DE69734249D1 - Verfahren zur detektion der hk2 polypeptide - Google Patents

Verfahren zur detektion der hk2 polypeptide

Info

Publication number
DE69734249D1
DE69734249D1 DE69734249T DE69734249T DE69734249D1 DE 69734249 D1 DE69734249 D1 DE 69734249D1 DE 69734249 T DE69734249 T DE 69734249T DE 69734249 T DE69734249 T DE 69734249T DE 69734249 D1 DE69734249 D1 DE 69734249D1
Authority
DE
Germany
Prior art keywords
polypeptides
detecting
prostate
antigen
phk2
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69734249T
Other languages
English (en)
Other versions
DE69734249T2 (de
Inventor
Mohammad Saeed Saedi
D Mikolajczyk
Lana Grauer
J Tindall
Y Young
G Klee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hybritech Inc
Mayo Foundation for Medical Education and Research
Original Assignee
Hybritech Inc
Mayo Foundation for Medical Education and Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybritech Inc, Mayo Foundation for Medical Education and Research filed Critical Hybritech Inc
Application granted granted Critical
Publication of DE69734249D1 publication Critical patent/DE69734249D1/de
Publication of DE69734249T2 publication Critical patent/DE69734249T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6445—Kallikreins (3.4.21.34; 3.4.21.35)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433—Serine endopeptidases (3.4.21)
    • G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96455—Kallikrein (3.4.21.34; 3.4.21.35)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69734249T 1996-07-15 1997-07-15 Verfahren zur detektion der hk2 polypeptide Expired - Lifetime DE69734249T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68086896A 1996-07-15 1996-07-15
US680868 1996-07-15
PCT/US1997/012322 WO1998002748A1 (en) 1996-07-15 1997-07-15 Methods to detect hk2 polypeptides

Publications (2)

Publication Number Publication Date
DE69734249D1 true DE69734249D1 (de) 2006-02-02
DE69734249T2 DE69734249T2 (de) 2006-07-13

Family

ID=24732858

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69734249T Expired - Lifetime DE69734249T2 (de) 1996-07-15 1997-07-15 Verfahren zur detektion der hk2 polypeptide

Country Status (7)

Country Link
EP (1) EP0974057B1 (de)
JP (1) JP3955636B2 (de)
AT (1) ATE305140T1 (de)
AU (1) AU736419B2 (de)
CA (1) CA2261019A1 (de)
DE (1) DE69734249T2 (de)
WO (1) WO1998002748A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6479263B1 (en) 1996-11-14 2002-11-12 Baylor College Of Medicine Method for detection of micrometastatic prostate cancer
AU8259798A (en) 1997-06-20 1999-01-04 George G Klee Method for detection of breast cancer
PT1086223E (pt) * 1998-06-01 2009-11-03 Agensys Inc Novos antigénios transmembranares em serpentina expressos em cancros humanos e suas utilizações
US8663600B2 (en) * 2005-02-17 2014-03-04 Diaprost Ab Diagnosis of prostate cancer
EP2598659B1 (de) 2010-07-27 2015-03-11 Genomic Health, Inc. Verfahren zur verwendung von genexpression zur bestimmung der prognose von prostatakrebs

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3684578D1 (de) * 1985-12-17 1992-04-30 Eastern Virginia Medical Autho Monoklonale antikoerper mit bindungsspezifitaet fuer menschliche prostatatumorantigene und methoden fuer ihre verwendung.
US5516639A (en) * 1993-07-22 1996-05-14 Mayo Foundation For Medical Education And Research Antibodies specific for human prostate glandular kallkrein
US6103237A (en) * 1993-07-22 2000-08-15 Hybritech Incorporated Stable variant hK2 polypeptide
AU699748B2 (en) * 1994-05-10 1998-12-10 Hybritech Incorporated Recombinant HK2 polypeptide
GB2302874B (en) * 1995-06-29 1999-11-10 Orion Yhtymae Oy Novel proteins

Also Published As

Publication number Publication date
WO1998002748A1 (en) 1998-01-22
EP0974057B1 (de) 2005-09-21
DE69734249T2 (de) 2006-07-13
JP2001500251A (ja) 2001-01-09
AU3800697A (en) 1998-02-09
EP0974057A1 (de) 2000-01-26
AU736419B2 (en) 2001-07-26
JP3955636B2 (ja) 2007-08-08
CA2261019A1 (en) 1998-01-22
ATE305140T1 (de) 2005-10-15

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