DE69020138D1 - Mikroorganismus zur selektiven Herstellung einer spezifischen Komponente von Avermectin und Verfahren zu deren selektiven Herstellung. - Google Patents
Mikroorganismus zur selektiven Herstellung einer spezifischen Komponente von Avermectin und Verfahren zu deren selektiven Herstellung.Info
- Publication number
- DE69020138D1 DE69020138D1 DE69020138T DE69020138T DE69020138D1 DE 69020138 D1 DE69020138 D1 DE 69020138D1 DE 69020138 T DE69020138 T DE 69020138T DE 69020138 T DE69020138 T DE 69020138T DE 69020138 D1 DE69020138 D1 DE 69020138D1
- Authority
- DE
- Germany
- Prior art keywords
- avermectin
- selective production
- microorganism
- specific component
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
- C12N15/03—Bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
- C12P19/623—Avermectin; Milbemycin; Ivermectin; C-076
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Virology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2053411A JP2888586B2 (ja) | 1990-03-05 | 1990-03-05 | エバーメクチンの特定成分を選択生産するための微生物およびその選択的製造法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69020138D1 true DE69020138D1 (de) | 1995-07-20 |
DE69020138T2 DE69020138T2 (de) | 1995-12-14 |
Family
ID=12942087
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69020138T Expired - Fee Related DE69020138T2 (de) | 1990-03-05 | 1990-08-10 | Mikroorganismus zur selektiven Herstellung einer spezifischen Komponente von Avermectin und Verfahren zu deren selektiven Herstellung. |
Country Status (10)
Country | Link |
---|---|
US (2) | US5206155A (de) |
EP (1) | EP0445460B1 (de) |
JP (1) | JP2888586B2 (de) |
AT (1) | ATE123805T1 (de) |
AU (1) | AU629966B2 (de) |
CA (1) | CA2023114C (de) |
DE (1) | DE69020138T2 (de) |
DK (1) | DK0445460T3 (de) |
ES (1) | ES2075881T3 (de) |
NZ (1) | NZ234741A (de) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6103504A (en) * | 1992-03-25 | 2000-08-15 | Pfizer Inc. | Process for production of avermectins and cultures therefor |
IT1255135B (it) * | 1992-05-05 | 1995-10-20 | Principio attivo a base di avermectine, ceppo e procedimento per la sua preparazione e composizione veterinaria che lo contiene. | |
US5292647A (en) * | 1992-11-30 | 1994-03-08 | Eli Lilly And Company | Strain of streptomyces for producing avermectins and processes therewith |
BR9407141A (pt) * | 1993-07-23 | 1996-09-17 | Pfizer | Método para a precipatação de avermectinas naturais |
KR20040099389A (ko) * | 1998-02-13 | 2004-11-26 | 화이자 프로덕츠 인코포레이티드 | 스트렙토마이세스 하이그로스코피쿠스 유전자 |
CN1202116C (zh) | 1999-02-09 | 2005-05-18 | 社团法人北里研究所 | 除虫菌素衍生物 |
JP2000245457A (ja) | 1999-02-24 | 2000-09-12 | Kitasato Inst:The | エバーメクチンアグリコン合成酵素遺伝子 |
AU2001278694A1 (en) | 2000-08-09 | 2002-02-18 | The Kitasato Institute | Avermectin derivatives |
AU2001277712A1 (en) | 2000-08-09 | 2002-02-18 | The Kitasato Institute | Avermectin derivatives |
CN101429536B (zh) * | 2008-12-15 | 2011-09-14 | 浙江升华拜克生物股份有限公司 | 一种采用全孢子接种工艺生产阿维菌素的方法 |
JP6346673B2 (ja) | 2014-03-10 | 2018-06-20 | 浙江海正薬業股▲ふん▼有限公司Zhejiang Hisun Pharmaceutical CO.,LTD. | アベルメクチン類似体を発現する組換え微生物およびその用途 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE434277B (sv) * | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
US4429042A (en) * | 1978-09-08 | 1984-01-31 | Merck & Co., Inc. | Strain of Streptomyces for producing antiparasitic compounds |
IN167980B (de) * | 1987-01-23 | 1991-01-19 | Pfizer | |
DE3881147T2 (de) * | 1987-10-23 | 1993-09-02 | Pfizer | Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen. |
-
1990
- 1990-03-05 JP JP2053411A patent/JP2888586B2/ja not_active Expired - Fee Related
- 1990-08-01 NZ NZ234741A patent/NZ234741A/en unknown
- 1990-08-06 AU AU60201/90A patent/AU629966B2/en not_active Ceased
- 1990-08-10 ES ES90308842T patent/ES2075881T3/es not_active Expired - Lifetime
- 1990-08-10 DK DK90308842.5T patent/DK0445460T3/da active
- 1990-08-10 EP EP90308842A patent/EP0445460B1/de not_active Expired - Lifetime
- 1990-08-10 AT AT90308842T patent/ATE123805T1/de not_active IP Right Cessation
- 1990-08-10 DE DE69020138T patent/DE69020138T2/de not_active Expired - Fee Related
- 1990-08-10 CA CA002023114A patent/CA2023114C/en not_active Expired - Fee Related
- 1990-08-10 US US07/565,448 patent/US5206155A/en not_active Expired - Lifetime
-
1992
- 1992-12-30 US US07/998,861 patent/US5369021A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
JPH03254678A (ja) | 1991-11-13 |
DK0445460T3 (da) | 1995-08-14 |
EP0445460A1 (de) | 1991-09-11 |
CA2023114A1 (en) | 1991-09-06 |
ATE123805T1 (de) | 1995-06-15 |
AU6020190A (en) | 1991-09-05 |
CA2023114C (en) | 1996-12-17 |
DE69020138T2 (de) | 1995-12-14 |
NZ234741A (en) | 1992-03-26 |
US5206155A (en) | 1993-04-27 |
EP0445460B1 (de) | 1995-06-14 |
US5369021A (en) | 1994-11-29 |
AU629966B2 (en) | 1992-10-15 |
JP2888586B2 (ja) | 1999-05-10 |
ES2075881T3 (es) | 1995-10-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |