DE69322242D1 - Turbidimetrisches Immunassay mit Messung der Geschwindigkeit der Trübungsveränderung nach dem Anfang der Immunpräzipitationsreaktion - Google Patents
Turbidimetrisches Immunassay mit Messung der Geschwindigkeit der Trübungsveränderung nach dem Anfang der ImmunpräzipitationsreaktionInfo
- Publication number
- DE69322242D1 DE69322242D1 DE69322242T DE69322242T DE69322242D1 DE 69322242 D1 DE69322242 D1 DE 69322242D1 DE 69322242 T DE69322242 T DE 69322242T DE 69322242 T DE69322242 T DE 69322242T DE 69322242 D1 DE69322242 D1 DE 69322242D1
- Authority
- DE
- Germany
- Prior art keywords
- analyte
- immunoprecipitation reaction
- measurement
- rate
- liquid medium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/557—Immunoassay; Biospecific binding assay; Materials therefor using kinetic measurement, i.e. time rate of progress of an antigen-antibody interaction
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/27—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration
- G01N21/272—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands using photo-electric detection ; circuits for computing concentration for following a reaction, e.g. for determining photometrically a reaction rate (photometric cinetic analysis)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Mathematical Physics (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/916,519 US5371021A (en) | 1992-07-17 | 1992-07-17 | Initial rate photometric method for immunoassay |
PCT/US1993/003724 WO1994002853A1 (en) | 1992-07-17 | 1993-04-21 | Initial rate photometric method for immunoassay |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69322242D1 true DE69322242D1 (de) | 1999-01-07 |
DE69322242T2 DE69322242T2 (de) | 1999-04-22 |
Family
ID=25437408
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69322242T Expired - Fee Related DE69322242T2 (de) | 1992-07-17 | 1993-04-21 | Turbidimetrisches Immunassay mit Messung der Geschwindigkeit der Trübungsveränderung nach dem Anfang der Immunpräzipitationsreaktion |
Country Status (9)
Country | Link |
---|---|
US (2) | US5371021A (de) |
EP (1) | EP0604606B1 (de) |
JP (1) | JPH06511088A (de) |
AT (1) | ATE173829T1 (de) |
AU (1) | AU669904B2 (de) |
CA (1) | CA2116687A1 (de) |
DE (1) | DE69322242T2 (de) |
ES (1) | ES2125982T3 (de) |
WO (1) | WO1994002853A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6284472B1 (en) | 1998-10-05 | 2001-09-04 | Dade Behring Inc. | Method for extending the range of an immunoassay |
US20060141470A1 (en) * | 2003-02-14 | 2006-06-29 | Kalayoglu Murat V | Chlamydia pneumoniae associated chronic intraocular disorders and treatment thereof |
ITMI20030971A1 (it) * | 2003-05-15 | 2004-11-16 | Solvay Solexis Spa | Preparazione di perfluoropolieteri aventi almeno un terminale -ch2oh oppure -ch(cf3)oh. |
EP1496362B1 (de) * | 2003-07-09 | 2006-12-13 | Matsushita Electric Industrial Co., Ltd. | Turbidimetrisches Immuntestverfahren und zugehörige Vorrichtung |
WO2005052583A1 (ja) * | 2003-11-28 | 2005-06-09 | Olympus Corporation | 分析対象物質の検出方法 |
GB2426050A (en) * | 2005-05-09 | 2006-11-15 | Orion Diagnostica Oy | Method of measuring binding rate using sonication |
US7993855B2 (en) * | 2006-03-24 | 2011-08-09 | Aokin Ag | Use of additives to lower the rate of a binding reaction |
WO2008031051A2 (en) * | 2006-09-08 | 2008-03-13 | United Therapeutics Corporation | Clinical diagnosis of hepatic fibrosis using a novel panel of human serum protein biomarkers |
WO2010133967A1 (en) * | 2009-05-14 | 2010-11-25 | University Of Oxford | Clinical diagnosis of hepatic fibrosis using a novel panel of low abundant human plasma protein biomarkers |
RU2650424C1 (ru) * | 2017-02-27 | 2018-04-13 | Акционерное Общество "Концерн "Океанприбор" | Концентратомер подвижных инфузорий в жидких средах |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4305665A (en) * | 1975-01-29 | 1981-12-15 | Baxter Travenol Laboratories, Inc. | Nephelometer and nephelometer method for assaying immunochemical complex |
US4268171A (en) * | 1977-07-18 | 1981-05-19 | Beckman Instruments, Inc. | Method determining concentration in rate nephelometric immunochemical analysis |
JPS54108693A (en) * | 1978-02-14 | 1979-08-25 | Mitsubishi Chem Ind | Method and device for optically measuring antigennantibody reaction |
JPS54109494A (en) * | 1978-02-16 | 1979-08-28 | Teikoku Hormone Mfg Co Ltd | Method of measuring antigennantibody reaction |
US4204837A (en) * | 1978-03-14 | 1980-05-27 | Beckman Instruments, Inc. | Method of rate immunonephelometric analysis |
US4205954A (en) * | 1978-05-26 | 1980-06-03 | Warner-Lambert Company | Kinetic latex agglutinometry |
JPS5544903A (en) * | 1978-09-26 | 1980-03-29 | Chugai Pharmaceut Co Ltd | Method of quantitatively analyzing low molecular substance in humor |
DE2901327B1 (de) * | 1979-01-15 | 1980-07-24 | Boehringer Mannheim Gmbh | Verfahren zur Bestimmung eines opsonierenden oberflaechenbindenden alpha?-Glykoproteins |
JPS57175957A (en) * | 1981-04-24 | 1982-10-29 | Chugai Pharmaceut Co Ltd | Measuring method and device for antigen- antibody reaction |
US4604365A (en) * | 1981-06-02 | 1986-08-05 | Electro-Nucleonics, Inc. | Immunoprecipitation assay |
US4766083A (en) * | 1982-04-04 | 1988-08-23 | Wako Pure Chemical Industries, Ltd. | Method for the photometric determination of biological agglutination |
DE3212658C3 (de) * | 1982-04-05 | 1993-08-19 | American Hospital Supply Corp | Verfahren zur antigen-bestimmung |
US4521521A (en) * | 1983-03-11 | 1985-06-04 | E. I. Du Pont De Nemours And Company | Particle reagent size distribution measurements for immunoassay |
US4554257A (en) * | 1983-04-29 | 1985-11-19 | Aladjem Frederick J | Assaying immunoreactive and like substances by measurement of aggregate classes |
JPH0736016B2 (ja) * | 1984-05-11 | 1995-04-19 | 和光純薬工業株式会社 | 免疫グロブリンの定量方法 |
US4647544A (en) * | 1984-06-25 | 1987-03-03 | Nicoli David F | Immunoassay using optical interference detection |
DE3615384A1 (de) * | 1985-05-08 | 1986-11-13 | Nissui Seiyaku K.K., Tokio/Tokyo | Verfahren zur bestimmung des rheumafaktors und denaturiertes, menschliches (gamma)-globulin fuer das verfahren |
JPH0660901B2 (ja) * | 1985-08-30 | 1994-08-10 | 東ソー株式会社 | 酵素免疫測定法 |
US4835110A (en) * | 1985-12-23 | 1989-05-30 | Beckman Instruments, Inc. | Method for enhancing analysis timing in kinetic nephelometry |
WO1987003966A1 (en) * | 1985-12-23 | 1987-07-02 | Beckman Instruments, Inc. | Automatic immunochemistry analyzing apparatus and method |
US5169757A (en) * | 1987-05-20 | 1992-12-08 | Carleton University | Antibodies or antigens bound to a macroporous hydrophobic synthetic polymer cloth for immunological techniques |
JPH02500133A (ja) * | 1987-07-21 | 1990-01-18 | クールター・エレクトロニクス・インコーポレーテッド | ハプテンについての改良濁り測定抑制検定法 |
ES2056936T3 (es) * | 1987-09-30 | 1994-10-16 | Beckman Instruments Inc | Conjugado bidentado y metodo de utilizacion del mismo. |
US5019999A (en) * | 1988-09-30 | 1991-05-28 | Technicon Instruments Corporation | Immunoanalysis method for discriminating between antigen excess and antibody excess conditions |
DE3900493A1 (de) * | 1989-01-10 | 1990-07-12 | Thomae Gmbh Dr K | Verfahren zur bestimmung der fibrinolytischen gesamtaktivitaet im plasma |
-
1992
- 1992-07-17 US US07/916,519 patent/US5371021A/en not_active Expired - Lifetime
-
1993
- 1993-04-21 ES ES93912327T patent/ES2125982T3/es not_active Expired - Lifetime
- 1993-04-21 WO PCT/US1993/003724 patent/WO1994002853A1/en active IP Right Grant
- 1993-04-21 AT AT93912327T patent/ATE173829T1/de not_active IP Right Cessation
- 1993-04-21 AU AU42913/93A patent/AU669904B2/en not_active Ceased
- 1993-04-21 DE DE69322242T patent/DE69322242T2/de not_active Expired - Fee Related
- 1993-04-21 EP EP93912327A patent/EP0604606B1/de not_active Expired - Lifetime
- 1993-04-21 CA CA002116687A patent/CA2116687A1/en not_active Abandoned
- 1993-04-21 JP JP6504425A patent/JPH06511088A/ja active Pending
-
1994
- 1994-09-06 US US08/301,236 patent/US5583055A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE173829T1 (de) | 1998-12-15 |
WO1994002853A1 (en) | 1994-02-03 |
US5583055A (en) | 1996-12-10 |
AU4291393A (en) | 1994-02-14 |
US5371021A (en) | 1994-12-06 |
DE69322242T2 (de) | 1999-04-22 |
ES2125982T3 (es) | 1999-03-16 |
AU669904B2 (en) | 1996-06-27 |
JPH06511088A (ja) | 1994-12-08 |
EP0604606B1 (de) | 1998-11-25 |
CA2116687A1 (en) | 1994-02-03 |
EP0604606A1 (de) | 1994-07-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |