DE69320705D1 - Aminoalkylcarbamatester von Eserolin verwendbar als Inhibitoren von Cholinesteraseaktivität und Verfahren zu deren Herstellung - Google Patents
Aminoalkylcarbamatester von Eserolin verwendbar als Inhibitoren von Cholinesteraseaktivität und Verfahren zu deren HerstellungInfo
- Publication number
- DE69320705D1 DE69320705D1 DE69320705T DE69320705T DE69320705D1 DE 69320705 D1 DE69320705 D1 DE 69320705D1 DE 69320705 T DE69320705 T DE 69320705T DE 69320705 T DE69320705 T DE 69320705T DE 69320705 D1 DE69320705 D1 DE 69320705D1
- Authority
- DE
- Germany
- Prior art keywords
- eseroline
- inhibitors
- useful
- making
- methods
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI921559A IT1254996B (it) | 1992-06-25 | 1992-06-25 | Esteri amminoalchilcarbammici dell'eserolina atti all'impiego come anticolinesterasici e relativo procedimento di preparazione |
Publications (1)
Publication Number | Publication Date |
---|---|
DE69320705D1 true DE69320705D1 (de) | 1998-10-08 |
Family
ID=11363576
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69320705T Expired - Lifetime DE69320705D1 (de) | 1992-06-25 | 1993-06-22 | Aminoalkylcarbamatester von Eserolin verwendbar als Inhibitoren von Cholinesteraseaktivität und Verfahren zu deren Herstellung |
Country Status (8)
Country | Link |
---|---|
US (2) | US5302593A (de) |
EP (1) | EP0575954B1 (de) |
JP (1) | JPH06206882A (de) |
KR (1) | KR940005627A (de) |
AT (1) | ATE170522T1 (de) |
CA (1) | CA2099648A1 (de) |
DE (1) | DE69320705D1 (de) |
IT (1) | IT1254996B (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6133444A (en) * | 1993-12-22 | 2000-10-17 | Perseptive Biosystems, Inc. | Synthons for the synthesis and deprotection of peptide nucleic acids under mild conditions |
IT1271679B (it) * | 1994-07-18 | 1997-06-04 | Mediolanum Farmaceutici Srl | Derivati del fenilcarbammato atti all'impiego come anticolinesterasici |
JP2001518054A (ja) * | 1995-06-07 | 2001-10-09 | パーセプティブ バイオシステムズ,インコーポレーテッド | Pna−dnaキメラと、このキメラ合成用のpnaシントン |
US5952506A (en) * | 1997-04-24 | 1999-09-14 | American Home Products Corporation | Process for the synthesis of 4- 6- (hexylcarbamoyloxy) hexylcarbamoyloxy!-piperidine-1-carboxylic acid 4-phenoxyphenyl ester |
US6218383B1 (en) | 1998-08-07 | 2001-04-17 | Targacept, Inc. | Pharmaceutical compositions for the prevention and treatment of central nervous system disorders |
AU2011215870B2 (en) | 2010-02-09 | 2016-01-28 | The Johns Hopkins University | Methods and compositions for improving cognitive function |
WO2014078568A1 (en) | 2012-11-14 | 2014-05-22 | The Johns Hopkins University | Methods and compositions for treating schizophrenia |
CN105142623A (zh) | 2013-03-15 | 2015-12-09 | 艾吉因生物股份有限公司 | 用于改善认知功能的方法和组合物 |
EP3827820A1 (de) | 2013-03-15 | 2021-06-02 | The Johns Hopkins University | Brivaracetam zur verbesserung der kognitiven funktion |
CN112843005B (zh) | 2015-05-22 | 2023-02-21 | 艾吉因生物股份有限公司 | 左乙拉西坦的延时释放药物组合物 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4791107A (en) * | 1986-07-16 | 1988-12-13 | Hoechst-Roussel Pharmaceuticals, Inc. | Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use |
EP0513703A3 (en) * | 1991-05-13 | 1993-01-13 | Magis Farmaceutici S.P.A. | Carbamate esters of eseroline having anticholinesterase activity, a process for their preparation and relative pharmaceutical compositions containing them as the active principle |
-
1992
- 1992-06-25 IT ITMI921559A patent/IT1254996B/it active IP Right Grant
-
1993
- 1993-06-22 AT AT93109932T patent/ATE170522T1/de not_active IP Right Cessation
- 1993-06-22 DE DE69320705T patent/DE69320705D1/de not_active Expired - Lifetime
- 1993-06-22 EP EP93109932A patent/EP0575954B1/de not_active Expired - Lifetime
- 1993-06-23 US US08/079,921 patent/US5302593A/en not_active Expired - Fee Related
- 1993-06-24 JP JP5175912A patent/JPH06206882A/ja active Pending
- 1993-06-24 KR KR1019930011626A patent/KR940005627A/ko not_active Application Discontinuation
- 1993-06-24 CA CA002099648A patent/CA2099648A1/en not_active Abandoned
-
1994
- 1994-01-04 US US08/177,325 patent/US5424451A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
ATE170522T1 (de) | 1998-09-15 |
ITMI921559A1 (it) | 1993-12-25 |
JPH06206882A (ja) | 1994-07-26 |
ITMI921559A0 (it) | 1992-06-25 |
CA2099648A1 (en) | 1993-12-26 |
EP0575954A1 (de) | 1993-12-29 |
IT1254996B (it) | 1995-10-11 |
US5302593A (en) | 1994-04-12 |
US5424451A (en) | 1995-06-13 |
EP0575954B1 (de) | 1998-09-02 |
KR940005627A (ko) | 1994-03-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |