DE68905636D1 - Verfahren zur herstellung von optisch aktiven 2-arylpropionsaeuren. - Google Patents

Verfahren zur herstellung von optisch aktiven 2-arylpropionsaeuren.

Info

Publication number: DE68905636D1
Authority: DE; Germany
Prior art keywords: production; optically active; propionic acids; aryl propionic; alpha
Prior art date: 1988-01-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE8989400197T

Other languages

English (en)

Other versions

DE68905636T2 (de

Inventor

Edith Cerbelaud

Dominique Petre

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Rhone Poulenc Sante SA

Original Assignee

Rhone Poulenc Sante SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-01-27

Filing date

1989-01-25

Publication date

1993-05-06

1989-01-25 Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA

1993-05-06 Application granted granted Critical

1993-05-06 Publication of DE68905636D1 publication Critical patent/DE68905636D1/de

1993-09-23 Publication of DE68905636T2 publication Critical patent/DE68905636T2/de

2009-01-26 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

238000000034 method Methods 0.000 title abstract 2
150000004672 propanoic acids Chemical class 0.000 title 1
DOZZSWAOPDYVLH-UHFFFAOYSA-N 2-phenylpropanamide Chemical compound NC(=O)C(C)C1=CC=CC=C1 DOZZSWAOPDYVLH-UHFFFAOYSA-N 0.000 abstract 1
102000004190 Enzymes Human genes 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
150000007513 acids Chemical class 0.000 abstract 1
YPGCWEMNNLXISK-UHFFFAOYSA-N alpha-phenylpropionic acid Natural products OC(=O)C(C)C1=CC=CC=C1 YPGCWEMNNLXISK-UHFFFAOYSA-N 0.000 abstract 1
230000007062 hydrolysis Effects 0.000 abstract 1
238000006460 hydrolysis reaction Methods 0.000 abstract 1
244000005700 microbiome Species 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/52—Propionic acid; Butyric acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Analytical Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)

DE8989400197T 1988-01-27 1989-01-25 Verfahren zur herstellung von optisch aktiven 2-arylpropionsaeuren. Expired - Lifetime DE68905636T2 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8800923A FR2626288B1 (de)	1988-01-27	1988-01-27

Publications (2)

Publication Number	Publication Date
DE68905636D1 true DE68905636D1 (de)	1993-05-06
DE68905636T2 DE68905636T2 (de)	1993-09-23

Family

ID=9362685

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE8989400197T Expired - Lifetime DE68905636T2 (de)	1988-01-27	1989-01-25	Verfahren zur herstellung von optisch aktiven 2-arylpropionsaeuren.

Country Status (21)

Country	Link
US (1)	US5089405A (de)
EP (1)	EP0330529B1 (de)
JP (1)	JP2747310B2 (de)
KR (1)	KR890012004A (de)
CN (1)	CN1035847A (de)
AT (1)	ATE87664T1 (de)
AU (1)	AU616933B2 (de)
CA (1)	CA1340524C (de)
DE (1)	DE68905636T2 (de)
DK (1)	DK174729B1 (de)
ES (1)	ES2054039T3 (de)
FI (1)	FI95397C (de)
FR (1)	FR2626288B1 (de)
GR (1)	GR3007536T3 (de)
HU (1)	HU203792B (de)
IE (1)	IE63391B1 (de)
IL (1)	IL89089A (de)
NZ (1)	NZ227742A (de)
PT (1)	PT89553B (de)
RU (1)	RU1806201C (de)
ZA (1)	ZA89641B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4962124A (en) *	1987-11-17	1990-10-09	Analgesic Associates	Onset-hastened/enhanced antipyretic response
DK314989A (da) *	1988-06-27	1989-12-28	Asahi Chemical Ind	Fremgangsmaade til fremstilling af optisk aktive alfa-substituerede organiske syrer, samt mikroorganismer og enzymer anvendelige ved fremgangsmaaden
US5238828A (en) *	1988-08-29	1993-08-24	Idemitsu Kosan Company Limited	Method for the preparation of an optically active 2-substituted carboxylic acid
EP0356912A3 (de) *	1988-08-29	1991-09-18	Idemitsu Kosan Company Limited	Verfahren zur Herstellung von 2-substituierter, optisch aktiver Karbonsäure
DE3910024A1 (de) *	1989-03-28	1990-10-11	Basf Ag	Verfahren zur fermentativen herstellung von 2-(4-hydroxipenoxi-)propionsaeure
FR2655660B1 (fr) *	1989-12-11	1992-03-20	Rhone Poulenc Sante	Nouveaux polypeptides, sequences d'adn permettant leur expression, procede de preparation et leur utilisation.
DK161690D0 (da) *	1990-07-05	1990-07-05	Novo Nordisk As	Fremgangsmaade til fremstilling af enantiomere forbindelser
WO1992005275A1 (en) *	1990-09-20	1992-04-02	E.I. Du Pont De Nemours And Company	A process for the preparation of enantiomeric 2-alkanoic acids
US5593871A (en) *	1990-09-20	1997-01-14	E. I. Du Pont De Nemours And Company	Process for the preparation of enantiometric 2-alkanoic acid amides from nitriles
SG48037A1 (en) *	1990-11-14	1998-04-17	Nitto Chemical Industry Co Ltd	Biology process for production-alpha-hydroxyamide or alpha-hydroxy acid
FR2669643B1 (fr) *	1990-11-28	1995-04-28	Rhone Poulenc Chimie	Procede de synthese enzymatique d'adipate d'ammonium.
US5258305A (en) *	1991-09-13	1993-11-02	Nitto Chemical Industry Co., Ltd.	Manufacture of optically active 2-phenylpropionic acid and 2-phenylpropionamide from the nitrile using Rhodococcus equi
FR2687915B1 (fr) *	1992-02-28	1995-05-05	Rhone Poulenc Rorer Sa	Composition pharmaceutique utilisable comme analgesique contenant l'acide (benzoyl-3 phenyl)-2 propionique-(r).
US5273895A (en) *	1992-10-26	1993-12-28	Sepracor, Inc.	Enantioselective production of chiral carboxylic acids
WO1994020449A1 (en) *	1993-03-09	1994-09-15	Dompe'farmaceutici Spa	Salts of 2-(3-benzoylphenyl)propionic acid with achiral and chiral organic bases and pharmaceutical compositions thereof
US5476965A (en) *	1994-02-18	1995-12-19	Genencor International, Inc.	Enzymatic resolution of substituted 2-methyl-propionic acid
EP0826032A1 (de) *	1995-05-08	1998-03-04	Lonza Ag	Biotechnologisches verfahren zur herstellung von r-alpha-piperazincarbonsäure und s-alpha-piperazincarbonsäureamid
US5863750A (en) *	1996-12-18	1999-01-26	Cytec Tech Corp	Methods for the detoxification of nitrile and/or amide compounds
US6060265A (en) *	1996-12-18	2000-05-09	Cytec Technology Corporation	Methods for the detoxification of nitrile and/or amide compounds
CN101892283A (zh) *	2010-06-03	2010-11-24	华东理工大学	红球菌Rhodococcus ruber 4.1187催化制备光学纯(S)-(+)-2-苯基丙酸
CN103789791B (zh) *	2014-02-12	2016-08-17	华东师范大学	一种电化学合成具有光学活性的2-苯丙酸方法
CN109486897A (zh) *	2018-12-04	2019-03-19	湖南理工学院	一种立体选择性酶催化水解拆分2-苯基丙酸对映体的方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE1157237B (de) *	1961-09-16	1963-11-14	Bayer Ag	Verfahren zur Herstellung von optisch aktiven Phenoxyessigsaeuren
FR1342844A (fr) *	1961-09-16	1963-11-15	Bayer Ag	Procédé de préparation d'acides phénoxyacétiques substitués, optiquement actifs
JPS4913989A (de) *	1972-05-19	1974-02-06
FR2245585B1 (de) *	1973-09-19	1976-05-14	Anvar
JPS5446887A (en) *	1977-09-19	1979-04-13	Nitto Chem Ind Co Ltd	Preparation of acrylic acid or methacrylic acid
FR2447359A1 (fr) *	1979-01-24	1980-08-22	Anvar	Procede de preparation d'acides a-amines optiquement actifs par hydrolyse biologique de nitriles ou d'amides a-amines
US4366250A (en) *	1980-09-24	1982-12-28	Anvar	Preparation process of optically active α-aminated acids by biological hydrolysis of nitriles
NL8400312A (nl) *	1984-02-02	1985-09-02	Stamicarbon	Optisch aktief gesubstitueerd boterzuuramide alsmede werkwijze voor de optische scheiding van gesubstitueerd boterzuuramide.
JPS61162191A (ja) *	1985-01-11	1986-07-22	Nitto Chem Ind Co Ltd	微生物による有機酸類の製造法
DK261685A (da) *	1985-06-11	1986-12-12	Novo Industri As	Fremgangsmaade til fremstilling af optisk aktive, organiske forbindelser
HU197942B (en) *	1985-12-20	1989-06-28	Wisconsin Alumni Res Found	Process for producing (s)-alpha-methyl-aryl-acetic acids
GB8600245D0 (en) *	1986-01-07	1986-02-12	Shell Int Research	Preparation of 2-arylpropionic acids
AU599438B2 (en) *	1986-12-01	1990-07-19	Gist-Brocades N.V.	Process for the preparation of 2-arylpropionic acids
AU619249B2 (en) *	1988-02-25	1992-01-23	Istituto Guido Donegani S.P.A.	Process for the continuous biotechnological preparation of optical isomer s(+) of 2-(6-methoxy-2-naphthyl) propionic acid

1988
- 1988-01-27 FR FR8800923A patent/FR2626288B1/fr not_active Expired - Lifetime
1989
- 1989-01-25 DE DE8989400197T patent/DE68905636T2/de not_active Expired - Lifetime
- 1989-01-25 EP EP89400197A patent/EP0330529B1/de not_active Expired - Lifetime
- 1989-01-25 ES ES89400197T patent/ES2054039T3/es not_active Expired - Lifetime
- 1989-01-25 CN CN89101541A patent/CN1035847A/zh active Pending
- 1989-01-25 AT AT89400197T patent/ATE87664T1/de not_active IP Right Cessation
- 1989-01-26 RU SU894613309A patent/RU1806201C/ru active
- 1989-01-26 ZA ZA89641A patent/ZA89641B/xx unknown
- 1989-01-26 AU AU28828/89A patent/AU616933B2/en not_active Ceased
- 1989-01-26 JP JP1015207A patent/JP2747310B2/ja not_active Expired - Lifetime
- 1989-01-26 NZ NZ227742A patent/NZ227742A/en unknown
- 1989-01-26 CA CA000589237A patent/CA1340524C/fr not_active Expired - Lifetime
- 1989-01-26 IL IL89089A patent/IL89089A/xx unknown
- 1989-01-26 DK DK198900338A patent/DK174729B1/da not_active IP Right Cessation
- 1989-01-26 FI FI890388A patent/FI95397C/fi not_active IP Right Cessation
- 1989-01-26 HU HU89340A patent/HU203792B/hu not_active IP Right Cessation
- 1989-01-26 IE IE23889A patent/IE63391B1/en not_active IP Right Cessation
- 1989-01-26 KR KR1019890000809A patent/KR890012004A/ko not_active Application Discontinuation
- 1989-01-27 PT PT89553A patent/PT89553B/pt not_active IP Right Cessation
- 1989-07-26 US US07/385,084 patent/US5089405A/en not_active Expired - Lifetime
1993
- 1993-04-01 GR GR920403076T patent/GR3007536T3/el unknown

Also Published As

Publication number	Publication date
CA1340524C (fr)	1999-05-04
ZA89641B (en)	1989-10-25
FR2626288A1 (de)	1989-07-28
FI95397B (fi)	1995-10-13
NZ227742A (en)	1991-10-25
PT89553B (pt)	1994-02-28
AU2882889A (en)	1989-08-10
HU203792B (en)	1991-09-30
IL89089A0 (en)	1989-08-15
DK33889A (da)	1989-07-28
IE63391B1 (en)	1995-04-19
DE68905636T2 (de)	1993-09-23
JPH01309695A (ja)	1989-12-14
IE890238L (en)	1989-07-27
IL89089A (en)	1992-11-15
FR2626288B1 (de)	1990-05-18
CN1035847A (zh)	1989-09-27
GR3007536T3 (de)	1993-08-31
KR890012004A (ko)	1989-08-23
FI890388A (fi)	1989-07-28
DK174729B1 (da)	2003-10-06
ATE87664T1 (de)	1993-04-15
ES2054039T3 (es)	1994-08-01
PT89553A (pt)	1989-10-04
JP2747310B2 (ja)	1998-05-06
EP0330529A1 (de)	1989-08-30
HUT52821A (en)	1990-08-28
FI890388A0 (fi)	1989-01-26
RU1806201C (ru)	1993-03-30
EP0330529B1 (de)	1993-03-31
DK33889D0 (da)	1989-01-26
AU616933B2 (en)	1991-11-14
US5089405A (en)	1992-02-18
FI95397C (fi)	1996-01-25

Legal Events

Date	Code	Title	Description
1994-04-28	8364	No opposition during term of opposition
2006-10-26	8328	Change in the person/name/address of the agent	Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

Publication	Publication Date	Title
DE68905636D1 (de)	1993-05-06	Verfahren zur herstellung von optisch aktiven 2-arylpropionsaeuren.
DE68906904D1 (de)	1993-07-15	Verfahren zur herstellung von optisch aktiven 2-arylalkansaeuren.
DE59106289D1 (de)	1995-09-28	Verfahren zur Herstellung von Salzen des L-Ornithins.
ATE155172T1 (de)	1997-07-15	Verfahren zur herstellung einer mehrfach ungesättigten fettsäure des omega 9 typs
DE3882453D1 (de)	1993-08-26	Verfahren zur herstellung von ibuprofen.
DE3765157D1 (de)	1990-10-31	Verfahren zur herstellung von macrolid-derivaten.
ATE92532T1 (de)	1993-08-15	Verfahren zur herstellung von polysacchariden.
DE3785023D1 (de)	1993-04-29	Verfahren zur herstellung von arachidonsaeure.
ATE160820T1 (de)	1997-12-15	Verfahren zur herstellung von s-(1)-2-(3- benzoylphenyl)propionsäure durch enzymkatalinierte enantioselektive hydrolyse.
DE59007810D1 (de)	1995-01-12	Verfahren zur enzymatischen Spaltung von 2-Arylpropionsäurevinylestern.
ATE138414T1 (de)	1996-06-15	Verfahren zur herstellung von optisch aktiver 2- arylpropionsäure
DE68912236D1 (de)	1994-02-24	Verfahren zur Herstellung von hochgradig ungesättigten Fettsäuren.
ATE107364T1 (de)	1994-07-15	Verfahren zur herstellung von optisch aktiven 2- aryloxy- oder 2-arylthioalkansäuren.
ATE360087T1 (de)	2007-05-15	Verfahren zur racematspaltung von arylalkylcarbonsäureestern
ATE164190T1 (de)	1998-04-15	Verfahren zur herstellung von butantetracarboxylat
DE59007604D1 (de)	1994-12-08	Verfahren zur Herstellung von R-(+)-3-Oxocycloalkancarbonsäureniederalkylestern.
ATE49975T1 (de)	1990-02-15	Verfahren zur hydrolyse von substituierten methylendiphosphonsauren estern.
ATE190350T1 (de)	2000-03-15	Verfahren zur modifizierung von lipasen
DE68918776D1 (de)	1994-11-17	Verfahren zur Herstellung von Biokatalysatoren mit vorher fehlender stereoselektiver Enzymaktivität.
DE3780137D1 (de)	1992-08-06	Verfahren zur herstellung von optisch aktiven bicyclo (3.3.0) octandioncarbonsaeureestern.