DE69102928D1 - Einrichtung zur Verabreichung pulverisierter medizinischer Substanzen. - Google Patents

Einrichtung zur Verabreichung pulverisierter medizinischer Substanzen.

Info

Publication number
DE69102928D1
DE69102928D1 DE69102928T DE69102928T DE69102928D1 DE 69102928 D1 DE69102928 D1 DE 69102928D1 DE 69102928 T DE69102928 T DE 69102928T DE 69102928 T DE69102928 T DE 69102928T DE 69102928 D1 DE69102928 D1 DE 69102928D1
Authority
DE
Germany
Prior art keywords
nozzle
chamber
dose
cavity
central channel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69102928T
Other languages
English (en)
Other versions
DE69102928T2 (de
Inventor
Paolo Chiesi
Paolo Ventura
Isabella Panza
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Chiesi Farmaceutici SpA
Original Assignee
Chiesi Farmaceutici SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11163212&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69102928(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Chiesi Farmaceutici SpA filed Critical Chiesi Farmaceutici SpA
Publication of DE69102928D1 publication Critical patent/DE69102928D1/de
Application granted granted Critical
Publication of DE69102928T2 publication Critical patent/DE69102928T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
    • A61M11/001—Particle size control
    • A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0066—Inhalators with dosage or measuring devices with means for varying the dose size
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Medical Informatics (AREA)
  • Medicinal Preparation (AREA)
  • External Artificial Organs (AREA)
  • Nozzles (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Paper (AREA)
  • Earth Drilling (AREA)
  • Glass Compositions (AREA)
  • Saccharide Compounds (AREA)
DE69102928T 1990-04-12 1991-04-08 Einrichtung zur Verabreichung pulverisierter medizinischer Substanzen. Expired - Lifetime DE69102928T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20025A IT1240750B (it) 1990-04-12 1990-04-12 Dispositivo per la somministrazione di sostanze medicamentose in polvere

Publications (2)

Publication Number Publication Date
DE69102928D1 true DE69102928D1 (de) 1994-08-25
DE69102928T2 DE69102928T2 (de) 1994-11-03

Family

ID=11163212

Family Applications (2)

Application Number Title Priority Date Filing Date
DE199191105491T Pending DE451745T1 (de) 1990-04-12 1991-04-08 Einrichtung zur verabreichung pulverisierter medizinischer substanzen.
DE69102928T Expired - Lifetime DE69102928T2 (de) 1990-04-12 1991-04-08 Einrichtung zur Verabreichung pulverisierter medizinischer Substanzen.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE199191105491T Pending DE451745T1 (de) 1990-04-12 1991-04-08 Einrichtung zur verabreichung pulverisierter medizinischer substanzen.

Country Status (22)

Country Link
US (1) US5351683A (de)
EP (1) EP0451745B1 (de)
JP (1) JP3209539B2 (de)
KR (1) KR0159044B1 (de)
AT (1) ATE108676T1 (de)
AU (1) AU640764B2 (de)
CA (1) CA2040269A1 (de)
DE (2) DE451745T1 (de)
DK (1) DK0451745T3 (de)
EG (1) EG19770A (de)
ES (1) ES2026835T3 (de)
FI (1) FI103952B1 (de)
GR (1) GR910300136T1 (de)
HK (1) HK1006683A1 (de)
HU (1) HU209475B (de)
IE (1) IE66035B1 (de)
IT (1) IT1240750B (de)
MY (1) MY105476A (de)
NO (1) NO300760B1 (de)
NZ (1) NZ237763A (de)
PT (1) PT97326B (de)
ZA (1) ZA912711B (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD469527S1 (en) 1995-12-07 2003-01-28 Jago Research Ag Pharmacological inhaler

Families Citing this family (70)

* Cited by examiner, † Cited by third party
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KR960002186B1 (ko) * 1991-04-15 1996-02-13 레이라스 오와이 분말상 약품의 1회 복용량 측정장치
US5492112A (en) * 1991-05-20 1996-02-20 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5469843A (en) * 1991-11-12 1995-11-28 Minnesota Mining And Manufacturing Company Inhalation device
DE59303719D1 (de) * 1992-06-05 1996-10-17 Hoechst Ag Inhalator
AU683036B2 (en) * 1992-12-18 1997-10-30 Merck Sharp & Dohme Corp. Inhaler for powdered medications
HU216405B (hu) * 1993-03-03 1999-06-28 Tenax Corp. Hordozóelem por alakú gyógyszerek adagolására szolgáló inhalálókészülékhez
US5388572A (en) * 1993-10-26 1995-02-14 Tenax Corporation (A Connecticut Corp.) Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
US5388573A (en) * 1993-12-02 1995-02-14 Tenax Corporation Dry powder inhalator medicament carrier
GB9326574D0 (en) * 1993-12-31 1994-03-02 King S College London Dry power inhalers
DE4440734A1 (de) * 1994-11-15 1996-05-23 Bayer Ag Abscheidesystem für einen Pulverinhalator
US5622163A (en) 1994-11-29 1997-04-22 Iep Group, Inc. Counter for fluid dispensers
US5901703A (en) * 1995-02-06 1999-05-11 Unisia Jecs Corporation Medicine administering device for nasal cavities
JP3434396B2 (ja) * 1995-06-30 2003-08-04 株式会社日立ユニシアオートモティブ 鼻腔用投薬器
US5669378A (en) * 1995-12-21 1997-09-23 Pera; Ivo Inhaling device
CN1159076C (zh) 1996-02-21 2004-07-28 先灵公司 粉状药物吸入器
SE9700948D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler X
SE9700943D0 (sv) * 1997-03-14 1997-03-14 Astra Ab Powder inhaler V
JP3488620B2 (ja) * 1998-02-05 2004-01-19 株式会社日立ユニシアオートモティブ 吸入式投薬器
US6488648B1 (en) * 1999-01-14 2002-12-03 Teijin Limited Device for feeding a powder in a predetermined amount and method thereof
US6116234A (en) * 1999-02-01 2000-09-12 Iep Pharmaceutical Devices Inc. Metered dose inhaler agitator
DE29908593U1 (de) 1999-05-14 1999-07-22 Jago Research AG, Hergiswil Mundstück für einen Inhalator zur Abgabe eines Medikaments
JP4540906B2 (ja) 1999-06-05 2010-09-08 イノバータ・バイオメッド・リミテッド 放出システム
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
GB9920839D0 (en) 1999-09-04 1999-11-10 Innovata Biomed Ltd Inhaler
CA2393428A1 (en) * 1999-12-07 2001-06-14 Kari Seppala Multidose powder inhaler
MXPA02008403A (es) 2000-02-28 2004-09-27 Vectura Ltd Mejoras en o relacionadas con el suministro de farmacos por via oral.
GB2367756B (en) * 2000-10-12 2003-01-08 Bespak Plc Dispensing apparatus
SE0101825D0 (sv) * 2001-05-22 2001-05-22 Astrazeneca Ab An Inhalation device
GB0128148D0 (en) 2001-11-23 2002-01-16 Innovata Biomed Ltd Assembly
CA2479751C (en) * 2002-03-20 2008-06-03 Trent Poole Inhalation apparatus
BRPI0509348A (pt) 2004-04-21 2007-09-11 Innovata Biomed Ltd inalador
GB0409197D0 (en) 2004-04-24 2004-05-26 Innovata Biomed Ltd Device
US7448385B2 (en) * 2004-06-07 2008-11-11 Purepharm Inc. Nasal adaptation of an oral inhaler device
KR101273120B1 (ko) 2004-08-20 2013-06-13 맨카인드 코포레이션 다이케토피페라진 합성의 촉매 작용
KR101644250B1 (ko) 2004-08-23 2016-07-29 맨카인드 코포레이션 약물 전달용 디케토피페라진염, 디케토모르포린염 또는 디케토디옥산염
US8210171B2 (en) 2004-09-13 2012-07-03 Oriel Therapeutics, Inc. Tubular dry powder drug containment systems, associated inhalers and methods
KR101486397B1 (ko) 2005-09-14 2015-01-28 맨카인드 코포레이션 활성제에 대한 결정질 미립자 표면의 친화력의 증가를 기반으로 하는 약물 제제화의 방법
US20070101991A1 (en) * 2005-11-08 2007-05-10 Mederio Ag Optimizing release of dry medicament powder
WO2007095109A2 (en) * 2006-02-10 2007-08-23 Tobac, Inc. Nasal tobacco inhaler
BRPI0707991B8 (pt) 2006-02-22 2021-05-25 Mannkind Corp métodos de preparação de um medicamento em pó seco com uma propriedade farmacêutica melhorada, dito pó seco e uso de uma quantidade efetiva do pó seco
DE102006047667B3 (de) * 2006-09-28 2008-04-24 Ing. Erich Pfeiffer Gmbh Inhalationsvorrichtung
WO2009046215A2 (en) * 2007-10-02 2009-04-09 Lab International Srl Safety and abuse deterrent improved device
EP2058025B1 (de) * 2007-11-09 2014-09-03 Hitachi Ltd. Vorrichtung zur Verabreichung von Pulvermedikation
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
CN104491962B (zh) 2008-06-13 2018-10-23 曼金德公司 干粉吸入器和用于药物输送的***
ES2421385T3 (es) 2008-06-20 2013-09-02 Mannkind Corp Aparato interactivo y procedimiento para establecer el perfil, en tiempo real, de esfuerzos de inhalación
TWI494123B (zh) 2008-08-11 2015-08-01 Mannkind Corp 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
WO2010135340A2 (en) 2009-05-18 2010-11-25 3M Innovative Properties Company Dry powder inhalers
US8734845B2 (en) 2009-06-12 2014-05-27 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
US9016147B2 (en) 2009-11-03 2015-04-28 Mannkind Corporation Apparatus and method for simulating inhalation efforts
EP2582421A1 (de) 2010-06-21 2013-04-24 MannKind Corporation System und verfahren zur verabreichung von arzneimitteln in trockenpulverform
SG10201606220QA (en) 2011-04-01 2016-09-29 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
KR20140095483A (ko) 2011-10-24 2014-08-01 맨카인드 코포레이션 통증을 치료하기 위한 방법 및 조성물
EP2809780B1 (de) 2012-02-01 2018-05-02 Protalix Ltd. Inhalierbare flüssige formulierungen der dnase i
JP6312262B2 (ja) 2012-07-12 2018-04-18 マンカインド コーポレイション 乾燥粉末薬物送達システム
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
SG11201507564PA (en) 2013-03-15 2015-10-29 Mannkind Corp Microcrystalline diketopiperazine compositions and methods
AU2014290438B2 (en) 2013-07-18 2019-11-07 Mannkind Corporation Heat-stable dry powder pharmaceutical compositions and methods
US11446127B2 (en) 2013-08-05 2022-09-20 Mannkind Corporation Insufflation apparatus and methods
WO2015148905A1 (en) 2014-03-28 2015-10-01 Mannkind Corporation Use of ultrarapid acting insulin
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
WO2016057693A1 (en) 2014-10-10 2016-04-14 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide
EP3294390B1 (de) 2015-05-08 2022-10-05 Iconovo AB Trockenpulverinhalator
US10285987B2 (en) 2017-04-28 2019-05-14 Amplipharm Pharmaceuticals, LLC Device and kit for dosing and dispensing non-liquid medicine
IT201900006368A1 (it) * 2019-04-26 2020-10-26 Hsd Holding Smart Device S R L Inalatore di sostanze medicinali
CN114072136A (zh) 2019-04-29 2022-02-18 英斯梅德股份有限公司 曲前列素前药的干粉组合物及其使用方法
WO2023150747A1 (en) 2022-02-07 2023-08-10 Insmed Incorporated Dry powder compositions of bedaquiline and salts and methods of use thereof

Family Cites Families (10)

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US2259759A (en) * 1940-06-15 1941-10-21 Owens Illinois Glass Co Inhaler
US2310681A (en) * 1942-03-04 1943-02-09 Victor Metal Products Corp Inhaler
US2579280A (en) * 1949-06-25 1951-12-18 Macgregor Instr Company Inhaler
US2609817A (en) * 1950-06-08 1952-09-09 Falcone Anthony Inhaler
US4069819A (en) * 1973-04-13 1978-01-24 Societa Farmaceutici S.P.A. Inhalation device
YU41046B (en) * 1974-08-22 1986-10-31 Schering Ag Medicine inholating device
IT7920688V0 (it) * 1979-02-05 1979-02-05 Chiesi Paolo Parma Inalatore per sostanze medicamentose pulverulente, con combinata funzione di dosatore.
US4274403A (en) * 1979-08-29 1981-06-23 Struve Roger L Inhaler
DE3345722A1 (de) * 1983-12-17 1985-06-27 Boehringer Ingelheim KG, 6507 Ingelheim Inhalator
SE466684B (sv) * 1989-03-07 1992-03-23 Draco Ab Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD469527S1 (en) 1995-12-07 2003-01-28 Jago Research Ag Pharmacological inhaler

Also Published As

Publication number Publication date
EG19770A (en) 1996-01-31
FI103952B (fi) 1999-10-29
IT1240750B (it) 1993-12-17
IE911219A1 (en) 1991-10-23
IE66035B1 (en) 1995-11-29
ZA912711B (en) 1992-01-29
EP0451745B1 (de) 1994-07-20
ES2026835T3 (es) 1994-11-01
ATE108676T1 (de) 1994-08-15
PT97326B (pt) 1998-08-31
DK0451745T3 (da) 1994-11-14
FI103952B1 (fi) 1999-10-29
NO911396D0 (no) 1991-04-10
DE69102928T2 (de) 1994-11-03
KR0159044B1 (ko) 1998-11-16
US5351683A (en) 1994-10-04
NZ237763A (en) 1994-03-25
NO911396L (no) 1991-10-14
PT97326A (pt) 1992-01-31
NO300760B1 (no) 1997-07-21
EP0451745A1 (de) 1991-10-16
MY105476A (en) 1994-10-31
FI911738A (fi) 1991-10-13
CA2040269A1 (en) 1991-10-13
HK1006683A1 (en) 1999-03-12
HU911187D0 (en) 1991-10-28
DE451745T1 (de) 1992-02-27
GR910300136T1 (en) 1992-06-30
HUT59840A (en) 1992-07-28
HU209475B (en) 1994-06-28
ES2026835T1 (es) 1992-05-16
IT9020025A1 (it) 1991-10-12
AU7432491A (en) 1991-10-17
FI911738A0 (fi) 1991-04-11
IT9020025A0 (it) 1990-04-12
KR910018047A (ko) 1991-11-30
JPH04227269A (ja) 1992-08-17
AU640764B2 (en) 1993-09-02
JP3209539B2 (ja) 2001-09-17

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Legal Events

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8364 No opposition during term of opposition