DE69124721D1 - Carbostyrilderivate und diese enthaltende pharmazeutische Zusammensetzungen - Google Patents

Carbostyrilderivate und diese enthaltende pharmazeutische Zusammensetzungen

Info

Publication number
DE69124721D1
DE69124721D1 DE69124721T DE69124721T DE69124721D1 DE 69124721 D1 DE69124721 D1 DE 69124721D1 DE 69124721 T DE69124721 T DE 69124721T DE 69124721 T DE69124721 T DE 69124721T DE 69124721 D1 DE69124721 D1 DE 69124721D1
Authority
DE
Germany
Prior art keywords
pharmaceutical compositions
compositions containing
carbostyril derivatives
carbostyril
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69124721T
Other languages
English (en)
Other versions
DE69124721T2 (de
Inventor
Hidenori Ogawa
Hisashi Miyamoto
Kazumi Kondo
Hiroshi Yamashita
Kenji Nakaya
Hajime Komatsu
Michinori Tanaka
Kazuyoshi Kitano
Takafumi Fujioka
Shuji Teramoto
Michiaki Tominaga
Yoichi Yabuuchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Publication of DE69124721D1 publication Critical patent/DE69124721D1/de
Application granted granted Critical
Publication of DE69124721T2 publication Critical patent/DE69124721T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
DE69124721T 1990-08-07 1991-08-02 Carbostyrilderivate und diese enthaltende pharmazeutische Zusammensetzungen Expired - Lifetime DE69124721T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP21002590 1990-08-07

Publications (2)

Publication Number Publication Date
DE69124721D1 true DE69124721D1 (de) 1997-03-27
DE69124721T2 DE69124721T2 (de) 1997-07-17

Family

ID=16582572

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69124721T Expired - Lifetime DE69124721T2 (de) 1990-08-07 1991-08-02 Carbostyrilderivate und diese enthaltende pharmazeutische Zusammensetzungen

Country Status (10)

Country Link
US (1) US5300513A (de)
EP (1) EP0470514B1 (de)
JP (1) JP3165867B2 (de)
KR (1) KR960001722B1 (de)
CN (1) CN1036651C (de)
AU (1) AU638346B2 (de)
DE (1) DE69124721T2 (de)
DK (1) DK0470514T3 (de)
ES (1) ES2100187T3 (de)
TW (1) TW199153B (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3959893A (en) * 1992-04-24 1993-11-29 Smithkline Beecham Plc N-aryloxy(thio)alkyl-azacycloalkanes useful as calcium channel antagonists
CA2116334A1 (en) * 1992-07-02 1994-01-20 Hidenori Ogawa Oxytocin antagonist
TW250481B (de) * 1992-08-20 1995-07-01 Otsuka Pharma Co Ltd
US5356904A (en) * 1992-10-07 1994-10-18 Merck & Co., Inc. Carbostyril oxytocin receptor antagonists
ATE216580T1 (de) * 1993-07-16 2002-05-15 Merck & Co Inc Benzoxazinon- und benzopyrimidinon- piperidinyl- verbindungen als tokolytische oxytocin-rezeptor- antagonisten
US5693635A (en) * 1993-07-29 1997-12-02 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
US5843952A (en) * 1993-07-29 1998-12-01 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
US5733905A (en) * 1993-07-29 1998-03-31 American Cyanamid Company Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
US5686445A (en) * 1993-07-29 1997-11-11 American Cyanamid Company Pyridobenzoxazepine and pyridobenzothiazepine vasopressin antagonists
US5736540A (en) * 1993-07-29 1998-04-07 American Cyanamid Company Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
US5968930A (en) * 1993-07-29 1999-10-19 American Cyanamid Company Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
US5736538A (en) * 1993-07-29 1998-04-07 American Cyanamid Company Tricyclic Benzazepine vasopressin antagonists
US5747487A (en) * 1993-07-29 1998-05-05 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
US5760031A (en) * 1993-07-29 1998-06-02 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
US5516774A (en) * 1993-07-29 1996-05-14 American Cyanamid Company Tricyclic diazepine vasopressin antagonists and oxytocin antagonists
US5739128A (en) * 1993-07-29 1998-04-14 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
US5869483A (en) * 1993-07-29 1999-02-09 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
US5512563A (en) * 1993-07-29 1996-04-30 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
FR2708608B1 (fr) * 1993-07-30 1995-10-27 Sanofi Sa Dérivés de N-sulfonylbenzimidazolone, leur préparation, les compositions pharmaceutiques en contenant.
US5464788A (en) * 1994-03-24 1995-11-07 Merck & Co., Inc. Tocolytic oxytocin receptor antagonists
US5696112A (en) * 1995-01-17 1997-12-09 American Cyanamid Company Fused heterocyclic azepines as vasopressin antagonists
US5700796A (en) * 1995-01-17 1997-12-23 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
US5849735A (en) * 1995-01-17 1998-12-15 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
US5753648A (en) * 1995-01-17 1998-05-19 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
US5536718A (en) * 1995-01-17 1996-07-16 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
US5521173A (en) * 1995-01-17 1996-05-28 American Home Products Corporation Tricyclic benzazepine vasopressin antagonists
US5532235A (en) * 1995-01-17 1996-07-02 American Cyanamid Company Tricyclic benzazepine vasopressin antagonists
EP0805681A4 (de) * 1995-01-24 1998-05-06 Merck & Co Inc Tokolytische oxytocin-rezeptor-antagonisten
CA2155623C (en) * 1995-08-08 2003-12-30 Gilles Roy Incandescent lamp having a lifetime extended by two rectifying diodes and a resistor
US5726172A (en) * 1996-01-16 1998-03-10 Merck & Co., Inc. Tocolytic oxytocin receptor antagonists
US5756497A (en) * 1996-03-01 1998-05-26 Merck & Co., Inc. Tocolytic oxytocin receptor antagonists
WO1999038533A1 (fr) 1998-01-28 1999-08-05 Senju Pharmaceutical Co., Ltd. Mesures prophylactiques ou remedes contre les troubles de la vision
GB9914825D0 (en) * 1999-06-24 1999-08-25 Smithkline Beecham Spa Novel compounds
CA2389439A1 (en) 1999-11-04 2001-05-10 Ortho-Mcneil Pharmaceutical, Inc. Nonpeptide substituted benzothiazepines as vasopressin antagonists
US7326700B2 (en) 2001-04-12 2008-02-05 Wyeth Cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
US7022699B2 (en) 2001-04-12 2006-04-04 Wyeth Cyclohexenyl phenyl diazepines vasopressin and oxytocin receptor modulators
US7064120B2 (en) 2001-04-12 2006-06-20 Wyeth Tricyclic pyridyl carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists
US7109193B2 (en) 2001-04-12 2006-09-19 Wyeth Tricyclic diazepines tocolytic oxytocin receptor antagonists
US7202239B2 (en) 2001-04-12 2007-04-10 Wyeth Cyclohexylphenyl carboxamides tocolytic oxytocin receptor antagonists
US6900200B2 (en) 2001-04-12 2005-05-31 Wyeth Tricyclic hydroxy carboxamides and derivatives thereof tocolytic oxytocin receptor antagonists
US6977254B2 (en) 2001-04-12 2005-12-20 Wyeth Hydroxy cyclohexenyl phenyl carboxamides tocolytic oxytocin receptor antagonists
ES2232292B1 (es) * 2003-07-30 2006-11-01 Laboratorios Del Dr. Esteve, S.A. Compuestos sulfonamidicos derivados de benzoxazinona, su preparacion y uso como medicamentos.
US7504401B2 (en) 2003-08-29 2009-03-17 Locus Pharmaceuticals, Inc. Anti-cancer agents and uses thereof
WO2006137485A1 (ja) * 2005-06-24 2006-12-28 Toyama Chemical Co., Ltd. 新規な含窒素複素環化合物およびその塩
BRPI0720441A2 (pt) * 2006-12-08 2014-01-07 Hoffmann La Roche Indóis que atuam como antagonistas de receptor v1a

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1436395A (en) * 1973-12-13 1976-05-19 Ici Ltd Morpholine derivatives
AT336629B (de) * 1974-12-13 1977-05-10 Ici Ltd Verfahren zur herstellung von neuen morpholinderivaten, deren optischen enantiomeren sowie saureaddtionssalzen
FI95572C (fi) * 1987-06-22 1996-02-26 Eisai Co Ltd Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
DE69009785T2 (de) * 1989-02-10 1994-11-03 Otsuka Pharma Co Ltd Carbostyrilderivate.

Also Published As

Publication number Publication date
CN1058779A (zh) 1992-02-19
JP3165867B2 (ja) 2001-05-14
US5300513A (en) 1994-04-05
CN1036651C (zh) 1997-12-10
TW199153B (de) 1993-02-01
EP0470514A1 (de) 1992-02-12
EP0470514B1 (de) 1997-02-19
DK0470514T3 (da) 1997-03-17
ES2100187T3 (es) 1997-06-16
JPH054984A (ja) 1993-01-14
DE69124721T2 (de) 1997-07-17
KR960001722B1 (ko) 1996-02-03
KR930004292A (ko) 1993-03-22
AU8157491A (en) 1992-03-05
AU638346B2 (en) 1993-06-24

Similar Documents

Publication Publication Date Title
DE69124721T2 (de) Carbostyrilderivate und diese enthaltende pharmazeutische Zusammensetzungen
DE69014351D1 (de) Pyridincarbonsäureamid-Derivate und diese enthaltende pharmazeutische Zusammensetzungen.
DE69233474D1 (de) Pharmazeutische Zusammensetzung enthaltend S-Nitrosoimmunoglobuline und Verwendung davon
DE69015842T2 (de) Nicotinsäurederivate und diese enthaltende pharmazeutische Zusammensetzungen.
DE69618587T2 (de) Chinazoline und pharmazeutische zusammensetzungen
ATA129892A (de) Pharmazeutische zusammensetzung
DE3486441T2 (de) 3-Hydroxypyrid-4-one und pharmazeutische Zusammensetzungen
DE69328492D1 (de) Fettsäure-derivate und diese enthaltende pharmazeutische präparationen
DE69320242T2 (de) Medizinische Selbstklebefolie und Arzneimittelzubereitung
BR9200058A (pt) Composto e composicao farmaceutica
DE69732649D1 (de) Heteroarylsulfonamidderivate und diese enthaltende pharmazeutische zubereitungen
DE59108481D1 (de) Stoffgemische und Zusammensetzungen enthaltend Phenothiazine
FI951789A (fi) Uusia taksaanijohdannaisia, niiden valmistus ja niitä sisältävät farmaseuttiset koostumukset
DE3583765D1 (de) Hydantoinderivate und diese enthaltende pharmazeutische zusammensetzungen.
DE69024843T2 (de) Rhodanin-Derivate und pharmazeutische Zusammensetzungen
DE4294862T1 (de) Pharmazeutische Komposition
IL98863A0 (en) Carbostyril derivatives,their preparation and pharmaceutical compositions containing them
DE69323568D1 (de) Antimikrobielle Zusammensetzungen und pharmazeutische Präparate hiervon
DE69415570T2 (de) Esculetin Derivate und pharmazeutische Zusammenstellung
DE69223835T2 (de) Neue Aminophenolderivate und diese enthaltende pharmazeutische Zusammensetzungen
KR900012897A (ko) 구아니딘 유도체 및 이를 함유하는 약제학적 조성물
ATE205204T1 (de) Benzopyrane und diese enthaltende pharmazeutische zusammenstellungen
DE68909555D1 (de) Pyridylketoximether-verbindung und diese enthaltende pharmazeutische zusammensetzung.
DE69907735D1 (de) Melatoninderivate und diese enthaltende pharmazeutische zubereitung
DE69725166D1 (de) Substituierte benzamidderivate und diese enthaltende pharmazeutische zusammensetzung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition