DE69511423T2 - Stabile umkehr- und mehrfachfluorkohlenstoffemulsionen - Google Patents

Stabile umkehr- und mehrfachfluorkohlenstoffemulsionen

Info

Publication number
DE69511423T2
DE69511423T2 DE69511423T DE69511423T DE69511423T2 DE 69511423 T2 DE69511423 T2 DE 69511423T2 DE 69511423 T DE69511423 T DE 69511423T DE 69511423 T DE69511423 T DE 69511423T DE 69511423 T2 DE69511423 T2 DE 69511423T2
Authority
DE
Germany
Prior art keywords
emulsions
reverse
fluorocarbon
water
phase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69511423T
Other languages
English (en)
Other versions
DE69511423D1 (de
Inventor
Jean Riess
Marie-Pierre Krafft
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alliance Pharmaceutical Corp
Original Assignee
Alliance Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alliance Pharmaceutical Corp filed Critical Alliance Pharmaceutical Corp
Application granted granted Critical
Publication of DE69511423D1 publication Critical patent/DE69511423D1/de
Publication of DE69511423T2 publication Critical patent/DE69511423T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0026—Blood substitute; Oxygen transporting formulations; Plasma extender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/41—Emulsifying
    • B01F23/414—Emulsifying characterised by the internal structure of the emulsion
    • B01F23/4144—Multiple emulsions, in particular double emulsions, e.g. water in oil in water; Three-phase emulsions
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
    • C08L71/02—Polyalkylene oxides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Colloid Chemistry (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Fire-Extinguishing Compositions (AREA)
  • Glass Compositions (AREA)
  • Carbon And Carbon Compounds (AREA)
DE69511423T 1994-06-09 1995-06-07 Stabile umkehr- und mehrfachfluorkohlenstoffemulsionen Expired - Fee Related DE69511423T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9407068A FR2720943B1 (fr) 1994-06-09 1994-06-09 Emulsions inverses stables à forte concentration en composé(s) fluoré(s) et leur utilisation pour l'administration pulmonaire de médicaments et pour la fabrication d'émulsions multiples.
PCT/EP1995/002205 WO1995033447A1 (en) 1994-06-09 1995-06-07 Stable reverse and multiple fluorocarbon emulsions

Publications (2)

Publication Number Publication Date
DE69511423D1 DE69511423D1 (de) 1999-09-16
DE69511423T2 true DE69511423T2 (de) 2000-01-05

Family

ID=9464044

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69511423T Expired - Fee Related DE69511423T2 (de) 1994-06-09 1995-06-07 Stabile umkehr- und mehrfachfluorkohlenstoffemulsionen

Country Status (12)

Country Link
US (1) US5904933A (de)
EP (1) EP0788347B1 (de)
JP (1) JPH10500976A (de)
AT (1) ATE183079T1 (de)
AU (1) AU706236B2 (de)
CA (1) CA2191436A1 (de)
DE (1) DE69511423T2 (de)
DK (1) DK0788347T3 (de)
ES (1) ES2137524T3 (de)
FR (1) FR2720943B1 (de)
GR (1) GR3031523T3 (de)
WO (1) WO1995033447A1 (de)

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US20050221339A1 (en) * 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
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WO2008021123A1 (en) 2006-08-07 2008-02-21 President And Fellows Of Harvard College Fluorocarbon emulsion stabilizing surfactants
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US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
KR101656121B1 (ko) 2010-03-17 2016-09-08 노바리크 게엠베하 안압 증가를 치료하기 위한 약학 조성물
EP2622103B2 (de) 2010-09-30 2022-11-16 Bio-Rad Laboratories, Inc. Sandwichassays in tröpfchen
EP2444063A1 (de) 2010-10-20 2012-04-25 Novaliq GmbH Flüssige pharmazeutische Zusammensetzungen zur Abgabe von Wirkstoffen
EP2462921A1 (de) 2010-11-11 2012-06-13 Novaliq GmbH Flüssige pharmazeutische Zusammensetzungen zur Behandlung einer Erkrankung der Hinterseite des Auges
EP3859011A1 (de) 2011-02-11 2021-08-04 Bio-Rad Laboratories, Inc. Verfahren zur bildung gemischter tröpfchen
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EP3488847B1 (de) 2012-09-12 2023-11-08 Novaliq GmbH Semifluorierte alkanzusammensetzungen
CN106511322B (zh) 2012-09-12 2021-09-17 诺瓦利克有限责任公司 包含半氟化烷烃的混合物的组合物
FR2996545B1 (fr) 2012-10-08 2016-03-25 Ecole Polytech Procede microfluidique de traitement et d'analyse d'une solution contenant un materiel biologique, et circuit microfluidique correspondant.
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US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
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WO2015103367A1 (en) 2013-12-31 2015-07-09 Raindance Technologies, Inc. System and method for detection of rna species
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US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions
PL3355990T3 (pl) 2015-09-30 2019-11-29 Novaliq Gmbh Semifluorowane związki oraz ich kompozycje
JP6642935B2 (ja) 2015-09-30 2020-02-12 ノバリック ゲーエムベーハー 眼投与用の半フッ素化化合物
JP2019520357A (ja) 2016-06-23 2019-07-18 ノバリック ゲーエムベーハー 局所投与方法
US20180042846A1 (en) * 2016-07-28 2018-02-15 Honeywell International Inc. Propellants and emulsification compositions
AU2017329772B2 (en) 2016-09-22 2023-02-02 Novaliq Gmbh Pharmaceutical compositions for use in the therapy of blepharitis
ES2965677T3 (es) 2016-09-23 2024-04-16 Novaliq Gmbh Composiciones oftálmicas que comprenden ciclosporina
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Also Published As

Publication number Publication date
WO1995033447A1 (en) 1995-12-14
EP0788347A1 (de) 1997-08-13
AU2788795A (en) 1996-01-04
ES2137524T3 (es) 1999-12-16
AU706236B2 (en) 1999-06-10
EP0788347B1 (de) 1999-08-11
FR2720943A1 (fr) 1995-12-15
FR2720943B1 (fr) 1996-08-23
JPH10500976A (ja) 1998-01-27
ATE183079T1 (de) 1999-08-15
GR3031523T3 (en) 2000-01-31
US5904933A (en) 1999-05-18
DK0788347T3 (da) 2000-02-28
CA2191436A1 (en) 1995-12-14
DE69511423D1 (de) 1999-09-16

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee