DE69601525D1 - Verfahren zur herstellung von dicarbonsäurechlorid - Google Patents

Verfahren zur herstellung von dicarbonsäurechlorid

Info

Publication number: DE69601525D1
Authority: DE; Germany
Prior art keywords: producing; acid chloride; dicarbonic acid; triiodo; amino
Prior art date: 1995-05-23
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69601525T

Other languages

English (en)

Other versions

DE69601525T2 (de

Inventor

Marina Mauro

Carlo Viscardi

Massimo Gagna

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bracco Imaging SpA

Original Assignee

FRUCTAMINE SpA MOZZO IT

Fructamine SpA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-05-23

Filing date

1996-05-17

Publication date

1999-03-25

1995-05-23 Priority claimed from ITMI951044A external-priority patent/IT1274546B/it

1995-08-04 Priority claimed from IT95RM000550 external-priority patent/IT1281320B1/it

1996-05-17 Application filed by FRUCTAMINE SpA MOZZO IT, Fructamine SpA filed Critical FRUCTAMINE SpA MOZZO IT

1999-03-25 Application granted granted Critical

1999-03-25 Publication of DE69601525D1 publication Critical patent/DE69601525D1/de

1999-06-24 Publication of DE69601525T2 publication Critical patent/DE69601525T2/de

2016-05-18 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

ZFTFAPZRGNKQPU-UHFFFAOYSA-N dicarbonic acid Chemical compound OC(=O)OC(O)=O ZFTFAPZRGNKQPU-UHFFFAOYSA-N 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
DKPFZGUDAPQIHT-UHFFFAOYSA-N butyl acetate Chemical compound CCCCOC(C)=O DKPFZGUDAPQIHT-UHFFFAOYSA-N 0.000 abstract 2
FYSNRJHAOHDILO-UHFFFAOYSA-N thionyl chloride Chemical compound ClS(Cl)=O FYSNRJHAOHDILO-UHFFFAOYSA-N 0.000 abstract 2
UOCLXMDMGBRAIB-UHFFFAOYSA-N 1,1,1-trichloroethane Chemical compound CC(Cl)(Cl)Cl UOCLXMDMGBRAIB-UHFFFAOYSA-N 0.000 abstract 1
FBJVWRITWDYUAC-UHFFFAOYSA-N 5-amino-2,4,6-triiodobenzene-1,3-dicarbonyl chloride Chemical compound NC1=C(I)C(C(Cl)=O)=C(I)C(C(Cl)=O)=C1I FBJVWRITWDYUAC-UHFFFAOYSA-N 0.000 abstract 1
JEZJSNULLBSYHV-UHFFFAOYSA-N 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid Chemical compound NC1=C(I)C(C(O)=O)=C(I)C(C(O)=O)=C1I JEZJSNULLBSYHV-UHFFFAOYSA-N 0.000 abstract 1
150000004945 aromatic hydrocarbons Chemical class 0.000 abstract 1
230000003197 catalytic effect Effects 0.000 abstract 1
SBZXBUIDTXKZTM-UHFFFAOYSA-N diglyme Chemical compound COCCOCCOC SBZXBUIDTXKZTM-UHFFFAOYSA-N 0.000 abstract 1
229930195733 hydrocarbon Natural products 0.000 abstract 1
150000002430 hydrocarbons Chemical class 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
239000002904 solvent Substances 0.000 abstract 1
150000003512 tertiary amines Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
- C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
- C07C381/10—Compounds containing sulfur atoms doubly-bound to nitrogen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

DE69601525T 1995-05-23 1996-05-17 Verfahren zur herstellung von dicarbonsäurechlorid Expired - Lifetime DE69601525T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
ITMI951044A IT1274546B (it)	1995-05-23	1995-05-23	Processo per la preparazione del dicloruro dell'acido 5-ammino-2,4,- 6-triiodoisoftalico
IT95RM000550 IT1281320B1 (it)	1995-08-04	1995-08-04	Procedimento di preparazione di dicloruro dell'acido 5-ammino-2,4,6- triiodo-1,3-benzendicarbossilico per reazione dell'acido
PCT/EP1996/002103 WO1996037459A1 (en)	1995-05-23	1996-05-17	Process for the preparation of a dicarboxylic acid dichloride

Publications (2)

Publication Number	Publication Date
DE69601525D1 true DE69601525D1 (de)	1999-03-25
DE69601525T2 DE69601525T2 (de)	1999-06-24

Family

ID=26331277

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DE69601525T Expired - Lifetime DE69601525T2 (de)	1995-05-23	1996-05-17	Verfahren zur herstellung von dicarbonsäurechlorid
DE0773924T Pending DE773924T1 (de)	1995-05-23	1996-05-17	Verfahren zur herstellung von dicarbonsäurechlorid

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
DE0773924T Pending DE773924T1 (de)	1995-05-23	1996-05-17	Verfahren zur herstellung von dicarbonsäurechlorid

Country Status (22)

Country	Link
US (1)	US5616795A (de)
EP (1)	EP0773924B1 (de)
JP (1)	JP4012566B2 (de)
KR (1)	KR100255914B1 (de)
CN (1)	CN1157367C (de)
AT (1)	ATE176663T1 (de)
AU (1)	AU702895B2 (de)
BR (1)	BR9606488A (de)
CA (1)	CA2195636C (de)
CZ (1)	CZ290345B6 (de)
DE (2)	DE69601525T2 (de)
DK (1)	DK0773924T3 (de)
ES (1)	ES2103252T3 (de)
GR (1)	GR970300027T1 (de)
HU (1)	HU216548B (de)
IL (1)	IL118359A (de)
MX (1)	MX9700548A (de)
NO (1)	NO313696B1 (de)
PL (1)	PL182447B1 (de)
SI (1)	SI9620012A (de)
SK (1)	SK8797A3 (de)
WO (1)	WO1996037459A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1271107B (it) *	1994-11-29	1997-05-26	Zambon Spa	Processo per la preparazione di un intermedio utile nella sintesi di composti organici
IT1292037B1 (it) *	1997-05-30	1999-01-25	Bracco Spa	Processo per la preparazione di 5-(acetil 62,3-diidrossipropil)- ammino)-n,n'-bis(2,3-diidrossipropil)-2,4,6-triiodo-1,3-benzen-
US7968745B2 (en)	2005-12-19	2011-06-28	Ge Healthcare As	Purification process of iodixanol
GB0717189D0 (en) *	2007-09-04	2007-10-17	Syngenta Participations Ag	Novel processes and compounds
WO2009091758A1 (en)	2008-01-14	2009-07-23	Mallinckrodt Inc.	Process for the preparation of iosimenol
EP2230227A1 (de)	2009-03-20	2010-09-22	Bracco Imaging S.p.A	Verfahren zur Herstellung von aromatischen Trijodid-Carboxyl- Derivaten
EP2243767A1 (de)	2009-04-21	2010-10-27	Bracco Imaging S.p.A	Verfahren zur Iodierung aromatischer Verbindungen
US7999134B2 (en)	2009-07-21	2011-08-16	Ge Healthcare As	Crystallization of iodixanol using milling
US7999135B2 (en)	2009-07-21	2011-08-16	Ge Healthcare As	Crystallization of iodixanol using ultrasound
CN102725249B (zh)	2009-11-26	2014-12-10	好利安中国控股有限公司	碘克沙醇的制备和纯化
EP2394984A1 (de)	2010-06-10	2011-12-14	Bracco Imaging S.p.A	Verfahren zur Iodinierung von Phenol-Derivaten
WO2014090650A1 (en)	2012-12-11	2014-06-19	Bracco Imaging Spa	Continuous process for the preparation of (s)-2-acetyloxypropionic acid chloride
PL3066071T3 (pl)	2013-11-05	2018-09-28	Bracco Imaging S.P.A	Sposób otrzymywania jopamidolu
BR112016027507B1 (pt)	2014-06-10	2020-11-24	Bracco Imaging Spa	método para a preparação de ácido (s)-2-acetiloxipropiônico e seus derivados
CN104230731B (zh) *	2014-09-24	2016-01-20	武汉理工大学	造影剂中间体三碘异酞酰氯的制备方法
US10836710B2 (en)	2016-12-05	2020-11-17	Bracco Imaging Spa	Mechanochemical synthesis of radiographic agents intermediates

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH608189A5 (de) *	1974-12-13	1978-12-29	Savac Ag
IT1193211B (it) *	1979-08-09	1988-06-15	Bracco Ind Chimica Spa	Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono
IT1207226B (it) *	1979-08-09	1989-05-17	Bracco Ind Chimica Spa	Derivati dell'acido 2,4,6-triiodo-isoftalico, metodo per la loro preparazione e mezzi di contrasto che li contengono.
US4396598A (en) *	1982-01-11	1983-08-02	Mallinckrodt, Inc.	Triiodoisophthalamide X-ray contrast agent
FR2541676A1 (fr) *	1983-02-25	1984-08-31	Guerbet Sa	Composes non-ioniques a structures benzenique iodee ou bromee et produits opacifiants en contenant
US5075502A (en) *	1989-12-13	1991-12-24	Mallinckrodt, Inc.	Nonionic x-ray contrast agents, compositions and methods
US5191120A (en) *	1989-12-13	1993-03-02	Mallinckrodt Medical, Inc.	Process for preparing nonionic X-ray contrast agents
IT1271107B (it) *	1994-11-29	1997-05-26	Zambon Spa	Processo per la preparazione di un intermedio utile nella sintesi di composti organici

1996
- 1996-05-17 US US08/650,094 patent/US5616795A/en not_active Expired - Lifetime
- 1996-05-17 SI SI9620012A patent/SI9620012A/sl unknown
- 1996-05-17 JP JP53534596A patent/JP4012566B2/ja not_active Expired - Lifetime
- 1996-05-17 CN CNB961905271A patent/CN1157367C/zh not_active Expired - Lifetime
- 1996-05-17 DE DE69601525T patent/DE69601525T2/de not_active Expired - Lifetime
- 1996-05-17 AT AT96916098T patent/ATE176663T1/de active
- 1996-05-17 EP EP96916098A patent/EP0773924B1/de not_active Expired - Lifetime
- 1996-05-17 CA CA002195636A patent/CA2195636C/en not_active Expired - Lifetime
- 1996-05-17 HU HU9700188A patent/HU216548B/hu unknown
- 1996-05-17 ES ES96916098T patent/ES2103252T3/es not_active Expired - Lifetime
- 1996-05-17 BR BR9606488A patent/BR9606488A/pt not_active Application Discontinuation
- 1996-05-17 DK DK96916098T patent/DK0773924T3/da active
- 1996-05-17 CZ CZ1997187A patent/CZ290345B6/cs not_active IP Right Cessation
- 1996-05-17 WO PCT/EP1996/002103 patent/WO1996037459A1/en active IP Right Grant
- 1996-05-17 AU AU58978/96A patent/AU702895B2/en not_active Expired
- 1996-05-17 DE DE0773924T patent/DE773924T1/de active Pending
- 1996-05-17 SK SK87-97A patent/SK8797A3/sk unknown
- 1996-05-17 PL PL96318311A patent/PL182447B1/pl unknown
- 1996-05-17 MX MX9700548A patent/MX9700548A/es unknown
- 1996-05-17 KR KR1019970700402A patent/KR100255914B1/ko not_active IP Right Cessation
- 1996-05-22 IL IL11835996A patent/IL118359A/xx not_active IP Right Cessation
1997
- 1997-01-21 NO NO19970261A patent/NO313696B1/no not_active IP Right Cessation
- 1997-09-30 GR GR970300027T patent/GR970300027T1/el unknown

Also Published As

Publication number	Publication date
ES2103252T1 (es)	1997-09-16
NO970261D0 (no)	1997-01-21
PL318311A1 (en)	1997-06-09
AU702895B2 (en)	1999-03-11
EP0773924B1 (de)	1999-02-10
KR100255914B1 (ko)	2000-05-01
NO970261L (no)	1997-05-02
BR9606488A (pt)	1997-11-25
CN1157367C (zh)	2004-07-14
CN1154689A (zh)	1997-07-16
CA2195636C (en)	2007-10-30
WO1996037459A1 (en)	1996-11-28
JPH10508874A (ja)	1998-09-02
PL182447B1 (pl)	2002-01-31
CA2195636A1 (en)	1996-11-28
AU5897896A (en)	1996-12-11
IL118359A (en)	2000-10-31
IL118359A0 (en)	1996-09-12
EP0773924A1 (de)	1997-05-21
ES2103252T3 (es)	1999-04-01
HUP9700188A3 (en)	1998-03-02
US5616795A (en)	1997-04-01
ATE176663T1 (de)	1999-02-15
CZ290345B6 (cs)	2002-07-17
MX9700548A (es)	1997-05-31
JP4012566B2 (ja)	2007-11-21
DE69601525T2 (de)	1999-06-24
HU216548B (hu)	1999-07-28
HUP9700188A1 (hu)	1998-01-28
SK8797A3 (en)	1997-08-06
CZ18797A3 (en)	1997-07-16
DE773924T1 (de)	1997-12-18
NO313696B1 (no)	2002-11-18
GR970300027T1 (en)	1997-09-30
SI9620012A (en)	1997-06-30
DK0773924T3 (da)	1999-09-20

Legal Events

Date	Code	Title	Description
2000-03-02	8364	No opposition during term of opposition
2002-02-07	8327	Change in the person/name/address of the patent owner	Owner name: BRACCO IMAGING S.P.A., MAILAND/MILANO, IT

Publication	Publication Date	Title
DE69601525D1 (de)	1999-03-25	Verfahren zur herstellung von dicarbonsäurechlorid
DE69521664D1 (de)	2001-08-16	Verfahren zur Herstellung von Trägerkatalysator für Olefinpolymerisation
DE69510563D1 (de)	1999-08-05	Verfahren zum caronylieren von aethylen und in diesem gebrauchtes katalytisches system
ATE254959T1 (de)	2003-12-15	Verfahren zur herstellung von carbonsäure-salze und katalysatoren verwendbar für solches verfahren
DE69105518D1 (de)	1995-01-12	Verfahren von hohem katalysatorgehalt zur herstellung von glucamide enthaltenden reinungsmitteln.
ATE192138T1 (de)	2000-05-15	Verfahren zur herstellung von halosubstituierter aromatischer säure
ATE189674T1 (de)	2000-02-15	Verfahren zur herstellung von dicarbonsäure- dichlorid
ATE262377T1 (de)	2004-04-15	Katalysatoren zur oxychlorierung von ethylen, verfahren zu ihrer herstellung, und oxychlorierungsverfahren
FI972261A (fi)	1997-05-28	Menetelmä 5-amino-2,4,6-trijodi-isoftaalihappodikloridin valmistamiseksi klooraamalla vastaavaa happoa tertiäärisen amiinisuolan tai kvaternäärisen ammoniumsuolan läsnäollessa
DE19681399T1 (de)	1998-05-20	Verfahren zur Herstellung von 5-Amino-2,4,6-triiodisophthalsäuredichlorid durch Chlorierung mit Thionylchlorid in Anwesenheit eines Katalysators
ATE237577T1 (de)	2003-05-15	Verfahren zur herstellung von substituierten aromatischen aminoverbindungen
ATE95207T1 (de)	1993-10-15	Verfahren zur herstellung eines thermoplastisch verarbeitbaren, aromatischen polyamids.
DE69405623D1 (de)	1997-10-23	Verfahren zur Herstellung von Cyclohexylaminen durch katalytische Hydrierung von Anilinen
DE69412934D1 (de)	1998-10-08	Verbessertes Verfahren zur Behandlung eines katalytischen Reformierungsproduktes
DE69802329D1 (de)	2001-12-13	Verfahren zur Herstellung von 3,4 disubstituirten Dinitroanilinen
DE59507763D1 (de)	2000-03-16	Verfahren zur Herstellung von Umsetzungsprodukten aus Poly(diorganosiloxanen)
DE59603777D1 (de)	2000-01-05	Verfahren zur Herstellung von 1-Brom-3,5-difluorbenzol
DE69906999D1 (de)	2003-05-22	Verfahren zur herstellung von s-n, n'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]- 5-[(2-hydroxy-1-oxopropyl)amino]-2, 4, 6-triiodo-1, 3-benzdicarboxamid
IT1274546B (it)	1997-07-17	Processo per la preparazione del dicloruro dell'acido 5-ammino-2,4,- 6-triiodoisoftalico
ATE276233T1 (de)	2004-10-15	Verfahren zur herstellung von polycarbamaten
DE59403537D1 (de)	1997-09-04	Verfahren zur Herstellung von 1-Brom-3,5-difluorbenzol
TH21704A (th)	1996-11-13	เพพไทด์ชนิดใหม่ที่มีผลปรับภูมิคุ้มกัน
DE69319234D1 (de)	1998-07-23	Verfahren zur Herstellung eines Katalysators für die Zubereitung von Methacrylsäure
TH21704B (th)	1996-11-13	เพพไทด์ชนิดใหม่ที่มีผลปรับภูมิคุ้มกัน
ATE164573T1 (de)	1998-04-15	Verfahren zur herstellung von 1-unsubstituierten 3-aminopyrrolen