DE69033425D1 - HCV-Isolat J-1 - Google Patents
HCV-Isolat J-1Info
- Publication number
- DE69033425D1 DE69033425D1 DE69033425T DE69033425T DE69033425D1 DE 69033425 D1 DE69033425 D1 DE 69033425D1 DE 69033425 T DE69033425 T DE 69033425T DE 69033425 T DE69033425 T DE 69033425T DE 69033425 D1 DE69033425 D1 DE 69033425D1
- Authority
- DE
- Germany
- Prior art keywords
- hcv
- hcv isolate
- new
- isolate
- hcv1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241000711549 Hepacivirus C Species 0.000 abstract 3
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 abstract 1
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000014616 translation Effects 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/24011—Flaviviridae
- C12N2770/24211—Hepacivirus, e.g. hepatitis C virus, hepatitis G virus
- C12N2770/24222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Gastroenterology & Hepatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Laminated Bodies (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US456142 | 1983-01-06 | ||
US40804589A | 1989-09-15 | 1989-09-15 | |
US408045 | 1989-09-15 | ||
US45614289A | 1989-12-21 | 1989-12-21 |
Publications (3)
Publication Number | Publication Date |
---|---|
DE69033425D1 true DE69033425D1 (de) | 2000-02-24 |
DE69033425T2 DE69033425T2 (de) | 2000-06-08 |
DE69033425T3 DE69033425T3 (de) | 2010-02-18 |
Family
ID=27020120
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69033425T Expired - Lifetime DE69033425T3 (de) | 1989-09-15 | 1990-09-17 | HCV-Isolat J-1 |
Country Status (11)
Country | Link |
---|---|
EP (2) | EP0419182B2 (de) |
JP (3) | JP3156200B2 (de) |
AT (1) | ATE188998T1 (de) |
CA (1) | CA2065287C (de) |
DE (1) | DE69033425T3 (de) |
DK (1) | DK0419182T4 (de) |
ES (1) | ES2141081T5 (de) |
GR (1) | GR3033100T3 (de) |
IE (2) | IE903363A1 (de) |
PT (1) | PT95329B (de) |
WO (1) | WO1991004262A1 (de) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7166287B1 (en) | 1989-12-18 | 2007-01-23 | Glaxo Wellcome Inc. | Viral agent |
DE4040339C2 (de) | 1989-12-18 | 1999-07-08 | Wellcome Found | Virales Agens |
US6596476B1 (en) * | 1989-12-22 | 2003-07-22 | Abbott Laboratories | Hepatitis C assay |
DE69133617D1 (de) * | 1990-04-04 | 2009-07-23 | Novartis Vaccines & Diagnostic | Protease von Hepatitis C Virus |
JP3050395B2 (ja) * | 1990-06-12 | 2000-06-12 | 国立感染症研究所長 | C型肝炎ウイルス抗原ポリペプチド、その産生方法および抗体の検出方法 |
US5747339A (en) | 1990-06-25 | 1998-05-05 | Research Foundation For Microbial Diseases Of Osaka | Non-A, non-B hepatitis virus genomic CDNA and antigen polypeptide |
EP0469348B1 (de) * | 1990-07-11 | 1997-03-12 | SHIONOGI SEIYAKU KABUSHIKI KAISHA trading under the name of SHIONOGI & CO. LTD. | cDNS-Sequenz und Detektion des Hepatitis C-Virus |
WO1992001714A1 (en) * | 1990-07-24 | 1992-02-06 | Yamanouchi Pharmaceutical Co., Ltd. | Non-a non-b hepatitis virus antigen |
EP0770679B2 (de) * | 1990-11-03 | 2009-12-30 | Siemens Healthcare Diagnostics Products GmbH | HCV-spezifische Peptide, Mittel dazu und ihre Verwendung |
EP0485209A1 (de) * | 1990-11-08 | 1992-05-13 | Immuno Japan Inc. | Mit Non-A Non-B Hepatitis Virus verwandtes Antigen, Aufspürsysteme für Antikörper, Polynukleotide und Polypeptide |
WO1992009634A1 (en) * | 1990-11-29 | 1992-06-11 | Toray Industries, Incorporated | Non-a non-b hepatitis virus antigen protein |
US5574132A (en) * | 1991-04-05 | 1996-11-12 | Biochem Immunosystems Inc. | Peptides and mixtures thereof for detecting antibodies to hepatitis C virus (HCV) |
CA2065690A1 (en) * | 1991-04-10 | 1992-10-11 | Hiroaki Okamoto | Non-a, non-b hepatitis related antigens, detection systems, polynucleotides and polypeptides |
UA43310C2 (uk) * | 1991-06-10 | 2001-12-17 | Лакі Лімітед | Поліпептид вірусу гепатиту с корейського типу (khcv), кднк khcv, полінуклеотид, що кодує поліпептид khcv, рекомбінантний експресуючий вектор, клітина, трансформована вектором, поліпептид, який містить епітоп, спосіб одержання поліпептиду, діагностичний засіб для визначення антитіла, спрямованого проти антигену khcv, діагностичний набір, діагностичний спосіб визначення антитіла, спрямованого проти антигену khcv, моноклональне антитіло, клітинна лінія, діагностичний засіб для визначення епітопу khcv у зразку, що піддають тестуванню, спосіб визначення епітопу khcv, вакцина для лікування або профілактики інфекції khcv (варіанти), набір для визначення полінуклеотиду khcv, спосіб визначення полінуклеотиду з khcv |
UA40572C2 (uk) * | 1991-06-24 | 2001-08-15 | Чірон Корпорейшн | Поліпептид, що містить укорочену послідовність вірусу гепатиту с, ізольований епітоп, реагент для імуноаналізу на вірус гепатиту с (варіанти), спосіб виявлення наявності антитіл (варіанти) |
DE69223562T2 (de) * | 1991-08-27 | 1998-06-04 | Hoffmann La Roche | Verfahren und Reagenzien zum Nachweis von Hepatitis C |
ATE228564T1 (de) * | 1991-09-13 | 2002-12-15 | Chiron Corp | Zusammensetzung aus mehreren immunreaktiven hepatitis-c-virus-polypeptiden |
CA2119013A1 (en) * | 1991-09-16 | 1993-04-01 | Richard R. Lesniewski | Hepatitis c assay |
US6709828B1 (en) | 1992-03-06 | 2004-03-23 | N.V. Innogenetics S.A. | Process for the determination of peptides corresponding to immunologically important epitopes and their use in a process for determination of antibodies or biotinylated peptides corresponding to immunologically important epitopes, a process for preparing them and compositions containing them |
US6667387B1 (en) | 1996-09-30 | 2003-12-23 | N.V. Innogenetics S.A. | HCV core peptides |
US6620414B2 (en) | 1992-03-27 | 2003-09-16 | Smithkline Beecham Biologicals (S.A.) | Hepatitis vaccines containing 3-0-deacylated monophoshoryl lipid A |
MY111880A (en) * | 1992-03-27 | 2001-02-28 | Smithkline Beecham Biologicals S A | Hepatitis vaccines containing 3-0 deacylated monophosphoryl lipid a |
US6174868B1 (en) | 1992-09-10 | 2001-01-16 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of hepatitis C virus-associated diseases |
US6391542B1 (en) | 1992-09-10 | 2002-05-21 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of Hepatitis C virus-associated diseases |
US6995146B2 (en) | 1992-09-10 | 2006-02-07 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of hepatitis C virus-associated diseases |
US6433159B1 (en) | 1992-09-10 | 2002-08-13 | Isis Pharmaceuticals, Inc. | Compositions and methods for treatment of Hepatitis C virus associated diseases |
ATE553201T1 (de) | 1993-04-27 | 2012-04-15 | Innogenetics Nv | Hepatitis c virus genotypsequenzen sowie ihre verwendung als behandlungs- und nachweismittel |
US7255997B1 (en) | 1993-04-27 | 2007-08-14 | N.V. Innogenetics S.A. | Sequences of hepatitis C virus genotypes and their use as therapeutic and diagnostic agents |
DK0804584T3 (da) | 1994-10-21 | 2002-09-23 | Innogenetics Nv | Sekvenser af hepatitis C virus genotype 7 og deres anvendelse som profylaktiske, terapeutiske og diagnostiske midler |
EP1178116A1 (de) * | 2000-08-03 | 2002-02-06 | Hybrigenics S.A. | Sid nukleische Saüre und aus einem pathogenischen Stamm des Hepatitis C Viruses selektierte Polypeptide und deren Verwendungenthereof |
AU2001290178A1 (en) * | 2000-08-17 | 2002-02-25 | Tripep Ab | A hepatitis c virus non-structural ns3/4a fusion gene |
US7022830B2 (en) | 2000-08-17 | 2006-04-04 | Tripep Ab | Hepatitis C virus codon optimized non-structural NS3/4A fusion gene |
JP2002125688A (ja) * | 2000-10-30 | 2002-05-08 | Tosoh Corp | C型肝炎ウイルスの高感度検出のためのオリゴヌクレオチドおよび検出法 |
DE10112748A1 (de) * | 2001-03-14 | 2002-09-19 | Transmit Technologietransfer | Erfindung betreffend HCV-Erkrankungen |
US7196183B2 (en) | 2001-08-31 | 2007-03-27 | Innogenetics N.V. | Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent |
US7378234B2 (en) * | 2002-09-13 | 2008-05-27 | Intercell Ag | Method for isolating hepatitis C virus peptides |
ES2596753T3 (es) | 2003-08-29 | 2017-01-11 | Fujirebio Europe N.V. | Nuevo clado del virus de la hepatitis C y secuencias prototipo del mismo |
JP5138230B2 (ja) | 2004-01-07 | 2013-02-06 | サード・ウェーブ・テクノロジーズ・インク | C型肝炎ウイルスの遺伝子型の決定方法 |
CN105697424B (zh) * | 2016-01-19 | 2019-01-08 | 江苏大学 | 一种泵站用防旋涡装置 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2480779B2 (fr) * | 1979-08-30 | 1986-07-18 | Anvar | Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur |
US4870026A (en) * | 1982-09-16 | 1989-09-26 | The General Hospital Corporation | Non-A, non-B. hepatitis, virus, methods of identification purification, characterization, diagnosis and immunization |
US4673634A (en) * | 1985-03-08 | 1987-06-16 | The United States Of America As Represented By The Department Of Health And Human Services | Purified antigen from non-A, non-B hepatitis causing factor |
US4683195A (en) | 1986-01-30 | 1987-07-28 | Cetus Corporation | Process for amplifying, detecting, and/or-cloning nucleic acid sequences |
US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
US4868105A (en) | 1985-12-11 | 1989-09-19 | Chiron Corporation | Solution phase nucleic acid sandwich assay |
US5032511A (en) * | 1987-03-31 | 1991-07-16 | Mitsubishi Kasei Corporation | DNA fragments coding for antigens specific to non-A non-B hepatitis, expression vectors containing said DNA fragments, transformants and process for producing said antigens |
JP2590885B2 (ja) * | 1987-03-31 | 1997-03-12 | 三菱化学株式会社 | Dna断片 |
JPH01124387A (ja) * | 1987-11-10 | 1989-05-17 | Mitsubishi Kasei Corp | 非a非b型肝炎特異抗原をコードするdnaを有する発現ベクター、形質転換体および該抗原の産生方法 |
CA1339351C (en) | 1987-10-15 | 1997-08-26 | Michael S. Urdea | Nucleic acid multimers and amplified nucleic acid hybridization assays using same |
DE3886363T3 (de) * | 1987-11-18 | 2004-09-09 | Chiron Corp. (N.D.Ges.D. Staates Delaware), Emeryville | NANBV-Diagnostika |
JP2500880Y2 (ja) * | 1988-05-02 | 1996-06-12 | カシオ計算機株式会社 | 液晶表示装置 |
HU225068B1 (en) * | 1989-03-17 | 2006-05-29 | Chiron Corp | Process for producing diagnostics and vaccine of nanbh |
JPH0330676A (ja) * | 1989-06-28 | 1991-02-08 | Sanwa Kagaku Kenkyusho Co Ltd | 非a非b型肝炎ウイルスのdna、そのクローン及びこれらの調製法 |
EP0416725A3 (en) * | 1989-07-14 | 1991-03-20 | Chugai Seiyaku Kabushiki Kaisha | Blood-borne non-a, non-b hepatitis specific protein, dna encoding it, and process for its production |
-
1990
- 1990-09-14 JP JP51318890A patent/JP3156200B2/ja not_active Expired - Fee Related
- 1990-09-14 CA CA002065287A patent/CA2065287C/en not_active Expired - Lifetime
- 1990-09-14 WO PCT/US1990/005242 patent/WO1991004262A1/en active Application Filing
- 1990-09-17 ES ES90310149T patent/ES2141081T5/es not_active Expired - Lifetime
- 1990-09-17 PT PT95329A patent/PT95329B/pt not_active IP Right Cessation
- 1990-09-17 DK DK90310149T patent/DK0419182T4/da active
- 1990-09-17 AT AT90310149T patent/ATE188998T1/de not_active IP Right Cessation
- 1990-09-17 EP EP90310149A patent/EP0419182B2/de not_active Expired - Lifetime
- 1990-09-17 EP EP99101746A patent/EP0939128A3/de not_active Withdrawn
- 1990-09-17 DE DE69033425T patent/DE69033425T3/de not_active Expired - Lifetime
- 1990-09-17 IE IE336390A patent/IE903363A1/en not_active IP Right Cessation
-
1996
- 1996-10-24 JP JP8282753A patent/JPH09187285A/ja not_active Withdrawn
-
2000
- 2000-03-29 GR GR20000400789T patent/GR3033100T3/el unknown
-
2002
- 2002-02-19 IE IE20020123A patent/IE20020123A1/en not_active Application Discontinuation
-
2005
- 2005-01-26 JP JP2005018955A patent/JP2005143512A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JP2005143512A (ja) | 2005-06-09 |
JPH05506773A (ja) | 1993-10-07 |
GR3033100T3 (en) | 2000-08-31 |
CA2065287C (en) | 1999-12-21 |
EP0939128A2 (de) | 1999-09-01 |
EP0419182B2 (de) | 2009-07-22 |
WO1991004262A1 (en) | 1991-04-04 |
EP0939128A3 (de) | 2004-06-09 |
JP3156200B2 (ja) | 2001-04-16 |
ES2141081T3 (es) | 2000-03-16 |
EP0419182A1 (de) | 1991-03-27 |
PT95329A (pt) | 1991-08-14 |
DK0419182T4 (da) | 2009-11-23 |
DK0419182T3 (da) | 2000-04-17 |
IE20020123A1 (en) | 2003-05-28 |
EP0419182B1 (de) | 2000-01-19 |
JPH09187285A (ja) | 1997-07-22 |
ES2141081T5 (es) | 2009-12-11 |
PT95329B (pt) | 1998-04-30 |
ATE188998T1 (de) | 2000-02-15 |
CA2065287A1 (en) | 1991-03-16 |
DE69033425T3 (de) | 2010-02-18 |
DE69033425T2 (de) | 2000-06-08 |
IE903363A1 (en) | 1991-04-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE188998T1 (de) | Hcv-isolat j-1 | |
DK0484787T3 (da) | HCV-specifikke peptider, fremgangsmåde til opnåelse deraf og anvendelse deraf | |
DK0644202T3 (da) | Syntetiske antigener til påvisning af antistoffer imod hepatitis C virus | |
DK11789D0 (da) | Rekombinante vaccinia-vira | |
ATE309367T1 (de) | Nukleotid- und aminosäuresequenzen der gene des hüllproteins 1 und des kernproteins von hepatitis c virus | |
ATE119545T1 (de) | Felincalicivirus-capsid-protein und nukleotidsequenz. | |
ATE122055T1 (de) | Dna- und rna-moleküle des westlichen subtyps des fsme-virus, polypeptide, die von diesen molekülen codiert werden, und deren verwendung. | |
DE69012989D1 (de) | Peptiden von retinblastoma gen produkten und antikoerper dagegen. | |
FI981381A (fi) | Menetelmä HCV-polypeptidien valmistamiseksi | |
SG145521A1 (en) | Synthetic antigens for the detection of antibodies to hepatitis c virus |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
8363 | Opposition against the patent | ||
8366 | Restricted maintained after opposition proceedings | ||
8327 | Change in the person/name/address of the patent owner |
Owner name: OYA, AKIRA, DR., DIRECTOR GENERAL OF THE NATIO, JP Owner name: NOVARTIS VACCINES AND DIAGNOSTICS, INC., EMERY, US |