DE69229490D1 - Melatonin enthaltende Arzneimittel - Google Patents

Melatonin enthaltende Arzneimittel

Info

Publication number
DE69229490D1
DE69229490D1 DE69229490T DE69229490T DE69229490D1 DE 69229490 D1 DE69229490 D1 DE 69229490D1 DE 69229490 T DE69229490 T DE 69229490T DE 69229490 T DE69229490 T DE 69229490T DE 69229490 D1 DE69229490 D1 DE 69229490D1
Authority
DE
Germany
Prior art keywords
profile
melatonin
diluent
coating
combination
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69229490T
Other languages
English (en)
Other versions
DE69229490T2 (de
Inventor
Nava Zisapel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Neurim Pharmaceuticals 1991 Ltd
Original Assignee
Neurim Pharmaceuticals 1991 Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24802245&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69229490(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Neurim Pharmaceuticals 1991 Ltd filed Critical Neurim Pharmaceuticals 1991 Ltd
Application granted granted Critical
Publication of DE69229490D1 publication Critical patent/DE69229490D1/de
Publication of DE69229490T2 publication Critical patent/DE69229490T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE69229490T 1991-05-09 1992-04-23 Melatonin enthaltende Arzneimittel Expired - Lifetime DE69229490T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69771491A 1991-05-09 1991-05-09

Publications (2)

Publication Number Publication Date
DE69229490D1 true DE69229490D1 (de) 1999-08-05
DE69229490T2 DE69229490T2 (de) 2000-02-17

Family

ID=24802245

Family Applications (2)

Application Number Title Priority Date Filing Date
DE200712000073 Pending DE122007000073I1 (de) 1991-05-09 1992-04-23 Melatonin enthaltene Arzneimittel
DE69229490T Expired - Lifetime DE69229490T2 (de) 1991-05-09 1992-04-23 Melatonin enthaltende Arzneimittel

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE200712000073 Pending DE122007000073I1 (de) 1991-05-09 1992-04-23 Melatonin enthaltene Arzneimittel

Country Status (11)

Country Link
US (2) US5500225A (de)
EP (1) EP0518468B1 (de)
JP (1) JPH072694A (de)
AT (1) ATE181670T1 (de)
DE (2) DE122007000073I1 (de)
DK (1) DK0518468T3 (de)
ES (1) ES2134789T3 (de)
GR (1) GR3031257T3 (de)
HK (1) HK1011932A1 (de)
LU (1) LU91378I2 (de)
NL (1) NL300306I1 (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6638963B1 (en) 1990-12-04 2003-10-28 Oregon Health And Science University Methods for treating circadian rhythm disorders
US5707652A (en) * 1990-12-04 1998-01-13 State Of Oregon Methods of treating circadian rhythm phase disorders
ATE141051T1 (de) * 1992-04-07 1996-08-15 Neurim Pharma 1991 Verwendung von melatonin zur herstellung eines arzneimittels zur behandlung der gutartigen prostatahyperplasie
IT1254995B (it) * 1992-06-24 1995-10-11 Farmaco contenente melatonina e/o agonisti, con somministrazione particolarmente efficace nelle patologie che interferiscono con i ritmi circandiani
US5385736A (en) * 1993-07-12 1995-01-31 Minnesota Mining And Manufacturing Company Transdermal melatonin delivery system
WO1995003043A1 (en) * 1993-07-26 1995-02-02 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education On Behalf Of The Oregon Health Sciences University Sustained release oral compositions containing melatonin
FR2718020B1 (fr) * 1994-04-01 1996-05-31 Biotec Centre Sa Composition galénique mucoadhésive hétérofonctionnelle.
DE4443175A1 (de) * 1994-12-05 1996-06-13 Jenapharm Gmbh Neue pulsatile Arzneiform
CZ291349B6 (cs) * 1995-02-01 2003-02-12 Neurim Pharmaceuticals Ltd. Léčivo pro prevenci nebo léčbu závislosti na benzodiazepinech
US6469044B1 (en) * 1995-02-01 2002-10-22 Neurim Pharmaceuticals (1991) Ltd. Method for treating patients suffering from drug dependencies which lead to plasma melationin deficiencies
US5688520A (en) * 1995-03-29 1997-11-18 Minnesota Mining And Manufacturing Company Transmucosal delivery of melatonin for prevention of migraine
CA2219978C (en) * 1995-06-07 2011-02-01 Ergo Science Incorporated Method for inhibiting neoplastic disease in mammals
US5792748A (en) * 1995-06-07 1998-08-11 The General Hospital Corporation Method for inhibiting neoplastic disease in mammals
DE19713141A1 (de) * 1996-03-29 1997-10-30 Labtec Gmbh Transdermales System mit Melatonin
DE19631084A1 (de) 1996-08-01 1998-02-05 Basf Ag Verwendung von (Meth)acrylsäure-Copolymeren zur Erhöhung der Permeabilität der Schleimhaut
PT951842E (pt) * 1999-01-20 2003-04-30 Nutricia Nv Formula de alimento adaptada para bebe
SK287508B6 (sk) 2000-01-05 2010-12-07 Neurim Pharmaceuticals (1991) Ltd. Použitie a formulácia prípravku na liečbu rezistencie voči antihypertenzívam a podobných stavov
US20020119191A1 (en) * 2000-04-24 2002-08-29 Hitoo Nishino Pharmaceutical or food composition for treatment or prevention of brain edema
IL144900A (en) 2001-08-14 2013-12-31 Neurim Pharma 1991 Melatonin and drugs containing it for use in the treatment of primary insomnia, and the manufacture of those drugs
US7365238B2 (en) * 2002-02-19 2008-04-29 The Procter And Gamble Company Absorbent article having a dehydration indicator
KR100501827B1 (ko) * 2002-09-24 2005-07-20 한국화학연구원 다층 코팅법을 이용한 멜라토닌 함유 타게팅 약물 전달 기구
US6703412B1 (en) * 2002-09-27 2004-03-09 Holly A. Rosenthal Method of treating sleeplessness with melatonin on an acute basis
TWI324604B (en) 2003-06-18 2010-05-11 Novartis Ag New use of staurosporine derivatives
US7799817B2 (en) * 2004-02-20 2010-09-21 Lifescape Biosciences Inc Compositions and methods for sleep regulation
EP2124907B1 (de) 2007-03-19 2018-05-30 Vita Sciences, Llc Transdermales pflaster und verfahren zur verabreichung von vitamin b12
WO2012103411A2 (en) 2011-01-28 2012-08-02 Zx Pharma, Llc Controlled-release melatonin composition and related methods
US9532952B2 (en) 2011-01-28 2017-01-03 Physician's Seal, LLC Controlled-release compositions of melatonin combined with sedative and/or analgesic ingredients
AU2012214553B2 (en) 2011-02-11 2015-07-09 Sociétés des Produits Nestlé S.A. Multiparticulate L-menthol formulations and related methods
US8808736B2 (en) 2011-02-11 2014-08-19 Zx Pharma, Llc Enteric coated multiparticulate controlled release peppermint oil composition and related methods
US8911780B2 (en) 2011-02-11 2014-12-16 Zx Pharma, Llc Multiparticulate L-menthol formulations and related methods
US9572528B1 (en) 2012-08-06 2017-02-21 Los Angeles Biomedical Research Insitute at Harbor-UCLA Medical Center Monitor for SIDS research and prevention
FR3000896B1 (fr) 2013-01-14 2016-08-26 Philippe Perovitch Forme galenique pour l'administration de principe(s) actif(s) permettant l'induction acceleree du sommeil et/ou le traitement des troubles du sommeil
PL2988824T3 (pl) 2013-04-23 2019-04-30 Zx Pharma Llc Wielocząsteczkowa kompozycja z otoczką dojelitową z białkową otoczką pośrednią
WO2016058985A1 (en) * 2014-10-13 2016-04-21 Therapicon S.R.L. Anydrous liquid melatonin composition
CN104546777A (zh) * 2014-12-16 2015-04-29 深圳翰宇药业股份有限公司 美乐托宁缓释组合物的制备方法、美乐托宁缓释片的制备方法
NL2015272B1 (en) * 2015-08-05 2017-05-02 Versailles B V Melatonin formulations and methods for preparation and use.
US10849856B2 (en) 2016-10-31 2020-12-01 Neurim Pharmaceuticals Ltd. Melatonin mini-tablets and method of manufacturing the same
SI3337462T1 (sl) * 2016-10-31 2021-01-29 Neurim Pharmaceuticals Ltd. Melantonin mini-tablete in metoda za izdelavo le-teh
WO2019038586A1 (en) 2017-08-19 2019-02-28 Ftf Pharma Private Limited PHARMACEUTICAL COMPOSITION OF MELATONIN
CN113072479A (zh) * 2021-03-26 2021-07-06 罗田县新普生药业有限公司 一种从褪黑素结晶母液中提取褪黑素的方法
WO2023134856A1 (de) * 2022-01-13 2023-07-20 Paditz Ekkehart Säuglingsnahrung und verfahren zu deren herstellung

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5584503A (en) * 1978-12-19 1980-06-25 Teijin Ltd Preparing cellulose ester based selective permeable membrane
CA1151862A (en) * 1980-01-24 1983-08-16 Thomas J. Fogarty Flexible calibrator
US4855325A (en) * 1985-01-16 1989-08-08 Naftchi Nosrat E Treatment of mammals suffering from damage to the central nervous system
DE3466215D1 (en) * 1983-05-18 1987-10-22 Univ Monash The use of melatonin for the manufacture of a medicament
US4600723A (en) * 1983-05-18 1986-07-15 Monash University Method for minimizing disturbances in circadian rhythms of bodily performance and function
AU571922B2 (en) * 1984-01-26 1988-04-28 Schering Agrochemicals Limited Veterinary implants comprising melatonin and derivatives thereof
US4654361A (en) * 1986-01-27 1987-03-31 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University Method of lowering intraocular pressure using melatonin
AU601736B2 (en) * 1986-05-23 1990-09-20 Sanofi Sante Nutrition Animale Sa Coated veterinary implants
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
EP0330652A1 (de) * 1987-02-13 1989-09-06 GRAZIOSI, Maurizio System um schuhunterteile atoxisch zu machen
US4855305A (en) * 1987-03-23 1989-08-08 Applied Medical Research Compositions and methods of effecting contraception utilizing melatonin
GB8727099D0 (en) * 1987-11-19 1987-12-23 Cellena Cell Eng A G Compositions containing melantonin/homologues
FR2630005B1 (fr) * 1988-04-14 1991-11-29 Goupil Jean Jacques Nouveau medicament anti-depresseur contenant du 5-methoxypsoralene
US4945103A (en) * 1989-01-17 1990-07-31 Michael Cohen Method of treating pre-menstrual syndrome
US5151446A (en) * 1989-09-25 1992-09-29 Northwestern University Substituted 2-amidotetralins as melatonin agonists and antagonists
JPH03145419A (ja) * 1989-10-31 1991-06-20 Shiseido Co Ltd 紫外線老化の防御薬剤

Also Published As

Publication number Publication date
HK1011932A1 (en) 1999-07-23
NL300306I1 (nl) 2008-01-02
US5498423A (en) 1996-03-12
EP0518468A1 (de) 1992-12-16
ES2134789T3 (es) 1999-10-16
EP0518468B1 (de) 1999-06-30
LU91378I2 (en) 2008-01-23
DE122007000073I1 (de) 2008-01-31
ATE181670T1 (de) 1999-07-15
DK0518468T3 (da) 2000-01-31
GR3031257T3 (en) 1999-12-31
US5500225A (en) 1996-03-19
DE69229490T2 (de) 2000-02-17
JPH072694A (ja) 1995-01-06

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