DE69327480T2 - Verfahren zur Herstellung 9-Beta,10-Alpha-5,7-Dien-Steroiden - Google Patents

Verfahren zur Herstellung 9-Beta,10-Alpha-5,7-Dien-Steroiden

Info

Publication number
DE69327480T2
DE69327480T2 DE69327480T DE69327480T DE69327480T2 DE 69327480 T2 DE69327480 T2 DE 69327480T2 DE 69327480 T DE69327480 T DE 69327480T DE 69327480 T DE69327480 T DE 69327480T DE 69327480 T2 DE69327480 T2 DE 69327480T2
Authority
DE
Germany
Prior art keywords
beta
alpha
making
diene steroids
diene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69327480T
Other languages
English (en)
Other versions
DE69327480D1 (de
Inventor
Berthus Bout
Ronald Voorhaar
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duphar International Research BV
Original Assignee
Duphar International Research BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar International Research BV filed Critical Duphar International Research BV
Application granted granted Critical
Publication of DE69327480D1 publication Critical patent/DE69327480D1/de
Publication of DE69327480T2 publication Critical patent/DE69327480T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
    • C07J15/005—Retrosteroids (9 beta 10 alfa)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE69327480T 1992-02-27 1993-02-16 Verfahren zur Herstellung 9-Beta,10-Alpha-5,7-Dien-Steroiden Expired - Lifetime DE69327480T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP92200564 1992-02-27

Publications (2)

Publication Number Publication Date
DE69327480D1 DE69327480D1 (de) 2000-02-10
DE69327480T2 true DE69327480T2 (de) 2002-11-21

Family

ID=8210449

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69327480T Expired - Lifetime DE69327480T2 (de) 1992-02-27 1993-02-16 Verfahren zur Herstellung 9-Beta,10-Alpha-5,7-Dien-Steroiden

Country Status (8)

Country Link
US (1) US5304291A (de)
EP (1) EP0558119B1 (de)
JP (1) JP3544682B2 (de)
AT (1) ATE188482T1 (de)
CA (1) CA2090264C (de)
DE (1) DE69327480T2 (de)
ES (1) ES2140433T3 (de)
IL (1) IL104844A (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1062998B1 (de) * 1993-10-06 2003-03-26 The Kansai Electric Power Co., Inc. Verfahren zur Abscheidung von Kohlendioxid aus Verbrennungsabgasen
JP3081760B2 (ja) * 1993-11-10 2000-08-28 矢崎総業株式会社 防水保護カバー
US5587556A (en) * 1993-12-20 1996-12-24 Yazaki Corporation Protective casing for end connecting part of wire
US5594210A (en) * 1994-09-28 1997-01-14 Yazaki Corporation Waterproof protective cover
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
EP1714656B8 (de) * 2004-02-06 2017-09-20 Chugai Seiyaku Kabushiki Kaisha Ed-71-präparat
US7094775B2 (en) * 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
US20060003950A1 (en) * 2004-06-30 2006-01-05 Bone Care International, Inc. Method of treating prostatic diseases using a combination of vitamin D analogues and other agents
US20070082876A1 (en) * 2005-09-30 2007-04-12 Solvay Pharmaceuticals Gmbh Novel C18 modified retrosteroids as progesterone receptor modulator compounds
US20070212751A1 (en) * 2006-01-18 2007-09-13 Solvay Pharmaceuticals Gmbh Microbial method for the 11beta hydroxylation of 9beta, 10alpha-steriods
CN102558272B (zh) * 2010-12-24 2014-04-23 中国科学院理化技术研究所 光化学异构化反应合成9-β，10-α-去氢***缩酮的方法
CN104327147B (zh) * 2014-06-04 2016-11-23 正源堂（天津滨海新区）生物科技有限公司 一种麦角甾醇类化合物及其制备方法与应用
CN110790807B (zh) * 2019-11-04 2021-08-06 广西师范大学 利用LED光源制备9β,10α-去氢***二乙二缩酮的方法
CN112194696B (zh) * 2020-10-26 2022-03-08 西安国康瑞金制药有限公司 一种制备9β,10α-5,7-双烯甾体化合物的方法
CN113666981A (zh) * 2021-08-27 2021-11-19 江西百思康瑞药业有限公司 一种地屈孕酮的合成方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL112521C (de) * 1960-05-30
NL160869C (nl) * 1972-11-03 Philips Nv Luminescerend scherm, alsmede ontladingslamp en katho- de straalbuis, voorzien van een dergelijk scherm.
DE3561396D1 (de) * 1984-02-15 1988-02-18 Duphar Int Res Method of preparing 9beta,10alpha-5,7-diene-steroids

Also Published As

Publication number Publication date
US5304291A (en) 1994-04-19
ES2140433T3 (es) 2000-03-01
JP3544682B2 (ja) 2004-07-21
IL104844A0 (en) 1993-06-10
JPH0641060A (ja) 1994-02-15
ATE188482T1 (de) 2000-01-15
CA2090264A1 (en) 1993-08-28
EP0558119A2 (de) 1993-09-01
EP0558119B1 (de) 2000-01-05
IL104844A (en) 1997-06-10
CA2090264C (en) 2004-05-04
DE69327480D1 (de) 2000-02-10
EP0558119A3 (en) 1995-08-16

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