DE68920880D1 - 1-amino-5-halogenouracile, verfahren zu deren herstellung und diese enthaltende cns-depressiva. - Google Patents
1-amino-5-halogenouracile, verfahren zu deren herstellung und diese enthaltende cns-depressiva.Info
- Publication number
- DE68920880D1 DE68920880D1 DE68920880T DE68920880T DE68920880D1 DE 68920880 D1 DE68920880 D1 DE 68920880D1 DE 68920880 T DE68920880 T DE 68920880T DE 68920880 T DE68920880 T DE 68920880T DE 68920880 D1 DE68920880 D1 DE 68920880D1
- Authority
- DE
- Germany
- Prior art keywords
- halogenouracile
- depressives
- cns
- amino
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/553—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms with halogen atoms or nitro radicals directly attached to ring carbon atoms, e.g. fluorouracil
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP17834688 | 1988-07-18 | ||
JP17834588 | 1988-07-18 | ||
JP17834788 | 1988-07-18 | ||
PCT/JP1989/000708 WO1990001027A1 (en) | 1988-07-18 | 1989-07-14 | 1-amino-5-halogenouracils, process for their preparation, and central nervous system depressants containing same as active ingredient |
Publications (1)
Publication Number | Publication Date |
---|---|
DE68920880D1 true DE68920880D1 (de) | 1995-03-09 |
Family
ID=27324563
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE68920880T Expired - Lifetime DE68920880D1 (de) | 1988-07-18 | 1989-07-14 | 1-amino-5-halogenouracile, verfahren zu deren herstellung und diese enthaltende cns-depressiva. |
Country Status (5)
Country | Link |
---|---|
US (1) | US5252576A (de) |
EP (1) | EP0425669B1 (de) |
KR (1) | KR900701763A (de) |
DE (1) | DE68920880D1 (de) |
WO (1) | WO1990001027A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2073464A1 (en) * | 1990-01-13 | 1991-07-14 | Masahiro Imaizumi | Anxiolytic drugs |
EP0725317A1 (de) | 1995-01-30 | 1996-08-07 | Agfa-Gevaert N.V. | Verfahren zur Herstellung einer "Polymersuspension" für die Tonerteilchenherstellung |
SG80553A1 (en) * | 1995-07-20 | 2001-05-22 | Tanabe Seiyaku Co | Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract |
US6306909B1 (en) * | 1997-03-12 | 2001-10-23 | Queen's University At Kingston | Anti-epileptogenic agents |
DE10005284A1 (de) * | 2000-02-07 | 2001-08-09 | Bayer Ag | Verfahren zur Herstellung von 1-Amino-3-aryl-uracilen |
IL157845A0 (en) * | 2001-03-13 | 2004-03-28 | Univ Kingston | Anti-epileptogenic agents |
WO2002083651A2 (en) * | 2001-04-11 | 2002-10-24 | Queen's University At Kingston | Pyrimidine compounds as anti-ictogenic and/or anti-epileptogenic agents |
CA2448160A1 (en) * | 2001-05-25 | 2002-12-05 | Queen's University At Kingston | Heterocyclic beta-amino acids and their use as anti-epileptogenic agents |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1561290A (en) * | 1975-10-16 | 1980-02-20 | Nyegaard & Co As | Pyrimid - 2 - ones |
JPS5738774A (en) * | 1980-08-19 | 1982-03-03 | Chugai Pharmaceut Co Ltd | Uracil derivative and its preparation |
US4396623A (en) * | 1981-08-26 | 1983-08-02 | Southern Research Institute | Carbocyclic analogs of uracil nucleosides as antiviral agents |
JPS6293281A (ja) * | 1985-10-17 | 1987-04-28 | Kyowa Hakko Kogyo Co Ltd | 抗腫瘍剤 |
-
1989
- 1989-07-14 EP EP89908257A patent/EP0425669B1/de not_active Expired - Lifetime
- 1989-07-14 DE DE68920880T patent/DE68920880D1/de not_active Expired - Lifetime
- 1989-07-14 WO PCT/JP1989/000708 patent/WO1990001027A1/ja active IP Right Grant
- 1989-07-14 US US07/640,413 patent/US5252576A/en not_active Expired - Fee Related
- 1989-07-14 KR KR1019900700579A patent/KR900701763A/ko not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO1990001027A1 (en) | 1990-02-08 |
EP0425669A1 (de) | 1991-05-08 |
EP0425669A4 (en) | 1991-09-11 |
KR900701763A (ko) | 1990-12-04 |
US5252576A (en) | 1993-10-12 |
EP0425669B1 (de) | 1995-01-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8332 | No legal effect for de |