DE69131426T2 - Neue wasserlösliche polypeptide mit hoher affinität für alpha- und beta- interferone - Google Patents

Neue wasserlösliche polypeptide mit hoher affinität für alpha- und beta- interferone

Info

Publication number
DE69131426T2
DE69131426T2 DE69131426T DE69131426T DE69131426T2 DE 69131426 T2 DE69131426 T2 DE 69131426T2 DE 69131426 T DE69131426 T DE 69131426T DE 69131426 T DE69131426 T DE 69131426T DE 69131426 T2 DE69131426 T2 DE 69131426T2
Authority
DE
Germany
Prior art keywords
high affinity
alpha
soluble polypeptides
new water
beta interferon
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69131426T
Other languages
English (en)
Other versions
DE69131426D1 (de
Inventor
Pierre Eid
Ion Gresser
Georges Lutfalla
Francois Meyer
Knud Mogensen
Michael Tovey
Gilles Uze
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medisup International NV
Original Assignee
Medisup International NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25675747&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69131426(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Medisup International NV filed Critical Medisup International NV
Application granted granted Critical
Publication of DE69131426D1 publication Critical patent/DE69131426D1/de
Publication of DE69131426T2 publication Critical patent/DE69131426T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69131426T 1991-04-17 1991-04-17 Neue wasserlösliche polypeptide mit hoher affinität für alpha- und beta- interferone Expired - Fee Related DE69131426T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CA002085469A CA2085469C (fr) 1991-04-17 1991-04-17 Polypeptides hydrosolubles ayant une haute affinite pour les interferons .alpha. et .beta.
PCT/FR1991/000318 WO1992018626A1 (fr) 1991-04-17 1991-04-17 POLYPEPTIDES HYDROSOLUBLES AYANT UNE HAUTE AFFINITE POUR LES INTERFERONS α ET $g(b)

Publications (2)

Publication Number Publication Date
DE69131426D1 DE69131426D1 (de) 1999-08-12
DE69131426T2 true DE69131426T2 (de) 2000-01-27

Family

ID=25675747

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69131426T Expired - Fee Related DE69131426T2 (de) 1991-04-17 1991-04-17 Neue wasserlösliche polypeptide mit hoher affinität für alpha- und beta- interferone

Country Status (12)

Country Link
US (1) US6475983B1 (de)
EP (1) EP0537166B1 (de)
JP (1) JPH05507614A (de)
KR (1) KR0172969B1 (de)
AT (1) ATE181961T1 (de)
AU (1) AU653937B2 (de)
CA (2) CA2085469C (de)
DE (1) DE69131426T2 (de)
DK (1) DK0537166T3 (de)
ES (1) ES2133285T3 (de)
GR (1) GR3031369T3 (de)
WO (1) WO1992018626A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0563487A1 (de) * 1992-03-31 1993-10-06 Laboratoire Europeen De Biotechnologie S.A. Monoklonale Antikörper gegen den Interferonrezeptor, mit neutralisierender Aktivität gegen Typ I-Interferon
IL108584A (en) * 1994-02-07 2008-03-20 Yeda Res & Dev Cloning of the interferon-binding protein ALPHA / BETA
US5821078A (en) * 1992-09-03 1998-10-13 Yeda Research And Development Co. Ltd. Nucleic acid encoding interferon-α/β binding protein
IL107378A (en) * 1993-10-24 2005-05-17 Yeda Res & Dev SOLUBLE INTERFERON alpha-RECEPTOR, ITS PREPARATION AND USE
AU4411699A (en) * 1998-06-05 1999-12-20 Human Genome Sciences, Inc. Interferon receptor hkaef92
AU3725600A (en) * 1999-03-02 2000-09-21 Maxygen, Inc. Surrogate orphan ligands for orphan receptors
DE60239522D1 (de) * 2001-01-09 2011-05-05 Baylor Res Inst Dallas Verfahren zur behandlung von autoimmunerkrankungen bei einem probanden und diagnostische in-vitro-assays
US20050176108A1 (en) * 2003-03-13 2005-08-11 Young-Min Kim Physiologically active polypeptide conjugate having prolonged in vivo half-life
US20040180054A1 (en) * 2003-03-13 2004-09-16 Hanmi Pharm. Co., Ltd. Physiologically active polypeptide conjugate having prolonged in vivo half-life
ATE522548T1 (de) * 2003-11-13 2011-09-15 Hanmi Holdings Co Ltd Verfahren zur massenproduktion der konstanten region von immunglobulin
CA2546054C (en) * 2003-12-10 2014-05-13 Medarex, Inc. Interferon alpha antibodies and their uses
KR101363120B1 (ko) * 2005-02-10 2014-02-13 베일러 리서치 인스티튜트 항-인터페론 알파 모노클로날 항체 및 사용 방법
US7888481B2 (en) * 2005-02-10 2011-02-15 Baylor Research Institute Anti-interferon alpha monoclonal antibodies and methods for use
US7732167B2 (en) * 2005-06-17 2010-06-08 Regeneron Pharmaceuticals, Inc. Interferon-α/β binding fusion proteins and therapeutic uses thereof
WO2009135861A2 (en) * 2008-05-07 2009-11-12 Novo Nordisk A/S Humanized antibodies against human interferon-alpha
AU2018321359B2 (en) * 2017-08-22 2023-11-30 Sanabio, Llc Soluble interferon receptors and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5516515A (en) * 1986-02-05 1996-05-14 Interferon Sciences, Inc. Separation of alpha interferon receptor proteins and antibodies therefor
US5216128A (en) * 1989-06-01 1993-06-01 Yeda Research And Development Co., Ltd. IFN-β2/IL-6 receptor its preparation and pharmaceutical compositions containing it
US5395760A (en) * 1989-09-05 1995-03-07 Immunex Corporation DNA encoding tumor necrosis factor-α and -β receptors
IL91562A0 (en) * 1989-09-07 1990-04-29 Yeda Res & Dev Interferon-gamma receptor fragment and its production
US5889151A (en) * 1989-10-20 1999-03-30 Societe Leb-Tech Purified human alpha interferon receptor
FR2657881A1 (fr) * 1990-02-05 1991-08-09 Europ Biotechnologie Lab Nouveaux polypeptides hydrosolubles, sequences d'adn, nouvelles cellules, procede de preparation, applications et compositions renfermant lesdits polypeptides.
US5218090A (en) * 1990-06-12 1993-06-08 Warner-Lambert Company EGF receptor truncates
IL107378A (en) * 1993-10-24 2005-05-17 Yeda Res & Dev SOLUBLE INTERFERON alpha-RECEPTOR, ITS PREPARATION AND USE

Also Published As

Publication number Publication date
EP0537166B1 (de) 1999-07-07
WO1992018626A1 (fr) 1992-10-29
JPH05507614A (ja) 1993-11-04
CA2085469C (fr) 2007-07-31
ES2133285T3 (es) 1999-09-16
EP0537166A1 (de) 1993-04-21
KR0172969B1 (ko) 1999-02-01
CA2585487A1 (fr) 1992-10-29
DE69131426D1 (de) 1999-08-12
DK0537166T3 (da) 1999-11-22
CA2085469A1 (fr) 1992-10-18
AU7792791A (en) 1992-11-17
AU653937B2 (en) 1994-10-20
GR3031369T3 (en) 2000-01-31
US6475983B1 (en) 2002-11-05
ATE181961T1 (de) 1999-07-15

Similar Documents

Publication Publication Date Title
DE69131426D1 (de) Neue wasserlösliche polypeptide mit hoher affinität für alpha- und beta- interferone
EE200100223A (et) Interferoon-beetaga sulandatud valgud ja nende kasutamine
IT8223795A0 (it) Gamma), relativi veicoli di polipeptidi contenenti la sequenza espressione, loro procedimento di degli amminoacidi dell'interferone preparazione, composizioni umano immune (interferone umano farmaceutiche contenenti tali polipeptidi.
IT8367525A0 (it) Proteina ibrida comprendente frammenti proteici collegati da legami peptidici e relativo gene di fusione composizione contenente tale proteina
DE3485693D1 (de) Menschlicher, insulinaehnlicher wachstumsfaktor (igf)hergestellt aus einem rekombinanten wirt, verfahren, expressionsvektor und rekombinanter wirt hierfuer und igf enthaltende pharmazeutische zusammensetzung.
DK0436005T3 (da) Mærkede polypeptidderivater
DK0673420T3 (da) Mammale receptorer for interleukin 10 (IL-10)
ES8103976A1 (es) Un metodo de producir proteinas de interferon humano de for-ma le
ATE56728T1 (de) Neue polypeptide mit alpha-amylase-hemmender wirkung, verfahren zu deren herstellung, deren verwendung und pharmazeutische praeparate.
ATE123949T1 (de) B-ketten-analoge des von blutplättchen abstammenden wachstumsfaktors und verfahren zu deren homogener herstellung.
DE3650322D1 (de) Fusionsproteine aus Interleukin-2 und Hirudin.
HUT46061A (en) Dna sequences encoding hirudin-like protein and process for producing such proteins
DE69132545D1 (de) Protein mit Cytokinaktivität, Rekombinant-DNS, Expressionsvektor und Wirtszellen zu seiner Herstellung
AU7017494A (en) Purified mammalian flt3 ligands and agonists and antagonists thereof
NO922421L (no) Collagenbindende protein, samt fremstilling derav
DE3782549D1 (de) Neue polypeptide, ihre herstellung und ihre verwendung.
ATE254179T1 (de) Neue type-i-interferon varianten, ihre verfahren zur herstellung, und ihre verwendungen
DE3685044D1 (de) Analoge interferon-polypeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
IL92316A0 (en) Recombinant interleukin-2 hybrid proteins,their production and pharmaceutical compositions containing them
ATE291629T1 (de) Expressionssystem für die sekretion von bioaktivem, menschlichem granulozyt-makrophagem koloniestimulierungsfaktor (gm-csf) und anderen heterologen proteinen aus streptomyces
ATE111920T1 (de) Lymphokine, dns-sequenzen, die diese lymphokine kodieren, und sie enthaltende pharmazeutische zusammensetzungen.
KR890013177A (ko) 신규폴리펩티드 및 그것을 코우드하는 dna
ATE342972T1 (de) Ifn rezeptor 1 bindende proteine, dafür kodierende dna und verfahren zur regulierung der zellulären antwort auf interferone
ATE105570T1 (de) Modifizierte menschliche anti-rh(d)-antikoerper.
RU92016519A (ru) Полипептид, днк, клетка, способ получения полипептида, лекарственное средство, фармацевтическая композиция, применение полипептида

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: MEISSNER, BOLTE & PARTNER GBR, 80538 MUENCHEN

8339 Ceased/non-payment of the annual fee