DE69414194T2 - Aminosäurederivate und ihre Verwendung als Enkephalinase-Inhibitoren - Google Patents
Aminosäurederivate und ihre Verwendung als Enkephalinase-InhibitorenInfo
- Publication number
- DE69414194T2 DE69414194T2 DE69414194T DE69414194T DE69414194T2 DE 69414194 T2 DE69414194 T2 DE 69414194T2 DE 69414194 T DE69414194 T DE 69414194T DE 69414194 T DE69414194 T DE 69414194T DE 69414194 T2 DE69414194 T2 DE 69414194T2
- Authority
- DE
- Germany
- Prior art keywords
- amino acid
- acid derivatives
- enkephalinase inhibitors
- enkephalinase
- image
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C327/00—Thiocarboxylic acids
- C07C327/20—Esters of monothiocarboxylic acids
- C07C327/32—Esters of monothiocarboxylic acids having sulfur atoms of esterified thiocarboxyl groups bound to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Pyrane Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9308765A FR2707638B1 (fr) | 1993-07-16 | 1993-07-16 | Nouveaux dérivés d'amino-acides, leurs procédés de préparation et leur application thérapeutique. |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69414194D1 DE69414194D1 (de) | 1998-12-03 |
DE69414194T2 true DE69414194T2 (de) | 1999-04-22 |
Family
ID=9449318
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69414194T Expired - Fee Related DE69414194T2 (de) | 1993-07-16 | 1994-07-13 | Aminosäurederivate und ihre Verwendung als Enkephalinase-Inhibitoren |
Country Status (8)
Country | Link |
---|---|
US (2) | US5612371A (de) |
EP (1) | EP0634396B1 (de) |
JP (1) | JP3584496B2 (de) |
AT (1) | ATE172721T1 (de) |
DE (1) | DE69414194T2 (de) |
DK (1) | DK0634396T3 (de) |
ES (1) | ES2124861T3 (de) |
FR (1) | FR2707638B1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5760241A (en) * | 1995-12-28 | 1998-06-02 | Zambon Group S.P.A. | Thiol derivatives with metallopeptidase inhibitory activity |
FR2772027B1 (fr) * | 1997-12-10 | 2000-02-04 | Fournier Ind & Sante | Procede de preparation asymetrique de derives de l'acide 2-mercaptomethyl-3-phenyl-propanoique, utilisation pour synthese de principes actifs chiraux |
US6056363A (en) * | 1997-12-29 | 2000-05-02 | Maddox; Lee W. | Reclining computer chair apparatus |
ES2196721T3 (es) | 1998-02-16 | 2003-12-16 | Ajinomoto Kk | Metodo para producir un derivado de acido fenilpropionico opticamente activo. |
US6303799B1 (en) * | 1998-11-10 | 2001-10-16 | Naxcor | Polynucleotide crosslinking agents |
US6562995B1 (en) | 2000-12-21 | 2003-05-13 | Beacon Laboratories, Inc. | Delta dicarbonyl compounds and methods for using the same |
KR101441840B1 (ko) | 2003-09-29 | 2014-11-04 | 가부시키가이샤 니콘 | 노광장치, 노광방법 및 디바이스 제조방법 |
US7022627B2 (en) | 2003-10-31 | 2006-04-04 | Asm International N.V. | Method for the heat treatment of substrates |
US6883250B1 (en) * | 2003-11-04 | 2005-04-26 | Asm America, Inc. | Non-contact cool-down station for wafers |
US6940047B2 (en) * | 2003-11-14 | 2005-09-06 | Asm International N.V. | Heat treatment apparatus with temperature control system |
KR100785270B1 (ko) | 2006-09-08 | 2007-12-12 | 주식회사 대우일렉트로닉스 | 순간 가열 방식 스팀 청소기의 스팀 제어 장치 |
US11618763B2 (en) | 2019-12-19 | 2023-04-04 | Massachusetts Institute Of Technology | Selective valorization of biomass sugars |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2480747A1 (fr) * | 1980-04-17 | 1981-10-23 | Roques Bernard | Derives d'acides amines et leur application therapeutique |
US4401677A (en) * | 1981-10-09 | 1983-08-30 | E. R. Squibb & Sons, Inc. | Enkephalinase inhibitors |
US4722810A (en) * | 1984-08-16 | 1988-02-02 | E. R. Squibb & Sons, Inc. | Enkephalinase inhibitors |
EP0136883B1 (de) * | 1983-10-03 | 1987-11-25 | E.R. Squibb & Sons, Inc. | Enkephalinase Inhibitoren |
FR2556721B1 (fr) * | 1983-12-14 | 1986-05-16 | Roussel Uclaf | Nouveaux derives de o-mercaptopropanamide d'o amino-acides, leur procede de preparation, leur application comme medicaments et les compositions les renfermant |
FR2652087B1 (fr) * | 1989-09-15 | 1993-10-15 | Bioprojet Ste Civile | Derives d'amino-acides, leur procede de preparation et leurs applications therapeutiques. |
-
1993
- 1993-07-16 FR FR9308765A patent/FR2707638B1/fr not_active Expired - Fee Related
-
1994
- 1994-07-13 ES ES94401632T patent/ES2124861T3/es not_active Expired - Lifetime
- 1994-07-13 EP EP94401632A patent/EP0634396B1/de not_active Expired - Lifetime
- 1994-07-13 AT AT94401632T patent/ATE172721T1/de not_active IP Right Cessation
- 1994-07-13 DE DE69414194T patent/DE69414194T2/de not_active Expired - Fee Related
- 1994-07-13 DK DK94401632T patent/DK0634396T3/da active
- 1994-07-18 US US08/276,665 patent/US5612371A/en not_active Expired - Fee Related
- 1994-07-18 JP JP18774894A patent/JP3584496B2/ja not_active Expired - Fee Related
-
1995
- 1995-06-05 US US08/463,049 patent/US5646313A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US5612371A (en) | 1997-03-18 |
EP0634396A1 (de) | 1995-01-18 |
JPH07188158A (ja) | 1995-07-25 |
JP3584496B2 (ja) | 2004-11-04 |
DK0634396T3 (da) | 1999-07-05 |
FR2707638B1 (fr) | 1995-08-18 |
ES2124861T3 (es) | 1999-02-16 |
EP0634396B1 (de) | 1998-10-28 |
DE69414194D1 (de) | 1998-12-03 |
US5646313A (en) | 1997-07-08 |
FR2707638A1 (fr) | 1995-01-20 |
ATE172721T1 (de) | 1998-11-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO924433D0 (no) | Isoksazol-4-karboksylsyreamider og hydroksyalkyliden-cyaneddiksyreamider, legemidler inneholdende disse forbindelsene og deres anvendelse | |
DK0624595T3 (da) | Nor-galdesyrederivater, fremgangsmåde til deres fremstilling og anvendelse af disse forbindelser som lægemidler | |
DK0562512T3 (da) | Sulfonamidocarbonylpyridin-2-carboxylsyreamider samt deres anvendelse som lægemidler | |
EP0350846A3 (en) | Condensed heterocyclic compounds and their use in therapy | |
DK0741694T3 (da) | Phenyleddikesyrederivater, fremgangsmåder og mellemprodukter til deres fremstilling og midler indeholdende disse | |
IS1564B (is) | Aðferð við framleiðslu á N1-súbstitúeruðum bensimidasólafleiðum til að nota við lækningar | |
DK0530087T3 (da) | Hidtil ukendte naphthylethylurinstof- og naphthylethylthiourinstofforbindelser, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem | |
DK0726899T3 (da) | Nye pyrazincarboxamidderivater, deres fremstilling og deres anvendelse i lægemidler | |
DK0404283T3 (da) | 11alfa-aryl-4-estrener, fremgangsmåde til fremstilling af disse samt deres anvendelse som lægemidler | |
DE69904483D1 (de) | Nitrat-salze als arzneimittel | |
DE3679920D1 (de) | Spiro-3-heteroazolidinverbindungen und ihre salze, ihre herstellung und diese enthaltende pharmazeutische mittel. | |
DK0603649T3 (da) | Substituerede 4-phenyl-pyridoner og 4-phenyl-2-alkoxypyridiner som HMG-CoA-reduktase-inhibitorer | |
ATE110071T1 (de) | Pyridazinon-derivate und diese enthaltende pharmazeutische zubereitungen. | |
ATE172721T1 (de) | Aminosäurederivate und ihre verwendung als enkephalinase-inhibitoren | |
DK0952974T3 (da) | Biphenylderivater substitueret med en aromatisk eller heteroaromatisk gruppe og farmaceutiske og kosmetiske præparater indeholdende disse derivater | |
DK0548794T3 (da) | Polyaspartamidderivater som adsorptionsmidler for galdesyrer, polyaspartamidderivater ladet med galdesyrer, fremgangsmåder | |
DE69419640D1 (de) | Pharmakologische Verwendung von 5-Aminophthaloylhydrazide; ihre Zusammensetzung und Anwendung | |
PT861250E (pt) | Derivados de amidina e de isotioureia como inibidores de oxido nitrico sintase | |
DK0617035T3 (da) | Hetero-tricyclisk-substituerede phenyl-cyclohexan-carboxylsyrederivater. | |
ES2123728T3 (es) | Derivados de pirrolo-pirazina de actividad 5-ht3. | |
DK0625520T3 (da) | Thiazolotriazol- og thiazolodiazolderivater med fungicid aktivitet | |
DE3778642D1 (de) | Therapeutikum zur behandlung von magengeschwueren. | |
ATE140922T1 (de) | 3- oder 4-glykosyloxybenzopyranderivat und dieses enthaltende antiallergisches mittel | |
NO305556B1 (no) | Tiokarbamoylforbindelser og anvendelse derav samt middel for beskyttelse av tekniske materialer | |
SU1783774A1 (ru) | Натриевая соль n-(3-хлорбутен-2-ил)антраниловой кислоты, проявляющая противовоспалительную и анальгетическую активность |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |