DE69106376T2 - Verfahren zum verbinden von nukleosiden mit einer siloxanbrücke. - Google Patents

Verfahren zum verbinden von nukleosiden mit einer siloxanbrücke.

Info

Publication number
DE69106376T2
DE69106376T2 DE69106376T DE69106376T DE69106376T2 DE 69106376 T2 DE69106376 T2 DE 69106376T2 DE 69106376 T DE69106376 T DE 69106376T DE 69106376 T DE69106376 T DE 69106376T DE 69106376 T2 DE69106376 T2 DE 69106376T2
Authority
DE
Germany
Prior art keywords
nucleoside
nucleosides
silylated
oligonucleotide analog
disclosed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69106376T
Other languages
English (en)
Other versions
DE69106376D1 (de
Inventor
Alexander Ludvik Weis
Ashis Kumar Saha
Frederick Herman Hausheer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sterling Winthrop Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterling Winthrop Inc filed Critical Sterling Winthrop Inc
Application granted granted Critical
Publication of DE69106376D1 publication Critical patent/DE69106376D1/de
Publication of DE69106376T2 publication Critical patent/DE69106376T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon, or a metal, e.g. chelates, vitamin B12

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
DE69106376T 1990-09-12 1991-09-05 Verfahren zum verbinden von nukleosiden mit einer siloxanbrücke. Expired - Fee Related DE69106376T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/581,502 US5214134A (en) 1990-09-12 1990-09-12 Process of linking nucleosides with a siloxane bridge
PCT/US1991/006290 WO1992004364A1 (en) 1990-09-12 1991-09-05 A method of linking nucleosides with a siloxane bridge

Publications (2)

Publication Number Publication Date
DE69106376D1 DE69106376D1 (de) 1995-02-09
DE69106376T2 true DE69106376T2 (de) 1995-07-13

Family

ID=24325456

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69106376T Expired - Fee Related DE69106376T2 (de) 1990-09-12 1991-09-05 Verfahren zum verbinden von nukleosiden mit einer siloxanbrücke.

Country Status (24)

Country Link
US (1) US5214134A (de)
EP (1) EP0548189B1 (de)
JP (1) JPH06506910A (de)
KR (1) KR0173997B1 (de)
AT (1) ATE116328T1 (de)
AU (1) AU651289B2 (de)
BR (1) BR9106838A (de)
CA (1) CA2091559A1 (de)
DE (1) DE69106376T2 (de)
DK (1) DK0548189T3 (de)
ES (1) ES2067246T3 (de)
FI (1) FI931068A (de)
GR (1) GR3015501T3 (de)
HU (1) HUT64555A (de)
IE (1) IE74706B1 (de)
IL (1) IL99451A (de)
MX (1) MX9101039A (de)
MY (1) MY108078A (de)
NO (1) NO930896L (de)
NZ (1) NZ239544A (de)
PT (1) PT98931B (de)
RU (1) RU2079508C1 (de)
TW (1) TW215440B (de)
WO (1) WO1992004364A1 (de)

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NO930896L (no) 1993-06-30
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GR3015501T3 (en) 1995-06-30
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EP0548189A1 (de) 1993-06-30
IE913213A1 (en) 1992-02-25
EP0548189B1 (de) 1994-12-28
HUT64555A (en) 1994-01-28
NO930896D0 (no) 1993-03-11
IE74706B1 (en) 1997-07-30
KR0173997B1 (en) 1999-02-01
RU2079508C1 (ru) 1997-05-20
AU8533991A (en) 1992-03-30
BR9106838A (pt) 1993-08-24
AU651289B2 (en) 1994-07-14
KR930702375A (ko) 1993-09-08
IL99451A (en) 1995-12-31
DE69106376D1 (de) 1995-02-09
US5214134A (en) 1993-05-25
ES2067246T3 (es) 1995-03-16
WO1992004364A1 (en) 1992-03-19
PT98931A (pt) 1992-07-31
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FI931068A (fi) 1993-04-06
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PT98931B (pt) 1999-01-29
HU9300692D0 (en) 1993-11-29

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