DE69520088D1 - Interferon-gamma-induzierendes Polypeptid monoklonal Antikörper, und Zusammensetzung für Interferon-gamma gebunden Krankheiten - Google Patents

Interferon-gamma-induzierendes Polypeptid monoklonal Antikörper, und Zusammensetzung für Interferon-gamma gebunden Krankheiten

Info

Publication number: DE69520088D1
Authority: DE; Germany
Prior art keywords: interferon; gamma; composition; monoclonal antibody; inducing polypeptide
Prior art date: 1994-11-15
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE69520088T

Other languages

English (en)

Other versions

DE69520088T2 (de

DE69520088T3 (de

Inventor

Shimpei Ushio

Kakuji Torigoe

Tadao Tanimoto

Haruki Okamura

Toshio Kunikata

Mutsuko Taniguchi

Keizo Kohno

Shigeharu Fukuda

Masashi Kurimoto

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Hayashibara Seibutsu Kagaku Kenkyujo KK

Original Assignee

Hayashibara Seibutsu Kagaku Kenkyujo KK

Hayashibara Biochemical Laboratories Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-15

Filing date

1995-11-10

Publication date

2001-03-22

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27523434&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69520088(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1995-02-23 Priority claimed from JP7058240A external-priority patent/JP2952750B2/ja

1995-09-18 Priority claimed from JP7262062A external-priority patent/JP2724987B2/ja

1995-11-10 Application filed by Hayashibara Seibutsu Kagaku Kenkyujo KK, Hayashibara Biochemical Laboratories Co Ltd filed Critical Hayashibara Seibutsu Kagaku Kenkyujo KK

2001-03-22 Publication of DE69520088D1 publication Critical patent/DE69520088D1/de

2004-07-29 Publication of DE69520088T2 publication Critical patent/DE69520088T2/de

2006-11-23 Application granted granted Critical

2006-11-23 Publication of DE69520088T3 publication Critical patent/DE69520088T3/de

2015-11-11 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

DE69520088T 1994-11-15 1995-11-10 Interferon-gamma-induzierendes Polypeptid monoklonal Antikörper, und Zusammensetzung für Interferon-gamma gebunden Krankheiten Expired - Lifetime DE69520088T3 (de)

Applications Claiming Priority (10)

Application Number	Priority Date	Filing Date	Title
JP30420394		1994-11-15
JP30420394		1994-11-15
JP7058240A JP2952750B2 (ja)	1995-02-23	1995-02-23	モノクローナル抗体
JP5824095		1995-02-23
JP7835795		1995-03-10
JP7835795		1995-03-10
JP7262062A JP2724987B2 (ja)	1994-11-15	1995-09-18	インターフェロン−γの産生を誘導するポリペプチド
JP26206295		1995-09-18
JP27498895		1995-09-29
JP27498895		1995-09-29

Publications (3)

Publication Number	Publication Date
DE69520088D1 true DE69520088D1 (de)	2001-03-22
DE69520088T2 DE69520088T2 (de)	2004-07-29
DE69520088T3 DE69520088T3 (de)	2006-11-23

Family

ID=27523434

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DE69535989T Expired - Lifetime DE69535989D1 (de)	1994-11-15	1995-11-10	Isoliertes Polypeptidfragment, das die Interferon-gamma Produktion induziert, und für das Polypeptid kodierende DNA
DE69520088T Expired - Lifetime DE69520088T3 (de)	1994-11-15	1995-11-10	Interferon-gamma-induzierendes Polypeptid monoklonal Antikörper, und Zusammensetzung für Interferon-gamma gebunden Krankheiten

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DE69535989T Expired - Lifetime DE69535989D1 (de)	1994-11-15	1995-11-10	Isoliertes Polypeptidfragment, das die Interferon-gamma Produktion induziert, und für das Polypeptid kodierende DNA

Country Status (7)

Country	Link
EP (2)	EP0712931B2 (de)
AU (1)	AU700948B2 (de)
CA (1)	CA2162353C (de)
DE (2)	DE69535989D1 (de)
DK (2)	DK0712931T4 (de)
ES (2)	ES2329099T3 (de)
TW (2)	TW581771B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP4004088B2 (ja)	1995-09-26	2007-11-07	株式会社林原生物化学研究所	免疫担当細胞においてインターフェロン−γの産生を誘導する蛋白質
US7135458B1 (en)	1995-11-15	2006-11-14	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Interferon-γ inducing polypeptide, pharmaceutical composition thereof, monoclonal antibody thereto, and methods of use
WO1997024441A1 (en) *	1995-12-29	1997-07-10	Incyte Pharmaceuticals, Inc.	Nucleic acids encoding interferon gamma inducing factor-2
AU3116697A (en) *	1996-05-20	1997-12-09	Schering Corporation	Human interleukin-1j and antagonists thereof
EP1669454A3 (de) *	1996-06-27	2009-04-01	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Genomische DNS, die für ein Polypeptid kodiert, welches die Fähigkeit besitzt, die Interferon-Gamma Herstellung zu induzieren
US6790442B1 (en)	1996-06-27	2004-09-14	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Genomic DNA encoding a polypeptide capable of inducing the production of interferon-γ
JPH1080270A (ja) *	1996-07-19	1998-03-31	Hayashibara Biochem Lab Inc	ポリペプチドをプロセッシングする酵素
TW515843B (en) *	1996-07-25	2003-01-01	Hayashibara Biochem Lab	Process for producing an active polypeptide inducing interferon-γ production
JP4024366B2 (ja) *	1996-11-29	2007-12-19	株式会社林原生物化学研究所	ポリペプチド
US7141393B2 (en)	1996-12-26	2006-11-28	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Interleukin-18-receptor proteins
JP3955352B2 (ja)	1997-02-25	2007-08-08	株式会社林原生物化学研究所	破骨細胞形成阻害剤
US6087116A (en) *	1997-03-12	2000-07-11	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Interleukin-18 (IL-18) receptor polypeptides and their uses
WO1999007851A1 (en) *	1997-08-07	1999-02-18	Toray Industries, Inc.	CANINE INTERLEUKIN 18, CANINE INTERLEUKIN 1β CONVERTASE, DNA SEQUENCES ENCODING THE SAME, PROCESS FOR PRODUCING INTERLE UKIN 18, AND REMEDIES FOR CANINE IMMUNOLOGICAL DISEASES
JP2001521906A (ja) *	1997-11-03	2001-11-13	ザ・ウイスター・インステイテユート・オブ・アナトミー・アンド・バイオロジー	血管新生を阻害し、癌を処置するための方法及び組成物
TWI227136B (en) *	1998-05-21	2005-02-01	Smithkline Beecham Corp	Novel pharmaceutical composition for the prevention and/or treatment of cancer
AR022952A1 (es)	1999-03-19	2002-09-04	Smithkline Beecham Corp	ANTICUERPO MONOCLONAL DE ROEDOR ESPECIFICAMENTE NEUTRALIZANTE PARA LA INTERLEUQUINA-18 HUMANA , UN FRAGMENTO FAB NEUTRALIZANTE o FRAGMENTO F(AB')2, UNA REGION DE COMPLEMENTARIEDAD DE CADENA LIGERA DE INMONOGLOBULINA(CDR), UNA MOLECULA DE ACIDO NUCLEICO, COMPOSICION FARMACEUTICA QUE LO COMPRENDE, EL
US6432678B1 (en) *	1999-06-21	2002-08-13	Smithkline Beecham Corporation	Macaca cynomolgus IL 18
NZ520392A (en)	2000-02-10	2005-04-29	Abbott Lab	Antibodies that bind human interleukin-18 and methods of making and using
GB0009503D0 (en) *	2000-04-17	2000-06-07	Univ Liverpool	Screening method for compounds
IL153201A0 (en) *	2000-06-02	2003-07-06	Smithkline Beecham Corp	Methods of treating viral diseases with il-18 and il-18 combinations
AU2001280442B2 (en)	2000-06-15	2005-10-27	Smithkline Beecham Corporation	Method for preparing a physiologically active il-18 polypeptide
CA2451955C (en)	2001-06-26	2015-09-29	Abgenix, Inc.	Antibodies to opgl
AU2002365269A1 (en) *	2001-10-26	2003-07-24	Centocor, Inc.	Mut-il-18 or mut-il-18r proteins, antibodies, compositions, methods and uses
JP2006517191A (ja)	2002-12-30	2006-07-20	アムジエン・インコーポレーテツド	共刺激因子を用いた併用療法
WO2004091517A2 (en)	2003-04-15	2004-10-28	Smithkline Beecham Corporation	Conjugates comprising human il-18 and substitution mutants thereof
US7968684B2 (en)	2003-11-12	2011-06-28	Abbott Laboratories	IL-18 binding proteins
US20050100965A1 (en)	2003-11-12	2005-05-12	Tariq Ghayur	IL-18 binding proteins
ATE526057T1 (de)	2004-08-20	2011-10-15	Glaxosmithkline Llc	Wundheilung durch verabreichung von menschlichem il-18
NZ572565A (en)	2006-05-25	2011-04-29	Glaxo Group Ltd	Modified humanised anti-interleukin-18 antibodies
AR065803A1 (es)	2007-03-23	2009-07-01	Smithkline Beecham Corp	Uso de un polipeptido de il- 18 humana y un anticuerpo anti- cd para preparar unmedicamento
US8168165B2 (en)	2008-12-23	2012-05-01	Abbott Laboratories	Alkylated interleukin-18 compositions
EP2534175A2 (de)	2010-02-09	2012-12-19	Glaxo Group Limited	Behandlung einer stoffwechselkrankheit
JOP20200308A1 (ar)	2012-09-07	2017-06-16	Novartis Ag	جزيئات إرتباط il-18
CN106687124B (zh)	2014-08-07	2022-03-15	冈村春树	并用il-18与分子靶向抗体的癌治疗药

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5457038A (en) *	1988-11-10	1995-10-10	Genetics Institute, Inc.	Natural killer stimulatory factor
JP3230531B2 (ja) *	1991-08-08	2001-11-19	光信佐藤	ＩＦＮ―γ誘導活性物質
EP0692536B1 (de) *	1994-07-14	2000-11-22	Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo	Protein, das Interferon-Gamma Herstellung induziert und monoklonaler Antikörper dagegen

1995
- 1995-10-04 TW TW090117498A patent/TW581771B/zh not_active IP Right Cessation
- 1995-10-04 TW TW084110504A patent/TW464656B/zh not_active IP Right Cessation
- 1995-11-07 CA CA2162353A patent/CA2162353C/en not_active Expired - Lifetime
- 1995-11-10 DE DE69535989T patent/DE69535989D1/de not_active Expired - Lifetime
- 1995-11-10 EP EP95308055A patent/EP0712931B2/de not_active Expired - Lifetime
- 1995-11-10 EP EP99104104A patent/EP0962531B1/de not_active Expired - Lifetime
- 1995-11-10 DK DK95308055T patent/DK0712931T4/da active
- 1995-11-10 DK DK99104104T patent/DK0962531T3/da active
- 1995-11-10 ES ES99104104T patent/ES2329099T3/es not_active Expired - Lifetime
- 1995-11-10 DE DE69520088T patent/DE69520088T3/de not_active Expired - Lifetime
- 1995-11-10 ES ES95308055T patent/ES2156199T5/es not_active Expired - Lifetime
- 1995-11-13 AU AU37796/95A patent/AU700948B2/en not_active Expired

Also Published As

Publication number	Publication date
EP0712931A2 (de)	1996-05-22
TW581771B (en)	2004-04-01
DK0962531T3 (da)	2009-10-05
DE69520088T2 (de)	2004-07-29
DK0712931T4 (da)	2006-08-21
DK0712931T3 (da)	2001-03-19
ES2156199T5 (es)	2006-12-16
CA2162353C (en)	2010-04-27
EP0712931B2 (de)	2006-04-19
EP0962531A3 (de)	1999-12-15
AU3779695A (en)	1996-05-23
EP0962531A2 (de)	1999-12-08
EP0962531B1 (de)	2009-08-05
ES2329099T3 (es)	2009-11-20
DE69520088T3 (de)	2006-11-23
EP0712931A3 (de)	1997-03-26
AU700948B2 (en)	1999-01-14
CA2162353A1 (en)	1996-05-16
ES2156199T3 (es)	2001-06-16
TW464656B (en)	2001-11-21
DE69535989D1 (de)	2009-09-17
EP0712931B1 (de)	2001-02-14

Legal Events

Date	Code	Title	Description
2002-02-07	8363	Opposition against the patent
2006-06-29	8366	Restricted maintained after opposition proceedings

Publication	Publication Date	Title
DE69520088D1 (de)	2001-03-22	Interferon-gamma-induzierendes Polypeptid monoklonal Antikörper, und Zusammensetzung für Interferon-gamma gebunden Krankheiten
NO980915L (no)	1998-05-06	Rekombinante anti-CD4-antistoff egnet for human terapi
PT719859E (pt)	2003-11-28	Anticorpo monoclonal anti-alfa v-integrina
EP0692536A3 (de)	1997-03-26	Protein, das Interferon-Gamma Herstellung induziert und monoklonaler Antikörper dagegen
ES552534A0 (es)	1987-05-16	Un metodo para obtener un polipeptido complementario de al menos una porcion de un peptido o proteina original.
DE59813875D1 (de)	2007-02-22	Ko-stimulierendes polypeptid von t-zellen, monoklonale antikörper sowie die herstellung und deren verwendung
DK1266965T3 (da)	2006-09-25	Rekombinante antistoffer til human terapi
DE69626859T2 (de)	2003-12-24	Il-13 rezeptor polypeptid
DE68917323D1 (de)	1994-09-15	Expressions-Vektor für Fusions-Proteine und Immunogen-Proteine.
EE9600192A (et)	1997-06-16	Antikehad, mis seostuvad putuka soole valkudele, ja nende kasutamine
EP0870826A4 (de)	2002-05-02	Neue proteine und gegen diese gerichtete monoklonale antikörper
LV11630A (lv)	1996-12-20	T sunu antigena receptora V apgabala pilna garuma olbaltumvielas
DE68925226D1 (de)	1996-02-08	Monoklonale Antikörper
DK1129186T3 (da)	2008-01-21	Et faktor VIII-polypeptid med faktor VIII:C-aktivitet
DE69531958D1 (de)	2003-11-20	(1-3)-beta-d-glukon-bindungsprotein, antikörper der dieses protein erkennt undverwendung des proteins und antikörper
ATA111789A (de)	1993-11-15	Humaner monoklonaler antikörper und hybridom zur herstellung desselben
DE69737651D1 (de)	2007-06-06	Cortistatin: neuropeptide, zusammensetzungen und methoden
TR199501542A2 (tr)	1996-07-21	Bagisiklik önleyici aktiviteye sahip monoklonal antikor parcalari.
DE69129582T2 (de)	1999-02-18	Antikörper gegen menschlichen plasmin-alpha 2-plasmininhibitor-komplex, hybridoma und immunoassay
DK270386A (da)	1986-12-11	Monoklonalt antistof til humant protein c, dets fremstilling og anvendelse
BR9709080A (pt)	1999-08-03	Anticorpo monoclonal anti-MP52 humano
FI954700A0 (fi)	1995-10-03	Monoklonaalinen vasta-aine 88BV59, jatkokloonit ja valmistusmenetelmä
BR1101125A (pt)	2003-01-14	Imunoglobulina humanizada e composição farmacêutica
ATE55414T1 (de)	1990-08-15	Polypeptid und polypeptidzusammensetzung.
ATE102291T1 (de)	1994-03-15	Auspuff-regelventil fuer zweitakt-motoren und dessen verwendung.