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims description 3
DAKWPKUUDNSNPN-UHFFFAOYSA-N Trimethylolpropane triacrylate Chemical compound C=CC(=O)OCC(CC)(COC(=O)C=C)COC(=O)C=C DAKWPKUUDNSNPN-UHFFFAOYSA-N 0.000 claims description 3
239000002253 acid Substances 0.000 claims description 3
150000007513 acids Chemical class 0.000 claims description 3
239000003963 antioxidant agent Substances 0.000 claims description 3
235000006708 antioxidants Nutrition 0.000 claims description 3
239000003795 chemical substances by application Substances 0.000 claims description 3
125000002887 hydroxy group Chemical group [H]O* 0.000 claims description 3
150000002632 lipids Chemical class 0.000 claims description 3
230000000873 masking effect Effects 0.000 claims description 3
229920002050 silicone resin Polymers 0.000 claims description 3
239000000126 substance Substances 0.000 claims description 3
235000013311 vegetables Nutrition 0.000 claims description 3
229940088594 vitamin Drugs 0.000 claims description 3
229930003231 vitamin Natural products 0.000 claims description 3
235000013343 vitamin Nutrition 0.000 claims description 3
239000011782 vitamin Substances 0.000 claims description 3
QBYIENPQHBMVBV-HFEGYEGKSA-N (2R)-2-hydroxy-2-phenylacetic acid Chemical compound O[C@@H](C(O)=O)c1ccccc1.O[C@@H](C(O)=O)c1ccccc1 QBYIENPQHBMVBV-HFEGYEGKSA-N 0.000 claims description 2
NWCHELUCVWSRRS-SECBINFHSA-N (2r)-2-hydroxy-2-phenylpropanoic acid Chemical compound OC(=O)[C@@](O)(C)C1=CC=CC=C1 NWCHELUCVWSRRS-SECBINFHSA-N 0.000 claims description 2
MUCMKTPAZLSKTL-UHFFFAOYSA-N (3RS)-3-hydroxydodecanoic acid Natural products CCCCCCCCCC(O)CC(O)=O MUCMKTPAZLSKTL-UHFFFAOYSA-N 0.000 claims description 2
JIMKNCCELIMQPR-UHFFFAOYSA-N (7,7-dimethyl-2-methylidene-3-oxo-4-bicyclo[2.2.1]heptanyl)methanesulfonic acid Chemical compound C1CC2(CS(O)(=O)=O)C(=O)C(=C)C1C2(C)C JIMKNCCELIMQPR-UHFFFAOYSA-N 0.000 claims description 2
MEHUJCGAYMDLEL-CABCVRRESA-N (9r,10s)-9,10,16-trihydroxyhexadecanoic acid Chemical compound OCCCCCC[C@H](O)[C@H](O)CCCCCCCC(O)=O MEHUJCGAYMDLEL-CABCVRRESA-N 0.000 claims description 2
125000004178 (C1-C4) alkyl group Chemical group 0.000 claims description 2
ACEAELOMUCBPJP-UHFFFAOYSA-N (E)-3,4,5-trihydroxycinnamic acid Natural products OC(=O)C=CC1=CC(O)=C(O)C(O)=C1 ACEAELOMUCBPJP-UHFFFAOYSA-N 0.000 claims description 2
BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims description 2
BWZVCCNYKMEVEX-UHFFFAOYSA-N 2,4,6-Trimethylpyridine Chemical compound CC1=CC(C)=NC(C)=C1 BWZVCCNYKMEVEX-UHFFFAOYSA-N 0.000 claims description 2
AFENDNXGAFYKQO-UHFFFAOYSA-N 2-hydroxybutyric acid Chemical compound CCC(O)C(O)=O AFENDNXGAFYKQO-UHFFFAOYSA-N 0.000 claims description 2
NYHNVHGFPZAZGA-UHFFFAOYSA-N 2-hydroxyhexanoic acid Chemical compound CCCCC(O)C(O)=O NYHNVHGFPZAZGA-UHFFFAOYSA-N 0.000 claims description 2
BWLBGMIXKSTLSX-UHFFFAOYSA-N 2-hydroxyisobutyric acid Chemical compound CC(C)(O)C(O)=O BWLBGMIXKSTLSX-UHFFFAOYSA-N 0.000 claims description 2
BTJFTHOOADNOOS-UHFFFAOYSA-N 2-hydroxynonanoic acid Chemical compound CCCCCCCC(O)C(O)=O BTJFTHOOADNOOS-UHFFFAOYSA-N 0.000 claims description 2
JRHWHSJDIILJAT-UHFFFAOYSA-N 2-hydroxypentanoic acid Chemical compound CCCC(O)C(O)=O JRHWHSJDIILJAT-UHFFFAOYSA-N 0.000 claims description 2
ZGOZJDITBOCFPV-UHFFFAOYSA-N 5-acetyl-2-hydroxy-4-methylthiophene-3-carbonitrile Chemical compound CC(=O)C=1SC(O)=C(C#N)C=1C ZGOZJDITBOCFPV-UHFFFAOYSA-N 0.000 claims description 2
NAKFRQULMGLXBT-UHFFFAOYSA-N 6-methoxyquinolin-8-ol Chemical compound N1=CC=CC2=CC(OC)=CC(O)=C21 NAKFRQULMGLXBT-UHFFFAOYSA-N 0.000 claims description 2
JMGZEFIQIZZSBH-UHFFFAOYSA-N Bioquercetin Natural products CC1OC(OCC(O)C2OC(OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5)C(O)C2O)C(O)C(O)C1O JMGZEFIQIZZSBH-UHFFFAOYSA-N 0.000 claims description 2
RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 claims description 2
QXKAIJAYHKCRRA-BXXZVTAOSA-N D-ribonic acid Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)C(O)=O QXKAIJAYHKCRRA-BXXZVTAOSA-N 0.000 claims description 2
FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims description 2
102000004190 Enzymes Human genes 0.000 claims description 2
108090000790 Enzymes Proteins 0.000 claims description 2
MEHUJCGAYMDLEL-UHFFFAOYSA-N Ethyl-triacetylaleuritat Natural products OCCCCCCC(O)C(O)CCCCCCCC(O)=O MEHUJCGAYMDLEL-UHFFFAOYSA-N 0.000 claims description 2
241001465754 Metazoa Species 0.000 claims description 2
CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 claims description 2
MSUOLNSQHLHDAS-UHFFFAOYSA-N R-2-Hydroxytetracosanoic acid Natural products CCCCCCCCCCCCCCCCCCCCCCC(O)C(O)=O MSUOLNSQHLHDAS-UHFFFAOYSA-N 0.000 claims description 2
IWYDHOAUDWTVEP-UHFFFAOYSA-N R-2-phenyl-2-hydroxyacetic acid Natural products OC(=O)C(O)C1=CC=CC=C1 IWYDHOAUDWTVEP-UHFFFAOYSA-N 0.000 claims description 2
FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims description 2
239000006096 absorbing agent Substances 0.000 claims description 2
IAJILQKETJEXLJ-RSJOWCBRSA-N aldehydo-D-galacturonic acid Chemical compound O=C[C@H](O)[C@@H](O)[C@@H](O)[C@H](O)C(O)=O IAJILQKETJEXLJ-RSJOWCBRSA-N 0.000 claims description 2
IAJILQKETJEXLJ-QTBDOELSSA-N aldehydo-D-glucuronic acid Chemical compound O=C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)C(O)=O IAJILQKETJEXLJ-QTBDOELSSA-N 0.000 claims description 2
125000002877 alkyl aryl group Chemical group 0.000 claims description 2
SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims description 2
229940061720 alpha hydroxy acid Drugs 0.000 claims description 2
150000001280 alpha hydroxy acids Chemical class 0.000 claims description 2
YDZIJQXINJLRLL-UHFFFAOYSA-N alpha-hydroxydodecanoic acid Natural products CCCCCCCCCCC(O)C(O)=O YDZIJQXINJLRLL-UHFFFAOYSA-N 0.000 claims description 2
BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims description 2
125000003710 aryl alkyl group Chemical group 0.000 claims description 2
125000003118 aryl group Chemical group 0.000 claims description 2
UKXSKSHDVLQNKG-UHFFFAOYSA-N benzilic acid Chemical compound C=1C=CC=CC=1C(O)(C(=O)O)C1=CC=CC=C1 UKXSKSHDVLQNKG-UHFFFAOYSA-N 0.000 claims description 2
150000001277 beta hydroxy acids Chemical class 0.000 claims description 2
229940074360 caffeic acid Drugs 0.000 claims description 2
235000004883 caffeic acid Nutrition 0.000 claims description 2
239000004202 carbamide Substances 0.000 claims description 2
QAIPRVGONGVQAS-UHFFFAOYSA-N cis-caffeic acid Natural products OC(=O)C=CC1=CC=C(O)C(O)=C1 QAIPRVGONGVQAS-UHFFFAOYSA-N 0.000 claims description 2
229960004106 citric acid Drugs 0.000 claims description 2
239000003086 colorant Substances 0.000 claims description 2
IVTMALDHFAHOGL-UHFFFAOYSA-N eriodictyol 7-O-rutinoside Natural products OC1C(O)C(O)C(C)OC1OCC1C(O)C(O)C(O)C(OC=2C=C3C(C(C(O)=C(O3)C=3C=C(O)C(O)=CC=3)=O)=C(O)C=2)O1 IVTMALDHFAHOGL-UHFFFAOYSA-N 0.000 claims description 2
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 2
239000000945 filler Substances 0.000 claims description 2
239000001530 fumaric acid Substances 0.000 claims description 2
235000011087 fumaric acid Nutrition 0.000 claims description 2
239000000174 gluconic acid Substances 0.000 claims description 2
235000012208 gluconic acid Nutrition 0.000 claims description 2
229940097043 glucuronic acid Drugs 0.000 claims description 2
229960004275 glycolic acid Drugs 0.000 claims description 2
229910052736 halogen Inorganic materials 0.000 claims description 2
150000002367 halogens Chemical class 0.000 claims description 2
BEJNERDRQOWKJM-UHFFFAOYSA-N kojic acid Chemical compound OCC1=CC(=O)C(O)=CO1 BEJNERDRQOWKJM-UHFFFAOYSA-N 0.000 claims description 2
229960004705 kojic acid Drugs 0.000 claims description 2
WZNJWVWKTVETCG-UHFFFAOYSA-N kojic acid Natural products OC(=O)C(N)CN1C=CC(=O)C(O)=C1 WZNJWVWKTVETCG-UHFFFAOYSA-N 0.000 claims description 2
150000003951 lactams Chemical group 0.000 claims description 2
239000004310 lactic acid Substances 0.000 claims description 2
235000014655 lactic acid Nutrition 0.000 claims description 2
125000000686 lactone group Chemical group 0.000 claims description 2
239000001630 malic acid Substances 0.000 claims description 2
235000011090 malic acid Nutrition 0.000 claims description 2
229960002510 mandelic acid Drugs 0.000 claims description 2
239000002480 mineral oil Substances 0.000 claims description 2
JMANVNJQNLATNU-UHFFFAOYSA-N oxalonitrile Chemical group N#CC#N JMANVNJQNLATNU-UHFFFAOYSA-N 0.000 claims description 2
FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims description 2
239000002304 perfume Substances 0.000 claims description 2
239000000419 plant extract Substances 0.000 claims description 2
229940107700 pyruvic acid Drugs 0.000 claims description 2
FDRQPMVGJOQVTL-UHFFFAOYSA-N quercetin rutinoside Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 FDRQPMVGJOQVTL-UHFFFAOYSA-N 0.000 claims description 2
229930002330 retinoic acid Natural products 0.000 claims description 2
IKGXIBQEEMLURG-BKUODXTLSA-N rutin Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@@H]1OC[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-BKUODXTLSA-N 0.000 claims description 2
ALABRVAAKCSLSC-UHFFFAOYSA-N rutin Natural products CC1OC(OCC2OC(O)C(O)C(O)C2O)C(O)C(O)C1OC3=C(Oc4cc(O)cc(O)c4C3=O)c5ccc(O)c(O)c5 ALABRVAAKCSLSC-UHFFFAOYSA-N 0.000 claims description 2
235000005493 rutin Nutrition 0.000 claims description 2
229960004555 rutoside Drugs 0.000 claims description 2
229960004889 salicylic acid Drugs 0.000 claims description 2
239000011975 tartaric acid Substances 0.000 claims description 2
235000002906 tartaric acid Nutrition 0.000 claims description 2
VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims description 2
229960001727 tretinoin Drugs 0.000 claims description 2
RGMMREBHCYXQMA-UHFFFAOYSA-N 2-hydroxyheptanoic acid Chemical compound CCCCCC(O)C(O)=O RGMMREBHCYXQMA-UHFFFAOYSA-N 0.000 claims 2
150000002431 hydrogen Chemical group 0.000 claims 2
SBZWTSHAFILOTE-SOUVJXGZSA-N (2R,3S,4S)-leucocyanidin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3[C@H](O)[C@@H]2O)=CC=C(O)C(O)=C1 SBZWTSHAFILOTE-SOUVJXGZSA-N 0.000 claims 1
230000000996 additive effect Effects 0.000 claims 1
229960000448 lactic acid Drugs 0.000 claims 1
229940045136 urea Drugs 0.000 claims 1
238000009826 distribution Methods 0.000 abstract description 9
SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 abstract description 2
210000004877 mucosa Anatomy 0.000 abstract 2
239000013543 active substance Substances 0.000 abstract 1
150000002194 fatty esters Chemical class 0.000 abstract 1
DKGAVHZHDRPRBM-UHFFFAOYSA-N Tert-Butanol Chemical compound CC(C)(C)O DKGAVHZHDRPRBM-UHFFFAOYSA-N 0.000 description 10
210000004209 hair Anatomy 0.000 description 8
230000002335 preservative effect Effects 0.000 description 8
239000000243 solution Substances 0.000 description 8
238000002296 dynamic light scattering Methods 0.000 description 7
229920002521 macromolecule Polymers 0.000 description 7
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 6
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 6
229920000800 acrylic rubber Polymers 0.000 description 5
239000006071 cream Substances 0.000 description 5
235000011187 glycerol Nutrition 0.000 description 5
QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 4
239000002245 particle Substances 0.000 description 4
239000008307 w/o/w-emulsion Substances 0.000 description 4
ATVJXMYDOSMEPO-UHFFFAOYSA-N 3-prop-2-enoxyprop-1-ene Chemical compound C=CCOCC=C ATVJXMYDOSMEPO-UHFFFAOYSA-N 0.000 description 3
DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 description 3
229920002125 Sokalan® Polymers 0.000 description 3
239000010477 apricot oil Substances 0.000 description 3
230000015572 biosynthetic process Effects 0.000 description 3
239000003431 cross linking reagent Substances 0.000 description 3
GVJHHUAWPYXKBD-UHFFFAOYSA-N d-alpha-tocopherol Natural products OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 description 3
239000006185 dispersion Substances 0.000 description 3
230000000694 effects Effects 0.000 description 3
210000000720 eyelash Anatomy 0.000 description 3
239000000499 gel Substances 0.000 description 3
229910052757 nitrogen Inorganic materials 0.000 description 3
239000000047 product Substances 0.000 description 3
210000004761 scalp Anatomy 0.000 description 3
210000003491 skin Anatomy 0.000 description 3
238000007614 solvation Methods 0.000 description 3
238000003756 stirring Methods 0.000 description 3
MYRTYDVEIRVNKP-UHFFFAOYSA-N 1,2-Divinylbenzene Chemical compound C=CC1=CC=CC=C1C=C MYRTYDVEIRVNKP-UHFFFAOYSA-N 0.000 description 2
XHZPRMZZQOIPDS-UHFFFAOYSA-N 2-Methyl-2-[(1-oxo-2-propenyl)amino]-1-propanesulfonic acid Chemical compound OS(=O)(=O)CC(C)(C)NC(=O)C=C XHZPRMZZQOIPDS-UHFFFAOYSA-N 0.000 description 2
HCLJOFJIQIJXHS-UHFFFAOYSA-N 2-[2-[2-(2-prop-2-enoyloxyethoxy)ethoxy]ethoxy]ethyl prop-2-enoate Chemical compound C=CC(=O)OCCOCCOCCOCCOC(=O)C=C HCLJOFJIQIJXHS-UHFFFAOYSA-N 0.000 description 2
208000002874 Acne Vulgaris Diseases 0.000 description 2
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
QIGBRXMKCJKVMJ-UHFFFAOYSA-N Hydroquinone Chemical compound OC1=CC=C(O)C=C1 QIGBRXMKCJKVMJ-UHFFFAOYSA-N 0.000 description 2
208000012641 Pigmentation disease Diseases 0.000 description 2
206010000496 acne Diseases 0.000 description 2
POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 description 2
229910021529 ammonia Inorganic materials 0.000 description 2
229940085262 cetyl dimethicone Drugs 0.000 description 2
238000006243 chemical reaction Methods 0.000 description 2
238000013270 controlled release Methods 0.000 description 2
238000009792 diffusion process Methods 0.000 description 2
239000004615 ingredient Substances 0.000 description 2
239000003999 initiator Substances 0.000 description 2
238000004519 manufacturing process Methods 0.000 description 2
238000002156 mixing Methods 0.000 description 2
230000000379 polymerizing effect Effects 0.000 description 2
239000012429 reaction media Substances 0.000 description 2
238000010992 reflux Methods 0.000 description 2
150000003839 salts Chemical class 0.000 description 2
208000017520 skin disease Diseases 0.000 description 2
235000000346 sugar Nutrition 0.000 description 2
239000004094 surface-active agent Substances 0.000 description 2
XFZJEEAOWLFHDH-UHFFFAOYSA-N (2R,2'R,3R,3'R,4R)-3,3',4',5,7-Pentahydroxyflavan(48)-3,3',4',5,7-pentahydroxyflavan Natural products C=12OC(C=3C=C(O)C(O)=CC=3)C(O)CC2=C(O)C=C(O)C=1C(C1=C(O)C=C(O)C=C1O1)C(O)C1C1=CC=C(O)C(O)=C1 XFZJEEAOWLFHDH-UHFFFAOYSA-N 0.000 description 1
CYIGRWUIQAVBFG-UHFFFAOYSA-N 1,2-bis(2-ethenoxyethoxy)ethane Chemical compound C=COCCOCCOCCOC=C CYIGRWUIQAVBFG-UHFFFAOYSA-N 0.000 description 1
ZIIUUSVHCHPIQD-UHFFFAOYSA-N 2,4,6-trimethyl-N-[3-(trifluoromethyl)phenyl]benzenesulfonamide Chemical compound CC1=CC(C)=CC(C)=C1S(=O)(=O)NC1=CC=CC(C(F)(F)F)=C1 ZIIUUSVHCHPIQD-UHFFFAOYSA-N 0.000 description 1
229920000536 2-Acrylamido-2-methylpropane sulfonic acid Polymers 0.000 description 1
CETWDUZRCINIHU-UHFFFAOYSA-N 2-heptanol Chemical compound CCCCCC(C)O CETWDUZRCINIHU-UHFFFAOYSA-N 0.000 description 1
125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 description 1
NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
206010001488 Aggression Diseases 0.000 description 1
POJWUDADGALRAB-PVQJCKRUSA-N Allantoin Natural products NC(=O)N[C@@H]1NC(=O)NC1=O POJWUDADGALRAB-PVQJCKRUSA-N 0.000 description 1
102000005575 Cellulases Human genes 0.000 description 1
108010084185 Cellulases Proteins 0.000 description 1
102000008186 Collagen Human genes 0.000 description 1
108010035532 Collagen Proteins 0.000 description 1
235000009917 Crataegus X brevipes Nutrition 0.000 description 1
235000013204 Crataegus X haemacarpa Nutrition 0.000 description 1
235000009685 Crataegus X maligna Nutrition 0.000 description 1
235000009444 Crataegus X rubrocarnea Nutrition 0.000 description 1
235000009486 Crataegus bullatus Nutrition 0.000 description 1
235000017181 Crataegus chrysocarpa Nutrition 0.000 description 1
235000009682 Crataegus limnophila Nutrition 0.000 description 1
235000004423 Crataegus monogyna Nutrition 0.000 description 1
240000000171 Crataegus monogyna Species 0.000 description 1
235000002313 Crataegus paludosa Nutrition 0.000 description 1
235000009840 Crataegus x incaedua Nutrition 0.000 description 1
ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
XMSXQFUHVRWGNA-UHFFFAOYSA-N Decamethylcyclopentasiloxane Chemical compound C[Si]1(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O[Si](C)(C)O1 XMSXQFUHVRWGNA-UHFFFAOYSA-N 0.000 description 1
201000004624 Dermatitis Diseases 0.000 description 1
CMBYOWLFQAFZCP-UHFFFAOYSA-N Hexyl dodecanoate Chemical compound CCCCCCCCCCCC(=O)OCCCCCC CMBYOWLFQAFZCP-UHFFFAOYSA-N 0.000 description 1
108010023244 Lactoperoxidase Proteins 0.000 description 1
102000045576 Lactoperoxidases Human genes 0.000 description 1
YIVJZNGAASQVEM-UHFFFAOYSA-N Lauroyl peroxide Chemical compound CCCCCCCCCCCC(=O)OOC(=O)CCCCCCCCCCC YIVJZNGAASQVEM-UHFFFAOYSA-N 0.000 description 1
102000004882 Lipase Human genes 0.000 description 1
108090001060 Lipase Proteins 0.000 description 1
239000004367 Lipase Substances 0.000 description 1
244000062730 Melissa officinalis Species 0.000 description 1
235000010654 Melissa officinalis Nutrition 0.000 description 1
208000008589 Obesity Diseases 0.000 description 1
108091005804 Peptidases Proteins 0.000 description 1
102000015439 Phospholipases Human genes 0.000 description 1
108010064785 Phospholipases Proteins 0.000 description 1
235000008331 Pinus X rigitaeda Nutrition 0.000 description 1
235000011613 Pinus brutia Nutrition 0.000 description 1
241000018646 Pinus brutia Species 0.000 description 1
CWEZAWNPTYBADX-UHFFFAOYSA-N Procyanidin Natural products OC1C(OC2C(O)C(Oc3c2c(O)cc(O)c3C4C(O)C(Oc5cc(O)cc(O)c45)c6ccc(O)c(O)c6)c7ccc(O)c(O)c7)c8c(O)cc(O)cc8OC1c9ccc(O)c(O)c9 CWEZAWNPTYBADX-UHFFFAOYSA-N 0.000 description 1
MOJZMWJRUKIQGL-FWCKPOPSSA-N Procyanidin C2 Natural products O[C@@H]1[C@@H](c2cc(O)c(O)cc2)Oc2c([C@H]3[C@H](O)[C@@H](c4cc(O)c(O)cc4)Oc4c3c(O)cc(O)c4)c(O)cc(O)c2[C@@H]1c1c(O)cc(O)c2c1O[C@@H]([C@H](O)C2)c1cc(O)c(O)cc1 MOJZMWJRUKIQGL-FWCKPOPSSA-N 0.000 description 1
239000004365 Protease Substances 0.000 description 1
108010009736 Protein Hydrolysates Proteins 0.000 description 1
201000004681 Psoriasis Diseases 0.000 description 1
102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
229920002472 Starch Polymers 0.000 description 1
244000269722 Thea sinensis Species 0.000 description 1
240000002657 Thymus vulgaris Species 0.000 description 1
235000007303 Thymus vulgaris Nutrition 0.000 description 1
QYKIQEUNHZKYBP-UHFFFAOYSA-N Vinyl ether Chemical class C=COC=C QYKIQEUNHZKYBP-UHFFFAOYSA-N 0.000 description 1
FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
229930003268 Vitamin C Natural products 0.000 description 1
229930003427 Vitamin E Natural products 0.000 description 1
235000009754 Vitis X bourquina Nutrition 0.000 description 1
235000012333 Vitis X labruscana Nutrition 0.000 description 1
240000006365 Vitis vinifera Species 0.000 description 1
235000014787 Vitis vinifera Nutrition 0.000 description 1
230000016571 aggressive behavior Effects 0.000 description 1
230000032683 aging Effects 0.000 description 1
150000001298 alcohols Chemical class 0.000 description 1
229910052783 alkali metal Inorganic materials 0.000 description 1
229910052784 alkaline earth metal Inorganic materials 0.000 description 1
229960000458 allantoin Drugs 0.000 description 1
150000004716 alpha keto acids Chemical class 0.000 description 1
150000001413 amino acids Chemical class 0.000 description 1
XKMRRTOUMJRJIA-UHFFFAOYSA-N ammonia nh3 Chemical compound N.N XKMRRTOUMJRJIA-UHFFFAOYSA-N 0.000 description 1
230000003078 antioxidant effect Effects 0.000 description 1
208000010668 atopic eczema Diseases 0.000 description 1
230000006399 behavior Effects 0.000 description 1
JQRRFDWXQOQICD-UHFFFAOYSA-N biphenylen-1-ylboronic acid Chemical compound C12=CC=CC=C2C2=C1C=CC=C2B(O)O JQRRFDWXQOQICD-UHFFFAOYSA-N 0.000 description 1
KTUQUZJOVNIKNZ-UHFFFAOYSA-N butan-1-ol;hydrate Chemical compound O.CCCCO KTUQUZJOVNIKNZ-UHFFFAOYSA-N 0.000 description 1
229910052799 carbon Inorganic materials 0.000 description 1
125000004432 carbon atom Chemical group C* 0.000 description 1
229940106189 ceramide Drugs 0.000 description 1
150000001783 ceramides Chemical class 0.000 description 1
229920001436 collagen Polymers 0.000 description 1
230000000052 comparative effect Effects 0.000 description 1
210000002808 connective tissue Anatomy 0.000 description 1
229920006037 cross link polymer Polymers 0.000 description 1
229940086555 cyclomethicone Drugs 0.000 description 1
230000008260 defense mechanism Effects 0.000 description 1
230000001627 detrimental effect Effects 0.000 description 1
SZXQTJUDPRGNJN-UHFFFAOYSA-N dipropylene glycol Chemical compound OCCCOCCCO SZXQTJUDPRGNJN-UHFFFAOYSA-N 0.000 description 1
239000003814 drug Substances 0.000 description 1
238000001035 drying Methods 0.000 description 1
239000003792 electrolyte Substances 0.000 description 1
229940088598 enzyme Drugs 0.000 description 1
235000004626 essential fatty acids Nutrition 0.000 description 1
239000006260 foam Substances 0.000 description 1
238000005187 foaming Methods 0.000 description 1
229940068517 fruit extracts Drugs 0.000 description 1
WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 description 1
239000003349 gelling agent Substances 0.000 description 1
150000002334 glycols Chemical class 0.000 description 1
235000009569 green tea Nutrition 0.000 description 1
210000004247 hand Anatomy 0.000 description 1
230000035876 healing Effects 0.000 description 1
229940100463 hexyl laurate Drugs 0.000 description 1
230000000887 hydrating effect Effects 0.000 description 1
150000001261 hydroxy acids Chemical class 0.000 description 1
239000011261 inert gas Substances 0.000 description 1
239000008384 inner phase Substances 0.000 description 1
150000007529 inorganic bases Chemical class 0.000 description 1
229940057428 lactoperoxidase Drugs 0.000 description 1
238000002356 laser light scattering Methods 0.000 description 1
235000019421 lipase Nutrition 0.000 description 1
239000006210 lotion Substances 0.000 description 1
235000013336 milk Nutrition 0.000 description 1
210000004080 milk Anatomy 0.000 description 1
ZIUHHBKFKCYYJD-UHFFFAOYSA-N n,n'-methylenebisacrylamide Chemical compound C=CC(=O)NCNC(=O)C=C ZIUHHBKFKCYYJD-UHFFFAOYSA-N 0.000 description 1
210000003739 neck Anatomy 0.000 description 1
238000006386 neutralization reaction Methods 0.000 description 1
235000020824 obesity Nutrition 0.000 description 1
150000007530 organic bases Chemical class 0.000 description 1
239000008385 outer phase Substances 0.000 description 1
238000005191 phase separation Methods 0.000 description 1
230000019612 pigmentation Effects 0.000 description 1
239000002798 polar solvent Substances 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
229940100518 polyglyceryl-4 isostearate Drugs 0.000 description 1
229920000151 polyglycol Polymers 0.000 description 1
239000010695 polyglycol Substances 0.000 description 1
238000006116 polymerization reaction Methods 0.000 description 1
239000002244 precipitate Substances 0.000 description 1
238000001556 precipitation Methods 0.000 description 1
HGVVOUNEGQIPMS-UHFFFAOYSA-N procyanidin Chemical compound O1C2=CC(O)=CC(O)=C2C(O)C(O)C1(C=1C=C(O)C(O)=CC=1)OC1CC2=C(O)C=C(O)C=C2OC1C1=CC=C(O)C(O)=C1 HGVVOUNEGQIPMS-UHFFFAOYSA-N 0.000 description 1
229920002414 procyanidin Polymers 0.000 description 1
239000003531 protein hydrolysate Substances 0.000 description 1
102000004169 proteins and genes Human genes 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
230000005855 radiation Effects 0.000 description 1
238000010526 radical polymerization reaction Methods 0.000 description 1
239000011541 reaction mixture Substances 0.000 description 1
229920005989 resin Polymers 0.000 description 1
239000011347 resin Substances 0.000 description 1
230000009759 skin aging Effects 0.000 description 1
238000013112 stability test Methods 0.000 description 1
230000000087 stabilizing effect Effects 0.000 description 1
235000019698 starch Nutrition 0.000 description 1
239000008107 starch Substances 0.000 description 1
150000008163 sugars Chemical class 0.000 description 1
125000000542 sulfonic acid group Chemical group 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
229920001059 synthetic polymer Polymers 0.000 description 1
238000012360 testing method Methods 0.000 description 1
230000001225 therapeutic effect Effects 0.000 description 1
125000003396 thiol group Chemical group [H]S* 0.000 description 1
239000001585 thymus vulgaris Substances 0.000 description 1
210000001519 tissue Anatomy 0.000 description 1
229930003799 tocopherol Natural products 0.000 description 1
235000010384 tocopherol Nutrition 0.000 description 1
229960001295 tocopherol Drugs 0.000 description 1
239000011732 tocopherol Substances 0.000 description 1
VPYJNCGUESNPMV-UHFFFAOYSA-N triallylamine Chemical compound C=CCN(CC=C)CC=C VPYJNCGUESNPMV-UHFFFAOYSA-N 0.000 description 1
235000019155 vitamin A Nutrition 0.000 description 1
239000011719 vitamin A Substances 0.000 description 1
235000019154 vitamin C Nutrition 0.000 description 1
239000011718 vitamin C Substances 0.000 description 1
235000019165 vitamin E Nutrition 0.000 description 1
239000011709 vitamin E Substances 0.000 description 1
229940046009 vitamin E Drugs 0.000 description 1
229940045997 vitamin a Drugs 0.000 description 1
150000003722 vitamin derivatives Chemical class 0.000 description 1
239000000341 volatile oil Substances 0.000 description 1
GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/89—Polysiloxanes
- A61K8/891—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone
- A61K8/894—Polysiloxanes saturated, e.g. dimethicone, phenyl trimethicone, C24-C28 methicone or stearyl dimethicone modified by a polyoxyalkylene group, e.g. cetyl dimethicone copolyol
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/06—Emulsions
- A61K8/066—Multiple emulsions, e.g. water-in-oil-in-water
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8105—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
- A61K8/8111—Homopolymers or copolymers of aliphatic olefines, e.g. polyethylene, polyisobutene; Compositions of derivatives of such polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8135—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by an acyloxy radical of a saturated carboxylic acid, of carbonic acid or of a haloformic acid; Compositions of derivatives of such polymers, e.g. vinyl esters (polyvinylacetate)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8158—Homopolymers or copolymers of amides or imides, e.g. (meth) acrylamide; Compositions of derivatives of such polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8188—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bonds, and at least one being terminated by a bond to sulfur or by a hertocyclic ring containing sulfur; Compositions of derivatives of such polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/16—Emollients or protectives, e.g. against radiation
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/594—Mixtures of polymers

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Birds (AREA)
Epidemiology (AREA)
Chemical & Material Sciences (AREA)
Dermatology (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dispersion Chemistry (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Cosmetics (AREA)

DE69800169T 1997-10-03 1998-09-11 Stabile Wasser-in-Öl-in-Wasser Emulsion und ihre Verwendung als kosmetische und/oder dermatologische Zusammensetzung Expired - Lifetime DE69800169T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9712364A FR2769224B1 (fr)	1997-10-03	1997-10-03	Emulsion e/h/e stable et son utilisation comme composition cosmetique et/ou dermatologique

Publications (2)

Publication Number	Publication Date
DE69800169D1 DE69800169D1 (de)	2000-07-06
DE69800169T2 true DE69800169T2 (de)	2000-09-28

Family

ID=9511811

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69800169T Expired - Lifetime DE69800169T2 (de)	1997-10-03	1998-09-11	Stabile Wasser-in-Öl-in-Wasser Emulsion und ihre Verwendung als kosmetische und/oder dermatologische Zusammensetzung

Country Status (11)

Country	Link
US (1)	US6149900A (ja)
EP (1)	EP0908170B1 (ja)
JP (1)	JP3011696B2 (ja)
KR (1)	KR100298921B1 (ja)
AT (1)	ATE193437T1 (ja)
BR (1)	BR9804154A (ja)
CA (1)	CA2246583C (ja)
DE (1)	DE69800169T2 (ja)
ES (1)	ES2149039T3 (ja)
FR (1)	FR2769224B1 (ja)
PL (1)	PL328936A1 (ja)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2795975B1 (fr) *	1999-07-06	2002-04-19	Oreal	Composition sous forme d'emulsion eau-dans-huile ayant une vitesse de cisaillement evolutive
US6268322B1 (en) *	1999-10-22	2001-07-31	Unilever Home & Personal Care Usa, A Division Of Conopco, Inc.	Dual chamber cleansing system, comprising multiple emulsion
US6290943B1 (en)	1999-10-22	2001-09-18	Unilever Home & Personal Care Usa, Division Of Conopco, Inc.	Stable multiple emulsion composition
JP2003511235A (ja) *	1999-10-22	2003-03-25	ユニリーバー・ナームローゼ・ベンノートシヤープ	安定なマルチプルエマルジョン組成物
US6777450B1 (en)	2000-05-26	2004-08-17	Color Access, Inc.	Water-thin emulsions with low emulsifier levels
JP3893060B2 (ja) *	2000-05-26	2007-03-14	カラーアクセス，インコーポレイティド	低乳化剤複合エマルジョン
FR2810541B1 (fr) *	2000-06-22	2004-02-27	Oreal	Composition sous forme d'emulsion eau-dans-huile ayant une vitesse de cisaillement evolutive
DE10059822A1 (de) *	2000-12-01	2002-06-13	Clariant Gmbh	Saure kosmetische, pharmazeutische und dermatologische Mittel
FR2818542B1 (fr)	2000-12-22	2004-04-30	Oreal	Composition de teinture d'oxydation pour fibres keratiniques a base de polymere amphiphile d'au moins un monomere a insaturation ethylenique a groupement sulfonique et comportant une partie hydrophobe
FR2818543B1 (fr)	2000-12-22	2005-09-02	Oreal	Composition oxydante pour le traitement des matieres keratiniques a base de polymeres amphiphiles d'au moins un monomere a insaturation ethylenique a groupement sulfonique et comportant une partie hydrophobe
NO313934B1 (no) *	2001-03-15	2002-12-30	Pronova Biocare As	Hudpleiemiddel i form av en emulsjon, fremgangsmåte for fremstilling av nevnte hudpleiemiddel, samt anvendelse deav
JP4601031B2 (ja) *	2001-03-16	2010-12-22	株式会社資生堂	Ｗ／ｏ／ｗ型乳化化粧料
EP1252879A1 (en) *	2001-04-27	2002-10-30	Cosmoferm B.V.	Stabilised enzyme compositions
US6986895B2 (en)	2001-09-12	2006-01-17	Unilever Home & Personal Care Usa Division Of Conopco, Inc.	Thickened cosmetic compositions
US20030118620A1 (en) *	2001-09-12	2003-06-26	Unilever Home & Personal Care Usa, Division Of Conopco Inc.	Thickener system for cosmetic compositions
US20050169946A1 (en) *	2002-03-04	2005-08-04	Helene Lannibois	Cosmetic formulation comprising at least two active substances in a multiple emulsion optionally mixed with a single emulsion
US20030215476A1 (en) *	2002-04-12	2003-11-20	L'oreal	Multiple emulsion containing a tensioning agent
US20030232091A1 (en) *	2002-06-17	2003-12-18	Adi Shefer	Stabilized retinol for cosmetic dermatological, and pharmaceutical compositions, and use thereof
WO2003106607A1 (en) *	2002-06-17	2003-12-24	Dow Corning Corporation	Silicone emulsion enzyme systems
FR2835432A1 (fr) *	2002-06-27	2003-08-08	Oreal	Emulsion e/h/e et son utlisation comme composition cosmetique et/ou dermatologique
US20040141930A1 (en) *	2002-10-23	2004-07-22	Frederic Legrand	Oil-in-water oxidizing cream emulsion for treating human keratin fibers
FR2852258B1 (fr) *	2003-03-14	2006-07-21		Emulsions notamment solaires de type eau-dans-huile, et leur procede de preparation
US20050238680A1 (en) *	2004-04-21	2005-10-27	Qing Stella	Personal care compositions that deposit hydrophilic benefit agents
US20050238595A1 (en) *	2004-04-21	2005-10-27	Qing Stella	Personal care compositions that deposit sunless tanning benefit agents
US20050239670A1 (en) *	2004-04-21	2005-10-27	Qing Stella	Personal care compositions that deposit hydrophilic benefit agents
FR2877567B1 (fr) *	2004-11-09	2007-03-02	Oreal	Composition cosmetique et/ou dermatologique contenant un compose d'uree
US20060159716A1 (en) *	2004-12-17	2006-07-20	Agnes Themens	Cosmetic emulsion comprising solid particles, method for preparing cosmetic emulsion, and method of using cosmetic emulsion
KR100537678B1 (ko) *	2005-01-31	2005-12-19	제니코스(주)	Ｗ₁／Ｓｉ／Ｗ₂형 다중 실리콘 유화물 및 이를 포함한화장용 티슈
US8282947B2 (en) *	2005-07-11	2012-10-09	Make-up Art Cosmetics, Inc.	Low viscosity, unstable water-in-silicone emulsion cosmetic compositions and methods of use thereof
US20070166269A1 (en) *	2005-12-01	2007-07-19	L'oreal	Cosmetic composition containing a statistical polymer with a linear chain of ethylenic nature
US20090063334A1 (en) *	2007-08-28	2009-03-05	Alistair Duncan	Business-to-business transaction processing utilizing electronic payment network
JP5465921B2 (ja)	2009-05-15	2014-04-09	出光興産株式会社	生分解性潤滑油組成物
KR102078712B1 (ko) *	2016-06-30	2020-02-19	(주)아모레퍼시픽	안정도가 개선된 다중 유화 조성물
KR102044933B1 (ko)	2016-10-07	2019-11-14	서울대학교 산학협력단	다중에멀젼과 효소처리전분을 이용한 레티놀 안정성 증대 방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2693466B1 (fr) *	1992-07-09	1994-09-16	Oreal	Composition cosmétique sous forme d'émulsion triple eau/huile de silicone/eau gélifiée.
EP0750899A3 (en) *	1995-06-30	1998-05-20	Shiseido Company Limited	An emulsifier or solubilizer which consists of a water soluble amphiphilic polyelectrolyte, and an emulsified composition or a solubilized composition and an emulsified cosmetic or a solubilized cosmetic containing it
FR2742354B1 (fr) *	1995-12-15	1998-01-23	Oreal	Emulsion e/h/e stable contenant un actif cosmetique et/ou dermatologique sensible a l'eau
FR2753625B1 (fr) *	1996-09-20	1998-10-23		Composition cosmetique comprenant un copolymere particulier et utilisation dudit copolymere en cosmetique

1997
- 1997-10-03 FR FR9712364A patent/FR2769224B1/fr not_active Expired - Fee Related
1998
- 1998-09-11 ES ES98402250T patent/ES2149039T3/es not_active Expired - Lifetime
- 1998-09-11 AT AT98402250T patent/ATE193437T1/de not_active IP Right Cessation
- 1998-09-11 EP EP98402250A patent/EP0908170B1/fr not_active Expired - Lifetime
- 1998-09-11 DE DE69800169T patent/DE69800169T2/de not_active Expired - Lifetime
- 1998-10-01 PL PL98328936A patent/PL328936A1/xx unknown
- 1998-10-02 CA CA002246583A patent/CA2246583C/fr not_active Expired - Fee Related
- 1998-10-02 BR BR9804154-1A patent/BR9804154A/pt not_active Application Discontinuation
- 1998-10-02 KR KR1019980041603A patent/KR100298921B1/ko not_active IP Right Cessation
- 1998-10-02 JP JP10281760A patent/JP3011696B2/ja not_active Expired - Fee Related
- 1998-10-05 US US09/166,125 patent/US6149900A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
DE69800169D1 (de)	2000-07-06
FR2769224A1 (fr)	1999-04-09
ATE193437T1 (de)	2000-06-15
US6149900A (en)	2000-11-21
CA2246583A1 (fr)	1999-04-03
CA2246583C (fr)	2005-04-26
BR9804154A (pt)	2000-03-28
KR100298921B1 (ko)	2001-09-06
JP3011696B2 (ja)	2000-02-21
PL328936A1 (en)	1999-04-12
EP0908170A1 (fr)	1999-04-14
KR19990036829A (ko)	1999-05-25
EP0908170B1 (fr)	2000-05-31
ES2149039T3 (es)	2000-10-16
JPH11180824A (ja)	1999-07-06
FR2769224B1 (fr)	2000-01-28

Legal Events

Date	Code	Title	Description
2001-08-09	8364	No opposition during term of opposition

Publication	Publication Date	Title
DE69800169T2 (de)	2000-09-28	Stabile Wasser-in-Öl-in-Wasser Emulsion und ihre Verwendung als kosmetische und/oder dermatologische Zusammensetzung
DE69700055T2 (de)	1999-04-15	Zusammensetzung in Form einer Öl-in-Wasser Emulsion ohne grenzflächenaktiven Stoff zur topischen Anwendung, die ein vernetztes und neutralisiertes Poly(2-acrylamido-2-methylpropan-sulfonsäure)-Polymer enthält
DE69701205T2 (de)	2000-05-31	Kosmetische und/oder dermatalogische säure Zusammensetzung, die eine vernetzte und mindestens 90% neutralisierte Poly-2-acrylamide-2-methylpropane Sulfonsäure enthält
DE69723540T2 (de)	2004-06-09	Zusammensetzung enthaltend ein Protein pflanzlicher und/oder tierischer Abkunft und eine vernetzte Poly(2-Acrylamido 2-Methylpropan Sulfonsäure)
DE69700119T2 (de)	1999-06-24	Kosmetische Verwendung und Präparate einer verzweigten und mindestens auf 90% neutralisierten Polyacrylamidomethylpropansulfonsäure
DE69700180T2 (de)	1999-08-05	Kosmetische und/oder dermatologische Zusammensetzung, die mindestens einen Wirkstoffvorläufer und mindestens eine vernetzte Poly(2-acrylamido-2-methylpropansulfonsäure) enthält
DE69700056T2 (de)	1999-04-15	Ultrafeine Öl-in-Wasser Emulsion, die eine vernetzte, zu mindestens 90% neutralisierte Poly(-2-Acrylamide-2-Methylpropane Sulfonsäure) enthält und Verfahren zur Herstellung
DE69416060T2 (de)	1999-05-27	Stabile Säure Öl-in-Wasser Emulsionen
DE69733687T2 (de)	2006-07-20	Kosmetische zusammensetzung fuer hautregenerierung ohne hautreizung
DE69316177T2 (de)	1998-04-16	Kosmetische oder dermatologische wässrige Dispersion bestehend aus einem Fettsäureester von Zuckern und einem vernetzten Acrylamid-Copolymer
DE69934296T2 (de)	2007-07-05	Verdickend wirkendes latex, verfahren zu dessen herstellung und anwendungen in der kosmetik
DE69600758T2 (de)	1999-03-04	Nanopartikel umhüllt mit einer auf Silikontensid basierten lamellaren Phase sowie ihre Zusammensetzungen
DE69906128T2 (de)	2003-10-30	Reaktionsprodukte von hyaluronsäure und natürlichen aminosäuren sowie deren verwendung in kosmetischen und pharmazeutischen zusammensetzungen
DE60007041T2 (de)	2004-09-30	Zusammensetzung, die einen in einem oxidierenden Medium instabilen Wirkstoff enthält, und Verwendungen insbesondere in der Kosmetik
DE60126860T2 (de)	2007-11-08	Inverslatex basierend auf Squalan oder hydriertem Polyisobuten und diese enthaltende kosmetische Zusammensetzungen, Hautkosmetika, sowie pharmazeutische Zusammensetzungen
DE60127022T2 (de)	2007-11-29	Inverslatex basierend auf Squalan oder hydriertem Polyisobuten und diese enthaltende kosmetische Zusammensetzungen, Hautkosmetika, sowie pharmazeutische Zusammensetzungen
DE69603814T2 (de)	1999-12-09	Verwendung von Ascorbinsäure als Wirkstoff zur Behandlung von Seborrhoe in einer kosmetischen und/oder dermatologischen Zusammensetzung
DE69931567T2 (de)	2007-05-10	Verdickungsmittel und Alkylether eines Polysaccharides enthaltende hydrophile Emulsion, diese enthaltende Zusammensetzungen und ihre Verwendung
US6123960A (en)	2000-09-26	Composition based on lipid vesicles and a cross-linked poly(2-acrylamido-2-methylpropane-sulphonic acid) which is at least 90% neutralized
DE69805435T2 (de)	2003-01-09	Verwendung eines diphenyldimethicongummis gelösst in einem nichtflüchtigen silikon des phenyltrimethicontyps zur herstellung von einem kosmetischen oder pharmazeutischen , insbesondere dermatologischen zusammensetzung die eine fettphase enthält
DE60013708T2 (de)	2005-09-29	Zusammensetzung vom Typ Wasser-in-Öl Emulsion und ihre kosmetische Verwendungen
JPH08283303A (ja)	1996-10-29	高級脂肪酸デキストリンからなる乳化剤、これを含有する乳化組成物および化粧料
DE60016746T2 (de)	2005-12-01	Wässrige trägersysteme für wasserunlösliche aromatische polymere
DE69505177T2 (de)	1999-03-04	Kosmetische und/oder dermatologische Zusammensetzung, insbesondere zur Depigmentierung der Haut, und ihre Verwendungen
JP2656223B2 (ja)	1997-09-24	化粧料及び／又は皮膚科用組成物