DE69703417T2 - Ausgerichtete Peptid-Anordnung und ein rationelles und schnelles Verfahren zum Nachweis einer Bindung oder einer Wechselwirkungsstelle eines Proteins mittels deren - Google Patents

Ausgerichtete Peptid-Anordnung und ein rationelles und schnelles Verfahren zum Nachweis einer Bindung oder einer Wechselwirkungsstelle eines Proteins mittels deren

Info

Publication number
DE69703417T2
DE69703417T2 DE1997603417 DE69703417T DE69703417T2 DE 69703417 T2 DE69703417 T2 DE 69703417T2 DE 1997603417 DE1997603417 DE 1997603417 DE 69703417 T DE69703417 T DE 69703417T DE 69703417 T2 DE69703417 T2 DE 69703417T2
Authority
DE
Germany
Prior art keywords
rational
protein
binding
detection
interaction site
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE1997603417
Other languages
English (en)
Other versions
DE69703417D1 (de
Inventor
Johji Miwa
Shahid Saeed Siddiqui
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NEC Corp
Original Assignee
NEC Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NEC Corp filed Critical NEC Corp
Publication of DE69703417D1 publication Critical patent/DE69703417D1/de
Application granted granted Critical
Publication of DE69703417T2 publication Critical patent/DE69703417T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/047—Simultaneous synthesis of different peptide species; Peptide libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43536—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms
    • C07K14/4354—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from worms from nematodes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6878—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids in eptitope analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/43504—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates
    • G01N2333/43526—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms
    • G01N2333/4353—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from invertebrates from worms from nematodes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
DE1997603417 1996-07-12 1997-07-11 Ausgerichtete Peptid-Anordnung und ein rationelles und schnelles Verfahren zum Nachweis einer Bindung oder einer Wechselwirkungsstelle eines Proteins mittels deren Expired - Fee Related DE69703417T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18314096A JPH1025299A (ja) 1996-07-12 1996-07-12 整列ペプチド、及びそれを用いたタンパク質の結合・相互作用部位検出方法

Publications (2)

Publication Number Publication Date
DE69703417D1 DE69703417D1 (de) 2000-12-07
DE69703417T2 true DE69703417T2 (de) 2001-04-19

Family

ID=16130510

Family Applications (1)

Application Number Title Priority Date Filing Date
DE1997603417 Expired - Fee Related DE69703417T2 (de) 1996-07-12 1997-07-11 Ausgerichtete Peptid-Anordnung und ein rationelles und schnelles Verfahren zum Nachweis einer Bindung oder einer Wechselwirkungsstelle eines Proteins mittels deren

Country Status (3)

Country Link
EP (1) EP0818467B1 (de)
JP (1) JPH1025299A (de)
DE (1) DE69703417T2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999039210A1 (en) * 1998-01-29 1999-08-05 Miller, Samuel High density arrays for proteome analysis and methods and compositions therefor
ATE393912T1 (de) 1998-02-04 2008-05-15 Invitrogen Corp Microarrays und ihre verwendungen
CA2365431A1 (en) * 1999-03-10 2000-09-14 Hui Ge Universal protein array system
AU773957C (en) * 1999-05-14 2005-08-25 Georges, Elias Ph.D. Protein-protein interactions and methods for identifying interacting proteins and the amino acid sequence at the site of interaction
EP1684077A1 (de) * 1999-05-14 2006-07-26 McGill University Verfahren zur Identifizierung von Modulatoren wechselwirkender Proteine
KR20000071894A (ko) * 1999-08-19 2000-12-05 김선영 단백질칩 및 이를 이용한 다목적 자동화 진단시스템
AU1630501A (en) * 1999-10-08 2001-04-23 Superarray, Inc. Compositions and methods for detecting protein modification and enzymatic activity
AU5951201A (en) 2000-05-04 2001-11-12 Univ Yale High density protein arrays for screening of protein activity
DE60120713T2 (de) * 2000-08-15 2007-06-06 Discerna Ltd. Funktionelles protein array
US6980674B2 (en) 2000-09-01 2005-12-27 Large Scale Proteomics Corp. Reference database
US6539102B1 (en) 2000-09-01 2003-03-25 Large Scale Proteomics Reference database
EP1360490B1 (de) 2001-01-23 2011-12-21 President and Fellows of Harvard College Nukleinsäure-programmierbare protein-arrays
WO2002090923A2 (en) * 2001-05-03 2002-11-14 Sigma-Genosys, Ltd. Methods for assembling protein microarrays
US8148141B2 (en) 2001-05-07 2012-04-03 Hipep Laboratories Peptide-immobilized substrate and method for measuring target protein
JP2006512080A (ja) * 2002-12-31 2006-04-13 ロディ ファーマ，インコーポレイティド バインディングザイムアレイ及びハイスループットプロテオミクス方法
US7736909B2 (en) 2003-01-09 2010-06-15 Board Of Regents, The University Of Texas System Methods and compositions comprising capture agents
KR100690948B1 (ko) 2004-06-17 2007-03-09 한국과학기술원 대장균의 외막 단백질을 이용한 목적 단백질의 미생물표면발현 방법
KR100784261B1 (ko) 2006-01-02 2007-12-11 한국과학기술원 탄저균의 포자외막 단백질을 이용한 목적단백질의 미생물표면발현방법
US8178316B2 (en) 2006-06-29 2012-05-15 President And Fellows Of Harvard College Evaluating proteins
KR20120122869A (ko) 2009-06-02 2012-11-07 보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템 신경변성 질환을 갖는 대상에서 항체에 의해 인식되는 소분자의 확인법
EP2488543A1 (de) 2009-10-16 2012-08-22 The Board of Regents of The University of Texas System Zusammensetzungen und verfahren zur herstellung von cyclischen peptoidbibliotheken

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2422492A (en) * 1991-08-07 1993-03-02 H & N Instruments, Inc. Synthesis of chain chemical compounds

Also Published As

Publication number Publication date
EP0818467A2 (de) 1998-01-14
DE69703417D1 (de) 2000-12-07
EP0818467B1 (de) 2000-11-02
EP0818467A3 (de) 1998-04-08
JPH1025299A (ja) 1998-01-27

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee