DE69507482T2 - Hochdispergierte magnetische metalloxidteilchen,produktionsverfahren und anwendung - Google Patents

Hochdispergierte magnetische metalloxidteilchen,produktionsverfahren und anwendung

Info

Publication number
DE69507482T2
DE69507482T2 DE69507482T DE69507482T DE69507482T2 DE 69507482 T2 DE69507482 T2 DE 69507482T2 DE 69507482 T DE69507482 T DE 69507482T DE 69507482 T DE69507482 T DE 69507482T DE 69507482 T2 DE69507482 T2 DE 69507482T2
Authority
DE
Germany
Prior art keywords
pct
application
metal oxide
production process
oxide particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69507482T
Other languages
English (en)
Other versions
DE69507482D1 (de
Inventor
Werner Sieber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Chiron Diagnostics Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Diagnostics Corp filed Critical Chiron Diagnostics Corp
Publication of DE69507482D1 publication Critical patent/DE69507482D1/de
Application granted granted Critical
Publication of DE69507482T2 publication Critical patent/DE69507482T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/01—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials
    • H01F1/03—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity
    • H01F1/12—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials
    • H01F1/14—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials metals or alloys
    • H01F1/147—Alloys characterised by their composition
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B03—SEPARATION OF SOLID MATERIALS USING LIQUIDS OR USING PNEUMATIC TABLES OR JIGS; MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C—MAGNETIC OR ELECTROSTATIC SEPARATION OF SOLID MATERIALS FROM SOLID MATERIALS OR FLUIDS; SEPARATION BY HIGH-VOLTAGE ELECTRIC FIELDS
    • B03C1/00—Magnetic separation
    • B03C1/005—Pretreatment specially adapted for magnetic separation
    • B03C1/01—Pretreatment specially adapted for magnetic separation by addition of magnetic adjuvants
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G01N33/5434—Magnetic particles using magnetic particle immunoreagent carriers which constitute new materials per se
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/0036—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties showing low dimensional magnetism, i.e. spin rearrangements due to a restriction of dimensions, e.g. showing giant magnetoresistivity
    • H01F1/0045—Zero dimensional, e.g. nanoparticles, soft nanoparticles for medical/biological use
    • H01F1/0054—Coated nanoparticles, e.g. nanoparticles coated with organic surfactant
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/01—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials
    • H01F1/03—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity
    • H01F1/12—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials
    • H01F1/34—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials non-metallic substances, e.g. ferrites
    • H01F1/36—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of inorganic materials characterised by their coercivity of soft-magnetic materials non-metallic substances, e.g. ferrites in the form of particles
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01F—MAGNETS; INDUCTANCES; TRANSFORMERS; SELECTION OF MATERIALS FOR THEIR MAGNETIC PROPERTIES
    • H01F1/00—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties
    • H01F1/44—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids
    • H01F1/445—Magnets or magnetic bodies characterised by the magnetic materials therefor; Selection of materials for their magnetic properties of magnetic liquids, e.g. ferrofluids the magnetic component being a compound, e.g. Fe3O4
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/20—Magnetic particle immunoreagent carriers the magnetic material being present in the particle core
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/30—Magnetic particle immunoreagent carriers the magnetic material being dispersed in the polymer composition before their conversion into particulate form
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/86—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids the coating being pre-functionalised for attaching immunoreagents, e.g. aminodextran
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2446/00—Magnetic particle immunoreagent carriers
    • G01N2446/80—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids
    • G01N2446/90—Magnetic particle immunoreagent carriers characterised by the agent used to coat the magnetic particles, e.g. lipids characterised by small molecule linker used to couple immunoreagents to magnetic particles
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00—Stock material or miscellaneous articles
    • Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2991—Coated
    • Y10T428/2993—Silicic or refractory material containing [e.g., tungsten oxide, glass, cement, etc.]
    • Y10T428/2995—Silane, siloxane or silicone coating
DE69507482T 1994-07-07 1995-06-22 Hochdispergierte magnetische metalloxidteilchen,produktionsverfahren und anwendung Expired - Fee Related DE69507482T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH217694 1994-07-07
PCT/EP1995/002441 WO1996002060A1 (en) 1994-07-07 1995-06-22 Highly disperse magnetic metal oxide particles, processes for their preparation and their use

Publications (2)

Publication Number Publication Date
DE69507482D1 DE69507482D1 (de) 1999-03-04
DE69507482T2 true DE69507482T2 (de) 1999-08-19

Family

ID=4227673

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69507482T Expired - Fee Related DE69507482T2 (de) 1994-07-07 1995-06-22 Hochdispergierte magnetische metalloxidteilchen,produktionsverfahren und anwendung

Country Status (10)

Country Link
US (1) US5776360A (de)
EP (1) EP0769195B1 (de)
JP (1) JPH10502494A (de)
KR (1) KR970705154A (de)
AT (1) ATE176077T1 (de)
BR (1) BR9508246A (de)
CA (1) CA2194554A1 (de)
DE (1) DE69507482T2 (de)
PL (1) PL318099A1 (de)
WO (1) WO1996002060A1 (de)

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DE19614136A1 (de) * 1996-04-10 1997-10-16 Inst Neue Mat Gemein Gmbh Verfahren zur Herstellung agglomeratfreier nanoskaliger Eisenoxidteilchen mit hydrolysebeständigem Überzug
US6689485B2 (en) * 1997-01-17 2004-02-10 The Penn State Research Foundation Powerful reductant for decontamination of groundwater and surface streams
US5989768A (en) * 1997-03-06 1999-11-23 Cabot Corporation Charge-modified metal oxides with cyclic silazane and electrostatographic systems incorporating same
US6074884A (en) * 1997-10-09 2000-06-13 Coulter International Corp. Stable protein-nickel particles and methods of production and use thereof
US6337215B1 (en) * 1997-12-01 2002-01-08 International Business Machines Corporation Magnetic particles having two antiparallel ferromagnetic layers and attached affinity recognition molecules
IL123468A (en) * 1998-02-26 2001-08-26 Yissum Res Dev Co Methods for the preparation of nanosized material particles
US6254634B1 (en) * 1998-06-10 2001-07-03 Surmodics, Inc. Coating compositions
JP2000348918A (ja) * 1999-06-02 2000-12-15 Seiko Epson Corp 希土類ボンド磁石、希土類ボンド磁石用組成物および希土類ボンド磁石の製造方法
FR2804102B1 (fr) * 2000-01-26 2002-08-16 Rhodia Terres Rares Dispersion colloidale aqueuse d'un compose de cerium et d'au moins un autre element choisi parmi les terres rares, des metaux de transition, l'aluminium, le gallium et le zirconium, procede de preparation et utilisation
US7169618B2 (en) * 2000-06-28 2007-01-30 Skold Technology Magnetic particles and methods of producing coated magnetic particles
US20030045098A1 (en) * 2001-08-31 2003-03-06 Applied Materials, Inc. Method and apparatus for processing a wafer
WO2003021642A2 (en) * 2001-08-31 2003-03-13 Applied Materials, Inc. Method and apparatus for processing a wafer
DE10153639A1 (de) * 2001-10-31 2003-05-22 Inst Neue Mat Gemein Gmbh Superparamagnetisches Eisenoxid enthaltende Kompositpartikel
JP4078247B2 (ja) * 2003-05-02 2008-04-23 キヤノン株式会社 磁性体−生体物質複合体型構造体、磁性体に対して結合能を有するアミノ酸配列を有するペプチド断片及びその遺伝子、ならびに磁性体−生体物質複合体型構造体の製造方法
FR2855315B1 (fr) * 2003-05-23 2005-08-19 Centre Nat Rech Scient Ferrofluides stables en milieu neutre et ferrofluides modifies obtenus par modification de la surface des particules de ces ferrofluides
US20050227075A1 (en) * 2004-04-13 2005-10-13 Eastman Kodak Company Derivatized nanoparticle comprising metal-ion sequestrant
US20060194910A1 (en) * 2004-05-19 2006-08-31 Nobuo Miyatake Stabilization of polymers with zinc oxide nanoparticles
US7482382B2 (en) * 2004-05-19 2009-01-27 The Texas A&M University System Process for preparing nano-sized metal oxide particles
US20070004840A1 (en) * 2004-05-19 2007-01-04 Texas A&M University Zinc oxide polymer nanocomposites and methods of producing zinc oxide polymer nanocomposites
JP2005340673A (ja) * 2004-05-28 2005-12-08 Asahi Techno Glass Corp 六方晶フェライト磁性粉末およびその製造方法
DE102005046263A1 (de) * 2005-09-27 2007-03-29 Basf Ag Verfahren zur Herstellung oberflächenmodifizierter nanopartikulärer Metalloxide, Metallhydroxide, und/oder Metalloxidhydroxide
JP4820988B2 (ja) * 2005-11-04 2011-11-24 国立大学法人 香川大学 磁性微粒子とその製造方法およびそれらを用いた磁石とその製造方法
DE102006002596A1 (de) * 2006-01-18 2007-07-19 Tesa Ag Verbundfolie
WO2009017525A2 (en) * 2007-04-27 2009-02-05 Regents Of The University Of California Superparamagnetic colloidal nanocrystal structures
WO2008136132A1 (en) * 2007-05-01 2008-11-13 Kazufumi Ogawa Magnetic fine particles and production method therefor, and magnet using the same and production method therefore
US9180206B2 (en) 2007-05-14 2015-11-10 Empire Technology Development Llc Pharmaceutical preparation and manufacturing method thereof
US8344054B2 (en) * 2007-07-24 2013-01-01 The Texas A & M University System Polymer nanocomposites including dispersed nanoparticles and inorganic nanoplatelets
DE102008003615A1 (de) 2008-01-09 2009-07-16 Magforce Nanotechnologies Ag Magnetische Transducer
US20090247652A1 (en) * 2008-03-27 2009-10-01 Headwaters Technology Innovation, Llc Metal colloids and methods for making the same
JP2010123984A (ja) * 2010-01-12 2010-06-03 Bando Chem Ind Ltd 磁性粒子及び磁性粒子分散液
PT2742515T (pt) 2011-08-10 2016-07-14 Magforce Ag Dispositivo médico que compreende nanopartículas magnéticas aglomeradas revestidas com alcoxissilano
KR101413958B1 (ko) * 2013-05-24 2014-07-04 고센바이오비드 주식회사 다 작용기를 가지는 자성나노입자 제조방법
US11828929B2 (en) 2014-03-24 2023-11-28 Adidas Ag Color changing materials arranged in slow particle coloration materials
US9507183B2 (en) 2014-03-24 2016-11-29 Adidas Ag Apparatus for manipulating color changing materials in articles of wear
US9482785B2 (en) 2014-03-24 2016-11-01 Adidas Ag Method of applying and using color changing materials in articles of wear
US10698197B2 (en) * 2014-03-24 2020-06-30 Adidas Ag Color changing materials arranged in slow particle coloration materials

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US4554088A (en) * 1983-05-12 1985-11-19 Advanced Magnetics Inc. Magnetic particles for use in separations
US5206159A (en) * 1984-11-01 1993-04-27 Miles Inc., As Legal Successor By Merger With Technicon Instruments Corp. Polymer particles containing colloidal iron oxide granules for use as a magnetically responsive reagent carrier
US4795698A (en) * 1985-10-04 1989-01-03 Immunicon Corporation Magnetic-polymer particles
US4827945A (en) * 1986-07-03 1989-05-09 Advanced Magnetics, Incorporated Biologically degradable superparamagnetic materials for use in clinical applications
JPH0670921B2 (ja) * 1988-06-03 1994-09-07 松下電器産業株式会社 磁性流体とその製造方法およびそれを用いた磁気シール装置
WO1990015666A1 (en) * 1989-06-16 1990-12-27 Omni Quest Corporation Coated magnetic particles for use in separations
JP2979414B2 (ja) * 1989-09-29 1999-11-15 富士レビオ株式会社 磁性粒子およびそれを用いた免疫測定法
EP0585868B1 (de) * 1992-08-31 2000-03-01 Fujirebio Inc. Magnetisches Teilchen und seine Verwendung in einem Immunotest

Also Published As

Publication number Publication date
ATE176077T1 (de) 1999-02-15
EP0769195B1 (de) 1999-01-20
CA2194554A1 (en) 1996-01-25
KR970705154A (ko) 1997-09-06
AU2924095A (en) 1996-02-09
WO1996002060A1 (en) 1996-01-25
EP0769195A1 (de) 1997-04-23
JPH10502494A (ja) 1998-03-03
DE69507482D1 (de) 1999-03-04
US5776360A (en) 1998-07-07
AU685300B2 (en) 1998-01-15
BR9508246A (pt) 1997-09-30
PL318099A1 (en) 1997-05-12

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee