DE69706355T2 - Alkylendiamin-Derivate als Arzneimittel zur Behandlung von Geschwüren und Hemmung von Helicobacter pylori - Google Patents
Alkylendiamin-Derivate als Arzneimittel zur Behandlung von Geschwüren und Hemmung von Helicobacter pyloriInfo
- Publication number
- DE69706355T2 DE69706355T2 DE69706355T DE69706355T DE69706355T2 DE 69706355 T2 DE69706355 T2 DE 69706355T2 DE 69706355 T DE69706355 T DE 69706355T DE 69706355 T DE69706355 T DE 69706355T DE 69706355 T2 DE69706355 T2 DE 69706355T2
- Authority
- DE
- Germany
- Prior art keywords
- group
- lower alkyl
- ulcers
- chem
- expressed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 125000005263 alkylenediamine group Chemical group 0.000 title abstract 3
- 208000025865 Ulcer Diseases 0.000 title abstract 2
- 231100000397 ulcer Toxicity 0.000 title abstract 2
- 241000590002 Helicobacter pylori Species 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 229940037467 helicobacter pylori Drugs 0.000 title 1
- 230000005764 inhibitory process Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000002350 geranyl group Chemical group [H]C([*])([H])/C([H])=C(C([H])([H])[H])/C([H])([H])C([H])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 2
- 125000001844 prenyl group Chemical group [H]C([*])([H])C([H])=C(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 2
- 241000589989 Helicobacter Species 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Chemical group 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/125—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
- C07D295/13—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12219596 | 1996-04-18 | ||
| JP27887196 | 1996-09-30 | ||
| JP01205697A JP4150435B2 (ja) | 1996-04-18 | 1997-01-06 | アルキレンジアミン誘導体及び抗潰瘍剤、抗菌剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69706355D1 DE69706355D1 (de) | 2001-10-04 |
| DE69706355T2 true DE69706355T2 (de) | 2002-06-13 |
Family
ID=27279684
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69706355T Expired - Lifetime DE69706355T2 (de) | 1996-04-18 | 1997-04-18 | Alkylendiamin-Derivate als Arzneimittel zur Behandlung von Geschwüren und Hemmung von Helicobacter pylori |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5814634A (de) |
| EP (1) | EP0802196B1 (de) |
| JP (1) | JP4150435B2 (de) |
| KR (1) | KR19980069747A (de) |
| AT (1) | ATE204867T1 (de) |
| CA (1) | CA2202958A1 (de) |
| DE (1) | DE69706355T2 (de) |
| TW (1) | TW399044B (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1131290B1 (de) | 1998-11-20 | 2008-02-20 | F. Hoffmann-La Roche Ag | Piperidin ccr-3 rezeptor-hemmer |
| WO2000076556A2 (en) * | 1999-06-11 | 2000-12-21 | Neorx Corporation | High dose radionuclide complexes for bone marrow suppression |
| US7094885B2 (en) | 1999-07-11 | 2006-08-22 | Neorx Corporation | Skeletal-targeted radiation to treat bone-associated pathologies |
| WO2002062398A2 (en) | 2001-01-08 | 2002-08-15 | Neorx Corporation | Radioactively labelled conjugates of phosphonates |
| JP2005516933A (ja) | 2001-12-13 | 2005-06-09 | ダウ グローバル テクノロジーズ インコーポレイティド | 放射性医薬による骨髄炎の治療 |
| CN103012318B (zh) * | 2012-11-25 | 2014-12-10 | 大理学院 | 氟苄基取代哌嗪类化合物及其制备和医药用途 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH01168678A (ja) * | 1987-12-24 | 1989-07-04 | Teikoku Chem Ind Corp Ltd | ベンズアミド誘導体 |
| JP2700910B2 (ja) * | 1989-02-07 | 1998-01-21 | 帝国化学産業株式会社 | ベンズアミド誘導体 |
| JP2843871B2 (ja) * | 1990-05-14 | 1999-01-06 | 本田技研工業株式会社 | 内燃エンジンの燃焼異常検出装置 |
| JPH05239005A (ja) * | 1992-02-28 | 1993-09-17 | Kitsuen Kagaku Kenkyu Zaidan | Ｎ−（２−アミノエチル）ベンズアミド類およびその新規中間体 |
| IT1266582B1 (it) * | 1993-07-30 | 1997-01-09 | Recordati Chem Pharm | Derivati (di)azacicloesanici e diazacicloeptanici |
-
1997
- 1997-01-06 JP JP01205697A patent/JP4150435B2/ja not_active Expired - Fee Related
- 1997-04-15 TW TW086104833A patent/TW399044B/zh not_active IP Right Cessation
- 1997-04-17 CA CA002202958A patent/CA2202958A1/en not_active Abandoned
- 1997-04-17 US US08/842,891 patent/US5814634A/en not_active Expired - Lifetime
- 1997-04-18 AT AT97302666T patent/ATE204867T1/de not_active IP Right Cessation
- 1997-04-18 EP EP97302666A patent/EP0802196B1/de not_active Expired - Lifetime
- 1997-04-18 DE DE69706355T patent/DE69706355T2/de not_active Expired - Lifetime
- 1997-04-18 KR KR1019970015041A patent/KR19980069747A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JPH10152471A (ja) | 1998-06-09 |
| CA2202958A1 (en) | 1997-10-18 |
| TW399044B (en) | 2000-07-21 |
| ATE204867T1 (de) | 2001-09-15 |
| DE69706355D1 (de) | 2001-10-04 |
| KR19980069747A (ko) | 1998-10-26 |
| EP0802196B1 (de) | 2001-08-29 |
| US5814634A (en) | 1998-09-29 |
| AU1898797A (en) | 1997-10-23 |
| EP0802196A1 (de) | 1997-10-22 |
| AU711954B2 (en) | 1999-10-28 |
| JP4150435B2 (ja) | 2008-09-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE82966T1 (de) | Pyridincarboxamid-derivate und ihre verwendung als fungizides mittel. | |
| DE69738245D1 (de) | 1,2-Diphenylpyrrol-Derivate, ihre Herstellung und therapeutische Verwendung | |
| DE69627042D1 (de) | Isocumarinderivate und deren verwendung in medikamenten | |
| DE69432973D1 (de) | Verwendung von thiazolidindionen zur behandlung von atherosklerose und essstörungen | |
| ATE58535T1 (de) | 3-vinyl- und 3-ethinyl-beta-carbolinderivate, ihre herstellung und ihre verwendung als arzneimittel. | |
| DE69222459T2 (de) | Thiazolidindionderivate, ihre Herstellung und Anwendung | |
| DE69706355T2 (de) | Alkylendiamin-Derivate als Arzneimittel zur Behandlung von Geschwüren und Hemmung von Helicobacter pylori | |
| DE69810373D1 (de) | Pyrrolidin Derivate, Anti-ulcus und Antibakterielle Arzneimittel | |
| DE69708484D1 (de) | Pyridinderivate,als Arzneimittel zur Behandlung von Geschwüren und als antibakterielle Mittel | |
| DE69824476D1 (de) | Alkylene-Derivat, Anti-ulcus und antibakterielle Arzneimittel | |
| DE69807138T2 (de) | Benzoamid-Derivat, antiulcus und antibakterielle Mittel | |
| ATE219065T1 (de) | Arylpiperidin- und arylpiperazin-derivate und sie enthaltende arzneimittel | |
| NO302365B1 (no) | Alkylderivater av trazodon med CNS-aktivitet | |
| NO893039L (no) | Bruk av imidazopyrazol-derivater som analgesiske og antiinflammatoriske midler. | |
| DK0795326T3 (da) | Okulærtensionssænkende middel | |
| DE69706012T2 (de) | N-Acylpiperazinderivat, antibakterielle und gegen Geschwüre wirksame Medikamente | |
| ATE283269T1 (de) | 5-(heteroaryl)alkyl)-3-oxo-pyrido(1,2- a)benzimidazol-4-carboxamid (pbi) derivate zur behandlung von störungen des zentralen nervensystems | |
| ATE212842T1 (de) | Quinoxalin-derivate zur behandlung von tinnitus |