DE69635886D1 - Exzitatorisch wirkende Aminosäurederivate - Google Patents

Exzitatorisch wirkende Aminosäurederivate

Info

Publication number: DE69635886D1
Authority: DE; Germany
Prior art keywords: amino acid; acid derivatives; excitatory amino; excitatory; derivatives
Prior art date: 1995-11-16
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69635886T

Other languages

English (en)

Other versions

DE69635886T2 (de

Inventor

James Allen Monn

Matthew John Valli

Steven Marc Massey

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Eli Lilly and Co

Original Assignee

Eli Lilly and Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-16

Filing date

1996-11-14

Publication date

2006-05-04

1996-03-15 Priority claimed from GBGB9605434.1A external-priority patent/GB9605434D0/en

1996-11-14 Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co

2006-05-04 Application granted granted Critical

2006-05-04 Publication of DE69635886D1 publication Critical patent/DE69635886D1/de

2006-10-19 Publication of DE69635886T2 publication Critical patent/DE69635886T2/de

2016-11-15 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

DE69635886T 1995-11-16 1996-11-14 Exzitatorisch wirkende Aminosäurederivate Expired - Lifetime DE69635886T2 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US686495P	1995-11-16	1995-11-16
US6864		1995-11-16
GBGB9605434.1A GB9605434D0 (en)	1996-03-15	1996-03-15	Excitatory amino acid derivatives
GB9605434		1996-03-15

Publications (2)

Publication Number	Publication Date
DE69635886D1 true DE69635886D1 (de)	2006-05-04
DE69635886T2 DE69635886T2 (de)	2006-10-19

Family

ID=26308935

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE69635886T Expired - Lifetime DE69635886T2 (de)	1995-11-16	1996-11-14	Exzitatorisch wirkende Aminosäurederivate

Country Status (22)

Country	Link
EP (1)	EP0774461B1 (de)
KR (1)	KR19990067598A (de)
CN (1)	CN1202167A (de)
AR (2)	AR004602A1 (de)
AT (1)	ATE319685T1 (de)
AU (1)	AU703409B2 (de)
BR (1)	BR9611511A (de)
CA (1)	CA2237910C (de)
CO (1)	CO4770955A1 (de)
CZ (1)	CZ150198A3 (de)
DE (1)	DE69635886T2 (de)
EA (1)	EA001617B1 (de)
ES (1)	ES2258771T3 (de)
HU (1)	HUP9903459A3 (de)
IL (1)	IL124487A (de)
NO (1)	NO982202D0 (de)
NZ (1)	NZ323205A (de)
PE (1)	PE17798A1 (de)
PL (1)	PL326695A1 (de)
TR (1)	TR199800877T2 (de)
WO (1)	WO1997018199A1 (de)
YU (1)	YU60796A (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998032436A1 (en) *	1997-01-29	1998-07-30	Eli Lilly And Company	Treatment for premenstrual dysphoric disorder
US6825211B1 (en)	1997-07-18	2004-11-30	Georgetown University	Bicyclic metabotropic glutamate receptor ligands
WO1999003822A1 (en) *	1997-07-18	1999-01-28	Georgetown University	Bicyclic metabotropic glutamate receptor ligands
DE19801646A1 (de) *	1998-01-17	1999-07-22	Bayer Ag	Substituierte alpha,beta-annellierte Butyrolactone
DE19801647A1 (de) *	1998-01-17	1999-07-22	Bayer Ag	Substituierte beta,gamma-annellierte Lactone
DE19801648A1 (de) *	1998-01-17	1999-07-22	Bayer Ag	alpha-Substituierte Lactone
DE19801636A1 (de) *	1998-01-17	1999-07-22	Bayer Ag	Substituierte bicyclische Lactone
GB2355982A (en) *	1999-11-03	2001-05-09	Lilly Co Eli	Heterocyclic amino acids
TW200833674A (en) *	2002-06-11	2008-08-16	Lilly Co Eli	Prodrugs of excitatory amino acids
DK2370377T3 (en) *	2008-11-14	2016-01-04	Dsm Fine Chem Austria Gmbh	METHOD FOR PRODUCING cyclopropane derivatives
WO2010111080A2 (en)	2009-03-27	2010-09-30	Eli Lilly And Company	Optimized treatment of schizophrenia
US8735397B2 (en) *	2010-03-29	2014-05-27	Vanderbilt University	Method for treating schizophrenia and related diseases
PT2721012T (pt)	2011-06-17	2016-07-27	Lilly Co Eli	Derivados do ácido biciclo(3.1.0)hexano-2,6¿dicarboxílico como agonista do recetor mglu2
AR089718A1 (es)	2012-02-01	2014-09-10	Lilly Co Eli	AGONISTAS DE mGlu2/3
DK3431106T3 (da)	2014-01-21	2021-03-15	Janssen Pharmaceutica Nv	Kombinationer omfattende positive allosteriske modulatorer eller orthosteriske agonister af metabotrop glutamaterg subtype 2-receptor og anvendelse af disse
ES2860298T3 (es)	2014-01-21	2021-10-04	Janssen Pharmaceutica Nv	Combinaciones que comprenden moduladores alostéricos positivos del receptor glutamatérgico metabotrópico de subtipo 2 y su uso

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2572842A (en) *	1947-08-05	1951-10-30	Du Pont	The n-carboanhydride of 2-amino-4, 6, 6-trimethylheptanoic acid and polymers therefrom
US4536330A (en) *	1982-09-23	1985-08-20	International Flavors & Fragrances Inc.	1-Hydroxymethyl-2-acyl cyclopropane derivatives and esters and cyclic condensation products thereof, organoleptic uses of same and processes for preparing same
CA2195779A1 (en) *	1994-08-12	1996-02-22	David Reed Helton	Composition and method for protection against drug dependency
PL182285B1 (pl) *	1994-08-12	2001-12-31	Lilly Co Eli	Syntetyczne aminokwasy oraz ich estry i srodki farmaceutyczne je zawierajace PL PL PL PL PL PL PL
PT776201E (pt) *	1994-08-12	2002-03-28	Lilly Co Eli	Composicao e metodo para tratar a ansiedade

1996
- 1996-11-12 TR TR1998/00877T patent/TR199800877T2/xx unknown
- 1996-11-12 BR BR9611511A patent/BR9611511A/pt active Search and Examination
- 1996-11-12 AU AU77279/96A patent/AU703409B2/en not_active Ceased
- 1996-11-12 NZ NZ323205A patent/NZ323205A/xx unknown
- 1996-11-12 KR KR1019980703624A patent/KR19990067598A/ko not_active Application Discontinuation
- 1996-11-12 HU HU9903459A patent/HUP9903459A3/hu unknown
- 1996-11-12 EA EA199800377A patent/EA001617B1/ru not_active IP Right Cessation
- 1996-11-12 CN CN96198396A patent/CN1202167A/zh active Pending
- 1996-11-12 PL PL96326695A patent/PL326695A1/xx unknown
- 1996-11-12 CA CA002237910A patent/CA2237910C/en not_active Expired - Fee Related
- 1996-11-12 WO PCT/US1996/018112 patent/WO1997018199A1/en not_active Application Discontinuation
- 1996-11-12 CZ CZ981501A patent/CZ150198A3/cs unknown
- 1996-11-12 IL IL12448796A patent/IL124487A/xx not_active IP Right Cessation
- 1996-11-13 CO CO96059738A patent/CO4770955A1/es unknown
- 1996-11-13 PE PE1996000813A patent/PE17798A1/es not_active Application Discontinuation
- 1996-11-14 DE DE69635886T patent/DE69635886T2/de not_active Expired - Lifetime
- 1996-11-14 ES ES96308216T patent/ES2258771T3/es not_active Expired - Lifetime
- 1996-11-14 EP EP96308216A patent/EP0774461B1/de not_active Expired - Lifetime
- 1996-11-14 AT AT96308216T patent/ATE319685T1/de not_active IP Right Cessation
- 1996-11-15 AR ARP960105204A patent/AR004602A1/es unknown
- 1996-11-15 YU YU60796A patent/YU60796A/sh unknown
- 1996-11-15 AR ARP960105205A patent/AR006748A1/es unknown
1998
- 1998-05-14 NO NO982202A patent/NO982202D0/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
IL124487A (en)	2001-01-11
EP0774461B1 (de)	2006-03-08
CA2237910A1 (en)	1997-05-22
KR19990067598A (ko)	1999-08-25
NO982202L (no)	1998-05-14
YU60796A (sh)	1998-12-23
ES2258771T3 (es)	2006-09-01
EA199800377A1 (ru)	1998-10-29
ATE319685T1 (de)	2006-03-15
CA2237910C (en)	2005-12-27
IL124487A0 (en)	1998-12-06
CN1202167A (zh)	1998-12-16
NO982202D0 (no)	1998-05-14
NZ323205A (en)	1999-06-29
PL326695A1 (en)	1998-10-26
HUP9903459A2 (hu)	2001-04-28
AU703409B2 (en)	1999-03-25
EA001617B1 (ru)	2001-06-25
WO1997018199A1 (en)	1997-05-22
TR199800877T2 (xx)	1998-09-21
AU7727996A (en)	1997-06-05
EP0774461A1 (de)	1997-05-21
CZ150198A3 (cs)	1998-10-14
DE69635886T2 (de)	2006-10-19
CO4770955A1 (es)	1999-04-30
AR004602A1 (es)	1998-12-16
PE17798A1 (es)	1998-04-18
HUP9903459A3 (en)	2001-08-28
AR006748A1 (es)	1999-09-29
BR9611511A (pt)	1999-05-04

Legal Events

Date	Code	Title	Description
2007-03-29	8364	No opposition during term of opposition
2010-05-20	8328	Change in the person/name/address of the agent	Representative=s name: KROHER, STROBEL RECHTS- UND PATENTANWAELTE, 80336
2011-06-16	8328	Change in the person/name/address of the agent	Representative=s name: DR. SCHOEN & PARTNER, 80336 MUENCHEN

Publication	Publication Date	Title
ATE211131T1 (de)	2002-01-15	Arylsulfonylaminohydroxamsäurederivate
DK0696577T3 (da)	1999-06-23	Syntetiske excitatoriske aminosyrer
DE69522717D1 (de)	2001-10-18	Chinazolinderivate
DE69611361T2 (de)	2001-04-26	Chinazolin-derivate
DE69610698D1 (de)	2000-11-23	Chinazolin-derivate
ATE199150T1 (de)	2001-02-15	Diphenylmethylenpiperidin-derivate
DE69635886D1 (de)	2006-05-04	Exzitatorisch wirkende Aminosäurederivate
NO950477D0 (no)	1995-02-09	Aminosyrederivater
BR9611509A (pt)	1999-03-02	Antagonistas de receptores de aminoácidos excitativos
DE69606053D1 (de)	2000-02-10	Modifizierte fluorsulfonsäure
DE69604999D1 (de)	1999-12-09	Brückenverbinder
DE69601527T2 (de)	1999-06-17	Pyrrolylbenzimidazol-Derivate
BR9610239A (pt)	1999-06-15	Proteínas de fusão-alérgeno-xcd32
ATA100695A (de)	1998-03-15	Prothrombin-derivate
BR9609671A (pt)	1999-07-06	Amino uracilas substituídas
ATE240307T1 (de)	2003-05-15	Diarylalkenylamin-derivate
ATE202093T1 (de)	2001-06-15	4-amino-benzoylguanidin-derivate
DE59610106D1 (de)	2003-03-13	Fluorbenzylether-Derivate
ATE177102T1 (de)	1999-03-15	Chromanderivate
DE69624122D1 (de)	2002-11-07	Aza-anthracyclinone-derivate
ATE202088T1 (de)	2001-06-15	4-mercapto-benzoylguanidin-derivate
DE69620514T2 (de)	2002-11-28	5-aminoflavon-derivate
SE9503923D0 (sv)	1995-11-07	New amino acid derivatives
SE9504349D0 (sv)	1995-12-05	New amino acid derivatives
SE9502487D0 (sv)	1995-07-06	New amino acid derivatives