DE69212468D1 - Gerät zur verminderung der empfindung während der iontophoretischen arneimittelverabreichung - Google Patents

Gerät zur verminderung der empfindung während der iontophoretischen arneimittelverabreichung

Info

Publication number
DE69212468D1
DE69212468D1 DE69212468T DE69212468T DE69212468D1 DE 69212468 D1 DE69212468 D1 DE 69212468D1 DE 69212468 T DE69212468 T DE 69212468T DE 69212468 T DE69212468 T DE 69212468T DE 69212468 D1 DE69212468 D1 DE 69212468D1
Authority
DE
Germany
Prior art keywords
drug administration
sensation
sensitivity during
iontophoretic drug
reducing sensitivity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69212468T
Other languages
English (en)
Other versions
DE69212468T2 (de
Inventor
J Phipps
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Alza Corp
Original Assignee
Alza Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alza Corp filed Critical Alza Corp
Application granted granted Critical
Publication of DE69212468D1 publication Critical patent/DE69212468D1/de
Publication of DE69212468T2 publication Critical patent/DE69212468T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Radiology & Medical Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Electrotherapy Devices (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Electrostatic Spraying Apparatus (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69212468T 1991-04-02 1992-03-30 Gerät zur verminderung der empfindung während der iontophoretischen arneimittelverabreichung Expired - Lifetime DE69212468T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/679,425 US5221254A (en) 1991-04-02 1991-04-02 Method for reducing sensation in iontophoretic drug delivery
PCT/US1992/002588 WO1992017239A1 (en) 1991-04-02 1992-03-30 Device for reducing sensation during iontophoretic drug delivery

Publications (2)

Publication Number Publication Date
DE69212468D1 true DE69212468D1 (de) 1996-08-29
DE69212468T2 DE69212468T2 (de) 1996-12-12

Family

ID=24726864

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69212468T Expired - Lifetime DE69212468T2 (de) 1991-04-02 1992-03-30 Gerät zur verminderung der empfindung während der iontophoretischen arneimittelverabreichung

Country Status (12)

Country Link
US (2) US5221254A (de)
EP (1) EP0578773B1 (de)
JP (1) JP3343348B2 (de)
AT (1) ATE140630T1 (de)
AU (1) AU1773792A (de)
DE (1) DE69212468T2 (de)
ES (1) ES2089532T3 (de)
IE (1) IE921009A1 (de)
MX (1) MX9201439A (de)
PT (1) PT100323B (de)
WO (1) WO1992017239A1 (de)
ZA (1) ZA922298B (de)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5221254A (en) * 1991-04-02 1993-06-22 Alza Corporation Method for reducing sensation in iontophoretic drug delivery
AU689438B2 (en) * 1991-12-30 1998-04-02 Azur Pharma International Limited Methods of producing analgesia and enhancing opiate analgesia
WO1995009032A1 (en) * 1993-09-30 1995-04-06 Becton, Dickinson And Company Iontophoretic drug delivery system and method
US5540669A (en) * 1993-09-30 1996-07-30 Becton, Dickinson And Company Iontophoretic drug delivery system and method for using same
DK0752898T3 (da) * 1994-03-30 1999-02-15 Alza Corp Mindskning af hudirritation ved elektrotransport-tilførsel
US5498235A (en) * 1994-09-30 1996-03-12 Becton Dickinson And Company Iontophoresis assembly including patch/controller attachment
US5861439A (en) * 1994-11-14 1999-01-19 Alza Corporation Method for enhanced electrotransport agent delivery
US5611594A (en) * 1995-04-13 1997-03-18 Findlay; Robert Portable folding chair
EP0920345A4 (de) * 1996-06-19 2006-05-10 Vyteris Inc Iontophoretische abscheidung von zelladhäsions-inhibitoren
US6157858A (en) * 1996-12-26 2000-12-05 Elan Pharma International Limited Device for the delivery of a substance to a subject and improved electrode assembly
EP0964722B1 (de) * 1996-12-26 2004-09-01 Elan International Services Limited Elektrodeneinheit für eine vorrichtung zur verabreichung von medikamenten
US6018679A (en) 1997-01-29 2000-01-25 Novartis Finance Corp. Iontophoretic transdermal delivery and control of adverse side-effects
JP3366548B2 (ja) * 1997-02-26 2003-01-14 久光製薬株式会社 イオントフォレーシス用デバイス構造体及びその製造方法
US6119036A (en) 1997-03-26 2000-09-12 The Board Of Regents Of The University Of Oklahoma Iontophoretic transdermal delivery device
EP0898962A1 (de) * 1997-08-28 1999-03-03 Becton, Dickinson and Company Transdermale Pflaster und Verfahren zur Inaktivierung von Hautproteasen
KR100315160B1 (ko) * 1998-01-09 2002-05-13 김충섭 피부수렴제가첨가된경피투여용약제조성물
DE69933780T2 (de) * 1998-08-31 2007-09-13 Travanti Pharma Inc. Gesteuerte medikamentdosierungsvorrichtung
US6475514B1 (en) * 1998-12-03 2002-11-05 Andrew Blitzer Athletic patch
US6421561B1 (en) 1999-12-30 2002-07-16 Birch Point Medical, Inc. Rate adjustable drug delivery system
US6653014B2 (en) 2001-05-30 2003-11-25 Birch Point Medical, Inc. Power sources for iontophoretic drug delivery systems
WO2004032963A2 (en) * 2002-10-04 2004-04-22 Photokinetix Inc. Photokinetic delivery of biologically active substances using pulsed incoherent light
US7220778B2 (en) * 2003-04-15 2007-05-22 The General Hospital Corporation Methods and devices for epithelial protection during photodynamic therapy
CA2580329C (en) 2004-09-13 2015-01-06 Chrono Therapeutics Inc. Biosynchronous transdermal drug delivery
US8252321B2 (en) 2004-09-13 2012-08-28 Chrono Therapeutics, Inc. Biosynchronous transdermal drug delivery for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and the treatment of hyperglycemia, alzheimer's disease, sleep disorders, parkinson's disease, aids, epilepsy, attention deficit disorder, nicotine addiction, cancer, headache and pain control, asthma, angina, hypertension, depression, cold, flu and the like
US20070042026A1 (en) * 2005-03-17 2007-02-22 Wille John J Prophylactic and therapeutic treatment of topical and transdermal drug-induced skin reactions
WO2006127905A2 (en) 2005-05-24 2006-11-30 Chrono Therapeutics, Inc. Portable drug delivery device
US20080193514A1 (en) * 2006-11-02 2008-08-14 Transcu Ltd. Compostions and methods for iontophoresis delivery of active ingredients through hair follicles
EP2123259A1 (de) * 2007-01-16 2009-11-25 Hokkaido University Liposom-zubereitung für die iontophorese mit einem darin eingekapselten antioxidans-bestandteil
US20080188791A1 (en) * 2007-02-02 2008-08-07 Difiore Attilio E Active iontophoresis delivery system
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
JP2010187707A (ja) * 2007-06-12 2010-09-02 Hokkaido Univ インスリンを封入したイオントフォレーシス用リポソーム製剤
EP2164418B1 (de) * 2007-06-27 2014-01-08 The General Hospital Corporation Vorrichtung zur optischen unterdrückung einer photodynamischen therapie
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
US8989875B2 (en) 2010-09-21 2015-03-24 Koninklijke Philips N.V. Electrode apparatus
WO2013006643A1 (en) 2011-07-06 2013-01-10 The Parkinson's Institute Compositions and methods for treatment of symptoms in parkinson's disease patients
US10105487B2 (en) 2013-01-24 2018-10-23 Chrono Therapeutics Inc. Optimized bio-synchronous bioactive agent delivery system
AU2016211330A1 (en) 2015-01-28 2017-08-03 Chrono Therapeutics Inc. Drug delivery methods and systems
WO2016145373A1 (en) 2015-03-12 2016-09-15 Chrono Therapeutics Inc. Craving input and support system
US20180049681A1 (en) * 2016-08-19 2018-02-22 University Of Cincinnati Methods and materials for prolonged sweat stimulation
EP3565617A1 (de) 2017-01-06 2019-11-13 Chrono Therapeutics Inc. Vorrichtungen und verfahren zur transdermalen wirkstofffreisetzung
US11596779B2 (en) 2018-05-29 2023-03-07 Morningside Venture Investments Limited Drug delivery methods and systems

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE399044A (de) * 1933-09-09
US3991755A (en) * 1973-07-27 1976-11-16 Medicon, Inc. Iontophoresis apparatus for applying local anesthetics
US3989816A (en) * 1975-06-19 1976-11-02 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloheptan-2-ones
US4405616A (en) * 1975-06-19 1983-09-20 Nelson Research & Development Company Penetration enhancers for transdermal drug delivery of systemic agents
US4141359A (en) * 1976-08-16 1979-02-27 University Of Utah Epidermal iontophoresis device
US4211222A (en) * 1976-08-25 1980-07-08 Robert Tapper Iontophoretic burn-protection method
US4340047A (en) * 1978-10-18 1982-07-20 Robert Tapper Iontophoretic treatment apparatus
US4250878A (en) * 1978-11-22 1981-02-17 Motion Control, Inc. Non-invasive chemical species delivery apparatus and method
WO1981000964A1 (en) * 1979-10-10 1981-04-16 Cyclotech Med Ind Pain blocking bandage
US4424210A (en) * 1980-04-04 1984-01-03 Nelson Research & Development Company Vehicle composition containing 1-substituted azacycloalkan-2-ones
US4415563A (en) * 1980-04-04 1983-11-15 Nelson Research & Development Company Vehicle composition containing 1-substituted azacyclononan-2-ones
US4382529A (en) * 1980-12-15 1983-05-10 Drdlik Frank J Sanitary dispensing closure
US4416274A (en) * 1981-02-23 1983-11-22 Motion Control, Inc. Ion mobility limiting iontophoretic bioelectrode
US4406658A (en) * 1981-03-06 1983-09-27 Medtronic, Inc. Iontophoretic device with reversible polarity
US4747819A (en) * 1984-10-29 1988-05-31 Medtronic, Inc. Iontophoretic drug delivery
US4744787A (en) * 1984-10-29 1988-05-17 Medtronic, Inc. Iontophoresis apparatus and methods of producing same
ATE74523T1 (de) * 1984-12-07 1992-04-15 Faruk Hadziselimovic Praeparat zur intramuskulaeren injektion von medikamenten, vitaminen oder impfstoffen.
DE3507301A1 (de) * 1985-03-01 1986-09-04 Arbo GmbH Medizin-Technologie, 38100 Braunschweig Bioelektrische elektrode
BR8507220A (pt) * 1985-06-10 1987-08-04 Drug Delivery Systems Inc Sistema e processo para controlar o regime de ministracao eletrocinetica de uma droga
US4722726A (en) * 1986-02-12 1988-02-02 Key Pharmaceuticals, Inc. Method and apparatus for iontophoretic drug delivery
US4752285B1 (en) * 1986-03-19 1995-08-22 Univ Utah Res Found Methods and apparatus for iontophoresis application of medicaments
IE60941B1 (en) * 1986-07-10 1994-09-07 Elan Transdermal Ltd Transdermal drug delivery device
DE3703321A1 (de) * 1986-09-01 1988-03-10 Transcutan Gmbh Therapievorrichtung zur anwendung von elektrischem strom
US4822334A (en) * 1986-12-04 1989-04-18 Robert Tapper Electrical dosimetry control system
FR2616333A1 (fr) * 1987-06-12 1988-12-16 Cird Procede d'ionophorese pour administrer une substance dissoute ou partiellement dissoute, par voie percutanee ou perungueale et dispositif correspondant
EP0318776A1 (de) * 1987-12-04 1989-06-07 Robert Tapper Verfahren und Gerät zur Verminderung des Hautverletzung bei Gebrauch von Elektroden
US5006108A (en) * 1988-11-16 1991-04-09 Noven Pharmaceuticals, Inc. Apparatus for iontophoretic drug delivery
US4992508A (en) * 1989-06-16 1991-02-12 Imaginative Research Associates, Inc. Aqueous dispersions of polyester and polyesteramides cross-linked with metallic ions and casts made therefrom
US5167616A (en) * 1989-12-14 1992-12-01 Alza Corporation Iontophoretic delivery method
US5221254A (en) * 1991-04-02 1993-06-22 Alza Corporation Method for reducing sensation in iontophoretic drug delivery
US5246418A (en) * 1991-12-17 1993-09-21 Becton Dickinson And Company Iontophresis system having features for reducing skin irritation

Also Published As

Publication number Publication date
AU1773792A (en) 1992-11-02
WO1992017239A1 (en) 1992-10-15
DE69212468T2 (de) 1996-12-12
JP3343348B2 (ja) 2002-11-11
PT100323A (pt) 1994-04-29
ES2089532T3 (es) 1996-10-01
JPH06506616A (ja) 1994-07-28
MX9201439A (es) 1992-10-01
ZA922298B (en) 1993-01-27
EP0578773B1 (de) 1996-07-24
ATE140630T1 (de) 1996-08-15
EP0578773A1 (de) 1994-01-19
US5403275A (en) 1995-04-04
US5221254A (en) 1993-06-22
PT100323B (pt) 1999-04-30
IE921009A1 (en) 1992-10-07

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Legal Events

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8364 No opposition during term of opposition