US5756528A
(en)
*
|
1995-06-06 |
1998-05-26 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
US5972984A
(en)
*
|
1995-06-06 |
1999-10-26 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
JPH11509204A
(ja)
*
|
1995-07-13 |
1999-08-17 |
ユニバーシテイ・オブ・シンシナテイ |
神経線維腫症の治療に有用な化合物
|
US6008372A
(en)
*
|
1996-01-16 |
1999-12-28 |
Warner-Lambert Company |
Substituted dinaphthylmethyl and diheteroarylmethylacetyl histidine inhibitors of protein farnesyltransferase
|
AU703203B2
(en)
*
|
1996-01-30 |
1999-03-18 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
JP2000504017A
(ja)
*
|
1996-01-30 |
2000-04-04 |
メルク エンド カンパニー インコーポレーテッド |
ファルネシル―タンパク質転移酵素の阻害剤
|
US5968965A
(en)
*
|
1996-01-30 |
1999-10-19 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
US5981562A
(en)
*
|
1996-01-30 |
1999-11-09 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
WO1997027853A1
(en)
*
|
1996-01-30 |
1997-08-07 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
JP2000507586A
(ja)
*
|
1996-04-03 |
2000-06-20 |
メルク エンド カンパニー インコーポレーテッド |
ファルネシル―タンパク質転移酵素の阻害剤
|
US5922883A
(en)
*
|
1996-04-03 |
1999-07-13 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
US6300501B1
(en)
*
|
1996-05-22 |
2001-10-09 |
Warner-Lambert Company |
Histidine-(N-benzyl glycinamide) inhibitors of protein farnesyl transferase
|
EA199801031A1
(ru)
*
|
1996-05-22 |
1999-06-24 |
Варнер-Ламберт Компани |
Ингибиторы протеинфарнезилтрансферазы
|
US6093816A
(en)
|
1996-06-27 |
2000-07-25 |
Isis Pharmaceuticals, Inc. |
Cationic lipids
|
IL121203A
(en)
*
|
1996-07-01 |
2001-04-30 |
Lilly Co Eli |
1, 2, 3, 4-tetrahydroisoquinidines, process for their preparation and pharmaceutical compositions containing the same for treating hyperglycemia and hyperlipidemia
|
US6015817A
(en)
*
|
1996-12-05 |
2000-01-18 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
US5977134A
(en)
*
|
1996-12-05 |
1999-11-02 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
US5972966A
(en)
*
|
1996-12-05 |
1999-10-26 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
US5932590A
(en)
*
|
1996-12-05 |
1999-08-03 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
BR9713744A
(pt)
|
1996-12-17 |
2000-03-21 |
Warner Lambert Co |
Inibidores de cicloalquia da proteìna farnesil transferase
|
US6737410B1
(en)
|
1997-04-11 |
2004-05-18 |
Warner-Lambert Company |
Inhibitors of protein farnesyl transferase
|
WO1998046625A1
(en)
*
|
1997-04-11 |
1998-10-22 |
Warner-Lambert Company |
Dipeptide inhibitors of protein farnesyltransferase
|
US6060038A
(en)
*
|
1997-05-15 |
2000-05-09 |
Merck & Co., Inc. |
Radiolabeled farnesyl-protein transferase inhibitors
|
US6792084B1
(en)
*
|
1997-09-08 |
2004-09-14 |
Mci, Inc. |
Single telephone number access to multiple communications services
|
DE69914893T2
(de)
*
|
1998-04-27 |
2004-07-22 |
Warner-Lambert Co. Llc |
Glycinamidederivate mit funktionalisierter alkyl- und alkenylseitenkette als inhibitoren der farnesyltransferase
|
CA2331295A1
(en)
|
1998-05-12 |
1999-11-18 |
Warner-Lambert Company |
Combinations of protein farnesyltransferase and hmg coa reductase inhibitors and their use to treat cancer
|
US6458935B1
(en)
|
1999-06-23 |
2002-10-01 |
Merck & Co., Inc. |
Radiolabeled farnesyl-protein transferase inhibitors
|
US6624147B1
(en)
|
1999-09-28 |
2003-09-23 |
Rijksuniversiteit Leiden |
Inhibitors of prenylated pyrophosphate consuming enzymes
|
EP1090909A1
(de)
*
|
1999-09-28 |
2001-04-11 |
Rijksuniversiteit Leiden |
Hemmer für Enzyme, die Prenylpyrophosphate umsetzen
|
EP1496982A4
(de)
*
|
2002-04-16 |
2006-07-19 |
Merck & Co Inc |
Feste formen von salzen mit tyrosinkinase-wirkung
|
JP4866233B2
(ja)
*
|
2003-04-29 |
2012-02-01 |
ウニヴェルジテート・チューリッヒ |
fac配位により高効率で[M(OH2)3(CO)3]+標識化するために生体分子にカップリングさせるための、Nεおよび/またはNαで誘導体化され、金属および有機保護されたL−ヒスチジン
|
WO2005049589A2
(en)
*
|
2003-10-14 |
2005-06-02 |
Cadila Healthcare Limited |
Heterocyclic compounds for the treatment of hyperlipidemia, diabetes, obesity and similar diseases
|
ES2382814T3
(es)
|
2005-05-17 |
2012-06-13 |
Merck Sharp & Dohme Ltd. |
Ácido cis-4-[(4-clorofenil)sulfonil]-4-(2,5-difluorofenil)ciclohexanopropanoico para el tratamiento del cáncer
|
TW200804345A
(en)
|
2005-08-30 |
2008-01-16 |
Novartis Ag |
Substituted benzimidazoles and methods of preparation
|
GB0603041D0
(en)
|
2006-02-15 |
2006-03-29 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
TW200806284A
(en)
*
|
2006-03-31 |
2008-02-01 |
Alcon Mfg Ltd |
Prenyltransferase inhibitors for ocular hypertension control and the treatment of glaucoma
|
LT2010528T
(lt)
|
2006-04-19 |
2017-12-27 |
Novartis Ag |
6-o-pakeistieji benzoksazolo junginiai bei csf-1r signalo perdavimo slopinimo būdai
|
CA2664113C
(en)
|
2006-09-22 |
2013-05-28 |
Merck & Co., Inc. |
Use of platencin and platensimycin as fatty acid synthesis inhibitors to treat obesity, diabetes and cancer
|
US20110218176A1
(en)
|
2006-11-01 |
2011-09-08 |
Barbara Brooke Jennings-Spring |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
|
BRPI0806245B1
(pt)
|
2007-01-10 |
2022-01-25 |
Msd Italia S.R.L. |
Compostos de fórmula i e seus usos
|
BRPI0808523A2
(pt)
|
2007-03-01 |
2014-08-19 |
Novartis Vaccines & Diagnostic |
Inibidores de pim cinase e métodos de seu uso
|
CA2685967A1
(en)
|
2007-05-21 |
2008-11-21 |
Novartis Ag |
Csf-1r inhibitors, compositions, and methods of use
|
EP2170076B1
(de)
|
2007-06-27 |
2016-05-18 |
Merck Sharp & Dohme Corp. |
4-carboxybenzylamino-derivate als histondeacetylase-hemmer
|
US8691825B2
(en)
|
2009-04-01 |
2014-04-08 |
Merck Sharp & Dohme Corp. |
Inhibitors of AKT activity
|
WO2010144909A1
(en)
|
2009-06-12 |
2010-12-16 |
Novartis Ag |
Fused heterocyclic compounds and their uses
|
WO2011046771A1
(en)
|
2009-10-14 |
2011-04-21 |
Schering Corporation |
SUBSTITUTED PIPERIDINES THAT INCREASE p53 ACTIVITY AND THE USES THEREOF
|
CA2784807C
(en)
|
2009-12-29 |
2021-12-14 |
Dana-Farber Cancer Institute, Inc. |
Type ii raf kinase inhibitors
|
CN103080093A
(zh)
|
2010-03-16 |
2013-05-01 |
达纳-法伯癌症研究所公司 |
吲唑化合物及其应用
|
WO2011163330A1
(en)
|
2010-06-24 |
2011-12-29 |
Merck Sharp & Dohme Corp. |
Novel heterocyclic compounds as erk inhibitors
|
CA2805265A1
(en)
|
2010-08-02 |
2012-02-09 |
Merck Sharp & Dohme Corp. |
Rna interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (ctnnb1) gene expression using short interfering nucleic acid (sina)
|
WO2012024170A2
(en)
|
2010-08-17 |
2012-02-23 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS B VIRUS (HBV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA)
|
US8883801B2
(en)
|
2010-08-23 |
2014-11-11 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
|
US8946216B2
(en)
|
2010-09-01 |
2015-02-03 |
Merck Sharp & Dohme Corp. |
Indazole derivatives useful as ERK inhibitors
|
EP2615916B1
(de)
|
2010-09-16 |
2017-01-04 |
Merck Sharp & Dohme Corp. |
Kondensierte pyrazolderivate als neue erk-hemmer
|
WO2012058210A1
(en)
|
2010-10-29 |
2012-05-03 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA)
|
WO2012087772A1
(en)
|
2010-12-21 |
2012-06-28 |
Schering Corporation |
Indazole derivatives useful as erk inhibitors
|
JP2014514321A
(ja)
|
2011-04-21 |
2014-06-19 |
メルク・シャープ・アンド・ドーム・コーポレーション |
インスリン様増殖因子1受容体阻害剤
|
US9023865B2
(en)
|
2011-10-27 |
2015-05-05 |
Merck Sharp & Dohme Corp. |
Compounds that are ERK inhibitors
|
WO2013074986A1
(en)
|
2011-11-17 |
2013-05-23 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of c-jun-n-terminal kinase (jnk)
|
US20150299696A1
(en)
|
2012-05-02 |
2015-10-22 |
Sirna Therapeutics, Inc. |
SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
|
WO2014052563A2
(en)
|
2012-09-28 |
2014-04-03 |
Merck Sharp & Dohme Corp. |
Novel compounds that are erk inhibitors
|
US10112927B2
(en)
|
2012-10-18 |
2018-10-30 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 (CDK7)
|
WO2014063054A1
(en)
|
2012-10-19 |
2014-04-24 |
Dana-Farber Cancer Institute, Inc. |
Bone marrow on x chromosome kinase (bmx) inhibitors and uses thereof
|
WO2014063061A1
(en)
|
2012-10-19 |
2014-04-24 |
Dana-Farber Cancer Institute, Inc. |
Hydrophobically tagged small molecules as inducers of protein degradation
|
MX363243B
(es)
|
2012-11-28 |
2019-03-14 |
Merck Sharp & Dohme |
Composiciones para tratar cáncer y usos de dichas composiciones.
|
RU2690663C2
(ru)
|
2012-12-20 |
2019-06-05 |
Мерк Шарп И Доум Корп. |
Замещенные имидазопиридины в качестве ингибиторов hdm2
|
US9540377B2
(en)
|
2013-01-30 |
2017-01-10 |
Merck Sharp & Dohme Corp. |
2,6,7,8 substituted purines as HDM2 inhibitors
|
US20160194368A1
(en)
|
2013-09-03 |
2016-07-07 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
JP6491202B2
(ja)
|
2013-10-18 |
2019-03-27 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
サイクリン依存性キナーゼ7(cdk7)の多環阻害剤
|
ES2676734T3
(es)
|
2013-10-18 |
2018-07-24 |
Syros Pharmaceuticals, Inc. |
Compuestos heteroatómicos útiles para el tratamiento de enfermedades proliferativas
|
US9862688B2
(en)
|
2014-04-23 |
2018-01-09 |
Dana-Farber Cancer Institute, Inc. |
Hydrophobically tagged janus kinase inhibitors and uses thereof
|
US10017477B2
(en)
|
2014-04-23 |
2018-07-10 |
Dana-Farber Cancer Institute, Inc. |
Janus kinase inhibitors and uses thereof
|
JO3589B1
(ar)
|
2014-08-06 |
2020-07-05 |
Novartis Ag |
مثبطات كيناز البروتين c وطرق استخداماتها
|
WO2016105528A2
(en)
|
2014-12-23 |
2016-06-30 |
Dana-Farber Cancer Institute, Inc. |
Inhibitors of cyclin-dependent kinase 7 (cdk7)
|
CA2978518C
(en)
|
2015-03-27 |
2023-11-21 |
Nathanael S. Gray |
Inhibitors of cyclin-dependent kinases
|
EP3307728A4
(de)
|
2015-06-12 |
2019-07-17 |
Dana Farber Cancer Institute, Inc. |
Kombinationstherapie von transkriptionshemmern und kinasehemmern
|
EP4019515A1
(de)
|
2015-09-09 |
2022-06-29 |
Dana-Farber Cancer Institute, Inc. |
Hemmer von cyclinabhängigen kinasen
|
CA3032046A1
(en)
|
2016-09-16 |
2018-03-22 |
Research Triangle Institute |
Tetrahydroisoquinoline kappa opioid antagonists
|
JOP20190055A1
(ar)
|
2016-09-26 |
2019-03-24 |
Merck Sharp & Dohme |
أجسام مضادة ضد cd27
|
AU2018252546A1
(en)
|
2017-04-13 |
2019-10-10 |
Sairopa B.V. |
Anti-SIRPα antibodies
|
US10947234B2
(en)
|
2017-11-08 |
2021-03-16 |
Merck Sharp & Dohme Corp. |
PRMT5 inhibitors
|
WO2019148412A1
(en)
|
2018-02-01 |
2019-08-08 |
Merck Sharp & Dohme Corp. |
Anti-pd-1/lag3 bispecific antibodies
|
WO2020033284A1
(en)
|
2018-08-07 |
2020-02-13 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
EP3833668A4
(de)
|
2018-08-07 |
2022-05-11 |
Merck Sharp & Dohme Corp. |
Prmt5-inhibitoren
|