DE69634697D1 - Kationische polyacrylate und poly(alkyl)acrylate oder die entsprechende acrylamide zur verwendung in synthetischen transfektions-systemen - Google Patents
Kationische polyacrylate und poly(alkyl)acrylate oder die entsprechende acrylamide zur verwendung in synthetischen transfektions-systemenInfo
- Publication number
- DE69634697D1 DE69634697D1 DE69634697T DE69634697T DE69634697D1 DE 69634697 D1 DE69634697 D1 DE 69634697D1 DE 69634697 T DE69634697 T DE 69634697T DE 69634697 T DE69634697 T DE 69634697T DE 69634697 D1 DE69634697 D1 DE 69634697D1
- Authority
- DE
- Germany
- Prior art keywords
- poly
- alkyl
- acrylamides
- acrylates
- cationic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US605923 | 1990-10-30 | ||
| EP95202891 | 1995-10-25 | ||
| EP95202891 | 1995-10-25 | ||
| US592395P | 1995-10-27 | 1995-10-27 | |
| PCT/NL1996/000416 WO1997015680A1 (en) | 1995-10-25 | 1996-10-25 | Cationic polyacrylates and poly(alkyl) acrylates or the corresponding acrylamides for use in synthetic transfection or blocking systems |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69634697D1 true DE69634697D1 (de) | 2005-06-09 |
| DE69634697T2 DE69634697T2 (de) | 2006-05-04 |
Family
ID=26139739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69634697T Expired - Fee Related DE69634697T2 (de) | 1995-10-25 | 1996-10-25 | Kationische polyacrylate und poly(alkyl)acrylate oder die entsprechende acrylamide zur verwendung in synthetischen transfektions-systemen |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5985573A (de) |
| EP (1) | EP0859857B1 (de) |
| JP (1) | JP3957084B2 (de) |
| AT (1) | ATE294875T1 (de) |
| AU (1) | AU7342296A (de) |
| DE (1) | DE69634697T2 (de) |
| ES (1) | ES2242198T3 (de) |
| WO (1) | WO1997015680A1 (de) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0965583A1 (de) * | 1998-06-15 | 1999-12-22 | Transgene S.A. | Zum Einschleusen von Wirkstoffen in Zellen geeignete Polyamin-Verbindungen und diese enthaltende Zusammensetzungen |
| EP0965584A3 (de) * | 1998-06-15 | 2003-12-17 | Transgene S.A. | Zum Einschleusen von Wirkstoffen in Zellen geeignete Polyamin-Verbindungen und diese enthaltende Zusammensetzungen |
| US20050153926A1 (en) * | 1998-12-04 | 2005-07-14 | Adams Christopher P. | Method for the immobilization of oligonucleotides |
| EP1022340A1 (de) * | 1999-01-21 | 2000-07-26 | OctoPlus B.V. | Stabilisierung von Zusammensetzungen die nicht-virale nukeinsäure-Transfer-Zusammensetzungen enthalten |
| WO2004030455A1 (en) * | 2002-10-03 | 2004-04-15 | Agroshield, Llc | Polymers for protecting materials from damage |
| WO2004087228A1 (ja) * | 2003-03-28 | 2004-10-14 | Japan Science And Technology Agency | 生体適合性と温度応答性を併せ持つ高分子 |
| JP5153072B2 (ja) * | 2003-04-18 | 2013-02-27 | 独立行政法人国立循環器病研究センター | ベクター |
| JP4718766B2 (ja) * | 2003-06-03 | 2011-07-06 | テルモ株式会社 | 血液フィルター |
| EP1505089B1 (de) * | 2003-08-07 | 2006-01-11 | OctoPlus Technologies B.V. | Kationisches (Alkyl)acrylamid, hiervon abgeleitetes Polymeres sowie dieses enthaltendes Transfektions-System |
| US20090123468A1 (en) | 2003-10-24 | 2009-05-14 | Gencia Corporation | Transducible polypeptides for modifying metabolism |
| CA2543257C (en) | 2003-10-24 | 2013-12-31 | Gencia Corporation | Methods and compositions for delivering polynucleotides |
| US8507277B2 (en) | 2003-10-24 | 2013-08-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides |
| US8062891B2 (en) | 2003-10-24 | 2011-11-22 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to plants |
| US8133733B2 (en) | 2003-10-24 | 2012-03-13 | Gencia Corporation | Nonviral vectors for delivering polynucleotides to target tissues |
| US7786194B2 (en) * | 2004-04-02 | 2010-08-31 | Agroshield, Llc | Compositions and methods for protecting materials from damage |
| RU2363493C2 (ru) * | 2004-04-05 | 2009-08-10 | Басф Акциенгезельшафт | Содержащие действующие вещества полимерные частицы |
| EP1595534A1 (de) * | 2004-05-13 | 2005-11-16 | Universiteit Utrecht Holding B.V. | Gelzusammensetzung enthaltend geladenepolymere |
| DE102004059792A1 (de) * | 2004-12-10 | 2006-06-14 | Röhm GmbH & Co. KG | Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Nukleinsäure-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform |
| US20060211004A1 (en) | 2005-02-15 | 2006-09-21 | Ilsley Diane D | Methods and compositions for determining non-specific cytotoxicity of a transfection agent |
| DE102007056488A1 (de) | 2007-11-22 | 2009-07-23 | Biontex Laboratories Gmbh | Steigerung von Transfektionseffizienzen nicht-viraler Genliefersysteme durch Blockierung des angeborenen Immunsystems |
| EP2212425A2 (de) | 2007-11-22 | 2010-08-04 | Biontex Laboratories Gmbh | Verbesserung von transfektionsergebnissen nicht-viraler genliefersysteme durch beeinflussung des angeborenen immunsystems |
| DE102008016275A1 (de) | 2008-03-28 | 2009-11-19 | Biontex Laboratories Gmbh | Verbesserung von Transfektionsergebnissen nicht-viraler Genliefersysteme durch Blockierung des angeborenen Immunsystems |
| DE102008023913A1 (de) | 2008-05-16 | 2009-11-19 | Biontex Laboratories Gmbh | Verbesserung von Transfektionsergebnissen nicht-viraler Genliefersysteme durch Beeinflussung des angeborenen Immunsystems |
| WO2010150089A1 (en) * | 2009-06-26 | 2010-12-29 | Cedars-Sinai Medical Center | Highly efficient systems for delivery of nucleic acids |
| US8678201B2 (en) * | 2010-06-04 | 2014-03-25 | Goodrich Corporation | Aircraft potable water system |
| EP2522689A1 (de) | 2011-05-13 | 2012-11-14 | Universität Bayreuth | Nicht virale Transfektionssysteme |
| US9283072B2 (en) | 2012-07-25 | 2016-03-15 | W. L. Gore & Associates, Inc. | Everting transcatheter valve and methods |
| US9144492B2 (en) | 2012-12-19 | 2015-09-29 | W. L. Gore & Associates, Inc. | Truncated leaflet for prosthetic heart valves, preformed valve |
| US9968443B2 (en) | 2012-12-19 | 2018-05-15 | W. L. Gore & Associates, Inc. | Vertical coaptation zone in a planar portion of prosthetic heart valve leaflet |
| US9101469B2 (en) | 2012-12-19 | 2015-08-11 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with leaflet shelving |
| US9827094B2 (en) | 2014-09-15 | 2017-11-28 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with retention elements |
| JP6875601B2 (ja) | 2017-09-27 | 2021-05-26 | ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティドＷ．Ｌ． Ｇｏｒｅ ＆ Ａｓｓｏｃｉａｔｅｓ， Ｉｎｃｏｒｐｏｒａｔｅｄ | リーフレットが機械的にカップリングされた人工弁 |
| EP4364696A2 (de) | 2017-09-27 | 2024-05-08 | Edwards Lifesciences Corporation | Klappenprothese mit expandierbarem rahmen sowie zugehörige systeme und verfahren |
| US11154397B2 (en) | 2017-10-31 | 2021-10-26 | W. L. Gore & Associates, Inc. | Jacket for surgical heart valve |
| JP7052032B2 (ja) | 2017-10-31 | 2022-04-11 | ダブリュ．エル．ゴア アンド アソシエイツ，インコーポレイティド | 組織内方成長を促進する医療用弁及び弁膜 |
| US11497601B2 (en) | 2019-03-01 | 2022-11-15 | W. L. Gore & Associates, Inc. | Telescoping prosthetic valve with retention element |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5286634A (en) * | 1989-09-28 | 1994-02-15 | Stadler Joan K | Synergistic method for host cell transformation |
| JPH0463597A (ja) * | 1990-06-29 | 1992-02-28 | W R Grace & Co | 細胞への遺伝子導入法およびそれに用いる細胞固定板 |
| DE4139001A1 (de) * | 1991-11-27 | 1993-06-03 | Boehringer Mannheim Gmbh | Verfahren zur einschleusung von nukleinsaeuren in zellen |
-
1996
- 1996-10-25 ES ES96935575T patent/ES2242198T3/es not_active Expired - Lifetime
- 1996-10-25 WO PCT/NL1996/000416 patent/WO1997015680A1/en active IP Right Grant
- 1996-10-25 AT AT96935575T patent/ATE294875T1/de not_active IP Right Cessation
- 1996-10-25 DE DE69634697T patent/DE69634697T2/de not_active Expired - Fee Related
- 1996-10-25 AU AU73422/96A patent/AU7342296A/en not_active Abandoned
- 1996-10-25 EP EP96935575A patent/EP0859857B1/de not_active Expired - Lifetime
- 1996-10-25 JP JP51649797A patent/JP3957084B2/ja not_active Expired - Fee Related
-
1998
- 1998-04-27 US US09/067,276 patent/US5985573A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| EP0859857B1 (de) | 2005-05-04 |
| US5985573A (en) | 1999-11-16 |
| ES2242198T3 (es) | 2005-11-01 |
| WO1997015680A1 (en) | 1997-05-01 |
| JP2001508641A (ja) | 2001-07-03 |
| DE69634697T2 (de) | 2006-05-04 |
| AU7342296A (en) | 1997-05-15 |
| JP3957084B2 (ja) | 2007-08-08 |
| EP0859857A1 (de) | 1998-08-26 |
| ATE294875T1 (de) | 2005-05-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |