DE69725308D1 - Verfahren und vorrichtung zur inhalation teilchenförmiger medikamente - Google Patents

Verfahren und vorrichtung zur inhalation teilchenförmiger medikamente

Info

Publication number
DE69725308D1
DE69725308D1 DE69725308T DE69725308T DE69725308D1 DE 69725308 D1 DE69725308 D1 DE 69725308D1 DE 69725308 T DE69725308 T DE 69725308T DE 69725308 T DE69725308 T DE 69725308T DE 69725308 D1 DE69725308 D1 DE 69725308D1
Authority
DE
Germany
Prior art keywords
inhalator
inhaling
medicament
medicines
spherical hollow
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69725308T
Other languages
English (en)
Other versions
DE69725308T2 (de
Inventor
Oort Michiel Van
Mark J Sacchetti
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10791297&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69725308(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE69725308D1 publication Critical patent/DE69725308D1/de
Application granted granted Critical
Publication of DE69725308T2 publication Critical patent/DE69725308T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
DE69725308T 1996-03-29 1997-03-25 Verfahren und vorrichtung zur inhalation teilchenförmiger medikamente Revoked DE69725308T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9606677 1996-03-29
GBGB9606677.4A GB9606677D0 (en) 1996-03-29 1996-03-29 Process and device
PCT/EP1997/001560 WO1997036574A1 (en) 1996-03-29 1997-03-25 Process and device for inhalation of particulate medicaments

Publications (2)

Publication Number Publication Date
DE69725308D1 true DE69725308D1 (de) 2003-11-06
DE69725308T2 DE69725308T2 (de) 2004-08-05

Family

ID=10791297

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69725308T Revoked DE69725308T2 (de) 1996-03-29 1997-03-25 Verfahren und vorrichtung zur inhalation teilchenförmiger medikamente

Country Status (12)

Country Link
US (2) US20010018916A1 (de)
EP (1) EP0904056B1 (de)
JP (1) JP2000507862A (de)
AT (1) ATE250922T1 (de)
AU (1) AU724500B2 (de)
CA (1) CA2250217A1 (de)
DE (1) DE69725308T2 (de)
DK (1) DK0904056T3 (de)
ES (1) ES2208889T3 (de)
GB (1) GB9606677D0 (de)
PT (1) PT904056E (de)
WO (1) WO1997036574A1 (de)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6254854B1 (en) 1996-05-24 2001-07-03 The Penn Research Foundation Porous particles for deep lung delivery
US5874064A (en) * 1996-05-24 1999-02-23 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5985309A (en) * 1996-05-24 1999-11-16 Massachusetts Institute Of Technology Preparation of particles for inhalation
US6503480B1 (en) 1997-05-23 2003-01-07 Massachusetts Institute Of Technology Aerodynamically light particles for pulmonary drug delivery
US5855913A (en) * 1997-01-16 1999-01-05 Massachusetts Instite Of Technology Particles incorporating surfactants for pulmonary drug delivery
USRE37053E1 (en) 1996-05-24 2001-02-13 Massachusetts Institute Of Technology Particles incorporating surfactants for pulmonary drug delivery
AU5719798A (en) * 1996-12-31 1998-07-31 Inhale Therapeutic Systems, Inc. Processes for spray drying aqueous suspensions of hydrophobic drugs with hydrophilic excipients and compositions prepared by such processes
ATE239447T1 (de) * 1997-09-29 2003-05-15 Inhale Therapeutic Syst In verneblern verwendbare, stabilisierte zubereitungen
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
CA2231968A1 (en) * 1998-03-11 1999-09-11 Smoke-Stop, A Partnership Consisting Of Art Slutsky Method of producing a nicotine medicament
AP2000001961A0 (en) 1998-04-18 2000-12-31 Glaxo Group Ltd Pharmaceutical aerosol formulation.
GB9808802D0 (en) * 1998-04-24 1998-06-24 Glaxo Group Ltd Pharmaceutical formulations
US6660715B2 (en) 1998-11-19 2003-12-09 Massachusetts Institute Of Technology Nonaqueous solutions and suspensions of macromolecules for pulmonary delivery
MXPA02001323A (es) 2000-05-10 2004-07-16 Alliance Pharma Microgranulos con base fosfolipida para la liberacion de farmaco.
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
FI20002216A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit astman hoitoon
FI20002215A0 (fi) 2000-10-06 2000-10-06 Orion Yhtymae Oyj Yhdistelmäpartikkelit
US6595210B2 (en) 2000-11-27 2003-07-22 Unisia Jecs Corporation Inhalator for administering powder composition
WO2002094238A1 (en) * 2001-05-24 2002-11-28 Alexza Molecular Delivery Corporation Delivery of anti-migraine compounds through an inhalation route
US20030051728A1 (en) 2001-06-05 2003-03-20 Lloyd Peter M. Method and device for delivering a physiologically active compound
US20070122353A1 (en) 2001-05-24 2007-05-31 Hale Ron L Drug condensation aerosols and kits
CA2446904A1 (en) 2001-05-24 2003-04-03 Alexza Molecular Delivery Corporation Delivery of drug esters through an inhalation route
DE60230502D1 (de) * 2001-05-24 2009-02-05 Alexza Pharmaceuticals Inc Verabreichung von antimigränemitteln durch inhalation
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
WO2003015747A1 (en) 2001-08-13 2003-02-27 Genomed, Llc Method to treat pulmonary hypoplasia in the newborn
WO2003037303A1 (en) 2001-11-01 2003-05-08 Nektar Therapeutics Spray drying methods and compositions thereof
EP1458361A4 (de) * 2001-11-20 2007-04-25 Advanced Inhalation Res Inc Zusammensetzungen zur abgabe von produkten mit anhaltender wirkung
ATE508735T1 (de) 2001-12-19 2011-05-15 Novartis Ag Pulmonale verabreichung von aminoglykosiden
EP1531798B1 (de) * 2002-03-20 2012-06-06 Civitas Therapeutics, Inc. Pulmonale abgabe von levodopa
AU2003243191B2 (en) 2002-05-02 2007-09-20 President And Fellows Of Harvard College Formulations limiting spread of pulmonary infections
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US7185647B2 (en) * 2002-08-16 2007-03-06 Schering Corporation Determination of smoothness of canisters containing inhalable medicaments
US20050044164A1 (en) * 2002-12-23 2005-02-24 O'farrell Robert Mobile data and software update system and method
US20040224674A1 (en) * 2003-04-07 2004-11-11 O'farrell Robert System and method for context sensitive mobile data and software update
CA2522231A1 (en) * 2003-04-14 2004-10-21 Vectura Ltd Pharmaceutical compositions comprising apomorphine for pulmonary inhalation
US20050207983A1 (en) 2004-03-05 2005-09-22 Pulmatrix, Inc. Formulations decreasing particle exhalation
US8627821B2 (en) 2005-01-10 2014-01-14 Pulmatrix, Inc. Method and device for decreasing contamination
MX2009008582A (es) 2007-02-11 2009-10-30 Map Pharmaceuticals Inc Metodo para la administracion terapeutica de dihidroergotamina para permitir un rapido alivio de la migraña mientras se minimiza el perfil de efectos secundarios.
US20080202627A1 (en) * 2007-02-23 2008-08-28 Mas Gregory V Dosing System and Method
US20080216828A1 (en) 2007-03-09 2008-09-11 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
MX2011000405A (es) * 2008-07-18 2011-03-04 Prosonix Ltd Proceso para mejorar la cristalinidad.
WO2010063286A2 (en) 2008-12-04 2010-06-10 Nordicaryan Aps A hand-held inhaler
BRPI1011721B1 (pt) 2009-03-26 2021-11-16 Pulmatrix, Inc Formulações em pó seco inaláveis compreendendo sal de cátion de metal divalente e métodos para tratar doenças pulmonares
US9433588B2 (en) * 2009-11-09 2016-09-06 Virginia Commonwealth Univeristy Delivery of submicrometer and nanometer aerosols to the lungs using hygroscopic excipients or dual stream nasal delivery
WO2012030645A1 (en) 2010-08-30 2012-03-08 Pulmatrix, Inc. Respirably dry powder comprising calcium lactate, sodium chloride and leucine
WO2012030664A1 (en) 2010-08-30 2012-03-08 Pulmatrix, Inc. Dry powder formulations and methods for treating pulmonary diseases
KR101798691B1 (ko) * 2010-09-06 2017-11-16 키에시 파르마슈티시 엣스. 피. 에이. 계량된-투여량 흡입기 및 계량된-투여량 흡입기의 사용 방법
AU2011308865B2 (en) 2010-09-29 2017-01-05 Pulmatrix, Inc. Monovalent metal cation dry powders for inhalation
US9433576B2 (en) 2010-09-29 2016-09-06 Pulmatrix, Inc. Cationic dry powders
JP2014518270A (ja) 2011-06-27 2014-07-28 ボード・オブ・リージエンツ，ザ・ユニバーシテイ・オブ・テキサス・システム トロイダル医薬製剤
CN104487075A (zh) 2012-02-29 2015-04-01 普马特里克斯公司 可吸入干粉剂
MX2015013845A (es) 2013-04-01 2016-05-09 Pulmatrix Inc Polvos secos de tiotropio.
AU2015338717B2 (en) 2014-10-31 2018-12-20 Glaxosmithkline Intellectual Property Development Limited Powder formulation
GB2573297A (en) * 2018-04-30 2019-11-06 Mexichem Fluor Sa De Cv Pharmaceutical composition
EP3563894B1 (de) * 2018-05-04 2021-12-22 Boehringer Ingelheim International GmbH Zerstäuber und behälter
WO2019236649A1 (en) * 2018-06-07 2019-12-12 3M Innovative Properties Company Fluticasone and vilanterol formulation and inhaler

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4161516A (en) * 1975-07-25 1979-07-17 Fisons Limited Composition for treating airway disease
US4147766A (en) * 1976-06-09 1979-04-03 Armour Pharmaceutical Company Macrospherical particles of anti-perspirants
EP0072046B1 (de) * 1981-07-24 1986-01-15 FISONS plc Inhalierbare Arzneimittel, Verfahren zu deren Herstellung und pharmazeutische Formulierungen diese enthaltend
GB2146531B (en) * 1983-09-15 1987-04-29 Stc Plc Controlled release system
US4818542A (en) * 1983-11-14 1989-04-04 The University Of Kentucky Research Foundation Porous microspheres for drug delivery and methods for making same
US4865789A (en) * 1983-11-14 1989-09-12 Akzo Nv Method for making porous structures
US4690825A (en) * 1985-10-04 1987-09-01 Advanced Polymer Systems, Inc. Method for delivering an active ingredient by controlled time release utilizing a novel delivery vehicle which can be prepared by a process utilizing the active ingredient as a porogen
GB8601100D0 (en) * 1986-01-17 1986-02-19 Cosmas Damian Ltd Drug delivery system
US4741872A (en) * 1986-05-16 1988-05-03 The University Of Kentucky Research Foundation Preparation of biodegradable microspheres useful as carriers for macromolecules
GB8713263D0 (en) * 1987-06-05 1987-07-08 Unilever Plc Spheroidal silica
JPH0762054B2 (ja) * 1987-10-13 1995-07-05 倉敷紡績株式会社 架橋重合体粒子
US4855144A (en) * 1987-10-23 1989-08-08 Advanced Polymer Systems Synthetic melanin aggregates
US4937081A (en) * 1988-01-14 1990-06-26 Daicel Chemical Industries Ltd. Process for producing porous, spherical particles
US5023080A (en) * 1988-06-17 1991-06-11 Basic Bio Systems, Inc. Time release protein
MX9702357A (es) * 1994-09-29 1997-06-28 Andaris Ltd Microparticulas secadas por aspersion como vehiculos terapeuticos.

Also Published As

Publication number Publication date
ES2208889T3 (es) 2004-06-16
EP0904056A1 (de) 1999-03-31
AU2292197A (en) 1997-10-22
US20030005927A1 (en) 2003-01-09
AU724500B2 (en) 2000-09-21
US20010018916A1 (en) 2001-09-06
DK0904056T3 (da) 2004-01-19
DE69725308T2 (de) 2004-08-05
JP2000507862A (ja) 2000-06-27
WO1997036574A1 (en) 1997-10-09
GB9606677D0 (en) 1996-06-05
CA2250217A1 (en) 1997-10-09
PT904056E (pt) 2004-02-27
ATE250922T1 (de) 2003-10-15
EP0904056B1 (de) 2003-10-01

Similar Documents

Publication Publication Date Title
DE69725308D1 (de) Verfahren und vorrichtung zur inhalation teilchenförmiger medikamente
PT1019022E (pt) Microparticulas perfuradas e metodos de utilizacao
DE69927139T2 (de) Lungendosiersystem
AT384552B (de) Inhalationsgeraet zur dosierung und verteilung von festkoerpern in die atemluft
MX9700034A (es) Formulacion para la aplicacion por inhalacion.
ATE545442T1 (de) Medizinische vorrichtung zur inhalation von aerosolisiertem arzneimittel mit heliox
MY125534A (en) Systems and methods for aerosolizing pharmaceutical formulations
AU3400501A (en) Improvements in or relating to the delivery of oral drugs
SCHEUCH et al. An approach to deposition and clearance measurements in human airways
GB9806462D0 (en) Improved compositions for inhalation
DE69826532D1 (de) Vorrichtung zur organisation des kombinierten gebrauchs von lokalen aerosolen und oralen medikamenten
RU2012363C1 (ru) Устройство в.а.старцева для насыщения воздуха лекарственными веществами
DE29501527U1 (de) Vorrichtung zur Erzeugung inhalierbarer Wirkstoffpartikel
SE9402383L (sv) Förfarande och anordning för att införa en aktiv substans till en persons andningssystem

Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation