DE69513226T2 - Verwendung von Azolen als Virustötende Substanzen in Lösungen von biologisch aktiven Proteinen - Google Patents

Verwendung von Azolen als Virustötende Substanzen in Lösungen von biologisch aktiven Proteinen

Info

Publication number
DE69513226T2
DE69513226T2 DE69513226T DE69513226T DE69513226T2 DE 69513226 T2 DE69513226 T2 DE 69513226T2 DE 69513226 T DE69513226 T DE 69513226T DE 69513226 T DE69513226 T DE 69513226T DE 69513226 T2 DE69513226 T2 DE 69513226T2
Authority
DE
Germany
Prior art keywords
biologically active
azoles
virus
solutions
active proteins
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Revoked
Application number
DE69513226T
Other languages
English (en)
Other versions
DE69513226D1 (de
Inventor
Milton B Dobkin
Paul K Ng
George B Dove
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Original Assignee
Bayer AG
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22849553&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69513226(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer AG, Bayer Corp filed Critical Bayer AG
Publication of DE69513226D1 publication Critical patent/DE69513226D1/de
Application granted granted Critical
Publication of DE69513226T2 publication Critical patent/DE69513226T2/de
Anticipated expiration legal-status Critical
Revoked legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2720/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsRNA viruses
    • C12N2720/00011—Details
    • C12N2720/12011—Reoviridae
    • C12N2720/12061—Methods of inactivation or attenuation
    • C12N2720/12063—Methods of inactivation or attenuation by chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011—Details
    • C12N2760/20011—Rhabdoviridae
    • C12N2760/20211—Vesiculovirus, e.g. vesicular stomatitis Indiana virus
    • C12N2760/20261—Methods of inactivation or attenuation
    • C12N2760/20263—Methods of inactivation or attenuation by chemical treatment
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/32011—Picornaviridae
    • C12N2770/32611—Poliovirus
    • C12N2770/32661—Methods of inactivation or attenuation
    • C12N2770/32663—Methods of inactivation or attenuation by chemical treatment

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69513226T 1994-04-11 1995-03-29 Verwendung von Azolen als Virustötende Substanzen in Lösungen von biologisch aktiven Proteinen Revoked DE69513226T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/226,593 US5514781A (en) 1994-04-11 1994-04-11 Use of azoles as virucidal agents in solutions of biologically active proteins

Publications (2)

Publication Number Publication Date
DE69513226D1 DE69513226D1 (de) 1999-12-16
DE69513226T2 true DE69513226T2 (de) 2000-04-13

Family

ID=22849553

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69513226T Revoked DE69513226T2 (de) 1994-04-11 1995-03-29 Verwendung von Azolen als Virustötende Substanzen in Lösungen von biologisch aktiven Proteinen

Country Status (12)

Country Link
US (1) US5514781A (de)
EP (1) EP0686694B1 (de)
JP (1) JP3735137B2 (de)
CN (1) CN1129139A (de)
AT (1) ATE186567T1 (de)
AU (1) AU687153B2 (de)
CA (1) CA2144674C (de)
DE (1) DE69513226T2 (de)
DK (1) DK0686694T3 (de)
ES (1) ES2139769T3 (de)
GR (1) GR3032546T3 (de)
SI (1) SI0686694T1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1115411C (zh) * 1998-01-26 2003-07-23 邹方霖 一种新型的灭活病毒的方法
AUPP751298A0 (en) * 1998-12-04 1999-01-07 Csl Limited Inactivation of non-enveloped viruses
BR0008405B1 (pt) 1999-02-22 2014-04-22 Baxter Int Composição de fator viii formulada sem a adição de albumina, uso de uma composição de fator viii, e, método de liofilizar uma formulação farmacêutica aquosa
DE102004015007A1 (de) * 2004-03-26 2005-10-13 Bayer Healthcare Ag Substituierte Imidazole
US20100168018A1 (en) * 2008-11-07 2010-07-01 Baxter International Inc. Factor viii formulations

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56113713A (en) * 1980-02-14 1981-09-07 Chemo Sero Therapeut Res Inst Preparation of immunoglobulin with high content of monomer
DE3315808A1 (de) * 1983-04-30 1984-10-31 Bayer Ag, 5090 Leverkusen Antivirale mittel
US4861791A (en) * 1983-08-29 1989-08-29 Sterling Drug Inc. Dihydro-oxazolyl substituted-phenyl-aliphatic lower alkyl and their use as antiviral agents
US4675385A (en) * 1985-03-27 1987-06-23 Alpha Therapeutic Corporation Isolation of human plasma procoagulant protein factor VIII from biological factors
DE3511411A1 (de) * 1985-03-29 1986-10-02 Basf Ag, 6700 Ludwigshafen Verwendung von azolylmethyloxiranen zur bekaempfung von viralen erkrankungen
US4661493A (en) * 1985-03-29 1987-04-28 Pfizer Inc. Tioconazole and related compounds for control of Herpes simplex virus
CA1280753C (en) * 1985-07-02 1991-02-26 Philip Michael Carabateas Process for preparing heterocyclic substituted- phenoxyalkyl isoxazoles and-furans
JPS6419023A (en) * 1987-04-21 1989-01-23 Green Cross Corp Heat treatment of fibrinogen and fibrinogen preparation
CA1329760C (en) * 1987-10-29 1994-05-24 Ted C. K. Lee Plasma and recombinant protein formulations in high ionic strength media
US5110907A (en) * 1989-08-01 1992-05-05 Alpha Therapeutic Corporation Factor viii complex purification using heparin affinity chromatography
ZA908935B (en) * 1989-11-13 1991-08-28 Merrell Dow Pharma Prevention of glycoprotein enveloped virus infectivity by pyridinyloxazole-2-ones
US5110910A (en) * 1991-03-25 1992-05-05 Miles Inc. Virucidal euglobulin precipitation
TW235963B (de) * 1992-01-16 1994-12-11 Shionogi & Co
US5288853A (en) * 1992-04-30 1994-02-22 Alpha Therapeutic Corporation Factor viii purification process
CA2099630A1 (en) * 1992-07-02 1994-01-03 Guy Dominic Diana Heterocyclyl-phenoxyalkyl-piperidinylpyridazines as antiviral agents
DK0627924T3 (da) * 1992-10-02 2001-04-30 Genetics Inst Sammensætning, der omfatter koagulationsfaktor VIII formulering, fremgangsmåde til dens fremstilling og anvendelse af et overfladeaktivt middel som stabilisator

Also Published As

Publication number Publication date
SI0686694T1 (en) 2000-04-30
ES2139769T3 (es) 2000-02-16
CA2144674A1 (en) 1995-10-12
CN1129139A (zh) 1996-08-21
EP0686694B1 (de) 1999-11-10
CA2144674C (en) 2010-01-12
AU687153B2 (en) 1998-02-19
AU1477295A (en) 1995-10-19
DK0686694T3 (da) 2000-05-08
JPH08175908A (ja) 1996-07-09
JP3735137B2 (ja) 2006-01-18
DE69513226D1 (de) 1999-12-16
GR3032546T3 (en) 2000-05-31
ATE186567T1 (de) 1999-11-15
US5514781A (en) 1996-05-07
EP0686694A1 (de) 1995-12-13

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Legal Events

Date Code Title Description
8363 Opposition against the patent
8331 Complete revocation