US5208233A
(en)
*
|
1989-09-15 |
1993-05-04 |
The United States Of America As Represented By The Department Of Health And Human Services |
Anti-hypertensive compositions of secondary amine-nitric oxide adducts and use thereof
|
US5721365A
(en)
*
|
1989-09-15 |
1998-02-24 |
Us Health |
N-substituted piperazine NONOates
|
US5814666A
(en)
*
|
1992-04-13 |
1998-09-29 |
The United States As Represented By The Department Of Health And Human Services |
Encapsulated and non-encapsulated nitric oxide generators used as antimicrobial agents
|
US5691423A
(en)
*
|
1992-08-24 |
1997-11-25 |
The United States Of America As Represented By The Department Of Health And Human Services |
Polysaccharide-bound nitric oxide-nucleophile adducts
|
US6200558B1
(en)
|
1993-09-14 |
2001-03-13 |
The United States Of America As Represented By The Department Of Health And Human Services |
Biopolymer-bound nitric oxide-releasing compositions, pharmaceutical compositions incorporating same and methods of treating biological disorders using same
|
US5910316A
(en)
|
1992-08-24 |
1999-06-08 |
The United States Of America, As Represented By The Department Of Health And Human Services |
Use of nitric oxide-releasing agents to treat impotency
|
US6255277B1
(en)
|
1993-09-17 |
2001-07-03 |
Brigham And Women's Hospital |
Localized use of nitric oxide-adducts to prevent internal tissue damage
|
US5811463A
(en)
*
|
1993-10-06 |
1998-09-22 |
University Of British Columbia |
Compositions and method for relaxing smooth muscles
|
AU7972294A
(en)
*
|
1993-10-07 |
1995-05-01 |
Entremed, Inc |
Encapsulated and non-encapsulated nitric oxide generators used as antimicrobial agents
|
US5840759A
(en)
*
|
1993-10-08 |
1998-11-24 |
The United States Of America As Represented By The Department Of Health And Human Services |
Use of nitric oxide releasing compounds to protect noncancerous cells from chemotherapeutic agents
|
EP0722320B1
(de)
*
|
1993-10-08 |
2000-07-19 |
THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services |
Verwendung von stickstoffoxid freisetzenden verbindungen als arzneimittel zur strahlungssensibilisation fur hypoxische zellen
|
HU218280B
(en)
*
|
1994-04-26 |
2000-07-28 |
|
Cyclodextrin inclusion complexes containing sin-1a which are stable intheir solid state, process for their preparation and pharmaceutical compositions containing the comlexes
|
US6066333A
(en)
*
|
1994-09-22 |
2000-05-23 |
William Harvey Research Limited |
Pharmaceutical control of inflammation
|
CA2132690A1
(en)
*
|
1994-09-22 |
1996-03-23 |
Dean Willis |
Control and modulation of inflammatory response in humans in need of such control and modulation
|
US5700830A
(en)
*
|
1994-11-22 |
1997-12-23 |
The United States Of America As Represented By The Department Of Health And Human Services |
Use of nitric oxide-releasing agents for reducing metastasis risk
|
US5665077A
(en)
*
|
1995-04-24 |
1997-09-09 |
Nitrosci Pharmaceuticals Llc |
Nitric oxide-releasing nitroso compositions and methods and intravascular devices for using them to prevent restenosis
|
US5714511A
(en)
*
|
1995-07-31 |
1998-02-03 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Selective prevention of organ injury in sepsis and shock using selection release of nitric oxide in vulnerable organs
|
US5797887A
(en)
*
|
1996-08-27 |
1998-08-25 |
Novovasc Llc |
Medical device with a surface adapted for exposure to a blood stream which is coated with a polymer containing a nitrosyl-containing organo-metallic compound which releases nitric oxide from the coating to mediate platelet aggregation
|
EP0946160A4
(de)
*
|
1996-08-27 |
2007-05-09 |
Univ Akron |
Lipophile polyaminester zur ortsspezifischen abgabevon stickstoffmonoxid in pharmazeutischer anwendung
|
CA2266908C
(en)
*
|
1996-09-27 |
2010-07-20 |
Joseph E. Saavedra |
O2-arylated or o2-glycosylated 1-substituted diazen-1-ium-1,2-diolates and o2-substituted 1-[(2-carboxylato)pyrrolidin-1-yl]diazen-1-ium-1,2-diolates
|
EP1439187B1
(de)
*
|
1996-09-27 |
2013-12-18 |
THE UNITED STATES GOVERNMENT as represented by THE DEPARTMENT OF HEALTH AND HUMAN SERVICES |
O2-arylierte oder o2-glycosylierte 1-substituierte diazen-1-ium-1,2-diolate und o2-substituierte 1-(2-carboxylato)pyrrolidin-1-yl diazen-1-ium-1,2-diolate
|
US5958427A
(en)
*
|
1996-11-08 |
1999-09-28 |
Salzman; Andrew L. |
Nitric oxide donor compounds and pharmaceutical compositions for pulmonary hypertension and other indications
|
US6232336B1
(en)
*
|
1997-07-03 |
2001-05-15 |
The United States Of America As Represented By The Department Of Health And Human Services |
Nitric oxide-releasing amidine- and enamine-derived diazeniumdiolates, compositions and uses thereof and method of making same
|
US20040043068A1
(en)
*
|
1998-09-29 |
2004-03-04 |
Eugene Tedeschi |
Uses for medical devices having a lubricious, nitric oxide-releasing coating
|
US6261594B1
(en)
|
1998-11-25 |
2001-07-17 |
The University Of Akron |
Chitosan-based nitric oxide donor compositions
|
US6270779B1
(en)
*
|
2000-05-10 |
2001-08-07 |
United States Of America |
Nitric oxide-releasing metallic medical devices
|
WO2003006427A1
(en)
*
|
2001-07-12 |
2003-01-23 |
Johns Hopkins University |
Compounds that release nitric oxide at controlled rates upon photolysis
|
AU2002336761A1
(en)
*
|
2001-09-26 |
2003-04-07 |
The Government Of The United States Of America, Represented By The Secretary, Department Of Health A |
Nitric oxide-releasing coated medical devices and method of preparing same
|
US6703046B2
(en)
|
2001-10-04 |
2004-03-09 |
Medtronic Ave Inc. |
Highly cross-linked, extremely hydrophobic nitric oxide-releasing polymers and methods for their manufacture and use
|
GB0125222D0
(en)
*
|
2001-10-19 |
2001-12-12 |
Barts & London Nhs Trust |
Composition for the treatment of microbial infections
|
EP1490045B1
(de)
*
|
2002-03-21 |
2013-03-13 |
University of Utah Research Foundation |
In vivo Verwendung von durch Glutathionon s-Transferase aktivierten Stickoxid-Donatoren
|
EP1507526A2
(de)
*
|
2002-05-07 |
2005-02-23 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Polydiazeniumdiolierte cyclische polyamine mit polyphasischer stickoxid-freisetzung und verwandte verbindungen, diese enthaltende zusammensetzungen und anwendungsverfahren dafür
|
US7794743B2
(en)
|
2002-06-21 |
2010-09-14 |
Advanced Cardiovascular Systems, Inc. |
Polycationic peptide coatings and methods of making the same
|
US7056523B1
(en)
|
2002-06-21 |
2006-06-06 |
Advanced Cardiovascular Systems, Inc. |
Implantable medical devices incorporating chemically conjugated polymers and oligomers of L-arginine
|
US7217426B1
(en)
|
2002-06-21 |
2007-05-15 |
Advanced Cardiovascular Systems, Inc. |
Coatings containing polycationic peptides for cardiovascular therapy
|
US7033602B1
(en)
|
2002-06-21 |
2006-04-25 |
Advanced Cardiovascular Systems, Inc. |
Polycationic peptide coatings and methods of coating implantable medical devices
|
US6994867B1
(en)
|
2002-06-21 |
2006-02-07 |
Advanced Cardiovascular Systems, Inc. |
Biocompatible carrier containing L-arginine
|
US8506617B1
(en)
|
2002-06-21 |
2013-08-13 |
Advanced Cardiovascular Systems, Inc. |
Micronized peptide coated stent
|
US7011842B1
(en)
|
2002-06-21 |
2006-03-14 |
Advanced Cardiovascular Systems, Inc. |
Polycationic peptide coatings and methods of making the same
|
US7070798B1
(en)
|
2002-06-21 |
2006-07-04 |
Advanced Cardiovascular Systems, Inc. |
Coatings for implantable medical devices incorporating chemically-bound polymers and oligomers of L-arginine
|
WO2004012874A1
(en)
|
2002-08-02 |
2004-02-12 |
The Government Of The United States Of America, Represented By The Secretary, Dept. Of Health And Human Services |
Cross-linked nitric oxide-releasing polyamine coated substrates, compositions comprising same and method of making same
|
US7094256B1
(en)
|
2002-12-16 |
2006-08-22 |
Advanced Cardiovascular Systems, Inc. |
Coatings for implantable medical device containing polycationic peptides
|
AU2004257693B8
(en)
|
2003-07-09 |
2009-08-13 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of nitrite salts for the treatment of cardiovascular conditions
|
EP1691856A2
(de)
*
|
2003-10-14 |
2006-08-23 |
Cube Medical A/S |
Medizinprodukt mit elektrogesponnenen nanofasern
|
EP1718621A4
(de)
*
|
2004-01-30 |
2009-08-19 |
Univ Johns Hopkins |
Nitroxylvorläuferverbindungen anwendungsverfahren
|
US7829553B2
(en)
*
|
2004-02-09 |
2010-11-09 |
Amulet Pharmaceuticals, Inc. |
Nitric oxide-releasing polymers
|
US7362274B1
(en)
*
|
2004-07-09 |
2008-04-22 |
Huan-Cheng Lien |
Coupled feed-in butterfly shaped left/right hand circularly polarized microstrip antenna
|
EP1794195B1
(de)
|
2004-09-27 |
2014-12-17 |
Government of the United States of America, Represented by the Secretary, Department of Health and Human Services |
Stickoxidabgebende diazeniumdiolisierte acrylnitrilbasierte polymere und zusammensetzungen, medizinische vorrichtungen und verwendungen damit
|
US8557300B2
(en)
*
|
2005-05-19 |
2013-10-15 |
University Of Cincinnati |
Methods for treating bacterial respiratory tract infections in an individual using acidified nitrite
|
US8021679B2
(en)
|
2005-08-25 |
2011-09-20 |
Medtronic Vascular, Inc |
Nitric oxide-releasing biodegradable polymers useful as medical devices and coatings therefore
|
US20070053952A1
(en)
*
|
2005-09-07 |
2007-03-08 |
Medtronic Vascular, Inc. |
Nitric oxide-releasing polymers derived from modified polymers
|
WO2007053292A2
(en)
*
|
2005-10-31 |
2007-05-10 |
Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services |
Polysaccharide-derived nitric oxide-releasing carbon-bound diazeniumdiolates
|
US20070196327A1
(en)
*
|
2005-12-06 |
2007-08-23 |
Amulet Pharmaceuticals, Inc. |
Nitric oxide releasing polymers
|
US8241619B2
(en)
|
2006-05-15 |
2012-08-14 |
Medtronic Vascular, Inc. |
Hindered amine nitric oxide donating polymers for coating medical devices
|
US11229746B2
(en)
|
2006-06-22 |
2022-01-25 |
Excelsior Medical Corporation |
Antiseptic cap
|
US9259535B2
(en)
|
2006-06-22 |
2016-02-16 |
Excelsior Medical Corporation |
Antiseptic cap equipped syringe
|
US7862598B2
(en)
|
2007-10-30 |
2011-01-04 |
The Invention Science Fund I, Llc |
Devices and systems that deliver nitric oxide
|
US8221690B2
(en)
|
2007-10-30 |
2012-07-17 |
The Invention Science Fund I, Llc |
Systems and devices that utilize photolyzable nitric oxide donors
|
US7975699B2
(en)
|
2007-10-30 |
2011-07-12 |
The Invention Science Fund I, Llc |
Condoms configured to facilitate release of nitric oxide
|
US8642093B2
(en)
|
2007-10-30 |
2014-02-04 |
The Invention Science Fund I, Llc |
Methods and systems for use of photolyzable nitric oxide donors
|
US7811600B2
(en)
*
|
2007-03-08 |
2010-10-12 |
Medtronic Vascular, Inc. |
Nitric oxide donating medical devices and methods of making same
|
US8273828B2
(en)
|
2007-07-24 |
2012-09-25 |
Medtronic Vascular, Inc. |
Methods for introducing reactive secondary amines pendant to polymers backbones that are useful for diazeniumdiolation
|
US8980332B2
(en)
|
2007-10-30 |
2015-03-17 |
The Invention Science Fund I, Llc |
Methods and systems for use of photolyzable nitric oxide donors
|
US10080823B2
(en)
|
2007-10-30 |
2018-09-25 |
Gearbox Llc |
Substrates for nitric oxide releasing devices
|
US7846400B2
(en)
|
2007-10-30 |
2010-12-07 |
The Invention Science Fund I, Llc |
Substrates for nitric oxide releasing devices
|
US8877508B2
(en)
|
2007-10-30 |
2014-11-04 |
The Invention Science Fund I, Llc |
Devices and systems that deliver nitric oxide
|
US7897399B2
(en)
|
2007-10-30 |
2011-03-01 |
The Invention Science Fund I, Llc |
Nitric oxide sensors and systems
|
JP2011507968A
(ja)
*
|
2007-12-27 |
2011-03-10 |
エイヤーズ ファーマシューティカルズ、インク. |
エアロゾル化ニトライトおよび一酸化窒素供与性化合物ならびにそれらの使用
|
EP2244575B1
(de)
*
|
2008-01-24 |
2013-07-17 |
Merck Sharp & Dohme Corp. |
Angiotensin-ii-rezeptorantagonisten
|
US20090222088A1
(en)
*
|
2008-02-29 |
2009-09-03 |
Medtronic Vascular, Inc. |
Secondary Amine Containing Nitric Oxide Releasing Polymer Composition
|
JP5529762B2
(ja)
|
2008-03-07 |
2014-06-25 |
ユニバーシティー オブ ユタ リサーチ ファンデーション |
活性化一酸化窒素ドナーならびにその作製および使用方法
|
US20090232868A1
(en)
*
|
2008-03-17 |
2009-09-17 |
Medtronic Vascular, Inc. |
Nitric Oxide Releasing Polymer Composition
|
US20090232863A1
(en)
*
|
2008-03-17 |
2009-09-17 |
Medtronic Vascular, Inc. |
Biodegradable Carbon Diazeniumdiolate Based Nitric Oxide Donating Polymers
|
US9078992B2
(en)
|
2008-10-27 |
2015-07-14 |
Pursuit Vascular, Inc. |
Medical device for applying antimicrobial to proximal end of catheter
|
US8158187B2
(en)
*
|
2008-12-19 |
2012-04-17 |
Medtronic Vascular, Inc. |
Dry diazeniumdiolation methods for producing nitric oxide releasing medical devices
|
US8709465B2
(en)
*
|
2009-04-13 |
2014-04-29 |
Medtronic Vascular, Inc. |
Diazeniumdiolated phosphorylcholine polymers for nitric oxide release
|
US20110160200A1
(en)
*
|
2009-11-23 |
2011-06-30 |
Cardioxyl Pharmaceuticals, Inc. |
Nitroxyl Progenitors for the Treatment of Pulmonary Hypertension
|
US9023890B2
(en)
*
|
2009-12-02 |
2015-05-05 |
The Charlotte-Mecklenburg Hospital Authority |
Nitrate esters and their use for the treatment of muscle and muscle related diseases
|
AU2011215881A1
(en)
*
|
2010-02-12 |
2012-07-26 |
Merck Sharp & Dohme Corp. |
Diazeniumdiolate cyclopentyl derivatives
|
WO2011115804A1
(en)
|
2010-03-17 |
2011-09-22 |
Ironwood Pharmaceuticals, Inc. |
Sgc stimulators
|
US20110301299A1
(en)
|
2010-06-08 |
2011-12-08 |
Medtronic Vascular, Inc. |
Medical Devices and Polymers Therefor Having PTFE Surfaces Modified With Nitric Oxide-Releasing Polymers
|
TWI582091B
(zh)
|
2010-06-30 |
2017-05-11 |
艾諾屋製藥公司 |
可溶性鳥苷酸環化酶(sGC)刺激物
|
CN103347385A
(zh)
*
|
2010-10-29 |
2013-10-09 |
默沙东公司 |
二醇二氮烯鎓类杂环衍生物
|
MX341531B
(es)
|
2010-11-09 |
2016-08-22 |
Ironwood Pharmaceuticals Inc |
Derivados de triazol como estimuladores de la guanilato ciclasa soluble gcs.
|
JO3350B1
(ar)
*
|
2011-03-07 |
2019-03-13 |
Merck Sharp & Dohme |
مشتقات حلقية غير متجانسة محتوية على مجموعات أمينو أولية ومركبات داي أزينيومديولات
|
US9452117B2
(en)
|
2011-06-01 |
2016-09-27 |
The Charlotte-Mecklenburg Hospital Authority |
Nitrate esters and their use for the treatment of muscle and muscle related diseases
|
CN103796704B
(zh)
|
2011-07-12 |
2016-12-07 |
***瓦勒公司 |
用于将抗微生物剂递送到经皮导管中的装置
|
CN104066731B
(zh)
|
2011-12-27 |
2016-06-15 |
铁木医药有限公司 |
可用作sgc刺激剂的2-苄基、3-(嘧啶-2-基)取代的吡唑类
|
US9309235B2
(en)
|
2012-09-18 |
2016-04-12 |
Ironwood Pharmaceuticals, Inc. |
SGC stimulators
|
EP2897953B8
(de)
|
2012-09-19 |
2019-06-26 |
Cyclerion Therapeutics, Inc. |
Sgc-stimulatoren
|
CN108912111B
(zh)
|
2013-03-15 |
2021-09-14 |
赛克里翁治疗有限公司 |
化合物及药用组合物
|
JP2016540017A
(ja)
|
2013-12-11 |
2016-12-22 |
アイアンウッド ファーマシューティカルズ インコーポレイテッド |
sGC刺激物質
|
WO2015106268A1
(en)
|
2014-01-13 |
2015-07-16 |
Ironwood Pharmaceuticals, Inc. |
USE OF sGC STIMULATORS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS
|
US10046156B2
(en)
|
2014-05-02 |
2018-08-14 |
Excelsior Medical Corporation |
Strip package for antiseptic cap
|
US20170298055A1
(en)
|
2014-09-17 |
2017-10-19 |
Ironwood Pharmaceuticals, Inc. |
sGC STIMULATORS
|
CA2959757A1
(en)
|
2014-09-17 |
2016-03-24 |
Ironwood Pharmaceuticals, Inc. |
Pyrazole derivatives as sgc stimulators
|
AU2015317823A1
(en)
|
2014-09-17 |
2017-03-23 |
Ironwood Pharmaceuticals, Inc. |
sGC stimulators
|
JP6822978B2
(ja)
|
2015-05-08 |
2021-01-27 |
アイシーユー・メディカル・インコーポレーテッド |
治療薬のエミッタを受け入れるように構成された医療用コネクタ
|
CN114736240A
(zh)
|
2016-07-07 |
2022-07-12 |
赛克里翁治疗有限公司 |
sGC刺激剂的磷前药
|
KR20230074840A
(ko)
|
2016-07-07 |
2023-05-31 |
사이클리온 테라퓨틱스, 인크. |
sGC 자극제의 고체 형태
|
WO2018071717A1
(en)
|
2016-10-14 |
2018-04-19 |
Icu Medical, Inc. |
Sanitizing caps for medical connectors
|
WO2018204206A2
(en)
|
2017-05-01 |
2018-11-08 |
Icu Medical, Inc. |
Medical fluid connectors and methods for providing additives in medical fluid lines
|
US11541221B2
(en)
|
2018-11-07 |
2023-01-03 |
Icu Medical, Inc. |
Tubing set with antimicrobial properties
|
US11534595B2
(en)
|
2018-11-07 |
2022-12-27 |
Icu Medical, Inc. |
Device for delivering an antimicrobial composition into an infusion device
|
US11517732B2
(en)
|
2018-11-07 |
2022-12-06 |
Icu Medical, Inc. |
Syringe with antimicrobial properties
|
US11400195B2
(en)
|
2018-11-07 |
2022-08-02 |
Icu Medical, Inc. |
Peritoneal dialysis transfer set with antimicrobial properties
|
US11541220B2
(en)
|
2018-11-07 |
2023-01-03 |
Icu Medical, Inc. |
Needleless connector with antimicrobial properties
|
CA3118905A1
(en)
|
2018-11-21 |
2020-05-28 |
Icu Medical, Inc. |
Antimicrobial device comprising a cap with ring and insert
|
AU2021396147A1
(en)
|
2020-12-07 |
2023-06-29 |
Icu Medical, Inc. |
Peritoneal dialysis caps, systems and methods
|