DE69621591D1 - Medikament welches Protein C aktivierendes Peptid enthält - Google Patents
Medikament welches Protein C aktivierendes Peptid enthältInfo
- Publication number
- DE69621591D1 DE69621591D1 DE69621591T DE69621591T DE69621591D1 DE 69621591 D1 DE69621591 D1 DE 69621591D1 DE 69621591 T DE69621591 T DE 69621591T DE 69621591 T DE69621591 T DE 69621591T DE 69621591 D1 DE69621591 D1 DE 69621591D1
- Authority
- DE
- Germany
- Prior art keywords
- containing protein
- medicament containing
- activating peptide
- protein
- pharmaceutical preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/33—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6464—Protein C (3.4.21.69)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/375,777 US5571786A (en) | 1990-08-16 | 1995-01-20 | Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation |
PCT/EP1996/000126 WO1996022108A1 (en) | 1995-01-20 | 1996-01-12 | The use of activated protein c for preparing a pharmaceutical preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69621591D1 true DE69621591D1 (de) | 2002-07-11 |
DE69621591T2 DE69621591T2 (de) | 2003-01-16 |
Family
ID=23482293
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69621591T Expired - Fee Related DE69621591T2 (de) | 1995-01-20 | 1996-01-12 | Medikament welches Protein C aktivierendes Peptid enthält |
Country Status (9)
Country | Link |
---|---|
US (1) | US5571786A (de) |
EP (1) | EP0804228B1 (de) |
JP (1) | JP3330953B2 (de) |
AT (2) | AT409822B (de) |
CA (1) | CA2209931A1 (de) |
DE (1) | DE69621591T2 (de) |
DK (1) | DK0804228T3 (de) |
ES (1) | ES2177755T3 (de) |
WO (1) | WO1996022108A1 (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0975775B1 (de) * | 1997-04-23 | 2004-03-17 | Vlaams Interuniversitair Instituut voor Biotechnologie | Regulationssystem für induzierbare expression von gene mit lambda-ähnlichen promotoren |
US6953568B1 (en) * | 1998-08-25 | 2005-10-11 | Oklahoma Medical Research Foundation | Targeting of molecules to large vessel endothelium using EPCR |
JP2002542148A (ja) * | 1998-12-21 | 2002-12-10 | イーライ・リリー・アンド・カンパニー | 敗血症の処置のための組み合わせ療法 |
EP1353702A2 (de) * | 2000-05-22 | 2003-10-22 | The Johns Hopkins University | Genmanipulation der gefässtransplantat zur resistenz gegen erkrankungen |
WO2002100445A1 (en) * | 2001-06-13 | 2002-12-19 | The University Of Sydney | Treatment and composition for wound healing |
JP2004535461A (ja) * | 2001-07-19 | 2004-11-25 | ディーエムアイ バイオサイエンシズ インコーポレイテッド | プロテインcの不活性化を抑制するための銅キレート剤の使用 |
KR101188292B1 (ko) | 2002-11-27 | 2012-10-09 | 디엠아이 바이오사이언시스, 인크 | 인산화 증가로 인한 질병 및 증상의 치료방법 |
HUE045997T2 (hu) | 2012-05-31 | 2020-01-28 | Univ Kinki | Hatóanyag rákellenes szer által okozott perifériás neuropátiás fájdalom megelõzésére és/vagy kezelésére |
KR102068010B1 (ko) | 2012-07-04 | 2020-01-20 | 제트제트 바이오테크 엘엘씨 | 염증성 피부 질환의 치료 |
CN106573040B (zh) | 2014-04-16 | 2021-07-06 | Zz生物技术有限责任公司 | 治疗异常皮肤瘢痕形成 |
US11497795B2 (en) | 2018-09-28 | 2022-11-15 | Asahi Kasei Pharma Corporation | Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU185926B (en) * | 1979-09-27 | 1985-04-28 | Agostne Kahan | Process for preparing water soluble derivatives of non-steroid antiinflammatory compositions and pharmaceutical compositins containing such derivatives |
GB8319538D0 (en) * | 1983-07-20 | 1983-08-24 | Beecham Group Plc | Compounds |
US4658830A (en) * | 1984-08-08 | 1987-04-21 | Survival Technology, Inc. | Method and apparatus for initiating reperfusion treatment by an unattended individual undergoing heart attack symptoms |
US4902614A (en) * | 1984-12-03 | 1990-02-20 | Teijin Limited | Monoclonal antibody to human protein C |
US4775624A (en) * | 1985-02-08 | 1988-10-04 | Eli Lilly And Company | Vectors and compounds for expression of human protein C |
US4849403A (en) * | 1985-05-29 | 1989-07-18 | Pentapharm Ag | Protein C activator, methods of preparation and use thereof |
US4908314A (en) * | 1987-07-02 | 1990-03-13 | American National Red Cross | Protein C activator |
US5084274A (en) * | 1987-11-17 | 1992-01-28 | Scripps Clinic And Research Foundation | Inhibition of arterial thrombotic occlusion or thromboembolism |
US5009889A (en) * | 1987-12-31 | 1991-04-23 | Oklahoma Medical Research Foundation | Treatment of dysfunctional vascular endothelium using activated protein C |
JP2739050B2 (ja) * | 1988-01-28 | 1998-04-08 | ヘキスト薬品工業株式会社 | 抗血液凝固剤 |
DE3804600A1 (de) * | 1988-02-13 | 1989-08-24 | Basf Ag | Mischung aus einer thrombolytisch wirkenden und einer antithrombotischen substanz |
US5093117A (en) * | 1989-01-24 | 1992-03-03 | Baxter International Inc. | Compositions and method for the treatment or prophylaxis of sepsis or septic shock |
JP2774156B2 (ja) * | 1989-09-05 | 1998-07-09 | 帝人株式会社 | ヒトプロテインcおよび/または活性化ヒトプロテインc様活性を有する蛋白 |
AT402260B (de) * | 1990-08-16 | 1997-03-25 | Immuno Ag | Protein c-hältige pharmazeutische präparation |
-
1995
- 1995-01-20 US US08/375,777 patent/US5571786A/en not_active Expired - Fee Related
-
1996
- 1996-01-12 AT AT0901196A patent/AT409822B/de not_active IP Right Cessation
- 1996-01-12 JP JP52188996A patent/JP3330953B2/ja not_active Expired - Fee Related
- 1996-01-12 DK DK96901265T patent/DK0804228T3/da active
- 1996-01-12 AT AT96901265T patent/ATE218368T1/de not_active IP Right Cessation
- 1996-01-12 DE DE69621591T patent/DE69621591T2/de not_active Expired - Fee Related
- 1996-01-12 EP EP96901265A patent/EP0804228B1/de not_active Expired - Lifetime
- 1996-01-12 CA CA002209931A patent/CA2209931A1/en not_active Abandoned
- 1996-01-12 WO PCT/EP1996/000126 patent/WO1996022108A1/en active IP Right Grant
- 1996-01-12 ES ES96901265T patent/ES2177755T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0804228B1 (de) | 2002-06-05 |
EP0804228A1 (de) | 1997-11-05 |
US5571786A (en) | 1996-11-05 |
JP3330953B2 (ja) | 2002-10-07 |
DK0804228T3 (da) | 2002-09-23 |
DE69621591T2 (de) | 2003-01-16 |
CA2209931A1 (en) | 1996-07-25 |
ATE218368T1 (de) | 2002-06-15 |
WO1996022108A1 (en) | 1996-07-25 |
ATA901196A (de) | 2002-04-15 |
ES2177755T3 (es) | 2002-12-16 |
JPH11502508A (ja) | 1999-03-02 |
AT409822B (de) | 2002-11-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |