DE69302580T2 - Vernetztes polyhydroxyl-material zur enzymatisch gesteuerten arzneistofffreisetzung - Google Patents

Vernetztes polyhydroxyl-material zur enzymatisch gesteuerten arzneistofffreisetzung

Info

Publication number
DE69302580T2
DE69302580T2 DE69302580T DE69302580T DE69302580T2 DE 69302580 T2 DE69302580 T2 DE 69302580T2 DE 69302580 T DE69302580 T DE 69302580T DE 69302580 T DE69302580 T DE 69302580T DE 69302580 T2 DE69302580 T2 DE 69302580T2
Authority
DE
Germany
Prior art keywords
amylase
alpha
cross
crosslinked
drug release
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69302580T
Other languages
English (en)
Other versions
DE69302580D1 (de
Inventor
Mircea A Mateescu
Yves Dumoulin
Louis Cartilier
Vincent Lenaerts
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labopharm Inc
Original Assignee
Labopharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Labopharm Inc filed Critical Labopharm Inc
Publication of DE69302580D1 publication Critical patent/DE69302580D1/de
Application granted granted Critical
Publication of DE69302580T2 publication Critical patent/DE69302580T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2068Compounds of unknown constitution, e.g. material from plants or animals

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Zoology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69302580T 1992-07-24 1993-07-22 Vernetztes polyhydroxyl-material zur enzymatisch gesteuerten arzneistofffreisetzung Expired - Lifetime DE69302580T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91976292A 1992-07-24 1992-07-24
PCT/CA1993/000298 WO1994002121A1 (en) 1992-07-24 1993-07-22 Cross-linked polyhydroxylic material for enzymatically controlled drug release

Publications (2)

Publication Number Publication Date
DE69302580D1 DE69302580D1 (de) 1996-06-13
DE69302580T2 true DE69302580T2 (de) 1996-09-26

Family

ID=25442612

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69302580T Expired - Lifetime DE69302580T2 (de) 1992-07-24 1993-07-22 Vernetztes polyhydroxyl-material zur enzymatisch gesteuerten arzneistofffreisetzung

Country Status (18)

Country Link
EP (1) EP0651634B1 (de)
JP (1) JP3647859B2 (de)
KR (1) KR100304997B1 (de)
AT (1) ATE137668T1 (de)
AU (1) AU668198B2 (de)
CA (1) CA2140032C (de)
CZ (1) CZ283395B6 (de)
DE (1) DE69302580T2 (de)
ES (1) ES2086949T3 (de)
FI (1) FI950301A (de)
GR (1) GR3020476T3 (de)
HU (1) HU221591B (de)
MX (1) MX9304459A (de)
NO (1) NO308024B1 (de)
NZ (1) NZ254048A (de)
PL (1) PL173249B1 (de)
RU (1) RU2136270C1 (de)
WO (1) WO1994002121A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2173818A1 (fr) * 1996-04-10 1997-10-11 Francois Chouinard Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose
DE19640062B4 (de) * 1996-09-28 2006-04-27 Lts Lohmann Therapie-Systeme Ag Orale Zubereitung, enthaltend in einer in wässrigem Medium quellbaren Matrix wenigstens einen pharmazeutischen Wirkstoff
US5879707A (en) * 1996-10-30 1999-03-09 Universite De Montreal Substituted amylose as a matrix for sustained drug release
US5807575A (en) * 1997-02-14 1998-09-15 Rougier Inc. Manufacture of cross-linked amylose useful as a excipient for control release of active compounds
US6077537A (en) * 1997-05-21 2000-06-20 Warner-Lambert Company Non-sedating acrivastine product
CA2217238C (en) * 1997-10-24 2005-09-20 Louis Cartilier Cross-linked cellulose as a tablet excipient
MXPA02005562A (es) 1999-12-06 2004-09-10 Penwest Pharmaceuticals Co Superdesintegrante farmaceutico.
US6607748B1 (en) 2000-06-29 2003-08-19 Vincent Lenaerts Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
US8487002B2 (en) 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
TWI319713B (en) 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
DK1940467T3 (da) 2005-09-09 2017-02-13 Paladin Labs Inc Lægemiddelsammensætning med langvarig frigivelse
WO2007055329A1 (ja) 2005-11-11 2007-05-18 Asahi Kasei Chemicals Corporation 徐放性固形製剤
BR112013000190A2 (pt) 2010-07-06 2017-11-07 Gruenenthal Gmbh formas de dosagem de retenção gástrica compreendendo um análogo de gaba e um opioide
AR082167A1 (es) 2010-07-14 2012-11-14 Gruenenthal Gmbh Formas de dosificacion gastrorretentivas

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3181998A (en) * 1960-08-12 1965-05-04 Joseph L Kanig Tablet disintegration
US3493652A (en) * 1962-09-14 1970-02-03 Charles W Hartman Controlled release medicament
SE420565B (sv) * 1974-06-06 1981-10-19 Pharmacia Ab Hjelpmedel for intravaskuler administraring for anvendning i samband med intravaskuler administrering av en losning eller en suspension av ett diagnostiseringsmedel
DE3721574A1 (de) * 1987-06-30 1989-01-12 Kettelhack Riker Pharma Gmbh Arzneimittel in form von pellets mit enzymatisch kontrollierter arzneistoff-freisetzung

Also Published As

Publication number Publication date
PL173249B1 (pl) 1998-02-27
KR100304997B1 (ko) 2002-04-24
AU4555993A (en) 1994-02-14
NO950251L (no) 1995-01-23
NZ254048A (en) 1995-09-26
HUT75673A (en) 1997-05-28
HU221591B (hu) 2002-11-28
FI950301A0 (fi) 1995-01-24
EP0651634A1 (de) 1995-05-10
CZ15295A3 (en) 1995-09-13
MX9304459A (es) 1994-04-29
HU9500197D0 (en) 1995-03-28
DE69302580D1 (de) 1996-06-13
JP3647859B2 (ja) 2005-05-18
AU668198B2 (en) 1996-04-26
CA2140032A1 (en) 1994-02-03
ES2086949T3 (es) 1996-07-01
CA2140032C (en) 1999-01-26
EP0651634B1 (de) 1996-05-08
GR3020476T3 (en) 1996-10-31
NO950251D0 (no) 1995-01-23
RU2136270C1 (ru) 1999-09-10
WO1994002121A1 (en) 1994-02-03
CZ283395B6 (cs) 1998-04-15
NO308024B1 (no) 2000-07-10
FI950301A (fi) 1995-01-24
PL307234A1 (en) 1995-05-15
JPH08502036A (ja) 1996-03-05
ATE137668T1 (de) 1996-05-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: WITTE, WELLER & PARTNER, 70178 STUTTGART