DE69423899D1 - Pseudo-oder nicht peptidartige bradykinin rezeptor antagoniste - Google Patents
Pseudo-oder nicht peptidartige bradykinin rezeptor antagonisteInfo
- Publication number
- DE69423899D1 DE69423899D1 DE69423899T DE69423899T DE69423899D1 DE 69423899 D1 DE69423899 D1 DE 69423899D1 DE 69423899 T DE69423899 T DE 69423899T DE 69423899 T DE69423899 T DE 69423899T DE 69423899 D1 DE69423899 D1 DE 69423899D1
- Authority
- DE
- Germany
- Prior art keywords
- bradykinin
- peptidal
- pseudo
- bradykinin receptor
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/18—Kallidins; Bradykinins; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Biochemistry (AREA)
- Rheumatology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11934193A | 1993-09-09 | 1993-09-09 | |
US11855893A | 1993-09-09 | 1993-09-09 | |
US08/118,550 US5552383A (en) | 1992-10-08 | 1993-09-09 | Bradykinin antagonist pseudopeptide derivatives of aminoalkanoic acids and related olefins |
US08/118,981 US5444048A (en) | 1992-10-08 | 1993-09-09 | Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids |
US28190694A | 1994-07-28 | 1994-07-28 | |
US28190894A | 1994-07-28 | 1994-07-28 | |
US08/281,907 US5541286A (en) | 1992-10-08 | 1994-07-28 | Bradykinin antagonist pseudopeptide derivatives of olefinic aminoalkanoic acids |
US08/281,904 US5686565A (en) | 1992-10-08 | 1994-07-28 | Bradykinin antagonist pseudopeptide derivatives of aminoalkanoic acids and related olefins |
PCT/US1994/010128 WO1995007294A1 (en) | 1993-09-09 | 1994-09-09 | Pseudo- and non-peptide bradykinin receptor antagonists |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69423899D1 true DE69423899D1 (de) | 2000-05-11 |
DE69423899T2 DE69423899T2 (de) | 2000-11-09 |
Family
ID=27574846
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69423899T Expired - Lifetime DE69423899T2 (de) | 1993-09-09 | 1994-09-09 | Pseudo-oder nicht peptidartige bradykinin rezeptor antagoniste |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0716661B1 (de) |
JP (1) | JPH11500100A (de) |
AT (1) | ATE191486T1 (de) |
CA (1) | CA2171446C (de) |
DE (1) | DE69423899T2 (de) |
ES (1) | ES2148347T3 (de) |
WO (1) | WO1995007294A1 (de) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69533704D1 (de) * | 1994-03-09 | 2004-12-02 | Cortech Inc | Bradykinin-antagonist peptide mit n-substituierten glycinen |
FR2746647B1 (fr) * | 1996-03-27 | 1998-05-15 | Oreal | Composition apaisante comprenant un extrait d'iridacee |
PL186769B1 (pl) * | 1995-09-07 | 2004-02-27 | Oreal | Zastosowanie wyciągu z Iridaceae i kompozycja zawierająca taki wyciąg |
FR2739553B1 (fr) * | 1995-10-06 | 1998-01-02 | Oreal | Utilisation d'antagonistes de la bradykinine pour stimuler ou induire la pousse des cheveux et/ou stopper leur chute |
DE19612067A1 (de) * | 1996-03-27 | 1997-10-02 | Hoechst Ag | Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung von chronisch fibrogenetischen Lebererkrankungen und akuten Lebererkrankungen |
DE19642289A1 (de) | 1996-10-14 | 1998-04-16 | Hoechst Ag | Verwendung von Bradykinin-Antagonisten zur Herstellung von Arzneimitteln zur Behandlung und Prävention der Alzheimer'schen Krankheit |
FR2756566B1 (fr) | 1996-12-04 | 1999-01-08 | Fournier Ind & Sante | Peptides agonistes du recepteur b2 de la bradykinine, procede de preparation et utilisation en therapeutique |
US6919349B2 (en) | 2000-09-25 | 2005-07-19 | Toray Industries, Inc. | Spiro compounds and adhesion molecule inhibitors containing the same as the active ingredient |
MXPA05002622A (es) | 2002-09-09 | 2005-09-08 | Johnson & Johnson | Derivados de 1,3,8,-triazaespiro [4.5]decan-4-ona sustituidos con hidroxialquilo utiles para el tratamiento de desordenes mediados por el receptor opioide huerfano. |
KR101165863B1 (ko) | 2004-03-11 | 2012-07-13 | 액테리온 파마슈티칼 리미티드 | 인돌-1-일-아세트산 유도체 |
DK1725553T3 (da) | 2004-03-11 | 2008-08-18 | Actelion Pharmaceuticals Ltd | Tetrahydropyridoindolderivater |
KR101213912B1 (ko) | 2004-08-26 | 2012-12-18 | 액테리온 파마슈티칼 리미티드 | Crth2 길항제로서의2-설파닐-벤조이미다졸-1-일-아세틱 애시드 유도체 |
AU2007289065B2 (en) * | 2006-09-01 | 2013-03-14 | Senhwa Biosciences, Inc. | Serine-threonine protein kinase and PARP modulators |
MX2009005641A (es) | 2006-11-28 | 2009-06-05 | Janssen Pharmaceutica Nv | Sales de 3-(3-amino-2-(r)-hidroxi-propil)-1-(4-fluoro-fenil)-8-(8- metil-naftalen-1-ilmetil)-1,3,8-triaza-espiro[4,5]deca n-4-ona. |
CA2683598C (en) | 2007-04-09 | 2015-11-17 | Janssen Pharmaceutica Nv | 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the orl-i receptor for the treatment of anxiety and depression |
CN102083830B (zh) | 2008-03-24 | 2014-11-12 | 梅迪维新技术公司 | 吡啶并[3,4-b]吲哚和应用方法 |
CA2775129A1 (en) * | 2009-09-23 | 2011-03-31 | Medivation Technologies, Inc. | Pyrido[3,4-b]indoles and methods of use |
CA3183740A1 (en) | 2020-06-10 | 2021-12-16 | Aligos Therapeutics, Inc. | Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections |
KR20240035513A (ko) | 2021-07-09 | 2024-03-15 | 알리고스 테라퓨틱스 인코포레이티드 | 항바이러스 화합물 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU3428089A (en) * | 1988-03-25 | 1989-10-16 | The Administrators Of The Tulane Eductional Fund | Therapeutic peptides |
CA2106762C (en) * | 1991-04-19 | 2000-10-10 | Donald J. Kyle | Bradykinin antagonist peptides |
US5521158A (en) * | 1992-10-08 | 1996-05-28 | Scios Nova Inc. | Pseudopeptide bradykinin receptor antagonists |
-
1994
- 1994-09-09 ES ES94929158T patent/ES2148347T3/es not_active Expired - Lifetime
- 1994-09-09 CA CA002171446A patent/CA2171446C/en not_active Expired - Lifetime
- 1994-09-09 EP EP94929158A patent/EP0716661B1/de not_active Expired - Lifetime
- 1994-09-09 DE DE69423899T patent/DE69423899T2/de not_active Expired - Lifetime
- 1994-09-09 WO PCT/US1994/010128 patent/WO1995007294A1/en active IP Right Grant
- 1994-09-09 JP JP7508795A patent/JPH11500100A/ja active Pending
- 1994-09-09 AT AT94929158T patent/ATE191486T1/de active
Also Published As
Publication number | Publication date |
---|---|
JPH11500100A (ja) | 1999-01-06 |
EP0716661B1 (de) | 2000-04-05 |
CA2171446A1 (en) | 1995-03-16 |
DE69423899T2 (de) | 2000-11-09 |
ATE191486T1 (de) | 2000-04-15 |
CA2171446C (en) | 2004-11-23 |
EP0716661A1 (de) | 1996-06-19 |
WO1995007294A1 (en) | 1995-03-16 |
ES2148347T3 (es) | 2000-10-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8327 | Change in the person/name/address of the patent owner |
Owner name: SCIOS INC., SUNNYVALE, CALIF., US |
|
8364 | No opposition during term of opposition |