DE69015541D1 - Chinolinderivate, deren Herstellung und Verwendung. - Google Patents
Chinolinderivate, deren Herstellung und Verwendung.Info
- Publication number
- DE69015541D1 DE69015541D1 DE69015541T DE69015541T DE69015541D1 DE 69015541 D1 DE69015541 D1 DE 69015541D1 DE 69015541 T DE69015541 T DE 69015541T DE 69015541 T DE69015541 T DE 69015541T DE 69015541 D1 DE69015541 D1 DE 69015541D1
- Authority
- DE
- Germany
- Prior art keywords
- chem
- production
- quinoline derivatives
- alkyl group
- lower alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Measurement Of Radiation (AREA)
- Quinoline Compounds (AREA)
- Holo Graphy (AREA)
- Detergent Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP26278289 | 1989-10-06 | ||
JP32229089 | 1989-12-11 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69015541D1 true DE69015541D1 (de) | 1995-02-09 |
DE69015541T2 DE69015541T2 (de) | 1995-06-01 |
Family
ID=26545706
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69015541T Expired - Fee Related DE69015541T2 (de) | 1989-10-06 | 1990-10-05 | Chinolinderivate, deren Herstellung und Verwendung. |
Country Status (17)
Country | Link |
---|---|
US (1) | US5223513A (de) |
EP (1) | EP0421456B1 (de) |
KR (1) | KR910007883A (de) |
CN (1) | CN1050715A (de) |
AT (1) | ATE116301T1 (de) |
AU (1) | AU629048B2 (de) |
CA (1) | CA2026890C (de) |
DE (1) | DE69015541T2 (de) |
FI (1) | FI904915A0 (de) |
HU (1) | HUT55364A (de) |
IE (1) | IE903454A1 (de) |
IL (1) | IL95839A (de) |
NO (1) | NO904300L (de) |
NZ (1) | NZ235582A (de) |
PT (1) | PT95515A (de) |
RU (1) | RU2001910C1 (de) |
TW (1) | TW205037B (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH03181465A (ja) * | 1989-12-11 | 1991-08-07 | Takeda Chem Ind Ltd | キノリン誘導体 |
JPH0776215B2 (ja) * | 1991-04-26 | 1995-08-16 | フアイザー・インコーポレイテツド | 4−アリール−3−(ヘテロアリールウレイド)キノリン誘導体 |
ES2125325T3 (es) * | 1992-01-23 | 1999-03-01 | Pfizer | Derivados de 4-fenil-3-(heteroarilureido)-1,2-dihidro-2-oxoquinolina como agentes antihipercolesterolemicos y antiateroscleroticos. |
TW241258B (de) * | 1992-04-15 | 1995-02-21 | Takeda Pharm Industry Co Ltd | |
CA2134359C (en) * | 1992-05-28 | 1997-07-01 | Ernest S. Hamanaka | New n-aryl and n-heteroarylurea derivatives as inhibitors of acyl coenzyme a: cholesterol acyl transferase (acat) |
NO179904C (no) * | 1992-09-04 | 1997-01-08 | Takeda Chemical Industries Ltd | Kondenserte heterocykliske forbindelser og deres anvendelse |
US5565472A (en) * | 1992-12-21 | 1996-10-15 | Pfizer Inc. | 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents |
NZ264063A (en) * | 1993-08-13 | 1995-11-27 | Nihon Nohyaku Co Ltd | N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions |
TW263498B (de) * | 1993-11-10 | 1995-11-21 | Takeda Pharm Industry Co Ltd | |
US6133326A (en) | 1994-08-31 | 2000-10-17 | Pfizer Inc | Compositions and methods for decreasing sebum production |
US5843957A (en) * | 1995-05-19 | 1998-12-01 | Sumitomo Pharmaceuticals Company, Ltd. | Naphthyridine derivatives |
US5972961A (en) * | 1997-08-28 | 1999-10-26 | Bristol-Myers Squibb Company | 4-aryl-3-aminoquinoline-2-one derivatives as potassium channel modulators |
WO1999043659A1 (fr) | 1998-02-25 | 1999-09-02 | Sumitomo Pharmaceuticals Co., Ltd. | Derives de pyridone et leur procede de fabrication |
US6452008B2 (en) | 1998-02-25 | 2002-09-17 | Sumitomo Pharmaceuticals Company, Limited | Pyridone derivatives and process for preparing the same |
KR20020073574A (ko) * | 2000-02-02 | 2002-09-27 | 워너-램버트 캄파니 | 피지선 장애 치료용 콜레스테롤 에스테르 및 왁스에스테르 합성 이중 억제제 |
CN1234691C (zh) * | 2001-03-02 | 2006-01-04 | 住友化学工业株式会社 | 喹啉-3-羧酸化合物的制备方法 |
CA2539760C (en) * | 2003-09-23 | 2011-01-25 | Merck & Co., Inc. | Quinoline potassium channel inhibitors |
EP2773619B1 (de) * | 2011-11-04 | 2016-11-16 | F.Hoffmann-La Roche Ag | Neue arylchinolinderivate |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1216878B (de) * | 1963-04-02 | 1966-05-18 | Cassella Farbwerke Mainkur Ag | Verfahren zur Herstellung von coronargefaesserweiternden Derivaten des 7-Hydroxy-2-oxo-1, 2-dihydrochinolins |
NO133758C (de) * | 1970-04-04 | 1976-06-23 | Takeda Chemical Industries Ltd | |
JPS555502B1 (de) * | 1971-07-31 | 1980-02-07 | ||
US4530931A (en) * | 1983-01-03 | 1985-07-23 | Usv Pharmaceutical Corp. | 8-Quinoline carbanilates for the inhibition of lipolysis |
EP0166354B1 (de) * | 1984-06-26 | 1992-08-05 | Merck & Co. Inc. | Kondensierte Benzo-Laktam-Verbindungen und deren pharmazeutische Zusammensetzungen |
IE892088L (en) * | 1988-07-12 | 1990-01-12 | William Henry Deryk Morris | Quinoline derivatives, their production and use |
-
1990
- 1990-09-20 TW TW079107912A patent/TW205037B/zh active
- 1990-09-25 IE IE345490A patent/IE903454A1/en unknown
- 1990-09-25 US US07/587,795 patent/US5223513A/en not_active Expired - Fee Related
- 1990-09-28 IL IL9583990A patent/IL95839A/en not_active IP Right Cessation
- 1990-09-28 AU AU63707/90A patent/AU629048B2/en not_active Ceased
- 1990-10-03 NO NO90904300A patent/NO904300L/no unknown
- 1990-10-04 CA CA002026890A patent/CA2026890C/en not_active Expired - Fee Related
- 1990-10-04 PT PT95515A patent/PT95515A/pt not_active Application Discontinuation
- 1990-10-05 FI FI904915A patent/FI904915A0/fi not_active Application Discontinuation
- 1990-10-05 NZ NZ235582A patent/NZ235582A/en unknown
- 1990-10-05 DE DE69015541T patent/DE69015541T2/de not_active Expired - Fee Related
- 1990-10-05 AT AT90119128T patent/ATE116301T1/de not_active IP Right Cessation
- 1990-10-05 HU HU906360A patent/HUT55364A/hu unknown
- 1990-10-05 RU SU904831426A patent/RU2001910C1/ru active
- 1990-10-05 EP EP90119128A patent/EP0421456B1/de not_active Expired - Lifetime
- 1990-10-05 CN CN90108222A patent/CN1050715A/zh active Pending
- 1990-10-06 KR KR1019900015908A patent/KR910007883A/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP0421456B1 (de) | 1994-12-28 |
HUT55364A (en) | 1991-05-28 |
AU629048B2 (en) | 1992-09-24 |
EP0421456A2 (de) | 1991-04-10 |
RU2001910C1 (ru) | 1993-10-30 |
EP0421456A3 (en) | 1991-05-29 |
TW205037B (de) | 1993-05-01 |
DE69015541T2 (de) | 1995-06-01 |
CN1050715A (zh) | 1991-04-17 |
JPH03223254A (ja) | 1991-10-02 |
KR910007883A (ko) | 1991-05-30 |
AU6370790A (en) | 1991-04-11 |
NO904300L (no) | 1991-04-08 |
NZ235582A (en) | 1992-03-26 |
CA2026890A1 (en) | 1991-04-07 |
HU906360D0 (en) | 1991-04-29 |
PT95515A (pt) | 1991-08-14 |
CA2026890C (en) | 2001-09-18 |
US5223513A (en) | 1993-06-29 |
IL95839A0 (en) | 1991-06-30 |
IE903454A1 (en) | 1991-04-10 |
ATE116301T1 (de) | 1995-01-15 |
IL95839A (en) | 1995-03-15 |
FI904915A0 (fi) | 1990-10-05 |
NO904300D0 (no) | 1990-10-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |