DE69511257D1 - Oxydativ reinigung von taxol und cephalomannine enthaltende biomasseauszüge mit hilfe von ozon und girard reagens - Google Patents
Oxydativ reinigung von taxol und cephalomannine enthaltende biomasseauszüge mit hilfe von ozon und girard reagensInfo
- Publication number
- DE69511257D1 DE69511257D1 DE69511257T DE69511257T DE69511257D1 DE 69511257 D1 DE69511257 D1 DE 69511257D1 DE 69511257 T DE69511257 T DE 69511257T DE 69511257 T DE69511257 T DE 69511257T DE 69511257 D1 DE69511257 D1 DE 69511257D1
- Authority
- DE
- Germany
- Prior art keywords
- oxydative
- reagens
- cephalomannine
- girard
- taxol
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B63/00—Purification; Separation; Stabilisation; Use of additives
- C07B63/02—Purification; Separation; Stabilisation; Use of additives by treatment giving rise to a chemical modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Epoxy Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/224,758 US5364947A (en) | 1992-07-02 | 1994-04-08 | Process for separating cephalomannine from taxol using ozone and water-soluble hydrazines or hydrazides |
| PCT/US1995/003975 WO1995027707A1 (en) | 1994-04-08 | 1995-03-30 | Oxidative purification of biomass extracts containing taxol and cephalomannine using ozone and girard reagents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69511257D1 true DE69511257D1 (de) | 1999-09-09 |
| DE69511257T2 DE69511257T2 (de) | 2000-02-17 |
Family
ID=22842064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69511257T Expired - Fee Related DE69511257T2 (de) | 1994-04-08 | 1995-03-30 | Oxydativ reinigung von taxol und cephalomannine enthaltende biomasseauszüge mit hilfe von ozon und girard reagens |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US5364947A (de) |
| EP (1) | EP0755387B1 (de) |
| AU (1) | AU2234295A (de) |
| CA (1) | CA2187337A1 (de) |
| DE (1) | DE69511257T2 (de) |
| WO (1) | WO1995027707A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5475120A (en) * | 1990-11-02 | 1995-12-12 | University Of Florida | Method for the isolation and purification of taxol and its natural analogues |
| CN1091105C (zh) * | 1997-08-01 | 2002-09-18 | 中国科学院武汉植物研究所 | 一种分离纯化紫杉醇和紫杉烷的方法 |
| KR100474228B1 (ko) * | 1998-10-28 | 2005-12-13 | 주식회사 보락 | 파크리탁셀의분리방법 |
| US6485696B1 (en) * | 1998-10-30 | 2002-11-26 | The United States Of America As Represented By The Secretary Of The Interior | Recovery/removal of metallic elements from waste water using ozone |
| EP2289549A3 (de) | 1999-10-01 | 2011-06-15 | Immunogen, Inc. | Immunokonjugate für Krebsbehandlung |
| CN1331859C (zh) * | 2005-01-04 | 2007-08-15 | 四川华申科技开发有限公司 | 分离紫杉醇和三尖杉磷碱的方法 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2601675B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent |
| FR2601676B1 (fr) * | 1986-07-17 | 1988-09-23 | Rhone Poulenc Sante | Procede de preparation du taxol et du desacetyl-10 taxol |
| US4876399A (en) * | 1987-11-02 | 1989-10-24 | Research Corporation Technologies, Inc. | Taxols, their preparation and intermediates thereof |
| US4942184A (en) * | 1988-03-07 | 1990-07-17 | The United States Of America As Represented By The Department Of Health And Human Services | Water soluble, antineoplastic derivatives of taxol |
| FR2629818B1 (fr) * | 1988-04-06 | 1990-11-16 | Centre Nat Rech Scient | Procede de preparation du taxol |
| US4960790A (en) * | 1989-03-09 | 1990-10-02 | University Of Kansas | Derivatives of taxol, pharmaceutical compositions thereof and methods for the preparation thereof |
| US5019504A (en) * | 1989-03-23 | 1991-05-28 | The United States Of America As Represented By The Secretary Of Agriculture | Production of taxol or taxol-like compounds in cell culture |
| US5059699A (en) * | 1990-08-28 | 1991-10-22 | Virginia Tech Intellectual Properties, Inc. | Water soluble derivatives of taxol |
| US5334732A (en) * | 1992-07-02 | 1994-08-02 | Hauser Chemical Research, Inc. | Oxidation of cephalomannine with ozone in the presence of taxol |
-
1994
- 1994-04-08 US US08/224,758 patent/US5364947A/en not_active Expired - Lifetime
-
1995
- 1995-03-30 EP EP95915472A patent/EP0755387B1/de not_active Expired - Lifetime
- 1995-03-30 CA CA002187337A patent/CA2187337A1/en not_active Abandoned
- 1995-03-30 WO PCT/US1995/003975 patent/WO1995027707A1/en active IP Right Grant
- 1995-03-30 DE DE69511257T patent/DE69511257T2/de not_active Expired - Fee Related
- 1995-03-30 AU AU22342/95A patent/AU2234295A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69511257T2 (de) | 2000-02-17 |
| WO1995027707A1 (en) | 1995-10-19 |
| EP0755387A1 (de) | 1997-01-29 |
| AU2234295A (en) | 1995-10-30 |
| US5364947A (en) | 1994-11-15 |
| CA2187337A1 (en) | 1995-10-19 |
| EP0755387B1 (de) | 1999-08-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |