DE68907718D1 - Verfahren zur pasteurisierung von waessrigen loesungen von faktor viii. - Google Patents

Verfahren zur pasteurisierung von waessrigen loesungen von faktor viii.

Info

Publication number
DE68907718D1
DE68907718D1 DE8989901847T DE68907718T DE68907718D1 DE 68907718 D1 DE68907718 D1 DE 68907718D1 DE 8989901847 T DE8989901847 T DE 8989901847T DE 68907718 T DE68907718 T DE 68907718T DE 68907718 D1 DE68907718 D1 DE 68907718D1
Authority
DE
Germany
Prior art keywords
pasteurizing
aqueous solutions
factor viii
viii
factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989901847T
Other languages
English (en)
Other versions
DE68907718T2 (de
Inventor
Jesper Kihl
Allan Nyrup
Ole Nordfang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of DE68907718D1 publication Critical patent/DE68907718D1/de
Application granted granted Critical
Publication of DE68907718T2 publication Critical patent/DE68907718T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/36—Blood coagulation or fibrinolysis factors
    • A61K38/37—Factors VIII
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0023—Heat
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/04—Heat

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE89901847T 1988-01-15 1989-01-13 Verfahren zur pasteurisierung von wässrigen lösungen von faktor viii. Expired - Fee Related DE68907718T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK018288A DK18288D0 (da) 1988-01-15 1988-01-15 Fremgangsmaade til pasteurisering af vandige oploesninger af faktor viii

Publications (2)

Publication Number Publication Date
DE68907718D1 true DE68907718D1 (de) 1993-08-26
DE68907718T2 DE68907718T2 (de) 1993-10-28

Family

ID=8090700

Family Applications (1)

Application Number Title Priority Date Filing Date
DE89901847T Expired - Fee Related DE68907718T2 (de) 1988-01-15 1989-01-13 Verfahren zur pasteurisierung von wässrigen lösungen von faktor viii.

Country Status (7)

Country Link
EP (1) EP0401232B1 (de)
AU (1) AU2944789A (de)
DE (1) DE68907718T2 (de)
DK (1) DK18288D0 (de)
FI (1) FI93796C (de)
NO (1) NO175622C (de)
WO (1) WO1989006547A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2664165B1 (fr) * 1990-07-03 1992-10-16 Lille Transfusion Sanguine Composition pour stabiliser le plasma sanguin en cours de pasteurisation.
CA2149212A1 (en) * 1992-11-17 1994-05-26 Mirella Ezban Rasmussen Improved recombinant production of proteins having factor viii:c activity
JP4071283B2 (ja) 1996-02-05 2008-04-02 旭化成クラレメディカル株式会社 滅菌保護剤及び滅菌方法
PT1820516E (pt) 1999-02-22 2013-10-31 Baxter Int Novas formulações de factor viii isentas de albumina
BRPI0921429B1 (pt) 2008-11-07 2022-07-12 Takeda Pharmaceutical Company Limited Formulação farmacêutica liofilizada estável, e, método para preparar um fator liofilizado estável

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT359646B (de) * 1979-04-19 1980-11-25 Immuno Ag Verfahren zur herstellung von nebenwirkungs- freien plasmafraktionen
DE2916711A1 (de) * 1979-04-25 1980-11-06 Behringwerke Ag Blutgerinnungsfaktoren und verfahren zu ihrer herstellung
DE3237512A1 (de) * 1982-10-09 1984-04-12 Behringwerke Ag, 3550 Marburg Verfahren zur pasteurisierung von antihaemophilem kryopraezipitat (ahk) und danach hergestelltes antihaemophiles kryopraezipitat
DE3336631A1 (de) * 1983-10-08 1985-04-18 Behringwerke Ag, 3550 Marburg Verfahren zur pasteurisierung von plasma oder von konzentraten der blutgerinnungsfaktoren ii, vii, ix und x
GB8505882D0 (en) * 1985-03-07 1985-04-11 Central Blood Lab Authority Purification of blood coagulation factor viii

Also Published As

Publication number Publication date
DK18288D0 (da) 1988-01-15
NO903144D0 (no) 1990-07-13
FI93796C (fi) 1995-06-12
FI93796B (fi) 1995-02-28
EP0401232A1 (de) 1990-12-12
FI903575A0 (fi) 1990-07-13
AU2944789A (en) 1989-08-11
WO1989006547A1 (en) 1989-07-27
EP0401232B1 (de) 1993-07-21
NO903144L (no) 1990-07-13
NO175622C (no) 1994-11-09
NO175622B (de) 1994-08-01
DE68907718T2 (de) 1993-10-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee